Charles L Sprung

Summary

Affiliation: The Hebrew University
Country: Israel

Publications

  1. ncbi Implications of ICU triage decisions on patient mortality: a cost-effectiveness analysis
    David L Edbrooke
    Medical and Economics Research Centre Sheffield, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, Sheffield S10 2JF, UK
    Crit Care 15:R56. 2011
  2. ncbi Insulin-treated diabetes is not associated with increased mortality in critically ill patients
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Universite Libre de Bruxelles, Route de Lennik 808, 1070 Bruxelles, Belgium
    Crit Care 14:R12. 2010
  3. ncbi Characteristics and outcomes of cancer patients in European ICUs
    Fabio Silvio Taccone
    Department of Intensive Care, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Crit Care 13:R15. 2009
  4. ncbi Global utilization of low-dose corticosteroids in severe sepsis and septic shock: a report from the PROGRESS registry
    Richard Beale
    Division of Asthma, King s College London, Guy s, Campus, Great Maze Pond, London SE1 9RT, UK
    Crit Care 14:R102. 2010
  5. ncbi Is albumin administration in the acutely ill associated with increased mortality? Results of the SOAP study
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Free University of Brussels, Route de Lennik 808, 1070 Brussels, Belgium
    Crit Care 9:R745-54. 2005
  6. ncbi The importance of religious affiliation and culture on end-of-life decisions in European intensive care units
    Charles L Sprung
    General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Medical Center, Hadassah Hebrew University, P O Box 12000, 91120, Jerusalem, Israel
    Intensive Care Med 33:1732-9. 2007
  7. ncbi Reasons, considerations, difficulties and documentation of end-of-life decisions in European intensive care units: the ETHICUS Study
    Charles L Sprung
    Hadassah Hebrew University Medical Center, General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, P O Box 12000, 91120 Jerusalem, Israel
    Intensive Care Med 34:271-7. 2008
  8. ncbi An evaluation of systemic inflammatory response syndrome signs in the Sepsis Occurrence In Acutely Ill Patients (SOAP) study
    Charles L Sprung
    Hadassah Hebrew University, Medical Center, Department of Anaesthesiology and Critical Care Medicine, P O Box 1200, 91120, Jerusalem, Israel
    Intensive Care Med 32:421-7. 2006
  9. ncbi Hydrocortisone therapy for patients with septic shock
    Charles L Sprung
    Hadassah Hebrew University Medical Center, Jerusalem, Israel 91120
    N Engl J Med 358:111-24. 2008
  10. ncbi Relieving suffering or intentionally hastening death: where do you draw the line?
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 36:8-13. 2008

Detail Information

Publications70

  1. ncbi Implications of ICU triage decisions on patient mortality: a cost-effectiveness analysis
    David L Edbrooke
    Medical and Economics Research Centre Sheffield, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, Sheffield S10 2JF, UK
    Crit Care 15:R56. 2011
    ....
  2. ncbi Insulin-treated diabetes is not associated with increased mortality in critically ill patients
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Universite Libre de Bruxelles, Route de Lennik 808, 1070 Bruxelles, Belgium
    Crit Care 14:R12. 2010
    ..This was a planned substudy from the European observational Sepsis Occurrence in Acutely ill Patients (SOAP) study to investigate the possible impact of insulin-treated diabetes on morbidity and mortality in ICU patients...
  3. ncbi Characteristics and outcomes of cancer patients in European ICUs
    Fabio Silvio Taccone
    Department of Intensive Care, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Crit Care 13:R15. 2009
    ..The aim of this study was to assess the characteristics of critically ill cancer patients, and to evaluate their prognosis...
  4. ncbi Global utilization of low-dose corticosteroids in severe sepsis and septic shock: a report from the PROGRESS registry
    Richard Beale
    Division of Asthma, King s College London, Guy s, Campus, Great Maze Pond, London SE1 9RT, UK
    Crit Care 14:R102. 2010
    ....
  5. ncbi Is albumin administration in the acutely ill associated with increased mortality? Results of the SOAP study
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Free University of Brussels, Route de Lennik 808, 1070 Brussels, Belgium
    Crit Care 9:R745-54. 2005
    ..Albumin administration in the critically ill has been the subject of some controversy. We investigated the use of albumin solutions in European intensive care units (ICUs) and its relationship to outcome...
