Anna Alisi

Summary

Country: Italy

Publications

  1. pmc Multidrug resistance and cancer stem cells in neuroblastoma and hepatoblastoma
    Anna Alisi
    Liver Research Unit, Bambino Gesu Children s Hospital, IRCCS, Rome 00165, Italy
    Int J Mol Sci 14:24706-25. 2013
  2. pmc ADAR enzyme and miRNA story: a nucleotide that can make the difference
    Sara Tomaselli
    Laboratory of RNA Editing, Onco Haematology Department, Bambino Gesu Children s Hospital, IRCCS, Piazza S Onofrio 4, Rome 00165, Italy
    Int J Mol Sci 14:22796-816. 2013
  3. doi request reprint Transient elastography and serum biomarkers: two-step screening methods for liver fibrosis in non-alcoholic fatty liver disease before liver biopsy
    Anna Alisi
    Bambino Gesu Children s Hospital, IRCCS, Hepato Metabolic Disease Unit and Liver Research Unit, P le S Onofrio 4, 00165 Rome, Italy 390668592243
    Expert Opin Med Diagn 6:377-80. 2012
  4. pmc Focal adhesion kinase (FAK) mediates the induction of pro-oncogenic and fibrogenic phenotypes in hepatitis C virus (HCV)-infected cells
    Anna Alisi
    Liver Research Unit, Confocal Microscopy Facility of Bambino Gesù Children s Hospital, IRCCS, Rome, Italy
    PLoS ONE 7:e44147. 2012
  5. doi request reprint Redox homeostasis and posttranslational modifications/activity of phosphatase and tensin homolog in hepatocytes from rats with diet-induced hepatosteatosis
    Anna Alisi
    Unit of Metabolic and Autoimmune Liver Diseases of Bambino Gesù Children s Hospital IRCCS, Rome, Italy
    J Nutr Biochem 23:169-78. 2012
  6. doi request reprint Endotoxin and plasminogen activator inhibitor-1 serum levels associated with nonalcoholic steatohepatitis in children
    Anna Alisi
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    J Pediatr Gastroenterol Nutr 50:645-9. 2010
  7. doi request reprint Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver disease
    Anna Alisi
    Unit of Metabolic and Autoimmune Liver Diseases, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Lab Invest 91:283-93. 2011
  8. doi request reprint Liver fibrosis in paediatric liver diseases
    Anna Alisi
    Unit of Liver Research, Bambino Gesu Children s Hospital, IRCCS, P le S Onofrio 4, 00165 Rome, Italy
    Best Pract Res Clin Gastroenterol 25:259-68. 2011
  9. doi request reprint Markers of activated inflammatory cells correlate with severity of liver damage in children with nonalcoholic fatty liver disease
    Rita De Vito
    Unit of Pathology, IRCCS, Rome, Italy
    Int J Mol Med 30:49-56. 2012
  10. doi request reprint Severity of liver injury and atherogenic lipid profile in children with nonalcoholic fatty liver disease
    Valerio Nobili
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Pediatr Res 67:665-70. 2010

Collaborators

Detail Information

Publications53

  1. pmc Multidrug resistance and cancer stem cells in neuroblastoma and hepatoblastoma
    Anna Alisi
    Liver Research Unit, Bambino Gesu Children s Hospital, IRCCS, Rome 00165, Italy
    Int J Mol Sci 14:24706-25. 2013
    ..Finally, some novel approaches, such as concomitant targeting of multiple key transcription factors governing the stemness of CSCs, as well as nanoparticle-based approaches will also be briefly addressed. ..
  2. pmc ADAR enzyme and miRNA story: a nucleotide that can make the difference
    Sara Tomaselli
    Laboratory of RNA Editing, Onco Haematology Department, Bambino Gesu Children s Hospital, IRCCS, Piazza S Onofrio 4, Rome 00165, Italy
    Int J Mol Sci 14:22796-816. 2013
    ..We then review the more recent findings about the impact of ADAR-mediated activity on the miRNA pathway in terms of biogenesis, target recognition, and gene expression regulation. ..
  3. doi request reprint Transient elastography and serum biomarkers: two-step screening methods for liver fibrosis in non-alcoholic fatty liver disease before liver biopsy
    Anna Alisi
    Bambino Gesu Children s Hospital, IRCCS, Hepato Metabolic Disease Unit and Liver Research Unit, P le S Onofrio 4, 00165 Rome, Italy 390668592243
    Expert Opin Med Diagn 6:377-80. 2012
    ....
