Research Topics
| G AddoloratoSummaryCountry: Italy Publications
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Publications
Suppression of alcohol delirium tremens by baclofen administration: a case reportGiovanni Addolorato
Institute of Internal Medicine, Catholic University of the Sacred Heart, Gemelli Hospital, Largo A Gemelli 8, 00168 Rome, Italy
Clin Neuropharmacol 26:258-62. 2003..Here, we report a case of DT successfully treated with baclofen. This result indicates that the efficacy of baclofen in the treatment of DT should be examined in future clinical trials...
Baclofen use in the treatment of alcohol delirium tremensLorenzo Leggio
Arch Intern Med 165:586; author reply 587. 2005
Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled studyGiovanni Addolorato
Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
Lancet 370:1915-22. 2007..We aimed to investigate the effectiveness and safety of baclofen in achieving and maintaining alcohol abstinence in patients with liver cirrhosis...
Affective and psychiatric disorders in celiac diseaseGiovanni Addolorato
Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
Dig Dis 26:140-8. 2008..The available data suggest that screening for CD in patients with affective and/or psychiatric symptoms may be useful since these disorders could be the expression of an organic disease rather than primary psychiatric illnesses...
Rapid regression of psoriasis in a coeliac patient after gluten-free diet. A case report and review of the literatureGiovanni Addolorato
Institute of Internal Medicine, Universita Cattolica del Sacro Cuore, Rome, Italy
Digestion 68:9-12. 2003..However, at present the relationship between CD and psoriasis remains controversial since there are few and contrasting data on this topic...
Anxiety but not depression decreases in coeliac patients after one-year gluten-free diet: a longitudinal studyG Addolorato
Institute of Internal Medicine, Universita Cattolica del Sacro Cuore, Rome, Italy
Scand J Gastroenterol 36:502-6. 2001..At present, the role of a gluten-free diet (GFD) on psychological disorders is still poorly known. The aim of this study was to evaluate state and trait anxiety and depression in adult CD patients before and after 1 year of GFD...
State and trait anxiety and depression in patients affected by gastrointestinal diseases: psychometric evaluation of 1641 patients referred to an internal medicine outpatient settingG Addolorato
Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
Int J Clin Pract 62:1063-9. 2008..To evaluate state and trait form of anxiety and current depression in patients affected by gastrointestinal diseases...
Changes in body composition, substrate oxidation, and resting metabolic rate in adult celiac disease patients after a 1-y gluten-free diet treatmentE Capristo
Department of Internal Medicine, CNR Centro Fisiopatologia dello Shock, Universita Cattolica del Sacro Cuore, Rome, Italy
Am J Clin Nutr 72:76-81. 2000..The incidence of celiac disease has been on the rise in both Europe and the United States. Celiac disease patients are at high risk of undernutrition because of nutrient malabsorption...
Effect of a vegetable-protein-rich polymeric diet treatment on body composition and energy metabolism in inactive Crohn's diseaseE Capristo
Institute of Internal Medicine, Universita Cattolica del Sacro Cuore, Rome, Italy
Eur J Gastroenterol Hepatol 12:5-11. 2000....
Evaluation of effects (symptoms and palatability) after ingestion of "Gran Soleil" in healthy volunteersG Gasbarrini
Institute of Internal Medicine, Catholic University, Rome, Italy
J Biol Regul Homeost Agents 22:201-5. 2008..In conclusion, it is possible to suppose that a product with a good palatability, able to support and maintain a good digestive condition, derives from the mixture of digestive herbs, citrus juices, liquor and other ingredients...
Baclofen: a new drug for the treatment of alcohol dependenceG Addolorato
Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
Int J Clin Pract 60:1003-8. 2006..The efficacy of the drug in the management of both alcohol withdrawal syndrome and relapse prevention should entail a vastly simplified pharmacotherapy of alcohol dependence...
A new HPLC method for the direct analysis of triglycerides of dicarboxylic acids in biological samplesE Capristo
Istituto di Medicina Interna e Geriatria, Universita Cattolica S Cuore, Largo A Gemelli, 8 00168, Rome, Italy
Clin Chim Acta 289:11-21. 1999....
Cutaneous manifestations in celiac diseaseL Abenavoli
Institute of Internal Medicine, Catholic University, L.go Gemelli 8, 00168 Rome, Italy
World J Gastroenterol 12:843-52. 2006..The opportunity to evaluate the possible presence of CD in patients affected by skin disorders is discussed...
Marked decrease of serum Ca 125 levels after Denver shunt placement in a patient with cirrhosis and refractory ascitesL Leggio
Institute of Internal Medicine, Catholic University of Rome, Universita' Cattolica del Sacro Cuore, Largo A. Gemelli 8, 00168 Rome, Italy
Dig Dis Sci 51:1644-6. 2006
Psychological support counselling improves gluten-free diet compliance in coeliac patients with affective disordersG Addolorato
Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
Aliment Pharmacol Ther 20:777-82. 2004..Anxiety and depression are common features of coeliac disease. Depression is cause of non-compliance to treatment in chronic illness...
