Eviatar Nevo

Summary

Affiliation: University of Haifa
Country: Israel

Publications

  1. pmc Adaptive response to DNA-damaging agents in natural Saccharomyces cerevisiae populations from "Evolution Canyon", Mt. Carmel, Israel
    Gabriel A Lidzbarsky
    Institute of Evolution, Department of Evolutionary and Environmental Biology, Faculty of Science and Science Education, University of Haifa, Haifa, Israel
    PLoS ONE 4:e5914. 2009
  2. pmc Can chimpanzee biology highlight human origin and evolution?
    Itai Roffman
    International Graduate Center of Evolution, Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel
    Rambam Maimonides Med J 1:e0009. 2010
  3. pmc SNP-revealed genetic diversity in wild emmer wheat correlates with ecological factors
    Jing Ren
    Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Chinese Academy of Sciences, Wuhan, Hubei 430074, China
    BMC Evol Biol 13:169. 2013
  4. pmc Population-genetic analysis of HvABCG31 promoter sequence in wild barley (Hordeum vulgare ssp. spontaneum)
    Xiaoying Ma
    Extreme Stress Resistance and Biotechnology Laboratory, Cold and Arid Regions Environmental and Engineering Institute, Chinese Academy of Sciences, Lanzhou 730000, China
    BMC Evol Biol 12:188. 2012
  5. doi request reprint Stress, adaptation, and speciation in the evolution of the blind mole rat, Spalax, in Israel
    Eviatar Nevo
    Institute of Evolution, University of Haifa, Mt Carmel, Haifa 31905, Israel
    Mol Phylogenet Evol 66:515-25. 2013
  6. pmc Evolution of wild cereals during 28 years of global warming in Israel
    Eviatar Nevo
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 109:3412-5. 2012
  7. pmc "Evolution Canyon," a potential microscale monitor of global warming across life
    Eviatar Nevo
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 109:2960-5. 2012
  8. pmc Genomic, RNA, and ecological divergences of the Revolver transposon-like multi-gene family in Triticeae
    Motonori Tomita
    Molecular Genetics Laboratory, Faculty of Agriculture, Tottori University, Tottori 680 8553, Japan
    BMC Evol Biol 11:269. 2011
  9. pmc Molecular evolution of dimeric alpha-amylase inhibitor genes in wild emmer wheat and its ecological association
    Ji Rui Wang
    Triticeae Research Institute, Sichuan Agricultural University, Yaan, Sichuan 625014, China
    BMC Evol Biol 8:91. 2008
  10. pmc The impact of single nucleotide polymorphism in monomeric alpha-amylase inhibitor genes from wild emmer wheat, primarily from Israel and Golan
    Ji Rui Wang
    Triticeae Research Institute, Sichuan Agricultural University, Yaan, China
    BMC Evol Biol 10:170. 2010

Detail Information

Publications150 found, 100 shown here

  1. pmc Adaptive response to DNA-damaging agents in natural Saccharomyces cerevisiae populations from "Evolution Canyon", Mt. Carmel, Israel
    Gabriel A Lidzbarsky
    Institute of Evolution, Department of Evolutionary and Environmental Biology, Faculty of Science and Science Education, University of Haifa, Haifa, Israel
    PLoS ONE 4:e5914. 2009
    ..Here we studied the phenotypic response of the S. cerevisiae strains to UVA and UVC radiations and to methyl methanesulfonate (MMS) in order to evaluate the interslope effect on the strains' ability to withstand DNA-damaging agents...
  2. pmc Can chimpanzee biology highlight human origin and evolution?
    Itai Roffman
    International Graduate Center of Evolution, Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel
    Rambam Maimonides Med J 1:e0009. 2010
    ..Unfolding bonobo and chimpanzee biology highlights our common genetic and cultural evolutionary origins. ..
  3. pmc SNP-revealed genetic diversity in wild emmer wheat correlates with ecological factors
    Jing Ren
    Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Chinese Academy of Sciences, Wuhan, Hubei 430074, China
    BMC Evol Biol 13:169. 2013
    ..However, few studies have been performed on the genetic structure and population divergence in wild emmer wheat using a large number of EST-related single nucleotide polymorphism (SNP) markers...
  4. pmc Population-genetic analysis of HvABCG31 promoter sequence in wild barley (Hordeum vulgare ssp. spontaneum)
    Xiaoying Ma
    Extreme Stress Resistance and Biotechnology Laboratory, Cold and Arid Regions Environmental and Engineering Institute, Chinese Academy of Sciences, Lanzhou 730000, China
    BMC Evol Biol 12:188. 2012
    ..The sites included three mesic and two xeric habitats, and differed in annual rainfall, soil type, and soil water capacity...
  5. doi request reprint Stress, adaptation, and speciation in the evolution of the blind mole rat, Spalax, in Israel
    Eviatar Nevo
    Institute of Evolution, University of Haifa, Mt Carmel, Haifa 31905, Israel
    Mol Phylogenet Evol 66:515-25. 2013
    ..It involves multiple adaptive complexes to life underground and is an evolutionary model to a few hundred underground mammals. It involves great promise in the future for medicine, space flight, and deep-sea diving...
  6. pmc Evolution of wild cereals during 28 years of global warming in Israel
    Eviatar Nevo
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 109:3412-5. 2012
    ..The revealed evolutionary changes imply unrealized risks present in genetic resources for crop improvement and human food production...
