Asaph Aharoni

Summary

Affiliation: Weizmann Institute of Science
Country: Israel

Publications

  1. pmc SHINE transcription factors act redundantly to pattern the archetypal surface of Arabidopsis flower organs
    Jian Xin Shi
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot, Israel
    PLoS Genet 7:e1001388. 2011
  2. pmc Fruit-surface flavonoid accumulation in tomato is controlled by a SlMYB12-regulated transcriptional network
    Avital Adato
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot, Israel
    PLoS Genet 5:e1000777. 2009
  3. doi request reprint Metabolic engineering of the plant primary-secondary metabolism interface
    Asaph Aharoni
    Department of Plant Sciences, The Weizmann Institute of Science, Rehovot 76100, Israel
    Curr Opin Biotechnol 22:239-44. 2011
  4. pmc Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species
    Asaph Aharoni
    Plant Research International, 6700 AA, Wageningen, The Netherlands
    Plant Cell 16:3110-31. 2004
  5. pmc The Arabidopsis DCR encoding a soluble BAHD acyltransferase is required for cutin polyester formation and seed hydration properties
    David Panikashvili
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel
    Plant Physiol 151:1773-89. 2009
  6. doi request reprint The tomato SlSHINE3 transcription factor regulates fruit cuticle formation and epidermal patterning
    Jian Xin Shi
    Department of Plant Sciences, Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel
    New Phytol 197:468-80. 2013
  7. pmc An orange ripening mutant links plastid NAD(P)H dehydrogenase complex activity to central and specialized metabolism during tomato fruit maturation
    Shai Nashilevitz
    Department of Plant Sciences, Weizman Institute of Science, Rehovot 76100, Israel
    Plant Cell 22:1977-97. 2010
  8. pmc Terpenoid metabolism in wild-type and transgenic Arabidopsis plants
    Asaph Aharoni
    Plant Research International, 6700 AA, Wageningen, The Netherlands
    Plant Cell 15:2866-84. 2003
  9. pmc GLYCOALKALOID METABOLISM1 is required for steroidal alkaloid glycosylation and prevention of phytotoxicity in tomato
    Maxim Itkin
    Department of Plant Sciences, Weizman Institute of Science, Rehovot, Israel
    Plant Cell 23:4507-25. 2011
  10. ncbi request reprint The Arabidopsis DSO/ABCG11 transporter affects cutin metabolism in reproductive organs and suberin in roots
    David Panikashvili
    Department of Plant Sciences, Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel
    Mol Plant 3:563-75. 2010

Collaborators

Detail Information

Publications49

  1. pmc SHINE transcription factors act redundantly to pattern the archetypal surface of Arabidopsis flower organs
    Jian Xin Shi
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot, Israel
    PLoS Genet 7:e1001388. 2011
    ..Furthermore, it will promote future investigation into the relation between the regulation of organ surface patterning and the broader control of flower development and biological functions...
  2. pmc Fruit-surface flavonoid accumulation in tomato is controlled by a SlMYB12-regulated transcriptional network
    Avital Adato
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot, Israel
    PLoS Genet 5:e1000777. 2009
    ..Hence, this work provides novel insight to the study of fleshy fruit cuticular structure and paves the way for the elucidation of the regulatory network that controls flavonoid accumulation in tomato fruit cuticle...
  3. doi request reprint Metabolic engineering of the plant primary-secondary metabolism interface
    Asaph Aharoni
    Department of Plant Sciences, The Weizmann Institute of Science, Rehovot 76100, Israel
    Curr Opin Biotechnol 22:239-44. 2011
    ....
  4. pmc Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species
    Asaph Aharoni
    Plant Research International, 6700 AA, Wageningen, The Netherlands
    Plant Cell 16:3110-31. 2004
    ..The findings shed light on the molecular evolutionary mechanisms resulting in different flavor profiles that are eventually selected for in domesticated species...
  5. pmc The Arabidopsis DCR encoding a soluble BAHD acyltransferase is required for cutin polyester formation and seed hydration properties
    David Panikashvili
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel
    Plant Physiol 151:1773-89. 2009
    ..Therefore, this study extends our knowledge regarding the functionality of the cuticular layer and the formation of its major constituent the polymer cutin...
