Research Topics
| H MarkramSummaryAffiliation: Weizmann Institute of Science Country: Israel Publications
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Detail Information
Publications
Regulation of synaptic efficacy by coincidence of postsynaptic APs and EPSPsH Markram
Max Planck Institut fur medizinische Forschung, Abteilung Zellphysiologie, Jahnstrasse 29, D 69120 Heidelberg, Germany
Science 275:213-5. 1997..These observations suggest that APs propagating back into dendrites serve to modify single active synaptic connections, depending on the pattern of electrical activity in the pre- and postsynaptic neurons...
Information processing with frequency-dependent synaptic connectionsH Markram
Department of Neurobiology, The Weizmann Institute for Science, Rehovot, 76100, Israel
Neurobiol Learn Mem 70:101-12. 1998....
Potential for multiple mechanisms, phenomena and algorithms for synaptic plasticity at single synapsesH Markram
Department of Neurobiology, The Weizmann Institute for Science, Rehovot, Israel
Neuropharmacology 37:489-500. 1998..This may indicate that the various mechanisms, phenomena and algorithms are interlinked in a 'synaptic plasticity code'...
Competitive calcium binding: implications for dendritic calcium signalingH Markram
Department of Neurobiology, Weizmann Institute, Rehovot, Israel
J Comput Neurosci 5:331-48. 1998..Nonequilibrium calcium dynamics is proposed as a potential mechanism for differential and conditional activation of intradendritic targets...
Differential signaling via the same axon of neocortical pyramidal neuronsH Markram
Department of Neurobiology, The Weizmann Institute for Science, Rehovot, 76100, Israel
Proc Natl Acad Sci U S A 95:5323-8. 1998..It is therefore proposed that differential signaling is a key mechanism in neocortical information processing, which can be regulated by selective synaptic modifications...
A network of tufted layer 5 pyramidal neuronsH Markram
Department of Neurobiology, Weizmann Institute for Science, Rehovot, Israel
Cereb Cortex 7:523-33. 1997..These data may be important to understand the dynamics of electrical activity within the network...
Physiology and anatomy of synaptic connections between thick tufted pyramidal neurones in the developing rat neocortexH Markram
Max Planck Institut fur medizinische Forschung, Abteilung Zellphysiologie, Germany
J Physiol 500:409-40. 1997..neurones, which have their synaptic contacts preferentially located on basal and apical oblique dendrites, was due to differences in transmitter release probability of the projecting neurones and, to a lesser extent, to differenc..
Synchrony generation in recurrent networks with frequency-dependent synapsesM Tsodyks
Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel
J Neurosci 20:RC50. 2000....
An algorithm for modifying neurotransmitter release probability based on pre- and postsynaptic spike timingW Senn
Department of Neurobiology, Weizmann Institute, Rehovot, Israel
Neural Comput 13:35-67. 2001..We conclude that the proposed spike-based synaptic learning algorithm provides a general framework for regulating neurotransmitter release probability...
The neural code between neocortical pyramidal neurons depends on neurotransmitter release probabilityM V Tsodyks
Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel
Proc Natl Acad Sci U S A 94:719-23. 1997..We conclude that by setting the rate of synaptic depression, release probability is an important factor in determining the neural code...
Dendritic and somatic glutamate receptor channels in rat cerebellar Purkinje cellsM Hausser
Abteilung Zellphysiologie, Max Planck Institut fur medizinische Forschung, Heidelberg, Germany
J Physiol 501:77-95. 1997..A kinetic model was constructed which faithfully reproduces the gating characteristics of the GluR channels...
Compartmental models of rat cerebellar Purkinje cells based on simultaneous somatic and dendritic patch-clamp recordingsA Roth
Abteilung Zellphysiologie, , Jahnstrasse 29, 69120 Heidelberg, Germany
J Physiol 535:445-72. 2001..6. The passive electrotonic structure of Purkinje cells is unusual in that the steady-state architecture is very compact, while voltage transients such as synaptic potentials and action potentials are heavily filtered...
Dynamics of population rate codes in ensembles of neocortical neuronsG Silberberg
Department of Neurobiology, The Weizmann Institute of Science, Rehovot, 76100, Israel
J Neurophysiol 91:704-9. 2004..In contrast, the encoding of signals in the mean current is subject to low-pass filtering...
Nonlinear anisotropic diffusion filtering of three-dimensional image data from two-photon microscopyPhilip J Broser
Max Planck Institut fur medizinische Forschung, Abteilung Zellphysiologie, Jahnstr 29, D 69120, Heidelberg, Germany
J Biomed Opt 9:1253-64. 2004..The filter is a valuable general tool for smoothing cellular processes and is well suited for preparing data for subsequent image segmentation and neuron reconstruction...
