Amiram Grinvald

Summary

Affiliation: Weizmann Institute of Science
Country: Israel

Publications

  1. ncbi request reprint High-resolution functional optical imaging: from the neocortex to the eye
    Amiram Grinvald
    Department of Neurobiology, The Weizmann Institute of Science, The Grodetsky Center for Research of Higher Brain Functions, Rehovot, Israel
    Ophthalmol Clin North Am 17:53-67. 2004
  2. doi request reprint Removal of spatial biological artifacts in functional maps by local similarity minimization
    Tomer Fekete
    Department of Neurobiology, The Weizmann Institute of Science, 76100 Rehovot, Israel
    J Neurosci Methods 178:31-9. 2009
  3. ncbi request reprint Compartment-resolved imaging of activity-dependent dynamics of cortical blood volume and oximetry
    Ivo Vanzetta
    Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel
    J Neurosci 25:2233-44. 2005
  4. ncbi request reprint Special report: Noninvasive multi-parameter functional optical imaging of the eye
    Darin A Nelson
    Optical Imaging, Ltd, Rehovot, Israel
    Ophthalmic Surg Lasers Imaging 36:57-66. 2005
  5. doi request reprint Functional imaging using the retinal function imager: direct imaging of blood velocity, achieving fluorescein angiography-like images without any contrast agent, qualitative oximetry, and functional metabolic signals
    David Izhaky
    Optical Imaging Ltd, Rehovot, Israel
    Jpn J Ophthalmol 53:345-51. 2009
  6. ncbi request reprint Columnar resolution of blood volume and oximetry functional maps in the behaving monkey; implications for FMRI
    Ivo Vanzetta
    Department of Neurobiology, The Weizmann Institute of Science, 76100 Rehovot, Israel
    Neuron 42:843-54. 2004
  7. doi request reprint Arousal increases the representational capacity of cortical tissue
    Tomer Fekete
    Department of Neurobiology, Weizmann Institute of Science, Rehovot, 76100, Israel
    J Comput Neurosci 27:211-27. 2009
  8. ncbi request reprint Spontaneously emerging cortical representations of visual attributes
    Tal Kenet
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
    Nature 425:954-6. 2003
  9. ncbi request reprint Imaging spatiotemporal dynamics of surround inhibition in the barrels somatosensory cortex
    Dori Derdikman
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
    J Neurosci 23:3100-5. 2003
  10. ncbi request reprint Retinotopic axis specificity and selective clustering of feedback projections from V2 to V1 in the owl monkey
    Amir Shmuel
    Department of Neurobiology, The Weizmann Institute of Science, 76100 Rehovot, Israel
    J Neurosci 25:2117-31. 2005