Hypokalemic nephropathy in an adult patient with partial empty sella: a classic Bartter's syndrome, a Gitelman's syndrome or both?G Addolorato
Department of Internal Medicine, Catholic University of Rome, Rome, Italy
Panminerva Med 48:137-42. 2006....
Wilson's disease: clinical, genetic and pharmacological findingsL Leggio
Institute of Internal Medicine, Catholic University of Rome, Italy
Int J Immunopathol Pharmacol 18:7-14. 2005..However the most appropriate therapy, including OLT, remains controversial in WD and further studies are needed especially in order to differentiate the possibility of specific therapies for different WD phenotypes...
Lymphoepithelioma-like carcinoma of the skinS Cavalieri
Institute of Dermatology, Catholic University of the Sacred Heart, Rome, Italy
Int J Immunopathol Pharmacol 20:851-4. 2007..Lymphoepithelioma-like carcinoma of the skin is a malignant neoplasm which tends to relapse locally and has a moderate tendency to metastatize...
Serum leptin levels in post-hepatitis liver cirrhosisA V Greco
Istituto di Medicina Interna e Geriatria, Catholic University, Rome, Italy
J Hepatol 33:38-42. 2000..The behaviour of serum leptin in patients with different Child-Pugh score, post-hepatitis liver cirrhosis and insulin sensitivity has therefore been investigated and compared with that in alcoholic Child C patients...
Gamma-hydroxybutyric acid (GHB) in the treatment of alcohol withdrawal syndrome: a randomized comparative study versus benzodiazepineG Addolorato
Institute of Internal Medicine, Universita Cattolica del Sacro Cuore, Rome, Italy
Alcohol Clin Exp Res 23:1596-604. 1999..The aim of the present randomized, controlled, single-blind study was to evaluate the efficacy and safety of GHB compared with diazepam in the treatment of AWS...
Metadoxine in the treatment of acute and chronic alcoholism: a reviewG Addolorato
Institute of Internal Medicine, Catholic University of Rome, Italy
Int J Immunopathol Pharmacol 16:207-14. 2003..In this review the preclinical and clinical results obtained using metadoxine in acute and chronic alcohol intoxication are reported...
Anhedonia and substance-related symptoms in detoxified substance-dependent subjects: a correlation studyL Janiri
Institute of Psychiatry and Psychology, Treatment Unit for Alcoholism and Multiple Drug Abuse, Catholic University, Rome, Italy
Neuropsychobiology 52:37-44. 2005..In conclusion, we found interrelations between hedonic capability, craving and protracted withdrawal, particularly in opiate-dependent subjects. The strongest association occurred between hedonic capability and craving...
Evaluation of symptoms and palatability in healthy volunteers after ingestion of an iced dessert by using different flavoursA Gallo
Institute of Internal Medicine, Catholic University, Rome
J Biol Regul Homeost Agents 23:127-31. 2009....
Neuroendocrine and psychological assessment in a guinness 10 days scuba diveL Revelli
Department of Endocrine Surgery, Catholic University of Rome, Rome, Italy
Int J Sports Med 28:848-52. 2007..No subject discontinued the diving due to occurred psychological disorders or systemic events. The present report shows that the long-term diving permanence is possible, at least in well trained scuba divers...
Celiac disease in the 21st century: issues of under- and over-diagnosisG Gasbarrini
Department of Internal Medicine, Catholic University of Rome, Rome, Italy
Int J Immunopathol Pharmacol 22:1-7. 2009....
Celiac disease and skin disordersLorenzo Leggio
Pediatr Dermatol 22:376-7. 2005
The GABA(B) receptor agonists baclofen and CGP 44532 prevent acquisition of alcohol drinking behaviour in alcohol-preferring ratsGiancarlo Colombo
C.N.R. Institute of Neurogenetics and Neuropharmacology, Cagliari, Italy
Alcohol Alcohol 37:499-503. 2002....
Rapid suppression of alcohol withdrawal syndrome by baclofenGiovanni Addolorato
Institute of Internal Medicine, , Rome, Italy
Am J Med 112:226-9. 2002
Celiac diseaseAntonio Mirijello
N Engl J Med 358:747; author reply 748-9. 2008
Social phobia in coeliac diseaseGiovanni Addolorato
Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
Scand J Gastroenterol 43:410-5. 2008..Although social phobia is included among the anxiety disorders, its presence in CD has never been investigated. The aim of the present study was to evaluate social phobia in CD patients...
