Charles L Sprung

Summary

Affiliation: The Hebrew University
Country: Israel

Publications

  1. doi request reprint The Eldicus prospective, observational study of triage decision making in European intensive care units: part I--European Intensive Care Admission Triage Scores
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 40:125-31. 2012
  2. doi request reprint Chapter 1. Introduction. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Intensive Care Med 36:S4-10. 2010
  3. doi request reprint Chapter 5. Essential equipment, pharmaceuticals and supplies. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Intensive Care Med 36:S38-44. 2010
  4. doi request reprint The Eldicus prospective, observational study of triage decision making in European intensive care units. Part II: intensive care benefit for the elderly
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 40:132-8. 2012
  5. doi request reprint Recommendations for intensive care unit and hospital preparations for an influenza epidemic or mass disaster: summary report of the European Society of Intensive Care Medicine's Task Force for intensive care unit triage during an influenza epidemic or mas
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Intensive Care Med 36:428-43. 2010
  6. ncbi request reprint Reasons, considerations, difficulties and documentation of end-of-life decisions in European intensive care units: the ETHICUS Study
    Charles L Sprung
    Hadassah Hebrew University Medical Center, General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, P O Box 12000, 91120 Jerusalem, Israel
    Intensive Care Med 34:271-7. 2008
  7. ncbi request reprint Relieving suffering or intentionally hastening death: where do you draw the line?
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 36:8-13. 2008
  8. doi request reprint Effect of infections on 30-day mortality among critically ill patients hospitalized in and out of the intensive care unit
    George Mnatzaganian
    Department of Health Services Research, Ministry of Health, Jerusalem, Israel
    Crit Care Med 36:1097-104. 2008
  9. ncbi request reprint The importance of religious affiliation and culture on end-of-life decisions in European intensive care units
    Charles L Sprung
    General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Medical Center, Hadassah Hebrew University, P O Box 12000, 91120, Jerusalem, Israel
    Intensive Care Med 33:1732-9. 2007
  10. ncbi request reprint Survival of critically ill patients hospitalized in and out of intensive care
    Elisheva Simchen
    Department of Health Services Research, Ministry of Health, Jerusalem, Israel
    Crit Care Med 35:449-57. 2007