  7. pmc "Evolution Canyon," a potential microscale monitor of global warming across life
    Eviatar Nevo
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 109:2960-5. 2012
    ..The EC microclimatic model is optimal to track global warming at a microscale across life from viruses and bacteria to mammals in Israel, and in additional ECs across the planet...
  8. pmc Genomic, RNA, and ecological divergences of the Revolver transposon-like multi-gene family in Triticeae
    Motonori Tomita
    Molecular Genetics Laboratory, Faculty of Agriculture, Tottori University, Tottori 680 8553, Japan
    BMC Evol Biol 11:269. 2011
    ..A putative TATA box is located at base 221, with a cap site at base 261 and a possible polyadenylation signal AATAAA at base 2918. Revolver shows considerable quantitative variation in wheat and its relatives...
  9. pmc Molecular evolution of dimeric alpha-amylase inhibitor genes in wild emmer wheat and its ecological association
    Ji Rui Wang
    Triticeae Research Institute, Sichuan Agricultural University, Yaan, Sichuan 625014, China
    BMC Evol Biol 8:91. 2008
    ..Another objective of this study was to find out whether there were any correlations between SNPs in functional protein-coding genes and the environment...
  10. pmc The impact of single nucleotide polymorphism in monomeric alpha-amylase inhibitor genes from wild emmer wheat, primarily from Israel and Golan
    Ji Rui Wang
    Triticeae Research Institute, Sichuan Agricultural University, Yaan, China
    BMC Evol Biol 10:170. 2010
    ....
  11. ncbi request reprint Ernst Mayr (1904-2005): evolutionary leader, protagonist, and visionary
    Eviatar Nevo
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel
    Theor Popul Biol 70:105-10. 2006
  12. pmc Evolution under environmental stress at macro- and microscales
    Eviatar Nevo
    Institute of Evolution, University of Haifa, Haifa, Israel
    Genome Biol Evol 3:1039-52. 2011
    ....
  13. pmc Evolution of genome-phenome diversity under environmental stress
    E Nevo
    Institute of Evolution, University of Haifa, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 98:6233-40. 2001
    ....
  14. ncbi request reprint Extraordinary multilocus genetic organization in mole crickets, Gryllotalpidae
    E Nevo
    Institute of Evolution, University of Haifa, Israel
    Evolution 54:586-605. 2000
    ..Simulations based on this model showed that a combination of these three mechanisms may produce the observed distribution of alleles, via selection on a few loci, to affect the entire genome organization...
  15. ncbi request reprint Molecular evolution of cytochrome b of subterranean mole rats, Spalax ehrenbergi superspecies, in Israel
    E Nevo
    Institute of Evolution, University of Haifa, Haifa 31905, Israel
    J Mol Evol 49:215-26. 1999
    ..Thus, the molecular evolution of mitochondrial cytochrome b in S. ehrenbergi is explicable by opposite selective stresses across the range of S. ehrenbergi in Israel, associated with the ecological adaptive radiation of the complex...
  16. doi request reprint Drought and salt tolerances in wild relatives for wheat and barley improvement
    Eviatar Nevo
    Institute of Evolution and the International Graduate Center of Evolution, University of Haifa, Israel
    Plant Cell Environ 33:670-85. 2010
    ..Wild genetic resistances to drought and salinity will be shifted in the future from field experiments to the farmer...
  17. pmc A MAPK gene from Dead Sea fungus confers stress tolerance to lithium salt and freezing-thawing: Prospects for saline agriculture
    Yan Jin
    Institute of Evolution, University of Haifa, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 102:18992-7. 2005
    ..The Dead Sea is potentially an excellent model for studies of evolution under extreme environments and is an important gene pool for future agricultural genetic engineering prospects...
  18. doi request reprint Multilevel regulation and signalling processes associated with adaptation to terminal drought in wild emmer wheat
    Tamar Krugman
    Department of Evolutionary and Environmental Biology, Institute of Evolution, Faculty of Natural Sciences, University of Haifa, Mt Carmel, Haifa, 31905, Israel
    Funct Integr Genomics 10:167-86. 2010
    ..These results demonstrate the potential of wild emmer wheat as a source for candidate genes for improving drought resistance...
  19. pmc Evolution of genomic diversity and sex at extreme environments: fungal life under hypersaline Dead Sea stress
    Tamar Kis-Papo
    Institute of Evolution, University of Haifa, Mt Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 100:14970-5. 2003
    ..Future large-scale verification in micromycetes will define further the trajectories of diversity and sex in the rise and fall pattern...
  20. ncbi request reprint Identification of a novel gene (Hsdr4) involved in water-stress tolerance in wild barley
    Tatiana Suprunova
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Plant Mol Biol 64:17-34. 2007
    ..Furthermore, the Hsdr4 gene was mapped using wild barley mapping population to the long arm of chromosome 3H between markers EBmac541 and EBmag705, within a region that previously was shown to affect osmotic adaptation in barley...
  21. pmc Sympatric incipient speciation of spiny mice Acomys at "Evolution Canyon," Israel
    Yarin Hadid
    Institute of Evolution and Department of Evolutionary and Environmental Biology, University of Haifa, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 111:1043-8. 2014
    ..We conclude that Acomys at the EC is ecologically and genetically adaptively, incipiently, sympatrically speciating on the ES owing to adaptive microclimatic natural selection. ..