Subclinical neurological abnormalities in patients with celiac disease: are they associated by brain hypoperfusion?Ludovico Abenavoli
J Pediatr Gastroenterol Nutr 46:470. 2008
Role of GABA(B) receptor in alcohol dependence: reducing effect of baclofen on alcohol intake and alcohol motivational properties in rats and amelioration of alcohol withdrawal syndrome and alcohol craving in human alcoholicsGiancarlo Colombo
C N R Institute of Neuroscience, University of Cagliari, Viale Diaz, 182, I 09126 Cagliari, Italy
Neurotox Res 6:403-14. 2004..In both clinical studies, baclofen was well tolerated with minimal side effects. These results suggest that baclofen may represent a potentially effective medication in the treatment of alcohol-dependent patients...
Renin and aldosterone but not the natriuretic peptide correlate with obsessive craving in medium-term abstinent alcohol-dependent patients: a longitudinal studyLorenzo Leggio
Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
Alcohol 42:375-81. 2008..In conclusion, the renin-aldosterone axis could play a role in craving in medium-term abstinent patients and thereby leading to the hypothesis that alcohol craving could be influenced by the fluid volume intake...
Coeliac disease and hearing loss: preliminary data on a new possible associationLorenzo Leggio
Institutes of Internal Medicine, Catholic University of Rome, Rome, Italy
Scand J Gastroenterol 42:1209-13. 2007..At present, no data are available on the presence of hearing loss disorder in coeliac patients. The aim of the present study was to investigate the prevalence of hearing loss in coeliac patients compared with that in healthy controls...
[The skin as a mirror of small intestine]Ludovico Abenavoli
Istituto di Medicina Interna, Universita Cattolica del Sacro Cuore, Roma
Recenti Prog Med 98:339-46. 2007..The importance of these associations leads to conclude that skin is the "mirror" of the small intestine, and that remembering it can be necessary for specialist and generalist in their clinical practice...
Baclofen suppresses alcohol intake and craving for alcohol in a schizophrenic alcohol-dependent patient: a case reportRoberta Agabio
J Clin Psychopharmacol 27:319-20. 2007
Neurologic disorders in patients with celiac disease: are they mediated by brain perfusion changes?Ludovico Abenavoli
Pediatrics 114:1734; author reply 1734. 2004
Baclofen for outpatient treatment of alcohol withdrawal syndromeGiovanni Addolorato
J Fam Pract 54:24. 2005
Regional cerebral hypoperfusion in patients with celiac diseaseGiovanni Addolorato
Institute of Internal Medicine, Catholic University, Rome, Italy
Am J Med 116:312-7. 2004..Because of a case report that cerebral hypoperfusion in a celiac patient resolved after a gluten-free diet, we studied brain perfusion changes in untreated celiac patients, treated celiac patients, and healthy controls...
Tolerance to baclofen's sedative effect in alcohol-addicted patients: no dissipation after a period of abstinenceGiovanni Addolorato
Psychopharmacology (Berl) 178:351-2. 2005
Psychological support counseling: a new strategy to increase gluten-free diet compliance in celiac patientsLorenzo Leggio
Am J Gastroenterol 100:1424-5. 2005
Baclofen-induced reduction of alcohol reinforcement in alcohol-preferring ratsPaola Maccioni
Bernard B. Brodie Department of Neuroscience, University of Cagliari, Viale Diaz 182, I-09126 Cagliari, Italy
Alcohol 36:161-8. 2005..These data are also in agreement with the results of recent preliminary clinical studies suggesting that baclofen may have therapeutic efficacy in the treatment of alcohol dependence...
Baclofen in the treatment of alcohol withdrawal syndrome: a comparative study vs diazepamGiovanni Addolorato
Institute of Internal Medicine, Catholic University of Rome, Rome, Italy
Am J Med 119:276.e13-8. 2006..Accordingly, the present study was designed to compare efficacy, tolerability and safety of baclofen versus diazepam in the treatment of AWS...
Reduced plasma ghrelin concentration in celiac disease after gluten-free diet treatmentEsmeralda Capristo
Institute of Internal Medicine, Metabolic Unit, Catholic University, Rome, Italy
Scand J Gastroenterol 40:430-6. 2005....
Association between migraine and Celiac disease: results from a preliminary case-control and therapeutic studyMaurizio Gabrielli
Department of Internal Medicine, Catholic University of the Sacred Heart, Gemelli Hospital, Rome, Italy
Am J Gastroenterol 98:625-9. 2003..CONCLUSIONS: Our results suggest that a significant proportion of patients with migraine may have CD, and that a gluten free diet may lead to a improvement in the migraine in these patients...
Baclofen efficacy in reducing alcohol craving and intake: a preliminary double-blind randomized controlled studyGiovanni Addolorato
Institute of Internal Medicine and Institute of Psychiatry, Catholic University of Rome, Rome, Italy
Alcohol Alcohol 37:504-8. 2002....