  4. pmc Focal adhesion kinase (FAK) mediates the induction of pro-oncogenic and fibrogenic phenotypes in hepatitis C virus (HCV)-infected cells
    Anna Alisi
    Liver Research Unit, Confocal Microscopy Facility of Bambino Gesù Children s Hospital, IRCCS, Rome, Italy
    PLoS ONE 7:e44147. 2012
    ..In conclusion, our findings demonstrate that HCV, through FAK activation, may promote cytoskeletal reorganization and a pro-oncogenic phenotype in hepatocyte-like cells, and a fibrogenic phenotype in HSCs...
  5. doi request reprint Redox homeostasis and posttranslational modifications/activity of phosphatase and tensin homolog in hepatocytes from rats with diet-induced hepatosteatosis
    Anna Alisi
    Unit of Metabolic and Autoimmune Liver Diseases of Bambino Gesù Children s Hospital IRCCS, Rome, Italy
    J Nutr Biochem 23:169-78. 2012
    ....
  6. doi request reprint Endotoxin and plasminogen activator inhibitor-1 serum levels associated with nonalcoholic steatohepatitis in children
    Anna Alisi
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    J Pediatr Gastroenterol Nutr 50:645-9. 2010
    ..We investigated the association between serum levels of endotoxin, proinflammatory molecules, and histology in children with NAFLD...
  7. doi request reprint Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver disease
    Anna Alisi
    Unit of Metabolic and Autoimmune Liver Diseases, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Lab Invest 91:283-93. 2011
    ..In conclusion, we highlight for the first time the potential involvement of novel determinants (miRNAs and proteins) in the molecular pathogenesis of diet-induced NAFLD...
  8. doi request reprint Liver fibrosis in paediatric liver diseases
    Anna Alisi
    Unit of Liver Research, Bambino Gesu Children s Hospital, IRCCS, P le S Onofrio 4, 00165 Rome, Italy
    Best Pract Res Clin Gastroenterol 25:259-68. 2011
    ..Furthermore, we describe use of liver biopsy in diagnosis and staging of liver fibrosis, list the alternative non-invasive techniques that have an emerging role in the assessment of liver fibrosis, and propose a management algorithm...
  9. doi request reprint Markers of activated inflammatory cells correlate with severity of liver damage in children with nonalcoholic fatty liver disease
    Rita De Vito
    Unit of Pathology, IRCCS, Rome, Italy
    Int J Mol Med 30:49-56. 2012
    ..Moreover, a decrease in CD3+ cells may be involved in the pathogenesis of liver damage. Future studies should evaluate whether it can predict the progression of liver disease independently of established histological scores...
  10. doi request reprint Severity of liver injury and atherogenic lipid profile in children with nonalcoholic fatty liver disease
    Valerio Nobili
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Pediatr Res 67:665-70. 2010
    ....
  11. doi request reprint Levels of serum ceruloplasmin associate with pediatric nonalcoholic fatty liver disease
    Valerio Nobili
    Unit of Liver Research, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    J Pediatr Gastroenterol Nutr 56:370-5. 2013
    ..We investigated whether transition metals and their related proteins were related to NAFLD symptoms and their underlying processes...
  12. ncbi request reprint Glutathionylation of p65NF-kappaB correlates with proliferating/apoptotic hepatoma cells exposed to pro- and anti-oxidants
    Anna Alisi
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, I 00165 Rome, Italy
    Int J Mol Med 24:319-26. 2009
    ..In conclusion, our findings suggest that glutathionylation inhibits NF-kappaB activity causing reduced hepatocyte survival, which is common in several liver diseases...
  13. pmc Emodin prevents intrahepatic fat accumulation, inflammation and redox status imbalance during diet-induced hepatosteatosis in rats
    Anna Alisi
    Liver Unit of Bambino Gesù Children s Hospital, IRCCS, Rome 00165, Italy E Mails S C N P D G V N
    Int J Mol Sci 13:2276-89. 2012
    ..These findings are promising, proposing emodin as a possible hindrance to progression of hepatosteatosis into steatohepatitis...
  14. doi request reprint Relationship between portal chronic inflammation and disease severity in paediatric non-alcoholic fatty liver disease
    Anna Alisi
    Liver Unit, Pediatric Hospital Bambino Gesu, IRCCS, Rome, Italy
    Dig Liver Dis 43:143-6. 2011
    ..The non-alcoholic steato-hepatitis Clinical Research Network has recently shown that portal chronic inflammation is associated with liver fibrosis in American children with non-alcoholic fatty liver disease...