  6. ncbi The importance of religious affiliation and culture on end-of-life decisions in European intensive care units
    Charles L Sprung
    General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Medical Center, Hadassah Hebrew University, P O Box 12000, 91120, Jerusalem, Israel
    Intensive Care Med 33:1732-9. 2007
    ..To determine the influence of religious affiliation and culture on end-of-life decisions in European intensive care units (ICUs)...
  7. ncbi Reasons, considerations, difficulties and documentation of end-of-life decisions in European intensive care units: the ETHICUS Study
    Charles L Sprung
    Hadassah Hebrew University Medical Center, General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, P O Box 12000, 91120 Jerusalem, Israel
    Intensive Care Med 34:271-7. 2008
    ..To evaluate physicians' reasoning, considerations and possible difficulties in end-of-life decision-making for patients in European intensive care units (ICUs)...
  8. ncbi An evaluation of systemic inflammatory response syndrome signs in the Sepsis Occurrence In Acutely Ill Patients (SOAP) study
    Charles L Sprung
    Hadassah Hebrew University, Medical Center, Department of Anaesthesiology and Critical Care Medicine, P O Box 1200, 91120, Jerusalem, Israel
    Intensive Care Med 32:421-7. 2006
    ..To define the frequency and prognostic implications of SIRS criteria in critically ill patients hospitalized in European ICUs...
  9. ncbi Hydrocortisone therapy for patients with septic shock
    Charles L Sprung
    Hadassah Hebrew University Medical Center, Jerusalem, Israel 91120
    N Engl J Med 358:111-24. 2008
    ....
  10. ncbi Relieving suffering or intentionally hastening death: where do you draw the line?
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 36:8-13. 2008
    ..End-of-life practices vary worldwide. The objective was to demonstrate that there is no clear-cut distinction between treatments administered to relieve pain and suffering and those intended to shorten the dying process...
  11. ncbi Peter Sjokvist
    Charles L Sprung
    General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, PO Box 12000, 91120 Jerusalem, Israel
    Intensive Care Med 30:1250-1. 2004
  12. ncbi Steroid therapy of septic shock
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Clin 25:825-34, x. 2009
    ..It reviews and contrasts several low- and high-dose steroid studies, and makes recommendations for future practice...
  13. ncbi Steroid therapy of septic shock
    Charles L Sprung
    General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Nurs Clin North Am 23:171-80. 2011
    ..Finally, steroid therapy should not be guided by corticotropin test results...
  14. ncbi Attitudes of European physicians, nurses, patients, and families regarding end-of-life decisions: the ETHICATT study
    Charles L Sprung
    General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, PO Box 12000, 91120, Jerusalem, Israel
    Intensive Care Med 33:104-10. 2007
    ..To evaluate attitudes of Europeans regarding end-of-life decisions...
  15. ncbi Effect of infections on 30-day mortality among critically ill patients hospitalized in and out of the intensive care unit
    George Mnatzaganian
    Department of Health Services Research, Ministry of Health, Jerusalem, Israel
    Crit Care Med 36:1097-104. 2008
    ..This analysis is part of a multicenter study conducted in Israel to evaluate survival of critically ill patients treated in and out of intensive care units (ICUs)...
  16. ncbi Nurse involvement in end-of-life decision making: the ETHICUS Study
    Julie Benbenishty
    Hadassah Medical Organization, Jerusalem, Israel
    Intensive Care Med 32:129-32. 2006
    ..Once a decision is made, there is a sense of agreement. The level of perceived participation is different for different regions...
  17. ncbi The Eldicus prospective, observational study of triage decision making in European intensive care units. Part II: intensive care benefit for the elderly
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 40:132-8. 2012
    ..Life and death triage decisions are made daily by intensive care unit physicians. Admission to an intensive care unit is denied when intensive care unit resources are constrained, especially for the elderly...
  18. ncbi Chapter 5. Essential equipment, pharmaceuticals and supplies. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Intensive Care Med 36:S38-44. 2010
    ..To provide recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza pandemic or mass disaster with a specific focus on essential equipment, pharmaceuticals and supplies...
