Anna Alisi

Summary

Country: Italy

Publications

  1. ncbi Low birth weight and catch-up-growth associated with metabolic syndrome: a ten year systematic review
    Valerio Nobili
    Bambino Gesu Children s Hospital and Research Institute, Dept of Hepato Gastroenterology and Nutrition, Rome, Italy
    Pediatr Endocrinol Rev 6:241-7. 2008
  2. pmc The pediatric NAFLD fibrosis index: a predictor of liver fibrosis in children with non-alcoholic fatty liver disease
    Valerio Nobili
    Department of Hepatogastroenterology and Nutrition, Pediatric Hospital IRCCS Bambino Gesù, Via S, Onofrio 4, 00165 Rome, Italy
    BMC Med 7:21. 2009
  3. ncbi Glutathionylation of p65NF-kappaB correlates with proliferating/apoptotic hepatoma cells exposed to pro- and anti-oxidants
    Anna Alisi
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, I 00165 Rome, Italy
    Int J Mol Med 24:319-26. 2009
  4. ncbi Association between type two diabetes and non-alcoholic fatty liver disease in youth
    Anna Alisi
    Unit of Hepatology Bambino Gesù Hospital and Research Institute Piazza San Onofrio 4 00165 Rome Italy
    Ann Hepatol 8:S44-50. 2009
  5. doi Severity of liver injury and atherogenic lipid profile in children with nonalcoholic fatty liver disease
    Valerio Nobili
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Pediatr Res 67:665-70. 2010
  6. doi Levels of serum ceruloplasmin associate with pediatric nonalcoholic fatty liver disease
    Valerio Nobili
    Unit of Liver Research, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    J Pediatr Gastroenterol Nutr 56:370-5. 2013
  7. doi Relationship between portal chronic inflammation and disease severity in paediatric non-alcoholic fatty liver disease
    Anna Alisi
    Liver Unit, Pediatric Hospital Bambino Gesu, IRCCS, Rome, Italy
    Dig Liver Dis 43:143-6. 2011
  8. ncbi Endotoxin and plasminogen activator inhibitor-1 serum levels associated with nonalcoholic steatohepatitis in children
    Anna Alisi
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    J Pediatr Gastroenterol Nutr 50:645-9. 2010
  9. doi Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver disease
    Anna Alisi
    Unit of Metabolic and Autoimmune Liver Diseases, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Lab Invest 91:283-93. 2011
  10. doi Transient elastography for assessment of fibrosis in paediatric liver disease
    Valerio Nobili
    Liver Unit, Research Institute, Bambino Gesu Children s Hospital, Piazza S Onofrio 4, 00165 Rome, Italy
    Pediatr Radiol 41:1232-8. 2011

