Abraham Zlotogorski

Summary

Affiliation: The Hebrew University
Country: Israel

Publications

  1. ncbi request reprint A model for quantitative measurement of sulfur mustard skin lesions in the rabbit ear
    A Zlotogorski
    Department of Dermatology, Hadassah University Hospital, Jerusalem, Israel
    Toxicology 120:105-10. 1997
  2. ncbi request reprint South American cutaneous leishmaniasis: report of ten cases in Israeli travelers
    A Zlotogorski
    Department of Dermatology, Hadassah University Hospital, Jerusalem, Israel
    J Eur Acad Dermatol Venereol 11:32-6. 1998
  3. ncbi request reprint Monilethrix: a keratin hHb6 mutation is co-dominant with variable expression
    A Zlotogorski
    Department of Dermatology, Hadassah University Hospital, Jerusalem, Israel
    Exp Dermatol 7:268-72. 1998
  4. ncbi request reprint An autosomal recessive form of monilethrix is caused by mutations in DSG4: clinical overlap with localized autosomal recessive hypotrichosis
    Abraham Zlotogorski
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Invest Dermatol 126:1292-6. 2006
  5. ncbi request reprint Clinical and pathologic correlations in genetically distinct forms of atrichia
    Abraham Zlotogorski
    Departments of Dermatology, Hebrew University Hadassah Medical Center, Jerusalem, Israel
    Arch Dermatol 139:1591-6. 2003
  6. doi request reprint The H syndrome: a genodermatosis characterized by indurated, hyperpigmented, and hypertrichotic skin with systemic manifestations
    Vered Molho-Pessach
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Am Acad Dermatol 59:79-85. 2008
  7. pmc The H syndrome is caused by mutations in the nucleoside transporter hENT3
    Vered Molho-Pessach
    Department of Dermatology, Hadassah, Hebrew University Medical Center, Jerusalem 91120, Israel
    Am J Hum Genet 83:529-34. 2008
  8. ncbi request reprint De novo mutations in monilethrix
    Liran Horev
    Department of Dermatology, Hadassah University Medical Center, Jerusalem, Israel
    Exp Dermatol 12:882-5. 2003
  9. doi request reprint Mutations in lipase H cause autosomal recessive hypotrichosis simplex with woolly hair
    Liran Horev
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Am Acad Dermatol 61:813-8. 2009
  10. ncbi request reprint Angiokeratoma corporis diffusum in human beta-mannosidosis: Report of a new case and a novel mutation
    Vered Molho-Pessach
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel
    J Am Acad Dermatol 57:407-12. 2007