  19. ncbi Survival of critically ill patients hospitalized in and out of intensive care
    Elisheva Simchen
    Department of Health Services Research, Ministry of Health, Jerusalem, Israel
    Crit Care Med 35:449-57. 2007
    ..The survival of such patients is largely unknown. The present study's objective was to screen entire hospitals for newly deteriorated patients and compare their survival in and out of the intensive care unit...
  20. ncbi Recommendations for intensive care unit and hospital preparations for an influenza epidemic or mass disaster: summary report of the European Society of Intensive Care Medicine's Task Force for intensive care unit triage during an influenza epidemic or mas
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Intensive Care Med 36:428-43. 2010
    ..To provide recommendations and standard operating procedures for intensive care units and hospital preparedness for an influenza pandemic...
  21. ncbi Conventional terrorist bomb incidents and the intensive care unit
    Micha Y Shamir
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University School of Medicine, Hadassah Medical Organization, Jerusalem, Israel
    Curr Opin Crit Care 11:580-4. 2005
    ..This information should aid in rational crisis planning...
  22. ncbi Cortisol changes among patients with septic shock and the relationship to ICU and hospital stay
    Sergei Goodman
    Department of Anesthesiology and Critical Care Medicine, Hadassah University Hospital, Hadassah Medical School, Hebrew University, P.O.B. 12000, 91120 Jerusalem, Israel
    Intensive Care Med 31:1362-9. 2005
    ..The proportional change between unstimulated cortisol and post-ACTH cortisol was used as a method to evaluate the relative change in cortisol levels between patients...
  23. ncbi Evaluation of changes in forgoing life-sustaining treatment in Israeli ICU patients
    Daniel J Jakobson
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, The Hebrew University of Jerusalem, PO Box 12000, Jerusalem, Israel 91120, USA
    Chest 126:1969-73. 2004
    ....
  24. ncbi End-of-life practices in European intensive care units: the Ethicus Study
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    JAMA 290:790-7. 2003
    ....
  25. ncbi Diastolic dysfunction and mortality in severe sepsis and septic shock
    Giora Landesberg
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel
    Eur Heart J 33:895-903. 2012
    ..In contrast, diastolic dysfunction is often ignored and its role in determining early mortality from sepsis has not been adequately investigated...
  26. ncbi The Eldicus prospective, observational study of triage decision making in European intensive care units: part I--European Intensive Care Admission Triage Scores
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 40:125-31. 2012
    ..The objective of this study was to develop an intensive care unit triage decision rule based on 28-day mortality rates of admitted and refused patients...
  27. ncbi Intensive care physicians' attitudes concerning distribution of intensive care resources. A comparison of Israeli, North American and European cohorts
    Sharon Einav
    Department of Anesthesiology and Critical Care Medicine, Hadassah Medical Center, Hebrew University of Jerusalem, POB 12000, 91120 Jerusalem, Israel
    Intensive Care Med 30:1140-3. 2004
    ..To evaluate the attitudes of Israeli intensive care physicians regarding intensive care unit (ICU) triage issues...
  28. ncbi Clinical review: the Israeli experience: conventional terrorism and critical care
    Gabriella Aschkenasy-Steuer
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University School of Medicine, Hadassah Medical Organization, Jerusalem, Israel
    Crit Care 9:490-9. 2005
    ..This review emphasizes the importance of a multidisciplinary team approach in caring for these patients...
  29. ncbi End-of-life treatment and bacterial antibiotic resistance: a potential association
    Phillip D Levin
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Chest 138:588-94. 2010
    ..Great variability exists in the occurrence of antibiotic-resistant bacteria in ICUs around the world. The contribution of specific ICU care variables to these geographic variations is unknown...
  30. ncbi Blood cultures at central line insertion in the intensive care unit: comparison with peripheral venipuncture
    Sheldon Stohl
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Centre, POB 12000, Jerusalem 91120, Israel
    J Clin Microbiol 49:2398-403. 2011
    ..This may be related to the increased manipulations required for CVC insertion...
  31. ncbi The dying patient act, 2005: Israeli innovative legislation
    Avraham Steinberg
    Medical Ethics Unit and Department of Pediatrics, Shaare Zedek Medical Center, Jerusalem, Israel
    Isr Med Assoc J 9:550-2. 2007
    ....
