Affiliation: Weizmann Institute of Science
- Strategies to discover regulatory circuits of the mammalian immune systemIdo Amit
Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA
Nat Rev Immunol 11:873-80. 2011..Here, we review approaches for the reconstruction of signalling and transcriptional networks, with a focus on applications in the mammalian innate immune system...
- Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuliIrit Gat-Viks
Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Nat Biotechnol 31:342-9. 2013..Our approach charts an experimental and analytic path to decipher the mechanisms underlying genetic variation in circuits that control responses to stimuli...
- Semiconductor-based DNA sequencing of histone modification statesChristine S Cheng
Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA
Nat Commun 4:2672. 2013..We leverage this method for epigenetic profiling of tumour tissues. ..