Collaborators

Detail Information

Publications22

  1. ncbi Low birth weight and catch-up-growth associated with metabolic syndrome: a ten year systematic review
    Valerio Nobili
    Bambino Gesu Children s Hospital and Research Institute, Dept of Hepato Gastroenterology and Nutrition, Rome, Italy
    Pediatr Endocrinol Rev 6:241-7. 2008
    ..study the potential role of an alternative nutritional approach to side effects of catch-up-growth...
  2. pmc The pediatric NAFLD fibrosis index: a predictor of liver fibrosis in children with non-alcoholic fatty liver disease
    Valerio Nobili
    Department of Hepatogastroenterology and Nutrition, Pediatric Hospital IRCCS Bambino Gesù, Via S, Onofrio 4, 00165 Rome, Italy
    BMC Med 7:21. 2009
    ..Here, we developed a simple algorithm for the prediction of liver fibrosis in children with NAFLD followed at a tertiary care center...
  3. ncbi Glutathionylation of p65NF-kappaB correlates with proliferating/apoptotic hepatoma cells exposed to pro- and anti-oxidants
    Anna Alisi
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, I 00165 Rome, Italy
    Int J Mol Med 24:319-26. 2009
    ..In conclusion, our findings suggest that glutathionylation inhibits NF-kappaB activity causing reduced hepatocyte survival, which is common in several liver diseases...
  4. ncbi Association between type two diabetes and non-alcoholic fatty liver disease in youth
    Anna Alisi
    Unit of Hepatology Bambino Gesù Hospital and Research Institute Piazza San Onofrio 4 00165 Rome Italy
    Ann Hepatol 8:S44-50. 2009
    ..Epidemiological studies support a close association between type 2 diabetes and fatty liver disease. We review the most recent epidemiological data on prevalence of both diseases in youth and their association...
  5. doi Severity of liver injury and atherogenic lipid profile in children with nonalcoholic fatty liver disease
    Valerio Nobili
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Pediatr Res 67:665-70. 2010
    ....
  6. doi Levels of serum ceruloplasmin associate with pediatric nonalcoholic fatty liver disease
    Valerio Nobili
    Unit of Liver Research, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    J Pediatr Gastroenterol Nutr 56:370-5. 2013
    ..We investigated whether transition metals and their related proteins were related to NAFLD symptoms and their underlying processes...
  7. doi Relationship between portal chronic inflammation and disease severity in paediatric non-alcoholic fatty liver disease
    Anna Alisi
    Liver Unit, Pediatric Hospital Bambino Gesu, IRCCS, Rome, Italy
    Dig Liver Dis 43:143-6. 2011
    ..The non-alcoholic steato-hepatitis Clinical Research Network has recently shown that portal chronic inflammation is associated with liver fibrosis in American children with non-alcoholic fatty liver disease...
  8. ncbi Endotoxin and plasminogen activator inhibitor-1 serum levels associated with nonalcoholic steatohepatitis in children
    Anna Alisi
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    J Pediatr Gastroenterol Nutr 50:645-9. 2010
    ..We investigated the association between serum levels of endotoxin, proinflammatory molecules, and histology in children with NAFLD...
  9. doi Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver disease
    Anna Alisi
    Unit of Metabolic and Autoimmune Liver Diseases, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Lab Invest 91:283-93. 2011
    ..In conclusion, we highlight for the first time the potential involvement of novel determinants (miRNAs and proteins) in the molecular pathogenesis of diet-induced NAFLD...
  10. doi Transient elastography for assessment of fibrosis in paediatric liver disease
    Valerio Nobili
    Liver Unit, Research Institute, Bambino Gesu Children s Hospital, Piazza S Onofrio 4, 00165 Rome, Italy
    Pediatr Radiol 41:1232-8. 2011
    ....
  11. doi Non-alcoholic fatty liver disease in children now: lifestyle changes and pharmacologic treatments
    Anna Alisi
    Unit of Liver Research, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Nutrition 28:722-6. 2012
    ..We also emphasize several advantages of the pharmacologic treatments adopted or adoptable in combination with lifestyle interventions in children with NAFLD...
  12. doi Metformin use in children with nonalcoholic fatty liver disease: an open-label, 24-month, observational pilot study
    Valerio Nobili
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Clin Ther 30:1168-76. 2008
    ..There is no consensus on the treatment of pediatric nonalcoholic fatty liver disease (NAFLD). However, in a small pilot study conducted in 10 children, metformin has been proposed to be effective...