  32. ncbi Assessing the in-hospital survival benefits of intensive care
    Amir Shmueli
    Department of Health Management, The Hebrew University, Jerusalem, Israel
    Int J Technol Assess Health Care 21:66-72. 2005
    ..The objective of this study is to assess the differential survival benefits of a general intensive care unit (ICU) by acute diagnoses and by Acute Physiological and Chronic Health Evaluation (APACHE II) scores...
  33. ncbi Caring for a major government official: challenges and lessons learned
    Yoram G Weiss
    Departments of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 35:1769-72. 2007
    ..This article presents a strategy for addressing these issues...
  34. ncbi End-of-life intensive care unit decisions, communication, and documentation: an evaluation of physician training
    Leonid A Eidelman
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, The Hebrew University of Jerusalem, Jerusalem, Israel
    J Crit Care 18:11-6. 2003
    ..Communication between physicians, patients, and their families regarding the decision to FLST has not been evaluated in Israel...
  35. ncbi Antimicrobial use in the ICU: indications and accuracy--an observational trial
    Phillip D Levin
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Hosp Med 7:672-8. 2012
    ..Antimicrobials may therefore be overused, contributing to development of antimicrobial-resistant bacteria...
  36. ncbi Improved ICU design reduces acquisition of antibiotic-resistant bacteria: a quasi-experimental observational study
    Phillip D Levin
    Department of Anesthesia and Critical Care, Hadassah Hebrew University Medical Center, POB 12000, Jerusalem 91120, Israel
    Crit Care 15:R211. 2011
    ..The role of ICU design and particularly single-patient rooms in decreasing bacterial transmission between ICU patients has been debated. A recent change in our ICU allowed further investigation...
  37. ncbi Characteristics of patients receiving vasopressors
    Julie Benbenishty
    Department of Anesthesia and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Heart Lung 40:247-52. 2011
    ..Patients receiving intensive care frequently need pharmacologic support of their blood pressure because of shock. In some patients, shock is so severe that extremely high doses of vasopressors are needed to elevate their blood pressure...
  38. ncbi Survival of critically ill patients hospitalized in and out of intensive care units under paucity of intensive care unit beds
    Elisheva Simchen
    Department of Health Services Research, Ministry of Health, Jerusalem, Israel
    Crit Care Med 32:1654-61. 2004
    ....
  39. ncbi Myocardial ischemia, cardiac troponin, and long-term survival of high-cardiac risk critically ill intensive care unit patients
    Giora Landesberg
    Department of Anesthesiology and Critical Care Medicine, Hadassah Medical Center, Jerusalem, Israel
    Crit Care Med 33:1281-7. 2005
    ..0, 3.2, and 2.99, respectively; p < .001). CONCLUSIONS: Silent ischemia is strongly associated with troponin elevation in high-cardiac-risk intensive care unit patients, and troponin elevation predicts both early and late mortality...
  40. ncbi Withdrawing and withholding life-sustaining therapies are not the same
    Phillip D Levin
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Hospital, Jerusalem, Israel
    Crit Care 9:230-2. 2005
    ..Appreciation of these differences allows the provision of accurate information, and facilitates decision making that is compassionate, caring and adherent to the needs of the patient and their family...
  41. ncbi Contamination of portable radiograph equipment with resistant bacteria in the ICU
    Phillip D Levin
    Departments of Anesthesiology, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Chest 136:426-32. 2009
    ....
  42. ncbi Intensive care outflow limitation--frequency, etiology, and impact
    Phillip D Levin
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Hospital, Jerusalem, Israel
    J Crit Care 18:206-11. 2003
    ..CONCLUSION: ICU outflow limitation occurs in up to 1 in 6 discharges. It can be due to medical deterioration, level of care issues or administrative problems, and may lead to inefficient use of ICU resources...
  43. ncbi The use of steroids in the treatment of severe sepsis and septic shock
    Baruch M Batzofin
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, PO Box 12000, Jerusalem 9112, Israel
    Best Pract Res Clin Endocrinol Metab 25:735-43. 2011
    ..We review the current literature and guidelines regarding low dose corticosteroid use in the management of sepsis and septic shock...