  22. ncbi request reprint Evidence for multiple lateral transfers of the circadian clock cluster in filamentous heterocystic cyanobacteria Nostocaceae
    Volodymyr Dvornyk
    Institute of Evolution, University of Haifa, Mount Carmel, 31905 Haifa, Israel
    J Mol Evol 58:341-7. 2004
    ..The data obtained suggest that lateral transfers of the circadian clock cluster in filamentous cyanobacteria have been common and might have adaptive significance...
  23. ncbi request reprint En/Spm-like transposons in Poaceae species: transposase sequence variability and chromosomal distribution
    Ahu Altinkut
    Institute of Evolution, University of Haifa, Mt Carmel, Haifa, Israel
    Cell Mol Biol Lett 11:214-30. 2006
    ..The sequence data from this article was deposited in the EMBL/GenBank Data Libraries under the accession nos. AY707995-AY707996-AY707997-AY707998-AY707999-AY708000-AY708001-AY708002-AY708003-AY708004-AY708005-AY708005-AY265312...
  24. ncbi request reprint DNA repair efficiency and thermotolerance in Drosophila melanogaster from "Evolution Canyon"
    Achsa Lupu
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Mutagenesis 19:383-90. 2004
    ..The results suggest the existence of a relationship between DNA repair efficiency and thermotolerance, with thermotolerant lines tending to repair DNA more efficiently than thermosensitive ones...
  25. pmc Adaptation of pelage color and pigment variations in israeli subterranean blind mole rats, Spalax ehrenbergi
    Natarajan Singaravelan
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel
    PLoS ONE 8:e69346. 2013
    ..e., the causal chain) synergize to configure it. This study investigates the causal chain of dorsal coloration in Israeli subterranean blind mole rats, Spalax ehrenbergi...
  26. ncbi request reprint p53--a key player in tumoral and evolutionary adaptation: a lesson from the Israeli blind subterranean mole rat
    Aaron Avivi
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel
    Cell Cycle 4:368-72. 2005
    ....
  27. doi request reprint Alteration in expression of hormone-related genes in wild emmer wheat roots associated with drought adaptation mechanisms
    Tamar Krugman
    Department of Evolutionary and Environmental Biology, Institute of Evolution, Faculty of Natural Sciences, University of Haifa, Mt Carmel, Haifa, Israel
    Funct Integr Genomics 11:565-83. 2011
    ....
  28. doi request reprint Ecological genomics of natural plant populations: the Israeli perspective
    Eviatar Nevo
    Institute of Evolution and the International Graduate Center of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Methods Mol Biol 513:321-44. 2009
    ..Future studies should focus on the interplay between structural and functional genome organization focusing on gene regulation...
  29. pmc Domestication quantitative trait loci in Triticum dicoccoides, the progenitor of wheat
    Junhua Peng
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 100:2489-94. 2003
    ..The A genome of wheat may have played a more important role than the B genome during domestication evolution. The cryptic beneficial alleles at specific QTLs derived from T. dicoccoides may contribute to wheat and cereal improvement...
  30. ncbi request reprint Erythropoietin receptor spliced forms differentially expressed in blind subterranean mole rats
    Imad Shams
    Laboratory of Animal Molecular Evolution, Institute of Evolution, University of Haifa, Mt Carmel, Haifa, Israel
    FASEB J 19:1749-51. 2005
    ..Severe hypoxia induces a significant increase in adult Rattus EpoR. Our data provide further insight into the adaptive mechanisms of Spalax to the extreme conditions of hypoxia in its subterranean environment...
  31. pmc Mammalian microevolution in action: adaptive edaphic genomic divergence in blind subterranean mole-rats
    Andrei Polyakov
    Institute of Evolution, University of Haifa, Haifa 31905, Israel
    Proc Biol Sci 271:S156-9. 2004
    ..Natural selection is the only evolutionary adaptive force that can cause genetic divergence across the genome matching the sharp microscale ecological contrast...
  32. pmc A binary search approach to whole-genome data analysis
    Leonid Brodsky
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 107:16893-8. 2010
    ..The algorithm generates an accurate whole-genome landscape that could be used for cross-comparison of signals across the same genome in evolutionary and general genomic studies...
  33. pmc Adaptive evolution of heparanase in hypoxia-tolerant Spalax: gene cloning and identification of a unique splice variant
    Nicola J Nasser
    Institute of Evolution, International Graduate Center of Evolution, University of Haifa, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 102:15161-6. 2005
    ....
  34. ncbi request reprint Ac-like transposons in populations of wild diploid Triticeae species: comparative analysis of chromosomal distribution
    Ahu Altinkut
    Institute of Evolution, University of Haifa, Mt Carmel, Haifa, 31905, Israel
    Chromosome Res 14:307-17. 2006
    ....
  35. ncbi request reprint Ecological-genetic feedback in DNA repair in wild barley, Hordeum spontaneum
    Achsa Lupu
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa, 31905, Israel
    Genetica 127:121-32. 2006
    ..Such a dependence of DNA integrity on environment and genotype may serve an important factor for maintaining relatively high level of mutability without increasing the genetic load...