Detail Information

Publications44

  1. doi request reprint The Eldicus prospective, observational study of triage decision making in European intensive care units: part I--European Intensive Care Admission Triage Scores
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 40:125-31. 2012
    ..The objective of this study was to develop an intensive care unit triage decision rule based on 28-day mortality rates of admitted and refused patients...
  2. doi request reprint Chapter 1. Introduction. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Intensive Care Med 36:S4-10. 2010
    ..In December 2007, the European Society of Intensive Care Medicine established a Task Force to develop standard operating procedures (SOPs) for operating intensive care units (ICU) during an influenza epidemic or mass disaster...
  3. doi request reprint Chapter 5. Essential equipment, pharmaceuticals and supplies. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Intensive Care Med 36:S38-44. 2010
    ..To provide recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza pandemic or mass disaster with a specific focus on essential equipment, pharmaceuticals and supplies...
  4. doi request reprint The Eldicus prospective, observational study of triage decision making in European intensive care units. Part II: intensive care benefit for the elderly
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 40:132-8. 2012
    ..Life and death triage decisions are made daily by intensive care unit physicians. Admission to an intensive care unit is denied when intensive care unit resources are constrained, especially for the elderly...
  5. doi request reprint Recommendations for intensive care unit and hospital preparations for an influenza epidemic or mass disaster: summary report of the European Society of Intensive Care Medicine's Task Force for intensive care unit triage during an influenza epidemic or mas
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Intensive Care Med 36:428-43. 2010
    ..To provide recommendations and standard operating procedures for intensive care units and hospital preparedness for an influenza pandemic...
  6. ncbi request reprint Reasons, considerations, difficulties and documentation of end-of-life decisions in European intensive care units: the ETHICUS Study
    Charles L Sprung
    Hadassah Hebrew University Medical Center, General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, P O Box 12000, 91120 Jerusalem, Israel
    Intensive Care Med 34:271-7. 2008
    ..To evaluate physicians' reasoning, considerations and possible difficulties in end-of-life decision-making for patients in European intensive care units (ICUs)...
  7. ncbi request reprint Relieving suffering or intentionally hastening death: where do you draw the line?
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 36:8-13. 2008
    ..End-of-life practices vary worldwide. The objective was to demonstrate that there is no clear-cut distinction between treatments administered to relieve pain and suffering and those intended to shorten the dying process...
  8. doi request reprint Effect of infections on 30-day mortality among critically ill patients hospitalized in and out of the intensive care unit
    George Mnatzaganian
    Department of Health Services Research, Ministry of Health, Jerusalem, Israel
    Crit Care Med 36:1097-104. 2008
    ..This analysis is part of a multicenter study conducted in Israel to evaluate survival of critically ill patients treated in and out of intensive care units (ICUs)...
  9. ncbi request reprint The importance of religious affiliation and culture on end-of-life decisions in European intensive care units
    Charles L Sprung
    General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Medical Center, Hadassah Hebrew University, P O Box 12000, 91120, Jerusalem, Israel
    Intensive Care Med 33:1732-9. 2007
    ..To determine the influence of religious affiliation and culture on end-of-life decisions in European intensive care units (ICUs)...
  10. ncbi request reprint Survival of critically ill patients hospitalized in and out of intensive care
    Elisheva Simchen
    Department of Health Services Research, Ministry of Health, Jerusalem, Israel
    Crit Care Med 35:449-57. 2007
    ..The survival of such patients is largely unknown. The present study's objective was to screen entire hospitals for newly deteriorated patients and compare their survival in and out of the intensive care unit...
  11. ncbi request reprint Attitudes of European physicians, nurses, patients, and families regarding end-of-life decisions: the ETHICATT study
    Charles L Sprung
    General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, PO Box 12000, 91120, Jerusalem, Israel
    Intensive Care Med 33:104-10. 2007
    ..To evaluate attitudes of Europeans regarding end-of-life decisions...
  12. ncbi request reprint Nurse involvement in end-of-life decision making: the ETHICUS Study
    Julie Benbenishty
    Hadassah Medical Organization, Jerusalem, Israel
    Intensive Care Med 32:129-32. 2006
    ..The purpose was to investigate physicians' perceptions of the role of European intensive care nurses in end-of-life decision making...
  13. ncbi request reprint Conventional terrorist bomb incidents and the intensive care unit
    Micha Y Shamir
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University School of Medicine, Hadassah Medical Organization, Jerusalem, Israel
    Curr Opin Crit Care 11:580-4. 2005
    ....
  14. doi request reprint End-of-life treatment and bacterial antibiotic resistance: a potential association
    Phillip D Levin
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Chest 138:588-94. 2010
    ..Great variability exists in the occurrence of antibiotic-resistant bacteria in ICUs around the world. The contribution of specific ICU care variables to these geographic variations is unknown...
  15. doi request reprint Antimicrobial use in the ICU: indications and accuracy--an observational trial
    Phillip D Levin
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Hosp Med 7:672-8. 2012
    ..Antimicrobials may therefore be overused, contributing to development of antimicrobial-resistant bacteria...
  16. doi request reprint Triage of intensive care patients: identifying agreement and controversy
    Charles L Sprung
    General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, P O Box 12000, Jerusalem, 91120, Israel
    Intensive Care Med 39:1916-24. 2013
    ..Intensive care unit (ICU) resources are limited in many hospitals. Patients with little likelihood of surviving are often admitted to ICUs. Others who might benefit from ICU are not admitted...
  17. pmc Diastolic dysfunction and mortality in severe sepsis and septic shock
    Giora Landesberg
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel
    Eur Heart J 33:895-903. 2012
    ..In contrast, diastolic dysfunction is often ignored and its role in determining early mortality from sepsis has not been adequately investigated...
  18. ncbi request reprint Cortisol changes among patients with septic shock and the relationship to ICU and hospital stay
    Sergei Goodman
    Department of Anesthesiology and Critical Care Medicine, Hadassah University Hospital, Hadassah Medical School, Hebrew University, P O B 12000, 91120 Jerusalem, Israel
    Intensive Care Med 31:1362-9. 2005
    ..To evaluate adrenal function in patients with severe sepsis or septic shock...
  19. pmc Blood cultures at central line insertion in the intensive care unit: comparison with peripheral venipuncture
    Sheldon Stohl
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Centre, POB 12000, Jerusalem 91120, Israel