  6. doi request reprint The tomato SlSHINE3 transcription factor regulates fruit cuticle formation and epidermal patterning
    Jian Xin Shi
    Department of Plant Sciences, Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel
    New Phytol 197:468-80. 2013
    ..This study provided insights into transcriptional mechanisms mediating fleshy fruit cuticle formation and highlighted the link between cutin metabolism and the process of fruit epidermal cell patterning...
  7. pmc An orange ripening mutant links plastid NAD(P)H dehydrogenase complex activity to central and specialized metabolism during tomato fruit maturation
    Shai Nashilevitz
    Department of Plant Sciences, Weizman Institute of Science, Rehovot 76100, Israel
    Plant Cell 22:1977-97. 2010
    ..This study therefore paves the way for further studies on the role of electron transport and redox reactions in the regulation of fruit ripening and its associated metabolism...
  8. pmc Terpenoid metabolism in wild-type and transgenic Arabidopsis plants
    Asaph Aharoni
    Plant Research International, 6700 AA, Wageningen, The Netherlands
    Plant Cell 15:2866-84. 2003
    ..This study further demonstrates the value of Arabidopsis for studies of the biosynthesis and ecological role of terpenoids and provides new insights into their metabolism in wild-type and transgenic plants...
  9. pmc GLYCOALKALOID METABOLISM1 is required for steroidal alkaloid glycosylation and prevention of phytotoxicity in tomato
    Maxim Itkin
    Department of Plant Sciences, Weizman Institute of Science, Rehovot, Israel
    Plant Cell 23:4507-25. 2011
    ..Together, these findings highlight the role of GAME1 in the glycosylation of SAs and in reducing the toxicity of SA metabolites to the plant cell...
  10. ncbi request reprint The Arabidopsis DSO/ABCG11 transporter affects cutin metabolism in reproductive organs and suberin in roots
    David Panikashvili
    Department of Plant Sciences, Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel
    Mol Plant 3:563-75. 2010
    ..Taken together, this study provides new insights into cutin and suberin metabolism and their role in reproductive organs and roots development...
  11. pmc The transcript and metabolite networks affected by the two clades of Arabidopsis glucosinolate biosynthesis regulators
    Sergey Malitsky
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel
    Plant Physiol 148:2021-49. 2008
    ....
  12. pmc The Arabidopsis DESPERADO/AtWBC11 transporter is required for cutin and wax secretion
    David Panikashvili
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel
    Plant Physiol 145:1345-60. 2007
    ..Thus, DSO is not only essential for developmental plasticity but also plays a vital role in stress responses...
  13. pmc The SHINE clade of AP2 domain transcription factors activates wax biosynthesis, alters cuticle properties, and confers drought tolerance when overexpressed in Arabidopsis
    Asaph Aharoni
    Plant Research International, 6700 AA, Wageningen, The Netherlands
    Plant Cell 16:2463-80. 2004
    ..We propose that these diverse functions are mediated by regulating metabolism of lipid and/or cell wall components...
  14. doi request reprint TOMATO AGAMOUS-LIKE 1 is a component of the fruit ripening regulatory network
    Maxim Itkin
    Department of Plant Sciences, Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel
    Plant J 60:1081-95. 2009
    ..The results add a new component to the current model of the regulatory network that controls fleshy fruit ripening and its association with the ethylene biosynthesis pathway...
  15. pmc Tomato fruits expressing a bacterial feedback-insensitive 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase of the shikimate pathway possess enhanced levels of multiple specialized metabolites and upgraded aroma
    Vered Tzin
    Department of Plant Sciences, Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel
    J Exp Bot 64:4441-52. 2013
    ....
  16. pmc Gene expression and metabolism in tomato fruit surface tissues
    Shira Mintz-Oron
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel
    Plant Physiol 147:823-51. 2008
    ..Peel-associated genes identified in our study, together with comparative analysis of genes enriched in surface tissues of various other plant species, establish a springboard for future investigations of plant surface biology...
  17. pmc Riboswitch-dependent gene regulation and its evolution in the plant kingdom
    Samuel Bocobza
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel
    Genes Dev 21:2874-9. 2007
    ..In an evolutionary perspective, a TPP riboswitch is also present in ancient plant taxa, suggesting that this mechanism is active since vascular plants emerged 400 million years ago...
