Research Topics
Species | Ofer YizharSummaryAffiliation: Weizmann Institute of Science Country: Israel Publications
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Detail Information
Publications
Optogenetic insights into social behavior functionOfer Yizhar
Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel
Biol Psychiatry 71:1075-80. 2012....
Neocortical excitation/inhibition balance in information processing and social dysfunctionOfer Yizhar
Department of Bioengineering, Stanford University, Stanford, California, USA
Nature 477:171-8. 2011..These results provide support for the elevated cellular E/I balance hypothesis of severe neuropsychiatric disease-related symptoms...
Ultrafast optogenetic controlLisa A Gunaydin
Department of Bioengineering, Stanford University, Stanford, California, USA
Nat Neurosci 13:387-92. 2010....
A new mode of corticothalamic transmission revealed in the Gria4(-/-) model of absence epilepsyJeanne T Paz
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA
Nat Neurosci 14:1167-73. 2011..This mode could be active under other circumstances, representing a previously unknown channel of cortico-thalamo-cortical information processing...
Optogenetics in neural systemsOfer Yizhar
Department of Bioengineering, Stanford University, Stanford, CA 94305, USA
Neuron 71:9-34. 2011..Here we provide a primer on the application of optogenetics in neuroscience, focusing on the single-component tools and highlighting important problems, challenges, and technical considerations...
Two-photon optogenetic toolbox for fast inhibition, excitation and bistable modulationRohit Prakash
Department of Bioengineering, Stanford University, Stanford, California, USA
Nat Methods 9:1171-9. 2012..Together these advances may help enable broad adoption of integrated optogenetic and TPLSMtechnologies across experimental fields and systems...
Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsinsJoanna Mattis
Department of Bioengineering, Stanford University, Stanford, California, USA
Nat Methods 9:159-72. 2012....
Parvalbumin neurons and gamma rhythms enhance cortical circuit performanceVikaas S Sohal
Department of Bioengineering, Stanford University, Stanford, California 94305, USA
Nature 459:698-702. 2009....
Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcementIlana B Witten
Department of Bioengineering, Stanford University, Stanford, CA 94305, USA
Neuron 72:721-33. 2011..These studies complement existing targeting approaches by extending the generalizability of optogenetics to traditionally non-genetically-tractable but vital animal models...
Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteriFeng Zhang
Department of Bioengineering and Psychiatry, W083 Clark Center, 318 Campus Drive, Stanford University, Stanford, California 94305, USA
Nat Neurosci 11:631-3. 2008..These results demonstrate fast photostimulation with yellow light, thereby defining a functionally distinct third category of microbial rhodopsin proteins...
Friends and foes in synaptic transmission: the role of tomosyn in vesicle primingUri Ashery
Department of Neurobiology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel
Trends Neurosci 32:275-82. 2009..We also present possible molecular scenarios for vesicle priming and the involvement of tomosyn in these processes...
An optogenetic toolbox designed for primatesIlka Diester
Department of Bioengineering, Stanford University, Stanford, California, USA
Nat Neurosci 14:387-97. 2011..We present a set of optogenetic tools designed for optogenetic experiments in the non-human primate brain...
Tuning arousal with optogenetic modulation of locus coeruleus neuronsMATTHEW E CARTER
Neurosciences Program, Stanford University, Stanford, California, USA
Nat Neurosci 13:1526-33. 2010..These results suggest that the locus coeruleus is finely tuned to regulate organismal arousal and that bursts of noradrenergic overexcitation cause behavioral attacks that resemble those seen in people with neuropsychiatric disorders...
The development and application of optogeneticsLief Fenno
Department of Bioengineering, Stanford University, Stanford, California 94305, USA
Annu Rev Neurosci 34:389-412. 2011..In this review, we outline the development of currently available single-component optogenetic tools and summarize the application of various optogenetic tools in diverse model organisms...
Modulating vesicle priming reveals that vesicle immobilization is necessary but not sufficient for fusion-competenceOfer Yizhar
Department of Neurobiology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel
PLoS ONE 3:e2694. 2008....