Collaborators

Detail Information

Publications31

  1. ncbi request reprint High-resolution functional optical imaging: from the neocortex to the eye
    Amiram Grinvald
    Department of Neurobiology, The Weizmann Institute of Science, The Grodetsky Center for Research of Higher Brain Functions, Rehovot, Israel
    Ophthalmol Clin North Am 17:53-67. 2004
    ....
  2. doi request reprint Removal of spatial biological artifacts in functional maps by local similarity minimization
    Tomer Fekete
    Department of Neurobiology, The Weizmann Institute of Science, 76100 Rehovot, Israel
    J Neurosci Methods 178:31-9. 2009
    ..Examples obtained from our imaging experiments with anaesthetized cats and behaving monkeys showed that the LSM method is both general and reproducible, and is often superior to other available procedures...
  3. ncbi request reprint Compartment-resolved imaging of activity-dependent dynamics of cortical blood volume and oximetry
    Ivo Vanzetta
    Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel
    J Neurosci 25:2233-44. 2005
    ....
  4. ncbi request reprint Special report: Noninvasive multi-parameter functional optical imaging of the eye
    Darin A Nelson
    Optical Imaging, Ltd, Rehovot, Israel
    Ophthalmic Surg Lasers Imaging 36:57-66. 2005
    ..Imaging functional changes before anatomic consequences arise holds promise as a powerful tool for early diagnosis and treatment of retinal disease...
  5. doi request reprint Functional imaging using the retinal function imager: direct imaging of blood velocity, achieving fluorescein angiography-like images without any contrast agent, qualitative oximetry, and functional metabolic signals
    David Izhaky
    Optical Imaging Ltd, Rehovot, Israel
    Jpn J Ophthalmol 53:345-51. 2009
    ..The results suggest multiple clinical applications for early diagnosis of retinal diseases and possible critical guidance of their treatment...
  6. ncbi request reprint Columnar resolution of blood volume and oximetry functional maps in the behaving monkey; implications for FMRI
    Ivo Vanzetta
    Department of Neurobiology, The Weizmann Institute of Science, 76100 Rehovot, Israel
    Neuron 42:843-54. 2004
    ..Blood volume and -flow based single-condition functional mapping at columnar level should thus be feasible, provided that the capillary response component is selectively imaged...
  7. doi request reprint Arousal increases the representational capacity of cortical tissue
    Tomer Fekete
    Department of Neurobiology, Weizmann Institute of Science, Rehovot, 76100, Israel
    J Comput Neurosci 27:211-27. 2009
    ..Moreover, the complexity of structure of activity space (that is VSDI movie space) as measured by persistent homology-a multi scale topological measure of complexity-increased with arousal as well...
  8. ncbi request reprint Spontaneously emerging cortical representations of visual attributes
    Tal Kenet
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
    Nature 425:954-6. 2003
    ..We suggest that dynamically switching cortical states could represent the brain's internal context, and therefore reflect or influence memory, perception and behaviour...
  9. ncbi request reprint Imaging spatiotemporal dynamics of surround inhibition in the barrels somatosensory cortex
    Dori Derdikman
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot 76100, Israel
    J Neurosci 23:3100-5. 2003
    ..By using new, improved VSD, the present findings shed new light on the spatial parameters of the intricate spatiotemporal cortical interplay of inhibition and excitation...
  10. ncbi request reprint Retinotopic axis specificity and selective clustering of feedback projections from V2 to V1 in the owl monkey
    Amir Shmuel
    Department of Neurobiology, The Weizmann Institute of Science, 76100 Rehovot, Israel
    J Neurosci 25:2117-31. 2005
    ..We conclude that the feedback connections from V2 to V1 might play a role in enhancing the response in V1 to collinear contour elements...
  11. pmc Imaging input and output dynamics of neocortical networks in vivo: exciting times ahead
    Amiram Grinvald
    Department of Neurobiology, The Weizmann Institute of Science, 76100 Rehovot, Israel
    Proc Natl Acad Sci U S A 102:14125-6. 2005
  12. doi request reprint Increased retinal blood flow velocity in patients with early diabetes mellitus
    Zvia Burgansky-Eliash
    Department of Ophthalmology, Edith Wolfson Medical Center, Holon, Israel
    Retina 32:112-9. 2012
    ..To compare retinal blood flow velocity in small vessels of patients with early diabetes mellitus (DM), without any morphologic changes related to diabetic retinopathy, with that in a control group...
  13. ncbi request reprint Imaging cortical correlates of illusion in early visual cortex
    Dirk Jancke
    Department of Neurobiology and the Grodetsky Center for Studies of Higher Brain Function, The Weizmann Institute of Science, 76100 Rehovot, Israel
    Nature 428:423-6. 2004
    ..These findings demonstrate the effect of spatio-temporal patterns of subthreshold synaptic potentials on cortical processing and the shaping of perception...
  14. ncbi request reprint Dynamics and constancy in cortical spatiotemporal patterns of orientation processing
    Dahlia Sharon
    Department of Neurobiology and the Center for Studies of Higher Brain Functions, Weizmann Institute of Science, Rehovot 76100, Israel
    Science 295:512-5. 2002
    ..Thus, feedforward models and recurrent models of orientation selectivity must be combined...
  15. ncbi request reprint Spatio-temporal dynamics of odor representations in the mammalian olfactory bulb
    Hartwig Spors
    The Department of Neurobiology, Weizmann Institute of Science, 76100, Rehovot, Israel
    Neuron 34:301-15. 2002
    ..Our data show that in the mammalian olfactory bulb, odor identity and concentration are represented by spatio-temporal patterns, rather than spatial patterns alone...
  16. ncbi request reprint Optical imaging combined with targeted electrical recordings, microstimulation, or tracer injections
    Amos Arieli
    Department of Neurobiology, The Weizmann Institute of Science, 76100 Rehovot, Israel
