Joel Stavans

Summary

Affiliation: Weizmann Institute of Science
Country: Israel

Publications

  1. pmc Noise in timing and precision of gene activities in a genetic cascade
    Amnon Amir
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel
    Mol Syst Biol 3:71. 2007
  2. pmc High fidelity of RecA-catalyzed recombination: a watchdog of genetic diversity
    Dror Sagi
    Department of Physics of Complex Systems, The Weizmann Institute of Science, Rehovot 76100, Israel
    Nucleic Acids Res 34:5021-31. 2006
  3. pmc Caught in the act: the lifetime of synaptic intermediates during the search for homology on DNA
    Adam Mani
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel
    Nucleic Acids Res 38:2036-43. 2010
  4. pmc Effects of post-transcriptional regulation on phenotypic noise in Escherichia coli
    Rinat Arbel-Goren
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel
    Nucleic Acids Res 41:4825-34. 2013
  5. pmc Direct observation of RuvAB-catalyzed branch migration of single Holliday junctions
    Roee Amit
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel
    Proc Natl Acad Sci U S A 101:11605-10. 2004
  6. pmc Precise temporal modulation in the response of the SOS DNA repair network in individual bacteria
    Nir Friedman
    Department of Physics of Complex Systems, The Weizmann Institute of Science, Rehovot, Israel
    PLoS Biol 3:e238. 2005
  7. ncbi request reprint Modulation of DNA conformations through the formation of alternative high-order HU-DNA complexes
    Dror Sagi
    Department of Physics of Complex Systems, The Weizmann Institute of Science, Rehovot 76100, Israel
    J Mol Biol 341:419-28. 2004
  8. ncbi request reprint Damped oscillations in the adaptive response of the iron homeostasis network of E. coli
    Amnon Amir
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel
    Mol Microbiol 76:428-36. 2010
  9. pmc Location of the unique integration site on an Escherichia coli chromosome by bacteriophage lambda DNA in vivo
    Asaf Tal
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel and
    Proc Natl Acad Sci U S A 111:7308-12. 2014
  10. doi request reprint Cancer-associated mutations in BRC domains of BRCA2 affect homologous recombination induced by Rad51
    Asaf Tal
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel
    J Mol Biol 393:1007-12. 2009

Collaborators

Detail Information

Publications13

  1. pmc Noise in timing and precision of gene activities in a genetic cascade
    Amnon Amir
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel
    Mol Syst Biol 3:71. 2007
    ..Evidence for the independence of regulatory modules in the network is presented...
  2. pmc High fidelity of RecA-catalyzed recombination: a watchdog of genetic diversity
    Dror Sagi
    Department of Physics of Complex Systems, The Weizmann Institute of Science, Rehovot 76100, Israel
    Nucleic Acids Res 34:5021-31. 2006
    ..The exquisite sensitivity to mismatches and the directionality in the exchange process support a mechanism for homology recognition that can be modeled as a kinetic proofreading cascade...
  3. pmc Caught in the act: the lifetime of synaptic intermediates during the search for homology on DNA
    Adam Mani
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel
    Nucleic Acids Res 38:2036-43. 2010
    ..These results suggest the need for facilitated homology search mechanisms to locate homology successfully within the timescales observed in vivo...
  4. pmc Effects of post-transcriptional regulation on phenotypic noise in Escherichia coli
    Rinat Arbel-Goren
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel
    Nucleic Acids Res 41:4825-34. 2013
    ..Stochastic simulations reproduce qualitatively key features of our observations and show that a feed-forward loop formed by transcriptional extrinsic noise, an sRNA and its target genes exhibits strong noise filtration capabilities...
  5. pmc Direct observation of RuvAB-catalyzed branch migration of single Holliday junctions
    Roee Amit
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel
    Proc Natl Acad Sci U S A 101:11605-10. 2004
    ..The apparent processivity of branch migration between pauses of inactivity is approximately 7,000 bp. Branch migration persists against opposing forces up to 23 pN...
  6. pmc Precise temporal modulation in the response of the SOS DNA repair network in individual bacteria
    Nir Friedman
    Department of Physics of Complex Systems, The Weizmann Institute of Science, Rehovot, Israel
    PLoS Biol 3:e238. 2005
    ....
  7. ncbi request reprint Modulation of DNA conformations through the formation of alternative high-order HU-DNA complexes
    Dror Sagi
    Department of Physics of Complex Systems, The Weizmann Institute of Science, Rehovot 76100, Israel
    J Mol Biol 341:419-28. 2004
    ..The abrogation of these nucleosome-like structures for high HU to DNA ratios suggests a unique role for HU in the dynamic modulation of bacterial nucleoid structure...
  8. ncbi request reprint Damped oscillations in the adaptive response of the iron homeostasis network of E. coli
    Amnon Amir
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel
    Mol Microbiol 76:428-36. 2010
    ..Taken together, our results shed light on the control of iron metabolism in bacteria and suggest that the oscillations represent a compromise between the requirements of stability and speed of response...
  9. pmc Location of the unique integration site on an Escherichia coli chromosome by bacteriophage lambda DNA in vivo
    Asaf Tal
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel and
    Proc Natl Acad Sci U S A 111:7308-12. 2014
    ..This novel search mechanism is yet another example of the exquisite coevolution of λ with its host. ..
  10. doi request reprint Cancer-associated mutations in BRC domains of BRCA2 affect homologous recombination induced by Rad51
    Asaf Tal
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel
    J Mol Biol 393:1007-12. 2009
    ..We suggest that mutations at sites crucial for the association between Rad51 and BRC domains impair the ability of BRCA2 to recruit Rad51 to dsDNA breaks, hampering recombinational repair...
  11. ncbi request reprint DNA-protein interactions and bacterial chromosome architecture
    Joel Stavans
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel
    Phys Biol 3:R1-10. 2006
    ..We review these recent developments with emphasis on the multifaceted roles that DNA-protein interactions play...
  12. doi request reprint Phenotypic noise: effects of post-transcriptional regulatory processes affecting mRNA
    Rinat Arbel-Goren
    Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel
    Wiley Interdiscip Rev RNA 5:197-207. 2014
    ....
  13. pmc Increased bending rigidity of single DNA molecules by H-NS, a temperature and osmolarity sensor
    Roee Amit
    Department of Physics of Complex Systems, The Weizmann Institute of Science, Rehovot 76100, Israel
    Biophys J 84:2467-73. 2003
    ..Thus, we propose that H-NS plays a unique structural role, different from that of HU and IHF, and functions as one of the environmental sensors of the cell...