  18. doi request reprint Expression of a bacterial feedback-insensitive 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase of the shikimate pathway in Arabidopsis elucidates potential metabolic bottlenecks between primary and secondary metabolism
    Vered Tzin
    Department of Plant Sciences, The Weizmann Institute of Science, Rehovot 76100, Israel
    New Phytol 194:430-9. 2012
    ..We propose that DAHPS is a key regulatory enzyme of the shikimate pathway. Moreover, our results shed light on additional potential metabolic bottlenecks bridging plant primary and secondary metabolism...
  19. pmc Orchestration of thiamin biosynthesis and central metabolism by combined action of the thiamin pyrophosphate riboswitch and the circadian clock in Arabidopsis
    Samuel E Bocobza
    Department of Plant Sciences, Weizman Institute of Science, 76100 Rehovot, Israel
    Plant Cell 25:288-307. 2013
    ....
  20. pmc Reconstruction of Arabidopsis metabolic network models accounting for subcellular compartmentalization and tissue-specificity
    Shira Mintz-Oron
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel
    Proc Natl Acad Sci U S A 109:339-44. 2012
    ..The reconstructed compartmentalized Arabidopsis tissue models are MIRIAM-compliant and are available upon request...
  21. doi request reprint Expression of a bacterial bi-functional chorismate mutase/prephenate dehydratase modulates primary and secondary metabolism associated with aromatic amino acids in Arabidopsis
    Vered Tzin
    Department of Plant Sciences, The Weizmann Institute of Science, Rehovot 76100, Israel
    Plant J 60:156-67. 2009
    ....
  22. pmc Improvement of water use efficiency in rice by expression of HARDY, an Arabidopsis drought and salt tolerance gene
    Aarati Karaba
    Plant Research International, Wageningen University and Research Centre, P O Box 16, 6700AA Wageningen, The Netherlands
    Proc Natl Acad Sci U S A 104:15270-5. 2007
    ..The results exemplify application of a gene identified from the model plant Arabidopsis for the improvement of water use efficiency coincident with drought resistance in the crop plant rice...
  23. ncbi request reprint Gene expression analysis of strawberry achene and receptacle maturation using DNA microarrays
    Asaph Aharoni
    Business Unit Cell Cybernetics, Plant Research International, PO Box 16, 6700 AA, Wageningen, The Netherlands
    J Exp Bot 53:2073-87. 2002
    ....
  24. pmc High-resolution metabolic mapping of cell types in plant roots
    Arieh Moussaieff
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel
    Proc Natl Acad Sci U S A 110:E1232-41. 2013
    ..The current study presents a work flow for metabolomics analyses of cell-type populations...
  25. pmc Functional characterization of enzymes forming volatile esters from strawberry and banana
    Jules Beekwilder
    Plant Research International, 6700 AA Wageningen, The Netherlands
    Plant Physiol 135:1865-78. 2004
    ..This confirmed that the availability of alcohol substrates is an important parameter to consider when engineering volatile ester formation in plants...
  26. doi request reprint The transcription factor SlSHINE3 modulates defense responses in tomato plants
    Kobi Buxdorf
    Department of Plant Pathology and Microbiology, The Robert H Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, P O Box 12, 76100, Rehovot, Israel
    Plant Mol Biol 84:37-47. 2014
    ..Cutin monomer content and composition differed between SlSHN3-OE, Slcyp86A69, Slshn3-RNAi and wild-type plants, and cutin monomer extracted from SlSHN3-OE plants altered the expression of pathogenesis-related genes in wild-type plants...
  27. doi request reprint Dual labeling of metabolites for metabolome analysis (DLEMMA): A new approach for the identification and relative quantification of metabolites by means of dual isotope labeling and liquid chromatography-mass spectrometry
    Liron Feldberg
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot, Israel
    Anal Chem 81:9257-66. 2009
    ..Hence, DLEMMA will complement and contribute to the advancement of metabolomics technologies and boost metabolic pathway discovery in diverse organisms...
