Mia Levite

Summary

Affiliation: Weizmann Institute of Science
Country: Israel

Publications

  1. ncbi Extracellular K(+) and opening of voltage-gated potassium channels activate T cell integrin function: physical and functional association between Kv1.3 channels and beta1 integrins
    M Levite
    Department of Immunology, The Weizmann Institute of Science, Rehovot 76100, Israel
    J Exp Med 191:1167-76. 2000
  2. ncbi Nerve-driven immunity. The direct effects of neurotransmitters on T-cell function
    M Levite
    Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel
    Ann N Y Acad Sci 917:307-21. 2000
  3. ncbi Dopamine interacts directly with its D3 and D2 receptors on normal human T cells, and activates beta1 integrin function
    M Levite
    The Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Immunol 31:3504-12. 2001
  4. ncbi Nerve-driven immunity: neuropeptides regulate cytokine secretion of T cells and intestinal epithelial cells in a direct, powerful and contextual manner
    M Levite
    Department of Immunology, The Weizmann Institute of Science, and the The Sackler Faculty of Medicine, Tel Aviv University, Israel
    Ann Oncol 12:S19-25. 2001
  5. ncbi Autoantibodies to glutamate receptors can damage the brain in epilepsy, systemic lupus erythematosus and encephalitis
    Mia Levite
    School of Behavioral Sciences, Academic College of TLV Yaffo, Israel The Weizmann Institue of Science, Rehovot 76100, Israel
    Expert Rev Neurother 8:1141-60. 2008
  6. ncbi TCR activation eliminates glutamate receptor GluR3 from the cell surface of normal human T cells, via an autocrine/paracrine granzyme B-mediated proteolytic cleavage
    Yonatan Ganor
    Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel
    J Immunol 178:683-92. 2007
  7. ncbi Autoimmune epilepsy: distinct subpopulations of epilepsy patients harbor serum autoantibodies to either glutamate/AMPA receptor GluR3, glutamate/NMDA receptor subunit NR2A or double-stranded DNA
    Yonatan Ganor
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
    Epilepsy Res 65:11-22. 2005
  8. ncbi Monozygotic twins discordant for epilepsy differ in the levels of potentially pathogenic autoantibodies and cytokines
    Yonatan Ganor
    Department of Neurobiology, The Weizmann Institute of Science, 76100 Rehovot, Israel
    Autoimmunity 38:139-50. 2005
  9. ncbi Immunization with the glutamate receptor-derived peptide GluR3B induces neuronal death and reactive gliosis, but confers partial protection from pentylenetetrazole-induced seizures
    Yonatan Ganor
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
    Exp Neurol 195:92-102. 2005
  10. ncbi Human T cells express a functional ionotropic glutamate receptor GluR3, and glutamate by itself triggers integrin-mediated adhesion to laminin and fibronectin and chemotactic migration
    Yonatan Ganor
    Weizmann Institute of Science, Rehovot, Israel Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel
    J Immunol 170:4362-72. 2003

Collaborators

  • Vivian I Teichberg
  • M Y Chowers
  • Anthony H Futerman
  • Michal J Besser
  • Tamar Unger
  • Ronald S Goldstein
  • N Watemberg
  • Yonatan Ganor
  • Tally Lerman-Sagie
  • Barak Tziperman
  • Katayun Cohen-Kashi Malina
  • Michael Freilinger
  • Hadassa Goldberg-Stern
  • Alon Chen
  • Arbel Reis
  • Itzik Cooper
  • Igor Grinberg
  • Nili Schoenfeld
  • Ben Zion Garty
  • Yonathan Ganor
  • Dorit Lev
  • Vered Hoffer
  • Ben-Zion Garty
  • Olivier Dulac
  • Miroslav Gottlieb
  • Raya Eilam
  • Hanoch Otmy
  • Denis Verheulpen
  • Dina Amromd
  • Bruria Ben Zeev
  • Patrick Van Bogaert
  • Dori Pelled
  • Naomie Ben-Zakay
  • Yitzhak Koch
  • Shai Rahimipour
  • Nurit Ben-Aroya

