Ofer Yizhar

Summary

Affiliation: Weizmann Institute of Science
Country: Israel

Publications

  1. doi request reprint Optogenetic insights into social behavior function
    Ofer Yizhar
    Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel
    Biol Psychiatry 71:1075-80. 2012
  2. doi request reprint Neocortical excitation/inhibition balance in information processing and social dysfunction
    Ofer Yizhar
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nature 477:171-8. 2011
  3. doi request reprint Ultrafast optogenetic control
    Lisa A Gunaydin
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Neurosci 13:387-92. 2010
  4. pmc A new mode of corticothalamic transmission revealed in the Gria4(-/-) model of absence epilepsy
    Jeanne T Paz
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA
    Nat Neurosci 14:1167-73. 2011
  5. doi request reprint Optogenetics in neural systems
    Ofer Yizhar
    Department of Bioengineering, Stanford University, Stanford, CA 94305, USA
    Neuron 71:9-34. 2011
  6. ncbi request reprint Two-photon optogenetic toolbox for fast inhibition, excitation and bistable modulation
    Rohit Prakash
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Methods 9:1171-9. 2012
  7. doi request reprint Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins
    Joanna Mattis
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Methods 9:159-72. 2012
  8. pmc Neuron-specific expression of tomosyn1 in the mouse hippocampal dentate gyrus impairs spatial learning and memory
    Boaz Barak
    Department of Neurobiology, Life Sciences Faculty, Tel Aviv University, 69978 Tel Aviv, Israel
    Neuromolecular Med 15:351-63. 2013
  9. doi request reprint Parvalbumin neurons and gamma rhythms enhance cortical circuit performance
    Vikaas S Sohal
    Department of Bioengineering, Stanford University, Stanford, California 94305, USA
    Nature 459:698-702. 2009
  10. pmc Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement
    Ilana B Witten
    Department of Bioengineering, Stanford University, Stanford, CA 94305, USA
    Neuron 72:721-33. 2011

Collaborators

Detail Information

Publications18

  1. doi request reprint Optogenetic insights into social behavior function
    Ofer Yizhar
    Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel
    Biol Psychiatry 71:1075-80. 2012
    ....
  2. doi request reprint Neocortical excitation/inhibition balance in information processing and social dysfunction
    Ofer Yizhar
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nature 477:171-8. 2011
    ..These results provide support for the elevated cellular E/I balance hypothesis of severe neuropsychiatric disease-related symptoms...
  3. doi request reprint Ultrafast optogenetic control
    Lisa A Gunaydin
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Neurosci 13:387-92. 2010
    ....
  4. pmc A new mode of corticothalamic transmission revealed in the Gria4(-/-) model of absence epilepsy
    Jeanne T Paz
    Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA
    Nat Neurosci 14:1167-73. 2011
    ..This mode could be active under other circumstances, representing a previously unknown channel of cortico-thalamo-cortical information processing...
  5. doi request reprint Optogenetics in neural systems
    Ofer Yizhar
    Department of Bioengineering, Stanford University, Stanford, CA 94305, USA
    Neuron 71:9-34. 2011
    ..Here we provide a primer on the application of optogenetics in neuroscience, focusing on the single-component tools and highlighting important problems, challenges, and technical considerations...
  6. ncbi request reprint Two-photon optogenetic toolbox for fast inhibition, excitation and bistable modulation
    Rohit Prakash
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Methods 9:1171-9. 2012
    ..Together these advances may help enable broad adoption of integrated optogenetic and TPLSMtechnologies across experimental fields and systems...
  7. doi request reprint Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins
    Joanna Mattis
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Methods 9:159-72. 2012
    ....
  8. pmc Neuron-specific expression of tomosyn1 in the mouse hippocampal dentate gyrus impairs spatial learning and memory
    Boaz Barak
    Department of Neurobiology, Life Sciences Faculty, Tel Aviv University, 69978 Tel Aviv, Israel
    Neuromolecular Med 15:351-63. 2013
    ..Moreover, it provides new insight regarding the role of the hippocampal dentate gyrus and mossy fiber-CA3 synapses in swimming strategy preference, and in learning and memory...
  9. doi request reprint Parvalbumin neurons and gamma rhythms enhance cortical circuit performance
    Vikaas S Sohal
    Department of Bioengineering, Stanford University, Stanford, California 94305, USA
    Nature 459:698-702. 2009
    ....
  10. pmc Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement
    Ilana B Witten
    Department of Bioengineering, Stanford University, Stanford, CA 94305, USA
    Neuron 72:721-33. 2011
    ..These studies complement existing targeting approaches by extending the generalizability of optogenetics to traditionally non-genetically-tractable but vital animal models...
  11. doi request reprint Optopatcher--an electrode holder for simultaneous intracellular patch-clamp recording and optical manipulation
    Yonatan Katz
    Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel
    J Neurosci Methods 214:113-7. 2013
    ..We demonstrate the utility of the optopatcher by recording LFP and intracellular responses to light stimulation...
  12. pmc Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri
    Feng Zhang
    Department of Bioengineering and Psychiatry, W083 Clark Center, 318 Campus Drive, Stanford University, Stanford, California 94305, USA
    Nat Neurosci 11:631-3. 2008
    ..These results demonstrate fast photostimulation with yellow light, thereby defining a functionally distinct third category of microbial rhodopsin proteins...
  13. pmc Friends and foes in synaptic transmission: the role of tomosyn in vesicle priming
    Uri Ashery
    Department of Neurobiology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel
    Trends Neurosci 32:275-82. 2009
    ..We also present possible molecular scenarios for vesicle priming and the involvement of tomosyn in these processes...
  14. doi request reprint The development and application of optogenetics
    Lief Fenno
    Department of Bioengineering, Stanford University, Stanford, California 94305, USA
    Annu Rev Neurosci 34:389-412. 2011
    ..In this review, we outline the development of currently available single-component optogenetic tools and summarize the application of various optogenetic tools in diverse model organisms...
  15. pmc An optogenetic toolbox designed for primates
    Ilka Diester
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Nat Neurosci 14:387-97. 2011
    ..We present a set of optogenetic tools designed for optogenetic experiments in the non-human primate brain...
  16. pmc Tuning arousal with optogenetic modulation of locus coeruleus neurons
    MATTHEW E CARTER
    Neurosciences Program, Stanford University, Stanford, California, USA
    Nat Neurosci 13:1526-33. 2010
    ..These results suggest that the locus coeruleus is finely tuned to regulate organismal arousal and that bursts of noradrenergic overexcitation cause behavioral attacks that resemble those seen in people with neuropsychiatric disorders...
  17. pmc GABAergic projection neurons route selective olfactory inputs to specific higher-order neurons
    Liang Liang
    Department of Biology and Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA Department of Applied Physics, Stanford University, Stanford, CA 94305, USA
    Neuron 79:917-31. 2013
    ..The parallel inhibition motif may provide specificity in inhibition to funnel specific olfactory information, such as food and pheromone, into distinct downstream circuits. ..
  18. pmc Modulating vesicle priming reveals that vesicle immobilization is necessary but not sufficient for fusion-competence
    Ofer Yizhar
    Department of Neurobiology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel
    PLoS ONE 3:e2694. 2008
    ....