  15. doi request reprint Docosahexaenoic acid supplementation decreases liver fat content in children with non-alcoholic fatty liver disease: double-blind randomised controlled clinical trial
    Valerio Nobili
    Unit of Metabolic and Autoimmune Liver Diseases, Bambino Gesu Children s Hospital IRCCS, Square S Onofrio 4, Rome, Italy
    Arch Dis Child 96:350-3. 2011
    ..To investigate whether dietary supplementation with docosahexaenoic acid (DHA) decreases liver fat content in children with non-alcoholic fatty liver disease (NAFLD)...
  16. doi request reprint Role of docosahexaenoic Acid treatment in improving liver histology in pediatric nonalcoholic Fatty liver disease
    Valerio Nobili
    Unit of Liver Research, Bambino Gesu Children s Hospital, Rome, Italy
    PLoS ONE 9:e88005. 2014
    ..Our aim was to investigate in pediatric NAFLD the mechanisms underlying the effects of DHA administration on histo-pathological aspects, GPR120 expression, hepatic progenitor cell activation and macrophage pool...
  17. doi request reprint Hepatic progenitor cells activation, fibrosis, and adipokines production in pediatric nonalcoholic fatty liver disease
    Valerio Nobili
    Unit of Liver Research, Bambino Gesu Children s Hospital, Instituto di Ricovero e Cura a Carattere Scientifico IRCCS, Rome, Italy
    Hepatology 56:2142-53. 2012
    ..432; P < 0.05). GLP-1 was overexpressed in HPCs of pNAFLD patients, and GLP-1 expression was related to degree of steatosis (r = 0.577; P < 0.05) and NAS (r = 0.594; P < 0.01)...
  18. doi request reprint Transient elastography for assessment of fibrosis in paediatric liver disease
    Valerio Nobili
    Liver Unit, Research Institute, Bambino Gesu Children s Hospital, Piazza S Onofrio 4, 00165 Rome, Italy
    Pediatr Radiol 41:1232-8. 2011
    ....
  19. doi request reprint Metformin use in children with nonalcoholic fatty liver disease: an open-label, 24-month, observational pilot study
    Valerio Nobili
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Clin Ther 30:1168-76. 2008
    ..There is no consensus on the treatment of pediatric nonalcoholic fatty liver disease (NAFLD). However, in a small pilot study conducted in 10 children, metformin has been proposed to be effective...
  20. doi request reprint Retinol-binding protein 4: a promising circulating marker of liver damage in pediatric nonalcoholic fatty liver disease
    Valerio Nobili
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Clin Gastroenterol Hepatol 7:575-9. 2009
    ..We tested the serum levels of RBP4 to assess their associations with the metabolic profile and histologic features in a large well-characterized group of children with NAFLD...
  21. doi request reprint Hyaluronic acid predicts hepatic fibrosis in children with nonalcoholic fatty liver disease
    Valerio Nobili
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Transl Res 156:229-34. 2010
    ..Additional studies are needed to test whether HA can be employed to predict liver fibrosis in pediatric populations with similar and lower prevalence of liver fibrosis...
  22. doi request reprint Paediatric nonalcoholic fatty liver disease
    Anna Alisi
    Liver Research Unit, Bambino Gesu Children s Hospital, IRCCS, and Department of Health Sciences, University of Rome Foro Italico, IRCCS, Rome, Italy
    Curr Opin Gastroenterol 29:279-84. 2013
    ..During the last decade, NAFLD has reached epidemic proportions in overweight/obese children. In this manuscript, we review all recent advances in paediatric NAFLD...
  23. doi request reprint Non-alcoholic fatty liver disease and metabolic syndrome in adolescents: pathogenetic role of genetic background and intrauterine environment
    Anna Alisi
    Liver Research Unit, Bambino Gesu Children s Hospital, IRCCS, Rome, Italy
    Ann Med 44:29-40. 2012
    ..We here summarize the most recent epidemiological data on the incidence of both diseases in adolescents, and several aspects linking MetS with NAFLD, discussing the possible role played by genetics and intrauterine environment...
  24. doi request reprint Early interplay of intra-hepatic iron and insulin resistance in children with non-alcoholic fatty liver disease
    Melania Manco
    Laboratorio di Malattie Epatiche Auto Immuni e Metaboliche, Ospedale Pediatrico Bambino Gesu, IRCCS, Roma, Italy
    J Hepatol 55:647-53. 2011
    ..The aim of the study was to assess intra-hepatic iron in young patients with non-alcoholic fatty liver disease (NAFLD) and its association with insulin resistance and severity of liver damage...
