Sami Viskin

..Data on the incidence and significance of catheter-induced trauma to fast and slow pathways are scarce...

..This study was undertaken to determine whether the short-lived sinus tachycardia that occurs during standing will expose changes in the QT interval that are of diagnostic value...

..The purpose of this study was to determine if patients with idiopathic ventricular fibrillation (VF) have shorter QT intervals than comparable healthy controls...

..It is important to define the percentage of physicians capable of distinguishing QT intervals that are long from those that are normal because LQTS can be lethal when left untreated...

..The unusual aspect of their RVOT-extrasystoles was their coupling interval, which appears to be intermediate between the ultra-short coupling interval of idiopathic VF and the long coupling interval seen in the truly benign RVOT-VT...

..However, data supporting this dogma originate from patients without previously documented ventricular tachyarrhythmias. We examined the significance of ventricular flutter in patients with and without spontaneous ventricular arrhythmias...

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..In addition, we reviewed the published reviews and the Internet sites dealing with drug-induced arrhythmias. All the original articles quoted in these reviews and Web sites were examined critically...

..The purpose of this study was to define the electrocardiographic (ECG) predictors of torsade de pointes (TdP) during acquired bradyarrhythmias...

..We now validate our original observations in a cohort twice as large. We also describe that this abnormal QT-interval response persists as the heart rate acceleration returns to baseline...

..The purpose of this study was to determine whether J-point elevation is a marker of arrhythmic risk...

..The predictive value of electrophysiologic studies depends on the aggressiveness of the programmed ventricular stimulation protocol...

..However, although beta-blockers prevent exercise-induced ventricular tachycardia (VT), most patients continue to have ventricular ectopy during exercise, and some studies report high mortality rates despite beta-blockade...

..Radiofrequency ablation has been suggested as first-line therapy in the management of accessory pathways. There are limited data on the results of ablation over years of experience...

..The purpose of this study was to determine if pre-participation screening of athletes with a strategy including resting and exercise electrocardiography (ECG) reduces their risk for sudden death...

..Quinidine depresses I(to) current, which may play an important role in the arrhythmogenesis of this disease...

..This study sought to estimate the costs of a national electrocardiographic (ECG) screening of athletes in the United States and the number of lives that would be saved by that program...

..We therefore speculated that the combination of "J waves with horizontal ST segment" would correlate with a history of idiopathic ventricular fibrillation (VF) better than the mere presence of J waves...

..CONCLUSIONS: Atrioventricular block is commonly "related to drugs" but is rarely "caused by drugs."..

..Our study suggests that almost all patients with torsade de pointes secondary to noncardiac drugs have risk factors that can be easily identified from the medical history before the initiation of therapy with the culprit drug...

..Despite long-lasting catheter trauma to the RAFP, mapping of the tricuspid annulus showed persistent recording of an AP potential that enabled us to continue the procedure and successfully abolish the AP...

..Although we performed RFA of the slow pathway in patients with inducible AVNRT and no prior tachycardia documentation, the question whether this is mandatory remains unsettled...

..However, there are no data on the long-term reproducibility of this EP efficacy...

..The use of a "two-catheter approach" (one diagnostic and one ablation) was as effective and safe as a multi-catheter approach...

..Head-up tilt-table (HUT) testing is an easy way to achieve brisk sympathetic stimulation. Yet, little is known about the response of the QT interval to HUT...

..Although RF ablation of atrial flutter is the most frequently performed ablation procedure, data on the incidence and significance of an AV block occurring during the procedure are scarce...

..A sensible approach for the asymptomatic patient with J waves is proposed...

..7 beats per minute (P< 0.001). These results were achieved within the first 37 +/- 11 minutes. CONCLUSIONS: Intravenous chlorpromazine is safe and effective when used as emergency treatment for uncontrolled symptomatic hypertension...

..A single radiofrequency pulse delivered at this site resulted in definite cure of the arrhythmia...

..Less is known about the site of onset of this arrhythmia. This study was conducted to determine if arrhythmias in the long QT syndrome (LQTS) have a predominant site of origin...

..We sought to take advantage of ivabradine's ability to decrease the maximal obtainable sinus rate in order to prevent inappropriate shocks due to sinus tachycardia in patients with an implanted cardioverter defibrillator (ICD)...

..IS showed lymphocytosis, a high CD4 or CD8 count, eosinophilia and amiodarone in 3 of 4 patients. IS may be a useful tool for assessing amiodarone toxicity in patients with ischemic heart diseases and concomitant pulmonary side effects...

..CONCLUSION: The long-term prognosis of patients with inducible VFL is similar to that of patients with inducible SMVT, even when VFL is induced with a relatively aggressive protocol...

..No predictors could be found for high and low risk for unstable arrhythmias. These findings support ICD treatment for stable VT survivors...

..Ventricular tachycardia (VT) and ventricular fibrillation (VF) complicating Brugada syndrome, a genetic disorder linked to SCN5A mutations, and VF complicating acute myocardial infarction (AMI) both have been linked to phase 2 reentry...

..These preliminary studies provide support for the hypothesis that there is a genetic predisposition to the type and severity of arrhythmias that develop during and after an AMI, and that additional studies are warranted...