  44. ncbi Optimizing admissions to an intensive care unit
    Amir Shmueli
    Department of Health Management School of Public Health, The Hebrew University of Jerusalem, P O Box 12272, Jerusalem 91120, Israel
    Health Care Manag Sci 6:131-6. 2003
    ..9%. Implementing the more complex optimal bed specific hurdle policy would save an additional 1.4 statistical lives annually beyond what can be achieved with FCFS-H, a marginal improvement of only 1.2%...
  45. ncbi Use of the nonwire central line hub to reduce blood culture contamination
    Phillip D Levin
    Departments of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Chest 143:640-5. 2013
    ..The current study explored whether use of the CVC nonwire hub as a source of blood cultures decreased contamination while maintaining detection of true pathogens...
  46. ncbi Cultural differences at the end of life
    Phillip D Levin
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 31:S354-7. 2003
  47. ncbi Chapter 1. Introduction. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Intensive Care Med 36:S4-10. 2010
    ..In December 2007, the European Society of Intensive Care Medicine established a Task Force to develop standard operating procedures (SOPs) for operating intensive care units (ICU) during an influenza epidemic or mass disaster...
  48. ncbi Multiple casualty terror events: the anesthesiologist's perspective
    Micha Y Shamir
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, POB 12000, Jerusalem 91120, Israel
    Anesth Analg 98:1746-52, table of contents. 2004
    ..Operational issues faced by a department of anesthesiology during the initial 8 h after terrorist actions were examined. Multiple, and often parallel, efforts were required of the department...
  49. ncbi Corticosteroid therapy for patients in septic shock: Some progress in a difficult decision
    Charles L Sprung
    From the Department of Anesthesiology and Critical Care Medicine CLS, SG, YGW and the Center for Clinical Quality and Safety MB, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 39:571-4. 2011
    ..The present study was to investigate whether endotoxin tolerance occurs in the adrenal gland, leading to hyporesponsiveness of adrenal gland during sepsis...
  50. ncbi An internet web site as a data collection platform for multicenter research
    Alexander Avidan
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center Jerusalem, Ein Karem, PO Box 12000, Jerusalem 91120, Israel
    Anesth Analg 100:506-11. 2005
    ..Overall satisfaction of the investigators was high. After security issues, interactivity and user-friendly design are the main cornerstones for the success of such a system...
  51. ncbi The dying patient: new Israeli legislation
    Avraham Steinberg
    Medical Ethics Unit, Shaare Zedek Medical Center, Jerusalem, Israel
    Intensive Care Med 32:1234-7. 2006
  52. ncbi The International Sepsis Forum's controversies in sepsis: corticosteroids should be used to treat septic shock
    Sergey Goodman
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, The Hebrew University of Jerusalem, Israel
    Crit Care 6:381-3. 2002
    ..Based on the high proportion of patients who have relative adrenal insufficiency, the benefits of low doses of steroids and the minimal risks, steroids should be used to treat septic shock...
  53. ncbi Use of the pulmonary artery catheter is not associated with worse outcome in the ICU
    Yasser Sakr
    Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Route de Lennik 808, B-1070 Brussels, Belgium
    Chest 128:2722-31. 2005
    ..Survival to 60 days was similar between the two matched groups (log rank = 0.02; p = 0.894). CONCLUSIONS: This observational study suggests that PAC use is not associated with increased mortality in this heterogeneous population...
  54. ncbi Using corticosteroids in intensive care
    Paul E Marik
    Arch Surg 141:946-7; author reply 947. 2006
  55. ncbi End-of-life variations around the world: can we improve our caring?
    Sigal Sviri
    Crit Care Med 34:1837-8. 2006
  56. ncbi Does dopamine administration in shock influence outcome? Results of the Sepsis Occurrence in Acutely Ill Patients (SOAP) Study
    Yasser Sakr
    Department of Intensive Care, Erasme Hospital, Free University of Brussels, Belgium
    Crit Care Med 34:589-97. 2006
    ..The optimal adrenergic support in shock is controversial. We investigated whether dopamine administration influences the outcome from shock...
  57. ncbi Family-physician interactions in the intensive care unit
    Elie Azoulay
    Medical ICU, Saint-Louis Teaching Hospital, and Paris 7 University Paris, France
    Crit Care Med 32:2323-8. 2004
    ....