  36. ncbi request reprint The Shaggy Inc Cap medicinal mushroom, Coprinus comatus (O.F.Mull.: Fr.) Pers. (Agaricomycetideae) substances interfere with H2O2 induction of the NF-kappaB pathway through inhibition of Ikappaalpha phosphorylation in MCF7 breast cancer cells
    Mikheil D Asatiani
    Department of Evolutionary and Environmental Biology, Faculty of Natural Sciences and Institute of Evolution, University of Haifa, Mt Carmel, Haifa, Israel
    Int J Med Mushrooms 13:19-25. 2011
    ..These results suggest that C. comatus contains potent compounds capable of inhibiting NF-kappaB function and also possibly acts as an antitumor agent...
  37. doi request reprint Ancient diversity of splicing motifs and protein surfaces in the wild emmer wheat (Triticum dicoccoides) LR10 coiled coil (CC) and leucine-rich repeat (LRR) domains
    Hanan Sela
    Department of Evolutionary and Environmental Biology, Institute of Evolution, University of Haifa, Mt Carmel, Haifa 31905, Israel
    Mol Plant Pathol 13:276-87. 2012
    ..The two haplotypes are proposed to be ancient and maintained by balancing selection...
  38. pmc Adaptive melanin response of the soil fungus Aspergillus niger to UV radiation stress at "Evolution Canyon", Mount Carmel, Israel
    Natarajan Singaravelan
    Institute of Evolution, University of Haifa, Mount Carmel, Israel
    PLoS ONE 3:e2993. 2008
    ..We test the working hypothesis that the AS strains exhibit higher melanin content than strains from the ES resulting in higher UV resistance...
  39. ncbi request reprint Circadian genes in a blind subterranean mammal III: molecular cloning and circadian regulation of cryptochrome genes in the blind subterranean mole rat, Spalax ehrenbergi superspecies
    Aaron Avivi
    Laboratory of Animal Molecular Evolution, Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    J Biol Rhythms 19:22-34. 2004
    ..Once again, the results indicate that the uniquely hypertrophied harderian gland of Spalax plays a key role in its circadian system...
  40. ncbi request reprint Differential expression profiling of the blind subterranean mole rat Spalax ehrenbergi superspecies: bioprospecting for hypoxia tolerance
    Aaron Avivi
    Institute of Evolution, University of Haifa, Haifa, Israel
    Physiol Genomics 27:54-64. 2006
    ..ehrenbergi superspecies are variably adapted to fluctuating oxygen tension. Differences may involve specific metabolic pathways and functional adaptations at the structural and molecular levels...
  41. ncbi request reprint Large-scale genome clustering across life based on a linguistic approach
    Valery Kirzhner
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Biosystems 81:208-22. 2005
    ..We believe that our approach provides a new and wider (compared to traditional methods) perspective of extracting genomic information of high evolutionary relevance...
  42. ncbi request reprint Marasmius oreades substances block NF-kappaB activity through interference with IKK activation pathway
    Roumyana D Petrova
    International Center for Cryptogamic Plants and Fungi, Institute of Evolution, University of Haifa, Mt Carmel, Haifa 31905, Israel
    Mol Biol Rep 36:737-44. 2009
    ..oreades as a natural source of low-molecular-weight bioactive substances able to affect the process of tumorogenesis through the direct blockage of NF-kappaB activation at the IKK level...
  43. pmc Spiny mice modulate eumelanin to pheomelanin ratio to achieve cryptic coloration in "evolution canyon," Israel
    Natarajan Singaravelan
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel
    PLoS ONE 5:e8708. 2010
    ..Here, we examine how hair melanin content of spiny mice living in the opposing slopes of EC evolves toward blending with their respective background habitat...
  44. pmc Drosophila flies in "Evolution Canyon" as a model for incipient sympatric speciation
    Abraham Korol
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 103:18184-9. 2006
    ..We suggest that Drosophila populations at EC represent a rare example, demonstrating how selection overrides migration, and propose an ad hoc ecological model of incipient sympatric divergence...
  45. ncbi request reprint Allelic diversity associated with aridity gradient in wild emmer wheat populations
    Zvi Peleg
    The Institute of Evolution, University of Haifa, Mt Carmel, Haifa 31905, Israel
    Plant Cell Environ 31:39-49. 2008
    ....
  46. ncbi request reprint Differential expression of small heat shock protein genes Hsp23 and Hsp40, and heat shock gene Hsr-omega in fruit flies (Drosophila melanogaster) along a microclimatic gradient
    Julie Carmel
    Institute of Evolution, Department of Evolutionary and Environmental Biology, Faculty of Science and Science Education, University of Haifa, Mount Carmel, Haifa, Israel
    J Hered 102:593-603. 2011
    ..74; P < 0.001, based on the Spearman rank correlation test) and induced thermotolerance (R = 0.78; P < 0.0001), implying a significant contribution of Hsp40 gene in thermoadaptation...
  47. pmc Possible incipient sympatric ecological speciation in blind mole rats (Spalax)
    Yarin Hadid
    Institute of Evolution, University of Haifa, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 110:2587-92. 2013
    ..Sympatric ecological speciation may be more prevalent in nature because of abundant and sharply abutting divergent ecologies...