    J Neurosci Methods 116:15-28. 2002
    ..For chronic experiments, this arrangement allows the animal to be handled over a long period while fitted with a sealed cranial window of minimal volume and weight, and with negligible risk of accidental damage or infection...
  17. ncbi request reprint Dural substitute for long-term imaging of cortical activity in behaving monkeys and its clinical implications
    Amos Arieli
    The Weizmann Institute of Science, Department of Neurobiology, 76100, Rehovot, Israel
    J Neurosci Methods 114:119-33. 2002
    ....
  18. ncbi request reprint Dynamics of depolarization and hyperpolarization in the frontal cortex and saccade goal
    Eyal Seidemann
    Department of Neurobiology and the Grodetsky Center for Studies of Higher Brain Function, Weizmann Institute of Science, Rehovot 76100, Israel
    Science 295:862-5. 2002
    ..During this hyperpolarization saccades are almost exclusively ipsilateral, suggesting an important role for hyperpolarization in determining saccade goal...
  19. ncbi request reprint VSDI: a new era in functional imaging of cortical dynamics
    Amiram Grinvald
    Department of Neurobiology, The Weizmann Institute of Science, Rehovot, 76100 Israel
    Nat Rev Neurosci 5:874-85. 2004
    ..It has facilitated the exploration of fundamental mechanisms that underlie neocortical development, function and plasticity at the fundamental level of the cortical column...
  20. doi request reprint Temporally-structured acquisition of multidimensional optical imaging data facilitates visualization of elusive cortical representations in the behaving monkey
    David B Omer
    Department of Neurobiology, The Weizmann Institute of Science, 76100 Rehovot, Israel Electronic address
    Neuroimage 82:237-51. 2013
    ..This methodology can thus facilitate rapid optical imaging explorations in monkeys, rodents and other species with a versatility and speed that were not feasible before. ..
  21. pmc High-resolution wide-field imaging of perfused capillaries without the use of contrast agent
    Darin A Nelson
    Optical Imaging Ltd, Rehovot, Israel
    Clin Ophthalmol 5:1095-106. 2011
    ..Here we describe the clinical use of hemoglobin in red blood cells (RBCs) as an intrinsic motion-contrast agent in the generation of detailed noninvasive capillary-perfusion maps (nCPMs)...
  22. pmc Lateral Spread of Orientation Selectivity in V1 is Controlled by Intracortical Cooperativity
    Frederic Chavane
    Department of Neurobiology, Weizmann Institute of Science Rehovot, Israel
    Front Syst Neurosci 5:4. 2011
    ..We conclude that stimulus-induced cooperativity enhances the long-range orientation-selective spread...
  23. ncbi request reprint Neuronal assemblies: single cortical neurons are obedient members of a huge orchestra
    Amiram Grinvald
    Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel
    Biopolymers 68:422-36. 2003
    ....
  24. doi request reprint A processing work-flow for measuring erythrocytes velocity in extended vascular networks from wide field high-resolution optical imaging data
    Thomas Deneux
    Institut de Neurosciences Cognitives de la Mediterranee, UMR6193, CNRS and Aix Marseille Université, Marseille, France
    Neuroimage 59:2569-88. 2012
    ..Finally, we report, for the first time, visually-evoked RBC speed responses in an extended vascular network in awake monkey extrastriate cortex...
  25. ncbi request reprint Long-term voltage-sensitive dye imaging reveals cortical dynamics in behaving monkeys
    Hamutal Slovin
    Department of Neurobiology and Grodetsky Center for Studies of Higher Brain Function, The Weizmann Institute of Science, 76100 Rehovot, Israel
    J Neurophysiol 88:3421-38. 2002
    ..We also found that a saccade to a small stimulus was followed by direct transient activation of a cortical region in areas of V1 and V2, located retinotopically within the saccadic trajectory...
  26. ncbi request reprint Cortical response field dynamics in cat visual cortex
    Dahlia Sharon
    Neurobiology Department, Weizmann Institute of Science, Rehovot 76100, Israel
    Cereb Cortex 17:2866-77. 2007
    ....
  27. ncbi request reprint Independent component analysis of high-resolution imaging data identifies distinct functional domains
    Jürgen Reidl
    WIN Group of Olfactory Dynamics, Heidelberger Akademie der Wissenschaften, Germany
    Neuroimage 34:94-108. 2007
    ..sICA following PCA is therefore a powerful technique for data compression, unbiased analysis and dissection of imaging data of population activity, collected with high spatial and temporal resolution...
  28. ncbi request reprint Reply to Carreira-Perpiñán and Goodhill. Are visual cortex maps optimized for coverage?
    Nicholas V Swindale
    Department of Ophthalmology, University of British Columbia, Vancouver, B C, V5Z 3N9
    Neural Comput 14:2053-6. 2002
  29. ncbi request reprint The spatial pattern of response magnitude and selectivity for orientation and direction in cat visual cortex
    Nicholas V Swindale
    Department of Ophthalmology and Visual Sciences, University of British Columbia, 2550 Willow Street, Vancouver, BC, Canada V5Z 3N9
    Cereb Cortex 13:225-38. 2003
    ..Orientation and direction preference angles are always closely orthogonal. Reversals in direction preference form lines that originate precisely in orientation singularities...
  30. ncbi request reprint Spatiotemporal dynamics of sensory responses in layer 2/3 of rat barrel cortex measured in vivo by voltage-sensitive dye imaging combined with whole-cell voltage recordings and neuron reconstructions
    Carl C H Petersen
    Department of Cell Physiology, Max Planck Institute for Medical Research, Heidelberg D 69120, Germany
    J Neurosci 23:1298-309. 2003
    ....
  31. pmc Interaction of sensory responses with spontaneous depolarization in layer 2/3 barrel cortex
    Carl C H Petersen
    Department of Cell Physiology, Max Planck Institute for Medical Research, Jahnstrasse 29, Heidelberg D 69120, Germany
    Proc Natl Acad Sci U S A 100:13638-43. 2003
    ..The ongoing spontaneous activity thus regulates the amplitude and the time-dependent spread of the sensory response in layer 2/3 barrel cortex...