  28. doi request reprint Non-targeted analysis of spatial metabolite composition in strawberry (Fragariaxananassa) flowers
    Kati Hanhineva
    Department of Plant Sciences, Weizmann Institute of Science, P O Box 26, Rehovot 76100, Israel
    Phytochemistry 69:2463-81. 2008
    ..These results allude to spatially-restricted production of secondary metabolite classes and specialized derivatives in flowers that take part in implementing the unique program of individual organs in the floral life cycle...
  29. doi request reprint The legwd mutant uncovers the role of starch phosphorylation in pollen development and germination in tomato
    Shai Nashilevitz
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot, Israel
    Plant J 57:1-13. 2009
    ..Overall, our results demonstrate the importance of starch phosphorylation and breakdown for pollen germination, and open up the prospect for analyzing the role of starch metabolism in leaves and fruits...
  30. pmc Novel insight into vascular, stress, and auxin-dependent and -independent gene expression programs in strawberry, a non-climacteric fruit
    Asaph Aharoni
    Business Unit Cell Cybernetics, Plant Research International, P O Box 16, 6700 AA, Wageningen, The Netherlands
    Plant Physiol 129:1019-31. 2002
    ..Novel auxin-dependent genes and processes were identified in addition to transcriptional programs acting independent of auxin mainly related to cell wall metabolism and stress response...
  31. pmc Mapping the diatom redox-sensitive proteome provides insight into response to nitrogen stress in the marine environment
    Shilo Rosenwasser
    Department of Plant Sciences and Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot 76100, Israel
    Proc Natl Acad Sci U S A 111:2740-5. 2014
    ..We propose that redox regulation of nitrogen metabolism allows rapid metabolic plasticity to ensure cellular homeostasis, and thus is essential for the ecological success of diatoms in the marine ecosystem. ..
  32. ncbi request reprint Volatile science? Metabolic engineering of terpenoids in plants
    Asaph Aharoni
    Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel
    Trends Plant Sci 10:594-602. 2005
    ..In addition to commercial applications, such transgenic plants should increase our understanding of the biological relevance of these volatile secondary metabolites...
  33. doi request reprint Switching the light on plant riboswitches
    Samuel E Bocobza
    Department of Plant Sciences, Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel
    Trends Plant Sci 13:526-33. 2008
    ..These discoveries not only trigger novel findings regarding RNA switches in plants, but also spur the exploitation of riboswitches for monitoring metabolite concentrations in planta...
  34. doi request reprint JA-Ile signalling in Solanum nigrum is not required for defence responses in nature
    Arjen VanDoorn
    Department of Molecular Ecology, Max Planck Institute for Chemical Ecology, D 07745 Jena, Germany
    Plant Cell Environ 34:2159-71. 2011
    ..Together, these results reveal that SnJAR4 does not play a direct role in herbivore defence, but suggests that SnJAR4 is involved in responses other than those to herbivory...
  35. pmc Reverse genetics of floral scent: application of tobacco rattle virus-based gene silencing in Petunia
    Ben Spitzer
    Robert H Smith Institute of Plant Sciences and Genetics in Agriculture, Hebrew University of Jerusalem, Rehovot 76100, Israel
    Plant Physiol 145:1241-50. 2007
    ....
  36. doi request reprint Arabidopsis thaliana plants with different levels of aliphatic- and indolyl-glucosinolates affect host selection and performance of Bemisia tabaci
    Oshry Markovich
    Department of Entomology, Faculty of Agriculture, The Hebrew University of Jerusalem, Rehovot, 76100, Israel
    J Chem Ecol 39:1361-72. 2013
    ..Overall, our findings are consistent with the view that both performance and selectivity of B. tabaci decrease in heterogeneous habitats that contain plants with closely-related chemical signatures...
  37. ncbi request reprint The Arabidopsis ABCG13 transporter is required for flower cuticle secretion and patterning of the petal epidermis
    David Panikashvili
    Department of Plant Sciences, Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel Institute of Cellular and Molecular Botany IZMB, Department of Ecophysiology, University of Bonn, Kirschallee 1, D 53115 Bonn, Germany
    New Phytol 190:113-24. 2011
    ....
  38. doi request reprint The challenges of cellular compartmentalization in plant metabolic engineering
    Uwe Heinig
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot 76100, Israel
    Curr Opin Biotechnol 24:239-46. 2013
    ..The availability of compartmentalized metabolic network models for plants in the near future will greatly advance the integration of localization constraints in metabolic engineering experiments and aid in predicting their outcomes...