  25. doi request reprint A 360-degree overview of paediatric NAFLD: recent insights
    Valerio Nobili
    Hepato Metabolic Disease Unit and Liver Research Unit, Bambino Gesu Children s Hospital, IRCCS, P le S Onofrio 4, 00165 Rome, Italy
    J Hepatol 58:1218-29. 2013
    ..In this review, we discuss the recent advances made in genetics, etiopathogenesis, diagnosis, and therapeutic management of NAFLD, focusing especially on the obesity-related steatotic liver condition...
  26. doi request reprint Circulating miRNA profiling to identify biomarkers of dysmetabolism
    Sara Tomaselli
    RNA Editing Unit, Bambino Gesu Children s Hospital, IRCCS, Rome, Italy
    Biomark Med 6:729-42. 2012
    ..Afterwards, we discuss recent data regarding altered intracellular and circulating miRNAs associated with specific metabolic disorders...
  27. doi request reprint Nonalcoholic fatty liver in children and adolescents: an overview
    Claudia Della Corte
    Hepato Metabolic Division, Bambino Gesu Children s Hospital, IRCCS, Rome, Italy
    J Adolesc Health 51:305-12. 2012
    ..In this article, we briefly review the current knowledge and ideas concerning pediatric nonalcoholic fatty liver disease, and discuss the new perspective therapies...
  28. ncbi request reprint Liver fibrosis and therapeutic strategies: the goal for improving metabolism
    Clara Balsano
    Laboratory of Molecular Virology and Oncology, A Cesalpino Foundation, University of Rome, Rome, Italy
    Curr Drug Targets 10:505-12. 2009
    ..Clinical relevance of drugs correcting these metabolic disturbances in the reversion of liver fibrosis will also be discussed...
  29. doi request reprint Hepatitis C virus and alcohol: same mitotic targets but different signaling pathways
    Anna Alisi
    Laboratory of Molecular Virology and Oncology, Fondazione A Cesalpino, University of Rome, Rome, V le del Policlinico 155, 00161 Rome, Italy
    J Hepatol 54:956-63. 2011
    ..Our study aims at investigating changes in expression of the above mentioned proteins and related intracellular pathways, in in vitro and in vivo models of both HCV- and alcohol- dependent HCCs...
  30. doi request reprint Non-alcoholic fatty liver disease in children now: lifestyle changes and pharmacologic treatments
    Anna Alisi
    Unit of Liver Research, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Nutrition 28:722-6. 2012
    ..We also emphasize several advantages of the pharmacologic treatments adopted or adoptable in combination with lifestyle interventions in children with NAFLD...
  31. doi request reprint Expert opinion on current therapies for nonalcoholic fatty liver disease
    Claudia Della Corte
    Bambino Gesu Children s Hospital, Liver Research Unit, IRCCS, Piazzale S Onofrio 4, Rome, Italy
    Expert Opin Pharmacother 12:1901-11. 2011
    ..Therefore, new treatments based on pathogenetic mechanisms leading to NAFLD are under evaluation to establish an effective pharmacological therapy for this disorder...
  32. ncbi request reprint Oxidative stress parameters in paediatric non-alcoholic fatty liver disease
    Valerio Nobili
    Department of Hepatogastroenterology, Bambino Gesu Children s Hospital, Rome, Italy
    Int J Mol Med 26:471-6. 2010
    ..9; 95= CI 1.5-113.8; p=0.013) of a NAFLD activity score (NAS) >or=5. These results demonstrate that oxidative stress has an high prevalence in children with NAFLD and is associated with an increased severity of steatohepatitis...
  33. pmc The pediatric NAFLD fibrosis index: a predictor of liver fibrosis in children with non-alcoholic fatty liver disease
    Valerio Nobili
    Department of Hepatogastroenterology and Nutrition, Pediatric Hospital IRCCS Bambino Gesù, Via S, Onofrio 4, 00165 Rome, Italy
    BMC Med 7:21. 2009
    ..Here, we developed a simple algorithm for the prediction of liver fibrosis in children with NAFLD followed at a tertiary care center...
  34. pmc The use of ultrasound in clinical setting for children affected by NAFLD: is it safe and accurate?