  48. pmc Growth and asymmetry of soil microfungal colonies from "Evolution Canyon," Lower Nahal Oren, Mount Carmel, Israel
    Shmuel Raz
    Department of Evolutionary and Environmental Biology, Institute of Evolution, University of Haifa, Haifa, Israel
    PLoS ONE 7:e34689. 2012
    ..These individual, signed asymmetries are symmetrically distributed around a mean of zero. Fluctuating asymmetry, however, has rarely been studied in microorganisms, and never in fungi...
  49. pmc Origin and evolution of circadian clock genes in prokaryotes
    Volodymyr Dvornyk
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 100:2495-500. 2003
    ....
  50. ncbi request reprint Ontogenetic expression of erythropoietin and hypoxia-inducible factor-1 alpha genes in subterranean blind mole rats
    Imad Shams
    Laboratory of Animal Molecular Evolution, Institute of Evolution, University of Haifa, Mt Carmel, Haifa, Israel
    FASEB J 19:307-9. 2005
    ..Spalax expresses remarkably higher levels of HIF-1alpha mRNA than Rattus at all developmental stages studied, which peaked in neonates, as an adaptation against hypoxia...
  51. pmc Adaptation and incipient sympatric speciation of Bacillus simplex under microclimatic contrast at "Evolution Canyons" I and II, Israel
    Johannes Sikorski
    Institute of Evolution, International Graduate Center of Evolution, University of Haifa, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 102:15924-9. 2005
    ..We conclude that, despite different biology, prokaryotes, like sexually reproducing eukaryotes, may consist of true species and parallel ecological speciation in eukaryotes...
  52. doi request reprint Rapid linkage disequilibrium decay in the Lr10 gene in wild emmer wheat (Triticum dicoccoides) populations
    Hanan Sela
    Department of Evolutionary and Environmental Biology, Institute of Evolution, Faculty of Natural Sciences, University of Haifa, Mt Carmel, Haifa, 31905, Israel
    Theor Appl Genet 122:175-87. 2011
    ..Lr10 is a leaf rust resistance gene encoding three domains: a coiled-coil, nucleotide-binding site, and leucine-rich repeat (CC-NBS-LRR)...
  53. pmc Long-term microclimatic stress causes rapid adaptive radiation of kaiABC clock gene family in a cyanobacterium, Nostoc linckia, from "Evolution Canyons" I and II, Israel
    Volodymyr Dvornyk
    Institute of Evolution, University of Haifa, Mount Carmel, 31905 Haifa, Israel
    Proc Natl Acad Sci U S A 99:2082-7. 2002
    ..The observed patterns of within- and between-subfamily polymorphisms indicate that positive diversifying, balancing, and purifying selections are the principal driving forces of the kai gene family's evolution...
  54. pmc Genome differentiation of Drosophila melanogaster from a microclimate contrast in Evolution Canyon, Israel
    Sariel Hübner
    Institute of Evolution, Haifa University, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 110:21059-64. 2013
    ..Positive correlation between local recombination rate and the level of nucleotide polymorphism was also found. ..
  55. doi request reprint Antidiabetic attributes of desert and steppic plants: a review
    Eli Harlev
    Institute of Evolution and International Graduate Center of Evolution, University of Haifa, Mount Carmel, Haifa, Israel
    Planta Med 79:425-36. 2013
    ..The review concludes in summarizing the work done on the subject and also in pointing to the yet existing gaps in diabetes research of desert and steppic plants, and suggests directions for future exploration...
  56. pmc Evolution and genetic population structure of prickly lettuce (Lactuca serriola) and its RGC2 resistance gene cluster
    Hanhui Kuang
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Genetics 178:1547-58. 2008
    ..We hypothesize that the high genomewide diversity and diversity of the RGC2 cluster in eastern Turkish and Armenian populations resulted from high abiotic and biotic stresses in the regions of origin of L. serriola...
  57. ncbi request reprint A large-scale comparison of genomic sequences: one promising approach
    Valery Kirzhner
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Acta Biotheor 51:73-89. 2003
    ..High flexibility characterizes this approach due to imperfect matching and as a result sets of relatively long words can be considered. The proposed approach may have various applications in intra- and intergenomic sequence comparisons...
  58. doi request reprint Pathogen race determines the type of resistance response in the stripe rust-Triticum dicoccoides pathosystem
    Jianping Cheng
    Department of Evolutionary and Environmental Biology, Institute of Evolution, Faculty of Science and Science Education, University of Haifa, Mt Carmel, Haifa 31905, Israel
    Physiol Plant 139:269-79. 2010
    ..dicoccoides pathosystem. The obtained results also reveal that the distribution of resistance to different pathogen races can be affected by different climatic factors...
  59. ncbi request reprint Microsatellites within genes: structure, function, and evolution
    You Chun Li
    Institute of Evolution, University of Haifa, Haifa, Israel
    Mol Biol Evol 21:991-1007. 2004
    ..These SSRs may provide a molecular basis for fast adaptation to environmental changes in both prokaryotes and eukaryotes...
  60. doi request reprint Genetic diversity and stress of Ricotia lunaria in "Evolution Canyon," Israel
    Olga Kossover
    Institute of Evolution, Department of Evolutionary and Environmental Biology, University of Haifa, Haifa, Israel
    J Hered 100:432-40. 2009
    ..2). Natural selection appears to adaptively diverge the plant ecotypes on the opposite slope, both phenotypically and genotypically. This includes significant divergence in flowering time likely to initiate incipient sympatric speciation...