  39. pmc Overexpression of AtSHN1/WIN1 provokes unique defense responses
    Dikla Sela
    Department of Plant Pathology and Microbiology, The Robert H Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel
    PLoS ONE 8:e70146. 2013
    ....
  40. ncbi request reprint Nontargeted metabolome analysis by use of Fourier Transform Ion Cyclotron Mass Spectrometry
    Asaph Aharoni
    Business Unit Cell Cybernetics, Plant Research International, Wageningen, The Netherlands
    OMICS 6:217-34. 2002
    ....
  41. doi request reprint UPLC-MS-based metabolite analysis in tomato
    Ilana Rogachev
    Department of Plant Sciences, The Weizmann Institute of Science, Rehovot, Israel
    Methods Mol Biol 860:129-44. 2012
    ..When coupled to a TOF mass spectrometer with high resolution and mass accuracy, good dynamic range, and a fast spectral acquisition capacity, this system is most suitable for the extensive profiling of hundreds of plant metabolites...
  42. doi request reprint Evaluation of peak picking quality in LC-MS metabolomics data
    Leonid Brodsky
    Department of Plant Sciences, Weizmann Institute of Science, P O Box 26, Rehovot 76100, Israel
    Anal Chem 82:9177-87. 2010
    ..We expect this method to aid in the accurate analysis of metabolomics data and in the development of new peak-picking/alignment procedures...
  43. doi request reprint Genetic control over silica deposition in wheat awns
    Zvi Peleg
    The Robert H Smith Institute of Plant Sciences and Genetics in Agriculture, The Hebrew University of Jerusalem, Rehovot 76100, Israel
    Physiol Plant 140:10-20. 2010
    ..7-6.3, three of which overlapped genomic regions that contribute to high grain protein. Localization of silica in the awns and identification of QTLs help illuminate mechanisms associated with silica metabolism in wheat...
  44. ncbi request reprint Analysis of steroidal alkaloids and saponins in Solanaceae plant extracts using UPLC-qTOF mass spectrometry
    Uwe Heinig
    Department of Plant Sciences, Weizmann Institute of Science, 243 Hertzl Street, Rehovot, 76100, Israel
    Methods Mol Biol 1153:171-85. 2014
    ..The described methodology allows profiling and putative identification of multiple steroidal glycoside compounds from the assortment of Solanaceae species producing these molecules. ..
  45. ncbi request reprint DNA microarrays for functional plant genomics
    Asaph Aharoni
    Business Unit Cell Cybernetics, Plant Research International, Wageningen, The Netherlands
    Plant Mol Biol 48:99-118. 2002
    ....
  46. pmc Network-based prediction of metabolic enzymes' subcellular localization
    Shira Mintz-Oron
    Department of Plant Sciences, Weizmann Institute of Science, Rehovot, Israel
    Bioinformatics 25:i247-52. 2009
    ..However, as high-throughput PPI data depend on costly high-throughput experiments and are currently available for only a few organisms, the scope of such methods is yet limited...
  47. ncbi request reprint Genetic engineering of terpenoid metabolism attracts bodyguards to Arabidopsis
    Iris F Kappers
    Laboratory of Entomology, Wageningen University, Post Office Box 8031, 6700 EH Wageningen, Netherlands
    Science 309:2070-2. 2005
    ..These altered plants attracted carnivorous predatory mites (Phytoseiulus persimilis) that aid the plants' defense mechanisms...
  48. pmc Cinnamate metabolism in ripening fruit. Characterization of a UDP-glucose:cinnamate glucosyltransferase from strawberry
    Stefan Lunkenbein
    Biomolecular Food Technology, Technical University Munich, Freising, Germany
    Plant Physiol 140:1047-58. 2006
    ....
  49. pmc Redirection of flavonoid biosynthesis through the down-regulation of an anthocyanidin glucosyltransferase in ripening strawberry fruit
    Markus Griesser
    Biomolecular Food Technology, Technical University Munich, 85354 Freising, Germany
    Plant Physiol 146:1528-39. 2008
    ..These results demonstrate a method to redirect the anthocyanin biosynthesis into flavan-3-ol production to increase the levels of bioactive natural products or modify pigments in plant tissues...