    Valerio Nobili
    Unit of Liver Research of Bambino Gesù Children s Hospital, IRCCS, P le S Onofrio 4, 00165 Rome, Italy
    Ital J Pediatr 37:36. 2011
    ..Many non-invasive diagnostic tools have been evaluated so far. Recently the utility of ultrasonography for non-invasive diagnosis and estimation of hepatic steatosis has been demonstrated in a large prospective pediatric study...
  35. ncbi request reprint Involvement of PI3K in HCV-related lymphoproliferative disorders
    Anna Alisi
    Laboratory of Molecular Virology and Oncology, Fondazione A Cesalpino, University of Rome La Sapienza, Rome, Italy
    J Cell Physiol 214:396-404. 2008
    ....
  36. doi request reprint Pediatric nonalcoholic fatty liver disease: a multidisciplinary approach
    Anna Alisi
    Liver Research Unit, Bambino Gesu Children s Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Piazza Sant Onofrio 4, 00165 Rome, Italy
    Nat Rev Gastroenterol Hepatol 9:152-61. 2012
    ..In this Review, we provide an overview of current concepts in epidemiology, histological features, etiopathogenesis, diagnosis and treatment of NAFLD in children and adolescents...
  37. doi request reprint Nonalcoholic fatty liver disease in children
    Anna Alisi
    Unit of Metabolic and Autoimmune Liver Diseases, Pediatric Hospital IRCCS Bambino Gesù, Rome, Italy
    Curr Opin Clin Nutr Metab Care 13:397-402. 2010
    ..The intent of this review is to provide a concise overview of all recent acquisitions in terms of therapies and early noninvasive diagnostic approaches for nonalcoholic fatty liver disease (NAFLD) in children...
  38. doi request reprint Microarray technology: a promising tool in nutrigenomics
    Andrea Masotti
    Bambino Gesu Children s Hospital, Research Institute IRCCS, Rome, Italy
    Crit Rev Food Sci Nutr 50:693-8. 2010
    ..This critical review gives an overview of the clinical relevance of a nutritional approach to several important diseases, and proposes the use of microarray for nutrigenomic studies...
  39. ncbi request reprint Association between type two diabetes and non-alcoholic fatty liver disease in youth
    Anna Alisi
    Unit of Hepatology Bambino Gesù Hospital and Research Institute Piazza San Onofrio 4 00165 Rome Italy
    Ann Hepatol 8:S44-50. 2009
    ..Epidemiological studies support a close association between type 2 diabetes and fatty liver disease. We review the most recent epidemiological data on prevalence of both diseases in youth and their association...
  40. pmc EZH2 down-regulation exacerbates lipid accumulation and inflammation in in vitro and in vivo NAFLD
    Serena Vella
    Department of Oncohematology, Bambino Gesu Children s Hospital, IRCCS, Rome 00165, Italy
    Int J Mol Sci 14:24154-68. 2013
    ..In conclusion, the results of this study suggest that the defective activity of EZH2 can enhance the NAFLD development by favouring steatosis and the de-repression of the inflammatory genes and that of specific microRNAs. ..
  41. doi request reprint The I148M variant of PNPLA3 reduces the response to docosahexaenoic acid in children with non-alcoholic fatty liver disease
    Valerio Nobili
    1 Hepatometabolic Unit, Bambino Gesu Children s Hospital, Roma, Italy
    J Med Food 16:957-60. 2013
    ..We conclude that the 148M allele of PNPLA3 is associated with lower response, and the 148I allele with greater response, to DHA supplementation in children with NAFLD...
  42. ncbi request reprint Antioxidant effects of natural bioactive compounds
    Clara Balsano
    Laboratory of Molecular Virology and Oncology, Fondazione A Cesalpino, University of Rome, Rome, Italy
    Curr Pharm Des 15:3063-73. 2009
    ..In this review we present an outline of main roles of ROS in biological processes and diseases and how natural bioactive compounds of fruits and vegetables determine their health-promoting properties...
  43. pmc Intrauterine growth retardation and nonalcoholic Fatty liver disease in children
    Anna Alisi
    Liver Research Unit, Bambino Gesu Children s Hospital and Research Institute, 00165 Rome, Italy
    Int J Endocrinol 2011:269853. 2011
    ..In this paper, we outline clinical and experimental evidences of the association between IUGR, metabolic syndrome, insulin resistance, and NAFLD and discuss on a possible management to avoid the risk of MS in adulthood...