  61. pmc Quantum speciation in Aegilops: molecular cytogenetic evidence from rDNA cluster variability in natural populations
    Olga Raskina
    Institute of Evolution, University of Haifa, Mt Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 101:14818-23. 2004
    ..speltoides, which make it possible to recognize Ae. sharonensis as a derivative species of Ae. speltoides, as well as to propose rapidness and canalization of quantum speciation in Sitopsis species...
  62. ncbi request reprint Ecological-genomic diversity of microsatellites in wild barley, Hordeum spontaneum, populations in Jordan
    H J Baek
    Institute of Evolution, University of Haifa, Haifa 31905, Israel
    Theor Appl Genet 106:397-410. 2003
    ..362**). These observations suggest that microsatellites are at least partly adaptive and subject to natural selection...
  63. doi request reprint Increases in both acute and chronic temperature potentiate tocotrienol concentrations in wild barley at 'Evolution Canyon'
    Yu Shen
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel, phone 972 4 8240448
    Chem Biodivers 10:1696-705. 2013
    ..The study illustrates the role of α-tocotrienol in both chronic and acute temperature adaptation in wild barley and suggests future research into thermoregulatory mechanisms in plants. ..
  64. pmc Scorpion biodiversity and interslope divergence at "evolution canyon", lower Nahal Oren microsite, Mt. Carmel, Israel
    Shmuel Raz
    Department of Evolutionary and Environmental Biology, University of Haifa, Haifa, Israel
    PLoS ONE 4:e5214. 2009
    ..Scorpions are a suitable taxon to study interslope biodiversity differences, associated with the differences in abiotic factors (climate, drought), due to their ability to adapt to dry environments...
  65. ncbi request reprint Genetic polymorphism of cyanobacteria under permanent natural stress: a lesson from the "Evolution Canyons"
    Volodymyr Dvornyk
    Institute of Evolution, University of Haifa, Mount Carmel, 31905 Haifa, Israel
    Res Microbiol 154:79-84. 2003
    ....
  66. ncbi request reprint Wild barley eibi1 mutation identifies a gene essential for leaf water conservation
    Guoxiong Chen
    Institute of Evolution, University of Haifa, Mount Carmel, 31905, Israel
    Planta 219:684-93. 2004
    ..One may infer that the eibi1 product may reverse the growth inhibition induced by ABA...
  67. ncbi request reprint Increased blood vessel density provides the mole rat physiological tolerance to its hypoxic subterranean habitat
    Aaron Avivi
    Laboratory of Animals Molecular Evolution, Institute of Evolution, University of Haifa, Mt Carmel, Haifa 31905, Israel
    FASEB J 19:1314-6. 2005
    ..The significance of these results with respect to ischemic vascular disease is abundantly clear...
  68. pmc Cloning, expression, and characterization of an alternatively spliced variant of human heparanase
    Nicola J Nasser
    Institute of Evolution, International Graduate Center of Evolution, University of Haifa, Haifa 31905, Israel
    Biochem Biophys Res Commun 354:33-8. 2007
    ..Splice 5 escaped proteolytic cleavage, was devoid of HS degradation activity and exhibited diffused rather than granular cellular localization...
  69. doi request reprint Divergent diversity patterns of NBS and LRR domains of resistance gene analogs in wild emmer wheat populations
    Hanan Sela
    Department of Evolutionary and Environmental Biology, Institute of Evolution, Faculty of Science and Science Education, University of Haifa, Mt Carmel, Haifa, 31905 Israel
    Genome 52:557-65. 2009
    ..The evolutionary and applicative inferences of these findings are discussed. The current study demonstrates that RGA profiling is an excellent tool for studying diversity of R genes in natural plant populations...
  70. ncbi request reprint Sequence polymorphism of candidate behavioural genes in Drosophila melanogaster flies from 'Evolution canyon'
    I Zamorzaeva
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Mol Ecol 14:3235-45. 2005
    ..n = 20), as well as between males originated from the opposing slopes. Females from SFS were less discriminating and did not manifest significant deviation from random mating...
  71. pmc Evolutionary regulation of the blind subterranean mole rat, Spalax, revealed by genome-wide gene expression
    L I Brodsky
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 102:17047-52. 2005
    ..The present results confirm ecologic-genomic separation of blind mole rats into N and S. Gene expression regulation appears to be central to the evolution of blind mole rats...
  72. pmc Is evolution of blind mole rats determined by climate oscillations?
    Yarin Hadid
    Department of Evolutionary and Environmental Biology and Institute of Evolution, University of Haifa, Haifa, Israel
    PLoS ONE 7:e30043. 2012
    ..At the given scale, our results supports the "Court Jester" hypothesis over the "Red Queen" one...
  73. doi request reprint 'Tocol-omic' diversity in wild barley, short communication
    Yu Shen
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel
    Chem Biodivers 8:2322-30. 2011
    ....
  74. pmc Circadian genes in a blind subterranean mammal II: conservation and uniqueness of the three Period homologs in the blind subterranean mole rat, Spalax ehrenbergi superspecies
    Aaron Avivi
    Laboratory of Animal Molecular Evolution, Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 99:11718-23. 2002
    ....