  58. ncbi End-of-life care in the intensive care unit: the Irish Ethicus data
    Niamh Collins
    University College Hospital Galway, Ireland
    Crit Care Resusc 8:315-20. 2006
    ..To study the frequency, rationale and process for withholding (WH) and withdrawing (WD) life-sustaining therapies in intensive care patients in Ireland...
  59. ncbi Adrenal function in sepsis: the retrospective Corticus cohort study
    Diane Lipiner Friedman
    Service de Reanimation, Hôpital Raymond Poincaré APHP, Faculté de Médecine Paris Ile de France Ouest UVSQ, Garches, France
    Crit Care Med 35:1012-8. 2007
    ..To refine the value of baseline and adrenocorticotropin hormone (ACTH)-stimulated cortisol levels in relation to mortality from severe sepsis or septic shock...
  60. ncbi The world's major religions' points of view on end-of-life decisions in the intensive care unit
    Hans Henrik Bulow
    Department of Anaesthesiology and Intensive Care, Holbak Hospital, Smedelundsgade 60, 4300 Holbak, Denmark
    Intensive Care Med 34:423-30. 2008
    ..This review also discusses whether nutrition should be provided to patients in a permanent vegetative state, and the issues of brain death and organ donation...
  61. ncbi Corticosteroid insufficiency in acutely ill patients
    Djillali Annane
    N Engl J Med 348:2157-9. 2003
  62. ncbi Forgoing life-sustaining treatments: comparison of attitudes between Israeli and North American intensive care healthcare professionals
    Ethan Soudry
    Medical Education Unit, Technion Faculty of Medicine, Haifa, Israel
    Isr Med Assoc J 5:770-4. 2003
    ..S. They differ from their U.S. counterparts in that they confer less significance to the will of the patient, and do not consult as much with families of patients regarding DNR orders...
  63. ncbi Sepsis in European intensive care units: results of the SOAP study
    Jean-Louis Vincent
    Department of Intensive Care, Erasme Hospital, Free University of Brussels, Belgium
    Crit Care Med 34:344-53. 2006
    ..In addition to age, a positive fluid balance was among the strongest prognostic factors for death. Patients with intensive care unit acquired sepsis have a worse outcome despite similar severity scores on intensive care unit admission...
  64. ncbi Clinical equipoise remains for issues of adrenocorticotropic hormone administration, cortisol testing, and therapeutic use of hydrocortisone
    Djillali Annane
    Crit Care Med 31:2250-1; author reply 2252-3. 2003
  65. ncbi Use of corticosteroid therapy in patients with sepsis and septic shock: an evidence-based review
    Didier Keh
    , , Berlin, Germany
    Crit Care Med 32:S527-33. 2004
    ....
  66. ncbi Intensive care triage--the hardest rationing decision of them all
    Phillip D Levin
    Crit Care Med 34:1250-1. 2006
  67. ncbi Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine
    Paul E Marik
    Division of Pulmonary and Critical Care Medicine, Thomas Jefferson University, Philadelphia, PA, USA
    Crit Care Med 36:1937-49. 2008
    ..To develop consensus statements for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients...
  68. ncbi Another point of view: no swan song for the pulmonary artery catheter
    Phillip D Levin
    Department of Anesthesia and Critical Care Medicine Hadassah Hebrew University Medical Center Jerusalem, Israel
    Crit Care Med 33:1123-4. 2005
  69. ncbi Mechanical ventilation of patients hospitalized in medical wards vs the intensive care unit--an observational, comparative study
    Moshe Hersch
    Intensive Care Unit, Shaare Zedek Medical Center, Jerusalem 91031, Israel
    J Crit Care 22:13-7. 2007
    ..In some hospitals, patients are mechanically ventilated on the wards in addition to the intensive care unit (ICU) because of the shortage of ICU beds...
  70. ncbi The pulmonary artery catheter: in medio virtus
    Jean Louis Vincent
    Department of Intensive Care Medicine, Erasme Hospital, Universite Libre de Bruxelles, Belgium
    Crit Care Med 36:3093-6. 2008
    ..To clarify the role of the pulmonary artery catheter in the intensive care unit...