  44. ncbi request reprint Low birth weight and catch-up-growth associated with metabolic syndrome: a ten year systematic review
    Valerio Nobili
    Bambino Gesu Children s Hospital and Research Institute, Dept of Hepato Gastroenterology and Nutrition, Rome, Italy
    Pediatr Endocrinol Rev 6:241-7. 2008
    ..study the potential role of an alternative nutritional approach to side effects of catch-up-growth...
  45. doi request reprint Meta-omic platforms to assist in the understanding of NAFLD gut microbiota alterations: tools and applications
    Federica del Chierico
    Unit of Parasitology, Bambino Gesu Children s Hospital, IRCCS, Piazza Sant Onofrio, 4, Rome 00165, Italy
    Int J Mol Sci 15:684-711. 2014
    ..Such complexity can only be revealed using systems biology, which can integrate clinical phenomics and gut microbiota data. ..
  46. doi request reprint Expression of multidrug resistance-associated proteins in paediatric soft tissue sarcomas before and after chemotherapy
    Arianna Citti
    Pathology Department, IRCCS, Ospedale Pediatrico Bambino Gesu, I 00165 Rome, Italy
    Int J Oncol 41:117-24. 2012
    ....
  47. doi request reprint LPIN1 rs13412852 polymorphism in pediatric nonalcoholic fatty liver disease
    Luca Valenti
    Department of Internal Medicine, Universita degli Studi, Ospedale Maggiore Policlinico Ca Granda IRCCS, Milan, Italy
    J Pediatr Gastroenterol Nutr 54:588-93. 2012
    ..The aim of the present study was to evaluate whether the lipin1 rs13412852 C>T polymorphism is associated with nonalcoholic steatohepatitis and fibrosis in pediatric Italian patients with nonalcoholic fatty liver disease (NAFLD)...
  48. doi request reprint Novel Tween 20 derivatives enable the formation of efficient pH-sensitive drug delivery vehicles for human hepatoblastoma
    Andrea Masotti
    Gene Expression Microarrays Laboratory, IRCCS Children s Hospital Bambino Gesù, 00165 Rome, Italy
    Bioorg Med Chem Lett 20:3021-5. 2010
    ..These derivatives form pH-sensitive vesicles and translocate small molecules into cells. The reported systems are efficient drug delivery systems for human hepatoblastoma cells...
  49. doi request reprint Autoimmune hepatitis type 2 following anti-papillomavirus vaccination in a 11-year-old girl
    Claudia Della Corte
    Unit of Liver Research, Department of Pathology, Bambino Gesu Children s Hospital, IRCCS, P le S Onofrio 4, 00165 Rome, Italy
    Vaccine 29:4654-6. 2011
    ....
  50. doi request reprint Is there any link between dietary pattern and development of nonalcoholic fatty liver disease in adolescence? An expert review
    Daniela Liccardo
    Hepato Metabolic Disease Unit, Rome, Italy
    Expert Rev Gastroenterol Hepatol 7:601-4. 2013
    ..On the contrary, a western dietary pattern at 14 years in this cohort was associated with an increased risk of NAFLD at 17 years, particularly in obese adolescents...
  51. ncbi request reprint Integrated bioinformatics analysis of microRNA expression profiles for an in-depth understanding of pathogenic mechanisms in non-alcoholic fatty liver disease
    Andrea Masotti
    Gene Expression Microarrays Laboratory, Rome, Italy Liver Research Unit of Bambino Gesù Children s Hospital and Research Institute, Rome, Italy
    J Gastroenterol Hepatol 27:187-8. 2012
    ..See article in J. Gastroenterol. Hepatol. 2012; 27: 331-340...
  52. ncbi request reprint Thyroid status affects rat liver regeneration after partial hepatectomy by regulating cell cycle and apoptosis
    Anna Alisi
    Department of Cellular and Developmental Biology, University La Sapienza, Rome, Italy
    Cell Physiol Biochem 15:69-76. 2005
    ..In conclusion our data demonstrate that thyroid status can affects liver regeneration, altering the expression and the activity of the proteins involved in the control of cell cycle and growth arrest...
  53. pmc Pediatric non-alcoholic fatty liver disease: Preventive and therapeutic value of lifestyle intervention
    Valerio Nobili
    Liver Unit, Research Institute, , S Onofrio 4 Square, 00165 Rome, Italy
    World J Gastroenterol 15:6017-22. 2009
    ..Here, we outline the clinical course, pathogenesis and management of NAFLD in children, highlighting the preventive and therapeutic value of lifestyle intervention...