Detail Information

Publications17

  1. ncbi Extracellular K(+) and opening of voltage-gated potassium channels activate T cell integrin function: physical and functional association between Kv1.3 channels and beta1 integrins
    M Levite
    Department of Immunology, The Weizmann Institute of Science, Rehovot 76100, Israel
    J Exp Med 191:1167-76. 2000
    ..e., by elevated [K(+)](o)). In addition, our results suggest that undesired T cell integrin function in a series of pathological conditions can be arrested by molecules that block the Kv1.3 channels...
  2. ncbi Nerve-driven immunity. The direct effects of neurotransmitters on T-cell function
    M Levite
    Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel
    Ann N Y Acad Sci 917:307-21. 2000
    ..As a whole, our studies suggest an important and yet unrecognized role for neurotransmitters in directly dictating or modulating numerous T-cell functions under physiological and pathological conditions...
  3. ncbi Dopamine interacts directly with its D3 and D2 receptors on normal human T cells, and activates beta1 integrin function
    M Levite
    The Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Immunol 31:3504-12. 2001
    ....
  4. ncbi Nerve-driven immunity: neuropeptides regulate cytokine secretion of T cells and intestinal epithelial cells in a direct, powerful and contextual manner
    M Levite
    Department of Immunology, The Weizmann Institute of Science, and the The Sackler Faculty of Medicine, Tel Aviv University, Israel
    Ann Oncol 12:S19-25. 2001
    ....
  5. ncbi Autoantibodies to glutamate receptors can damage the brain in epilepsy, systemic lupus erythematosus and encephalitis
    Mia Levite
    School of Behavioral Sciences, Academic College of TLV Yaffo, Israel The Weizmann Institue of Science, Rehovot 76100, Israel
    Expert Rev Neurother 8:1141-60. 2008
    ....
  6. ncbi TCR activation eliminates glutamate receptor GluR3 from the cell surface of normal human T cells, via an autocrine/paracrine granzyme B-mediated proteolytic cleavage
    Yonatan Ganor
    Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel
    J Immunol 178:683-92. 2007
    ....
  7. ncbi Autoimmune epilepsy: distinct subpopulations of epilepsy patients harbor serum autoantibodies to either glutamate/AMPA receptor GluR3, glutamate/NMDA receptor subunit NR2A or double-stranded DNA
    Yonatan Ganor
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
    Epilepsy Res 65:11-22. 2005
    ..We suggest to measure the 'autoimmune-fingerprints' of epilepsy patients for diagnostic and therapeutic purposes...
  8. ncbi Monozygotic twins discordant for epilepsy differ in the levels of potentially pathogenic autoantibodies and cytokines
    Yonatan Ganor
    Department of Neurobiology, The Weizmann Institute of Science, 76100 Rehovot, Israel
    Autoimmunity 38:139-50. 2005
    ..These findings and suggestions may be of clinical importance and call for further studies...
  9. ncbi Immunization with the glutamate receptor-derived peptide GluR3B induces neuronal death and reactive gliosis, but confers partial protection from pentylenetetrazole-induced seizures
    Yonatan Ganor
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
    Exp Neurol 195:92-102. 2005
    ..The present results could have clinical implications for epilepsy...
  10. ncbi Human T cells express a functional ionotropic glutamate receptor GluR3, and glutamate by itself triggers integrin-mediated adhesion to laminin and fibronectin and chemotactic migration
    Yonatan Ganor
    Weizmann Institute of Science, Rehovot, Israel Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel
    J Immunol 170:4362-72. 2003
    ..Thus far, GluR3 was found only on neurons and glia cells; our results reveal a novel peripheral source of this antigenic receptor...
  11. ncbi Human T-leukemia and T-lymphoma express glutamate receptor AMPA GluR3, and the neurotransmitter glutamate elevates the cancer-related matrix-metalloproteinases inducer CD147/EMMPRIN, MMP-9 secretion and engraftment of T-leukemia in vivo
    Yonatan Ganor
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot, Israel
    Leuk Lymphoma 50:985-97. 2009
    ..If so, glutamate receptors in T-cell malignancies should be blocked...
  12. ncbi Autoimmune epilepsy: some epilepsy patients harbor autoantibodies to glutamate receptors and dsDNA on both sides of the blood-brain barrier, which may kill neurons and decrease in brain fluids after hemispherotomy
    Yonatan Ganor
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot, Israel
    Clin Dev Immunol 11:241-52. 2004
    ..Since all these Ab's may be detrimental to the nervous system and/or peripheral organs, we recommend testing for their presence in epilepsy, and silencing their activity in Ab-positive patients...
  13. ncbi Dopamine by itself activates either D2, D3 or D1/D5 dopaminergic receptors in normal human T-cells and triggers the selective secretion of either IL-10, TNFalpha or both
    Michal J Besser
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot, Israel
    J Neuroimmunol 169:161-71. 2005
    ....
  14. ncbi Autoantibodies against an extracellular peptide of the GluR3 subtype of AMPA receptors activate both homomeric and heteromeric AMPA receptor channels
    Katayun Cohen-Kashi Malina
    Department of Neurobiology, The Weizmann Institute of Science, 76100 Rehovot, Israel
    Neurochem Res 31:1181-90. 2006
    ..We present some of the properties of the purified anti-GluR3B Abs and discuss the possible physiological or pathological consequences of their activation of glutamate receptors...
  15. ncbi The neuropeptides GnRH-II and GnRH-I are produced by human T cells and trigger laminin receptor gene expression, adhesion, chemotaxis and homing to specific organs
    Alon Chen
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot, Israel
    Nat Med 8:1421-6. 2002
    ....
  16. ncbi Acute intermittent porphyria, Rasmussen encephalitis, or both?
    Barak Tziperman
    Pediatric Neurology Unit, Wolfson Medical Center, Holon, Israel
    J Child Neurol 22:99-105. 2007
    ..The authors recommend testing for porphyria in cases of Rasmussen encephalitis and other intractable seizures...
  17. ncbi Autoimmune epilepsy
    Mia Levite
    Nat Immunol 3:500. 2002