Collaborators

Detail Information

Publications43

  1. ncbi request reprint A model for quantitative measurement of sulfur mustard skin lesions in the rabbit ear
    A Zlotogorski
    Department of Dermatology, Hadassah University Hospital, Jerusalem, Israel
    Toxicology 120:105-10. 1997
    ..Consequently, this model can serve as a useful tool for future screening of potential compounds for prevention and treatment of sulfur mustard-induced skin lesions...
  2. ncbi request reprint South American cutaneous leishmaniasis: report of ten cases in Israeli travelers
    A Zlotogorski
    Department of Dermatology, Hadassah University Hospital, Jerusalem, Israel
    J Eur Acad Dermatol Venereol 11:32-6. 1998
    ..Cutaneous South American leishmaniasis is caused by several species of leishmaniasis. Lack of appropriate treatment may lead to mucocutaneous leishmaniasis, mainly with L. b. braziliensis and L. b. panamensis...
  3. ncbi request reprint Monilethrix: a keratin hHb6 mutation is co-dominant with variable expression
    A Zlotogorski
    Department of Dermatology, Hadassah University Hospital, Jerusalem, Israel
    Exp Dermatol 7:268-72. 1998
    ..This represents the first report of a co-dominant keratin hHb6 mutation resulting in severe disease...
  4. ncbi request reprint An autosomal recessive form of monilethrix is caused by mutations in DSG4: clinical overlap with localized autosomal recessive hypotrichosis
    Abraham Zlotogorski
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Invest Dermatol 126:1292-6. 2006
    ..Our findings have important implications for genetic counseling to monilethrix patients and families, and suggest that DSG4-associated hair disorders may be more common than previously thought...
  5. ncbi request reprint Clinical and pathologic correlations in genetically distinct forms of atrichia
    Abraham Zlotogorski
    Departments of Dermatology, Hebrew University Hadassah Medical Center, Jerusalem, Israel
    Arch Dermatol 139:1591-6. 2003
    ..We sought to document the clinical and molecular features of APL and VDDR IIA...
  6. doi request reprint The H syndrome: a genodermatosis characterized by indurated, hyperpigmented, and hypertrichotic skin with systemic manifestations
    Vered Molho-Pessach
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Am Acad Dermatol 59:79-85. 2008
    ....
  7. pmc The H syndrome is caused by mutations in the nucleoside transporter hENT3
    Vered Molho-Pessach
    Department of Dermatology, Hadassah, Hebrew University Medical Center, Jerusalem 91120, Israel
    Am J Hum Genet 83:529-34. 2008
    ..The identification of mutations in the SLC29A3 gene in patients with a mild clinical phenotype suggests that this is a largely underdiagnosed condition and strongly suggests that even oligosymptomatic individuals might have the disorder...
  8. ncbi request reprint De novo mutations in monilethrix
    Liran Horev
    Department of Dermatology, Hadassah University Medical Center, Jerusalem, Israel
    Exp Dermatol 12:882-5. 2003
    ..In five patients no mutations were found, while in two patients we identified de novo germline missense mutations at the helix termination motif: E402K (hHb6) and E413K (hHb1)...
  9. doi request reprint Mutations in lipase H cause autosomal recessive hypotrichosis simplex with woolly hair
    Liran Horev
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Am Acad Dermatol 61:813-8. 2009
    ..Mutations in lipase H (LIPH) are a rare cause of autosomal recessive hypotrichosis (HT) simplex...
  10. ncbi request reprint Angiokeratoma corporis diffusum in human beta-mannosidosis: Report of a new case and a novel mutation
    Vered Molho-Pessach
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel
    J Am Acad Dermatol 57:407-12. 2007
    ..So far, mutational analysis has been performed in only seven families and revealed 11 mutations in the MANBA gene which encodes the enzyme beta-mannosidase...
  11. doi request reprint Early-onset sensorineural hearing loss is a prominent feature of H syndrome
    Yuval Ramot
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Int J Pediatr Otorhinolaryngol 74:825-7. 2010
    ..The aim of this paper is to increase awareness to this recently described disorder, and to emphasize that H syndrome should be included in the differential diagnosis of congenital or acquired syndromic hearing loss in children...
  12. doi request reprint Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature syndrome: a case report
    Yuval Ramot
    Departments of Dermatology, The Center for Genetic Diseases of the Skin and Hair, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Pediatr Dermatol 28:538-41. 2011
    ..This syndrome may represent a new autosomal recessive auto-inflammatory genodermatosis. Increased awareness may lead to the discovery of more cases, and clarify its pathogenesis...
  13. ncbi request reprint Evidence for pseudodominant inheritance of atrichia with papular lesions
    Abraham Zlotogorski
    Department of Dermatology, Hadassah University Medical Center, Jerusalem, Israel
    J Invest Dermatol 118:881-6. 2002
    ....
  14. ncbi request reprint Clinical and molecular diagnostic criteria of congenital atrichia with papular lesions
    Abraham Zlotogorski
    Department of Dermatology, Hadassah Medical Center, Jerusalem, Israel
    J Invest Dermatol 118:887-90. 2002