  75. ncbi request reprint Oxygen and carbon dioxide fluctuations in burrows of subterranean blind mole rats indicate tolerance to hypoxic-hypercapnic stresses
    Imad Shams
    Laboratory of Animal Molecular Evolution, Institute of Evolution, University of Haifa, Mt Carmel, Haifa 31905, Israel
    Comp Biochem Physiol A Mol Integr Physiol 142:376-82. 2005
    ....
  76. ncbi request reprint Predictive validity of discriminant analysis for genetic data
    Alex Beharav
    Institute of Evolution, University of Haifa, Mt Carmel, Haifa 31905, Israel
    Genetica 119:259-67. 2003
    ..The results strengthen and support our conclusion and lead us to focus on the discriminant analysis by selecting only low numbers of discriminating variables...
  77. ncbi request reprint Assortative mating in Drosophila adapted to a microsite ecological gradient
    Shree Ram Singh
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Behav Genet 35:753-64. 2005
    ..Genetic heterogeneity in mate choice was found among the isofemale lines of D. melanogaster. Samples of isofemale lines established from females collected in spring and fall seasons show the same mating patterns...
  78. pmc Neuroglobin, cytoglobin, and myoglobin contribute to hypoxia adaptation of the subterranean mole rat Spalax
    Aaron Avivi
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 107:21570-5. 2010
    ..This is consistent with the proposed cytoprotective effect of Ngb and Cygb under pathological hypoxic/ischemic conditions in mammals...
  79. ncbi request reprint Microsatellites: genomic distribution, putative functions and mutational mechanisms: a review
    You Chun Li
    Institute of Evolution, University of Haifa, Haifa 31905, Israel
    Mol Ecol 11:2453-65. 2002
    ..This review also discusses the role of two putative mutational mechanisms, replication slippage and recombination, and their interaction in SSR variation...
  80. pmc Hypoxic stress tolerance of the blind subterranean mole rat: expression of erythropoietin and hypoxia-inducible factor 1 alpha
    Imad Shams
    Laboratory of Animal Molecular Evolution, Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 101:9698-703. 2004
    ..We suggest that this pattern of Epo and HIF-1 alpha expression is a substantial contribution to the adaptive strategy of hypoxia tolerance in Spalax, evolved during 40 million years of evolution to cope with underground hypoxic stress...
  81. ncbi request reprint Mosaic microecological differential stress causes adaptive microsatellite divergence in wild barley, Hordeum spontaneum, at Neve Yaar, Israel
    Qingyang Huang
    Institute of Evolution, University of Haifa, Haifa, 31905, Israel
    Genome 45:1216-29. 2002
    ..The pattern of other SSR loci suggests the operation of balancing selection. SSRs may be either direct targets of selection or markers of selected haplotypes (selective sweep)...
  82. ncbi request reprint Sexual differences for emigration behavior in natural populations of Drosophila melanogaster
    Konstantin G Iliadi
    Institute of Evolution, University of Haifa, Mount Carmel, Israel
    Behav Genet 32:173-80. 2002
    ....
  83. ncbi request reprint The mode of reproduction in natural populations of ascomycetous fungus, Emericella nidulans, from Israel
    E Hosid
    Institute of Evolution, Department of Evolutionary and Environmental Biology, University of Haifa, Mt Carmel, Haifa 31905, Israel
    Genet Res (Camb) 92:83-90. 2010
    ..Increasing sexuality in E. nidulans populations on the north-facing slopes of the northern canyons may be a result of biotic stress (pressure of competitive fungal species), due to the more mild ecological conditions in these canyons...
  84. ncbi request reprint P53 in blind subterranean mole rats--loss-of-function versus gain-of-function activities on newly cloned Spalax target genes
    A Avivi
    Laboratory of Animal Molecular Evolution, Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel
    Oncogene 26:2507-12. 2007
    ..We conclude that Spalax evolved hypoxia-adaptive mechanisms, analogous to the alterations acquired by cancer cells during tumor development, with a bias against apoptosis while favoring cell arrest and DNA repair...
  85. doi request reprint Discrimination of 2n = 60 Spalax leucodon cytotypes (Spalacidae, Rodentia) in Turkey by means of classical and molecular cytogenetic techniques
    E Ivanitskaya
    Institute of Evolution, University of Haifa, Haifa, Israel
    Cytogenet Genome Res 122:139-49. 2008
    ..Our findings suggest a high level of chromosomal divergence, which means that it is possible to consider these cytotypes as a well-differentiated, chromosomal lineage within the leucodon group...
  86. doi request reprint Repetitive DNA and chromosomal rearrangements: speciation-related events in plant genomes
    O Raskina
    Institute of Evolution, University of Haifa, Israel
    Cytogenet Genome Res 120:351-7. 2008
    ....
  87. ncbi request reprint Different clustering of genomes across life using the A-T-C-G and degenerate R-Y alphabets: early and late signaling on genome evolution?
    V Kirzhner
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel
    J Mol Evol 64:448-56. 2007
    ....
  88. ncbi request reprint Adaptive differentiation of thermotolerance in Drosophila along a microclimatic gradient
    E Rashkovetsky
    Institute of Evolution, The University of Haifa, Mt Carmel, Haifa 31905, Israel
    Heredity (Edinb) 96:353-9. 2006
    ..Inbred lines, however, had lower thermotolerance than outbred lines. Several nonexclusive processes may explain the evolution of such physiological differentiation...