  13. doi Hyaluronic acid predicts hepatic fibrosis in children with nonalcoholic fatty liver disease
    Valerio Nobili
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Transl Res 156:229-34. 2010
    ..Additional studies are needed to test whether HA can be employed to predict liver fibrosis in pediatric populations with similar and lower prevalence of liver fibrosis...
  14. doi Novel Tween 20 derivatives enable the formation of efficient pH-sensitive drug delivery vehicles for human hepatoblastoma
    Andrea Masotti
    Gene Expression Microarrays Laboratory, IRCCS Children s Hospital Bambino Gesù, 00165 Rome, Italy
    Bioorg Med Chem Lett 20:3021-5. 2010
    ..These derivatives form pH-sensitive vesicles and translocate small molecules into cells. The reported systems are efficient drug delivery systems for human hepatoblastoma cells...
  15. ncbi Early interplay of intra-hepatic iron and insulin resistance in children with non-alcoholic fatty liver disease
    Melania Manco
    Laboratorio di Malattie Epatiche Auto Immuni e Metaboliche, Ospedale Pediatrico Bambino Gesu, IRCCS, Roma, Italy
    J Hepatol 55:647-53. 2011
    ..The aim of the study was to assess intra-hepatic iron in young patients with non-alcoholic fatty liver disease (NAFLD) and its association with insulin resistance and severity of liver damage...
  16. doi Liver fibrosis in paediatric liver diseases
    Anna Alisi
    Unit of Liver Research, Bambino Gesu Children s Hospital, IRCCS, P le S Onofrio 4, 00165 Rome, Italy
    Best Pract Res Clin Gastroenterol 25:259-68. 2011
    ..Furthermore, we describe use of liver biopsy in diagnosis and staging of liver fibrosis, list the alternative non-invasive techniques that have an emerging role in the assessment of liver fibrosis, and propose a management algorithm...
  17. doi Autoimmune hepatitis type 2 following anti-papillomavirus vaccination in a 11-year-old girl
    Claudia Della Corte
    Unit of Liver Research, Department of Pathology, Bambino Gesu Children s Hospital, IRCCS, P le S Onofrio 4, 00165 Rome, Italy
    Vaccine 29:4654-6. 2011
    ....
  18. pmc Intrauterine growth retardation and nonalcoholic Fatty liver disease in children
    Anna Alisi
    Liver Research Unit, Bambino Gesu Children s Hospital and Research Institute, 00165 Rome, Italy
    Int J Endocrinol 2011:269853. 2011
    ..In this paper, we outline clinical and experimental evidences of the association between IUGR, metabolic syndrome, insulin resistance, and NAFLD and discuss on a possible management to avoid the risk of MS in adulthood...
  19. ncbi A 4-polymorphism risk score predicts steatohepatitis in children with nonalcoholic Fatty liver disease
    Valerio Nobili
    Liver Research Unit, Bambino Gesu Children s Hospital and Research Institute, Roma Department of Pathophysiology and Transplantation, Section Internal Medicine, Universita degli Studi di Milano, Fondazione Cà Granda IRCCS Ospedale Maggiore Policlinico, Milan Scientific Direction, Bambino Gesu Children s Hospital and Research Institute, Roma, Italy
    J Pediatr Gastroenterol Nutr 58:632-6. 2014
    ..Because diagnosis still requires liver biopsy, there is urgent need of developing noninvasive early markers. The aim of the present study was to assess whether the simultaneous detection of genetic risk factors could predict NASH...
  20. doi Retinol-binding protein 4: a promising circulating marker of liver damage in pediatric nonalcoholic fatty liver disease
    Valerio Nobili
    Liver Unit, Bambino Gesu Children s Hospital and Research Institute, Rome, Italy
    Clin Gastroenterol Hepatol 7:575-9. 2009
    ..We tested the serum levels of RBP4 to assess their associations with the metabolic profile and histologic features in a large well-characterized group of children with NAFLD...
  21. doi LPIN1 rs13412852 polymorphism in pediatric nonalcoholic fatty liver disease
    Luca Valenti
    Department of Internal Medicine, Universita degli Studi, Ospedale Maggiore Policlinico Ca Granda IRCCS, Milan, Italy
    J Pediatr Gastroenterol Nutr 54:588-93. 2012
    ..The aim of the present study was to evaluate whether the lipin1 rs13412852 C>T polymorphism is associated with nonalcoholic steatohepatitis and fibrosis in pediatric Italian patients with nonalcoholic fatty liver disease (NAFLD)...
  22. pmc Pediatric non-alcoholic fatty liver disease: Preventive and therapeutic value of lifestyle intervention
    Valerio Nobili
    Liver Unit, Research Institute, , S Onofrio 4 Square, 00165 Rome, Italy
    World J Gastroenterol 15:6017-22. 2009
    ..Here, we outline the clinical course, pathogenesis and management of NAFLD in children, highlighting the preventive and therapeutic value of lifestyle intervention...