    ..Collectively, we anticipate that an increased recognition of this disorder will result in more accurate diagnosis and the sparing of unnecessarily treatment to patients...
  15. ncbi request reprint Evidence for clinical and genetic heterogeneity in hereditary benign telangiectasia
    Vered Molho-Pessach
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Am Acad Dermatol 57:814-8. 2007
    ..The disorder has been previously mapped to a 7Mb interval on chromosome 5q14 (CMC1 locus) in an Italian pedigree with randomly distributed telangiectases...
  16. ncbi request reprint A novel splice-site mutation in ECM-1 gene in a consanguineous family with lipoid proteinosis
    Liran Horev
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Exp Dermatol 14:891-7. 2005
    ..This case further emphasizes the role of ECM-1 in LP and highlights the unresolved genotype-phenotype correlation in this disease...
  17. doi request reprint H syndrome: The first 79 patients
    Vered Molho-Pessach
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel Center for Genetic Diseases of the Skin and Hair, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Am Acad Dermatol 70:80-8. 2014
    ..H syndrome is an autosomal recessive genodermatosis with multisystem involvement caused by mutations in SLC29A3...
  18. doi request reprint The spectrum of radiological findings in H syndrome
    Nurith Hiller
    Department of Radiology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Clin Imaging 37:313-9. 2013
    ..To describe the spectrum of radiological findings in 12 patients with H syndrome...
  19. doi request reprint A case of H syndrome showing immunophenotye similarities to Rosai-Dorfman disease
    Emily Avitan-Hersh
    Departments of Dermatology, Technion Institute of Technology, Haifa, Israel
    Am J Dermatopathol 33:47-51. 2011
    ....
  20. doi request reprint Regrowth of black hair in two red-haired alopecia areata patients
    Yuval Ramot
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Australas J Dermatol 53:e91-2. 2012
    ..This phenomenon raises some interesting questions regarding the significance of pigmentation and the melanocortin-1 receptor in AA pathogenesis...
  21. doi request reprint Endocrine controls of keratin expression
    Yuval Ramot
    Department of Dermatology, Hadassah Hebrew University Medical Center, and the Center for Genetic Diseases of the Skin and Hair, Jerusalem, Israel
    Bioessays 31:389-99. 2009
    ....
  22. ncbi request reprint Quality improvement program to assure the delivery of pathology test results: a systemic intervention in a large general hospital
    Pnina Topol
    Dermatology Clinic, Hadassah University Medical Center, Jerusalem, Israel
    Dermatol Nurs 19:253-7. 2007
    ..Theses two outcomes improved significantly after the intervention. This study demonstrates how nurses can play a major role in both patient and staff education and with performing organizational chance to strengthen patient safety...
  23. doi request reprint H syndrome: recently defined genodermatosis with distinct histologic features. A morphological, histochemical, immunohistochemical, and ultrastructural study of 10 cases
    Victoria Doviner
    Department of Pathology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Am J Dermatopathol 32:118-28. 2010
    ..We conclude that the above findings are essential for the diagnosis of H syndrome and that incisional biopsies are mandatory for recognition of the full spectrum of histopathological findings...
  24. pmc An extraordinary colocalization of alopecia areata and vitiligo
    Yuval Ramot
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Int J Trichology 2:108-9. 2010
    ....
  25. pmc Phenotypic variability among adult siblings with Sjögren-Larsson syndrome
    Alexander Lossos
    Department of Neurology, Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Arch Neurol 63:278-80. 2006
    ..Cerebral proton magnetic resonance spectroscopy in those with SLS demonstrates an abnormal white matter peak at 1.3 ppm, consistent with long-chain fatty alcohol accumulation...
  26. pmc Atypical "allergic crease"
    Yuval Ramot
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Dermatol Case Rep 4:36-7. 2010
    ..Considering the fact that allergic rhinitis is a common chronic condition of childhood, increased awareness of the skin manifestations which accompany this condition is essential...
  27. doi request reprint Emperipolesis: an additional common histopathologic finding in H syndrome and Rosai-Dorfman disease
    Isabel Colmenero
    Department of Pathology, Hospital del Nino Jesus, Madrid, Spain
    Am J Dermatopathol 34:315-20. 2012
    ..We describe emperipolesis in the cutaneous lesions of a patient with H syndrome, further supporting the relationship between Rosai-Dorfman disease and H syndrome...
  28. pmc Finasteride induced Gynecomastia: Case report and Review of the Literature
    Yuval Ramot
    Department of Dermatology, Hadassah Hebrew University Medical Center, Jerusalem 912 00, Israel
    Int J Trichology 1:27-9. 2009
    ..Although relatively rare, physicians should be aware of this side effect and inform their patients when prescribing this medication...
  29. ncbi request reprint Compound heterozygous mutations in the hairless gene in atrichia with papular lesions
    Amy S Paller
    J Invest Dermatol 121:430-2. 2003