  89. ncbi request reprint Variability of the chromosomal distribution of Ty3-gypsy retrotransposons in the populations of two wild Triticeae species
    A Belyayev
    Institute of Evolution, University of Haifa, Mt Carmel, Haifa, Israel
    Cytogenet Genome Res 109:43-9. 2005
    ..speltoides genome contrasts with the uniform genome of H. spontaneum and may reflect differences in adaptive strategies between investigated species...
  90. ncbi request reprint The lens protein alpha-B-crystallin of the blind subterranean mole-rat: high homology with sighted mammals
    A Avivi
    Laboratory of Molecular Evolution of Animals, Institute of Evolution, University of Haifa, Mt Carmel, 31905, Haifa, Israel
    Gene 264:45-9. 2001
    ..The sequence of the cDNA of alpha-B-Crystallin in the eye and in the heart of Spalax is identical. Further studies are essential to clarify the role of this gene in the lens of an atrophied eye of a visually blind mammal...
  91. ncbi request reprint Chromosomal distribution of reverse transcriptase-containing retroelements in two Triticeae species
    A Belyayev
    Institute of Evolution, Haifa University, Mt Carmel, Israel
    Chromosome Res 9:129-36. 2001
    ..We found that there was a predominance of Ty1-copia and LINE elements in the chromosome regions with preferential content of species-specific sequences...
  92. ncbi request reprint Evolutionary dynamics and chromosomal distribution of repetitive sequences on chromosomes of Aegilops speltoides revealed by genomic in situ hybridization
    A Belyayev
    Institute of Evolution, Haifa University, Mt Carmel, Haifa, 31905 Israel
    Heredity (Edinb) 86:738-42. 2001
    ..GISH experiments revealed extensive conservation in NOR regions on chromosomes 1 and 6 which, in fact, appears to be a complicated mix of rDNA clusters and heterochromatin blocks of different nucleotide composition...
  93. pmc Sexual and reproductive behaviour of Drosophila melanogaster from a microclimatically interslope differentiated population of "Evolution Canyon" (Mount Carmel, Israel)
    K Iliadi
    Pavlov Institute of Physiology, Russian Academy of Sciences, St Petersburg 199034, Russia
    Proc Biol Sci 268:2365-74. 2001
    ..These patterns represent adaptive life strategies contributing to higher fitness...
  94. pmc Biological clock in total darkness: the Clock/MOP3 circadian system of the blind subterranean mole rat
    A Avivi
    Institute of Evolution, University of Haifa, Mount Carmel, Haifa 31905, Israel
    Proc Natl Acad Sci U S A 98:13751-6. 2001
    ..Understanding Clock/MOP3 function could highlight circadian mechanisms in blind mammals and their unique pattern as a result of adapting to life underground...
  95. pmc Constructing large-scale genetic maps using an evolutionary strategy algorithm
    D Mester
    Institute of Evolution, University of Haifa, Haifa 31905, Israel
    Genetics 165:2269-82. 2003
    ..Parallel calculation technology can easily be adopted for further acceleration of the proposed algorithm. Real data analysis (on maize chromosome 1 with 230 markers) is provided to illustrate the proposed methodology...
  96. pmc Enhanced efficiency of quantitative trait loci mapping analysis based on multivariate complexes of quantitative traits
    A B Korol
    Institute of Evolution, University of Haifa, Haifa 31905, Israel
    Genetics 157:1789-803. 2001
    ..An example of application of the proposed method on a real data set of 11 traits from an experiment performed on an F(2)/F(3) mapping population of tetraploid wheat (Triticum durum x T. dicoccoides) is provided...
  97. ncbi request reprint Detection of alien chromosomes from S-genome species in the addition/substitution lines of bread wheat and visualization of A-, B- and D-genomes by GISH
    A Belyayev
    Institute of Evolution, Haifa University, Mt Carmel, Haifa, 31905 Israel
    Hereditas 135:119-22. 2001
    ..As a result, we observed brown chromosomes of A-genome, banded green chromosomes of B-genome and red chromosomes of D-genome. Inter genomic invasion of the sequences from A/B-genomes to D-genome has been detected...
  98. ncbi request reprint Coevolution of A and B genomes in allotetraploid Triticum dicoccoides
    A Belyayev
    Institute of Evolution, Haifa University, Israel
    Genome 43:1021-6. 2000
    ..We propose that the detected high level of intergenomic invasion in old polyploids might reflect general tendencies in speciation and stabilization of the allopolyploid genome...
  99. pmc Ecologic genomics of DNA: upstream bending in prokaryotic promoters
    A Bolshoy
    Institute of Evolution, University of Haifa, Haifa, 31905 Israel
    Genome Res 10:1185-93. 2000
    ..e., DNA curvature presumably has a functional adaptive significance determined by temperature selection...
  100. pmc Approximate analysis of QTL-environment interaction with no limits on the number of environments
    A B Korol
    Institute of Evolution, University of Haifa, Mount Carmel, Israel
    Genetics 148:2015-28. 1998
    ....
  101. ncbi request reprint Heterochromatin differentiation shows the pathways of karyotypic evolution in Israeli mole rats (Spalax, Spalacidae, Rodentia)
    E Ivanitskaya
    Institute of Evolution, University of Haifa, Haifa, Israel
    Cytogenet Genome Res 111:159-65. 2005
    ..Interspecies heterochromatin differences are discussed in the context of possible mechanisms in the Spalax chromosome evolution...