- Explorations in topology-delving underneath the surface of genetic interaction mapsMichal Breker
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel
Mol Biosyst 5:1473-81. 2009..In addition, we discuss potential applications for the study of evolution and disease mechanisms, and highlight the need for comprehensive integrative analysis to extract the wealth of information found in these maps...
- A novel single-cell screening platform reveals proteome plasticity during yeast stress responsesMichal Breker
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel
J Cell Biol 200:839-50. 2013..These include bet-hedging strategies, organelle rearrangement, and redistribution of protein localizations. All data are available for download through our online database, LOQATE (localization and quantitation atlas of yeast proteome)...
- Interactions of subunit CCT3 in the yeast chaperonin CCT/TRiC with Q/N-rich proteins revealed by high-throughput microscopy analysisMichal Nadler-Holly
Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100, Israel
Proc Natl Acad Sci U S A 109:18833-8. 2012..More generally, the strategy used in this work can be used to unravel the substrate specificities of other chaperone systems...