  30. ncbi request reprint Localized autosomal recessive hypotrichosis due to a frameshift mutation in the desmoglein 4 gene exhibits extensive phenotypic variability within a Pakistani family
    Muhammad Wajid
    J Invest Dermatol 127:1779-82. 2007
  31. ncbi request reprint Interaction of hairless and thyroid hormone receptor is not involved in the pathogenesis of atrichia with papular lesions
    Karima Djabali
    Departments of Dermatology and Genetics and Development, Columbia University, New York, NY 10032, USA
    Exp Dermatol 13:251-6. 2004
    ..This result suggests that the TRID2 domain either is dispensable in the hr-TR interaction or is not involved in the pathogenesis of APL...
  32. ncbi request reprint Germline fumarate hydratase mutations in families with multiple cutaneous and uterine leiomyomata
    Amalia Martinez-Mir
    Department of Dermatology, Columbia University, New York, New York, USA
    J Invest Dermatol 121:741-4. 2003
    ..These results provide further evidence for the role of the FH gene in the pathogenesis of MCL...
  33. ncbi request reprint Evidence for extensive locus heterogeneity in Naxos disease
    Karima Djabali
    J Invest Dermatol 118:557-60. 2002
  34. ncbi request reprint Multiple cutaneous and uterine leiomyomas: refinement of the genetic locus for multiple cutaneous and uterine leiomyomas on chromosome 1q42.3-43
    Amalia Martinez-Mir
    Department of Dermatology, Columbia University, New York, New York, USA
    J Invest Dermatol 118:876-80. 2002
    ....
  35. ncbi request reprint Search for susceptibility genes in alopecia areata
    Amalia Martinez-Mir
    Department of Dermatology, Columbia University, New York, New York, USA
    J Investig Dermatol Symp Proc 10:281-2. 2005
  36. ncbi request reprint Atrichia with papular lesions resulting from novel compound heterozygous mutations in the human hairless gene
    Eleni Michailidis
    College of Dental Medicine, Columbia University, New York, New York, USA
    Pediatr Dermatol 24:E79-82. 2007
    ..These novel mutations add to the growing literature of mutations in the hairless gene found in nonconsanguineous families and expands the allelic series of mutations in this gene...
  37. pmc Genomewide scan for linkage reveals evidence of several susceptibility loci for alopecia areata
    Amalia Martinez-Mir
    Department of Dermatology, Columbia University, New York, NY 10032, USA
    Am J Hum Genet 80:316-28. 2007
    ..Interestingly, the major loci on chromosomes 16 and 18 coincide with loci for psoriasis reported elsewhere. These results suggest that these regions may harbor gene(s) involved in a number of different skin and hair disorders...
  38. ncbi request reprint Atrichia with papular lesions resulting from compound heterozygous mutations in the hairless gene: A lesson for differential diagnosis of alopecia universalis
    Wolfram Henn
    Institute of Human Genetics, Saarland University, Homburg Saar, Germany
    J Am Acad Dermatol 47:519-23. 2002
    ..Atrichia with papular lesions (APL) is a rare, autosomal recessive form of total alopecia in which mutations in the hairless (HR) gene have been shown to underlie the phenotype...
  39. ncbi request reprint Novel compound heterozygous nonsense mutations in the hairless gene causing atrichia with papular lesions
    Ghalia G Ashoor
    Genetic Skin Disease Group, St John s Institute of Dermatology, The Guy s King s College and St Thomas Hospital Medical School, London, UK
    J Dermatol Sci 40:29-33. 2005
    ..Atrichia with papular lesions (APL) is a rare autosomal recessive condition resulting from mutations in the hairless (HR) gene...
  40. doi request reprint Atrichia with papular lesions: a report of three novel human hairless gene mutations and a revision of diagnostic criteria
    Leona Yip
    Department of Dermatology, Skin and Cancer Foundation of Victoria, St Vincent s Hospital Melbourne, Victoria, Australia
    Acta Derm Venereol 88:346-9. 2008
    ..We also revise the diagnostic criteria for atrichia with papular lesions in order to clarify its uniqueness and distinguishing features from alopecia universalis...
  41. ncbi request reprint Morphological approach to hair disorders
    Rodney Sinclair
    Department of Dermatology, University of Melbourne, Victoria, Australia
    J Investig Dermatol Symp Proc 8:56-64. 2003
    ..The final section by Leroy and Van Neste highlights the difficulties of evaluating therapeutic interventions in hair loss disease and proposes a new technique...
  42. ncbi request reprint Germline fumarate hydratase mutations and evidence for a founder mutation underlying multiple cutaneous and uterine leiomyomata
    Gary S Chuang
    Department of Dermatology, Columbia University, New York, New York, USA
    J Am Acad Dermatol 52:410-6. 2005
    ..Collectively, identification of 5 novel and 3 recurrent mutations further supports the role of FH in the pathogenesis of MCL...
  43. ncbi request reprint A nonsense mutation in the desmoglein 1 gene underlies striate keratoderma
    Ana Kljuic
    Department of Genetics and Development, Columbia University, New York, NY, USA
    Exp Dermatol 12:523-7. 2003
    ..The mutation identified in this study is a novel mutation in the DSG1 gene and extends the body of evidence implicating the desmoglein gene family in the pathogenesis of human skin disorders...