    J Clin Microbiol 49:2398-403. 2011
    ..This may be related to the increased manipulations required for CVC insertion...
  20. pmc Clinical review: the Israeli experience: conventional terrorism and critical care
    Gabriella Aschkenasy-Steuer
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University School of Medicine, Hadassah Medical Organization, Jerusalem, Israel
    Crit Care 9:490-9. 2005
    ..This review emphasizes the importance of a multidisciplinary team approach in caring for these patients...
  21. ncbi request reprint Assessing the in-hospital survival benefits of intensive care
    Amir Shmueli
    Department of Health Management, The Hebrew University, Jerusalem, Israel
    Int J Technol Assess Health Care 21:66-72. 2005
    ..The objective of this study is to assess the differential survival benefits of a general intensive care unit (ICU) by acute diagnoses and by Acute Physiological and Chronic Health Evaluation (APACHE II) scores...
  22. ncbi request reprint Caring for a major government official: challenges and lessons learned
    Yoram G Weiss
    Departments of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 35:1769-72. 2007
    ..Analysis of the medical, organizational, and administrative issues surrounding the care of a dignitary in an intensive care unit...
  23. doi request reprint Use of the nonwire central line hub to reduce blood culture contamination
    Phillip D Levin
    Departments of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Chest 143:640-5. 2013
    ..The current study explored whether use of the CVC nonwire hub as a source of blood cultures decreased contamination while maintaining detection of true pathogens...
  24. pmc Improved ICU design reduces acquisition of antibiotic-resistant bacteria: a quasi-experimental observational study
    Phillip D Levin
    Department of Anesthesia and Critical Care, Hadassah Hebrew University Medical Center, POB 12000, Jerusalem 91120, Israel
    Crit Care 15:R211. 2011
    ..The role of ICU design and particularly single-patient rooms in decreasing bacterial transmission between ICU patients has been debated. A recent change in our ICU allowed further investigation...
  25. pmc Withdrawing and withholding life-sustaining therapies are not the same
    Phillip D Levin
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Hospital, Jerusalem, Israel
    Crit Care 9:230-2. 2005
    ..Appreciation of these differences allows the provision of accurate information, and facilitates decision making that is compassionate, caring and adherent to the needs of the patient and their family...
  26. doi request reprint Characteristics of patients receiving vasopressors
    Julie Benbenishty
    Department of Anesthesia and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Heart Lung 40:247-52. 2011
    ..Patients receiving intensive care frequently need pharmacologic support of their blood pressure because of shock. In some patients, shock is so severe that extremely high doses of vasopressors are needed to elevate their blood pressure...
  27. doi request reprint Steroid therapy of septic shock
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Clin 25:825-34, x. 2009
    ..It reviews and contrasts several low- and high-dose steroid studies, and makes recommendations for future practice...
  28. ncbi request reprint Myocardial ischemia, cardiac troponin, and long-term survival of high-cardiac risk critically ill intensive care unit patients
    Giora Landesberg
    Department of Anesthesiology and Critical Care Medicine, Hadassah Medical Center, Jerusalem, Israel
    Crit Care Med 33:1281-7. 2005
    ..To determine the incidence and association of myocardial ischemia with troponin elevation and survival in high-cardiac-risk intensive care patients...
  29. doi request reprint Hydrocortisone therapy for patients with septic shock
    Charles L Sprung
    Hadassah Hebrew University Medical Center, Jerusalem, Israel 91120
    N Engl J Med 358:111-24. 2008
    ....
  30. ncbi request reprint Survival of critically ill patients hospitalized in and out of intensive care units under paucity of intensive care unit beds
    Elisheva Simchen
    Department of Health Services Research, Ministry of Health, Jerusalem, Israel
    Crit Care Med 32:1654-61. 2004
    ..The object was to screen entire hospital patient populations for critically ill patients and compare their 30-day survival in and out of the intensive care unit...
  31. ncbi request reprint Intensive care physicians' attitudes concerning distribution of intensive care resources. A comparison of Israeli, North American and European cohorts
    Sharon Einav
    Department of Anesthesiology and Critical Care Medicine, Hadassah Medical Center, Hebrew University of Jerusalem, POB 12000, 91120 Jerusalem, Israel
    Intensive Care Med 30:1140-3. 2004
    ..To evaluate the attitudes of Israeli intensive care physicians regarding intensive care unit (ICU) triage issues...
  32. ncbi request reprint An evaluation of systemic inflammatory response syndrome signs in the Sepsis Occurrence In Acutely Ill Patients (SOAP) study
    Charles L Sprung
    Hadassah Hebrew University, Medical Center, Department of Anaesthesiology and Critical Care Medicine, P O Box 1200, 91120, Jerusalem, Israel
    Intensive Care Med 32:421-7. 2006
    ..To define the frequency and prognostic implications of SIRS criteria in critically ill patients hospitalized in European ICUs...
  33. ncbi request reprint The dying patient act, 2005: Israeli innovative legislation
    Avraham Steinberg
    Medical Ethics Unit and Department of Pediatrics, Shaare Zedek Medical Center, Jerusalem, Israel
    Isr Med Assoc J 9:550-2. 2007
    ....
  34. doi request reprint The use of steroids in the treatment of severe sepsis and septic shock
    Baruch M Batzofin
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, PO Box 12000, Jerusalem 9112, Israel
    Best Pract Res Clin Endocrinol Metab 25:735-43. 2011
    ..We review the current literature and guidelines regarding low dose corticosteroid use in the management of sepsis and septic shock...
  35. doi request reprint Steroid therapy of septic shock
    Charles L Sprung
    General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Nurs Clin North Am 23:171-80. 2011
    ..Finally, steroid therapy should not be guided by corticotropin test results...
  36. doi request reprint Contamination of portable radiograph equipment with resistant bacteria in the ICU
    Phillip D Levin
    Departments of Anesthesiology, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Chest 136:426-32. 2009
    ....
  37. ncbi request reprint End-of-life practices in European intensive care units: the Ethicus Study
    Charles L Sprung
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    JAMA 290:790-7. 2003
    ....
  38. ncbi request reprint An internet web site as a data collection platform for multicenter research
    Alexander Avidan
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center Jerusalem, Ein Karem, PO Box 12000, Jerusalem 91120, Israel
    Anesth Analg 100:506-11. 2005
    ..Overall satisfaction of the investigators was high. After security issues, interactivity and user-friendly design are the main cornerstones for the success of such a system...
  39. ncbi request reprint Evaluation of changes in forgoing life-sustaining treatment in Israeli ICU patients
    Daniel J Jakobson
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, The Hebrew University of Jerusalem, PO Box 12000, Jerusalem, Israel 91120, USA
    Chest 126:1969-73. 2004
    ..Over the last several years, there have been legal decisions and changes in medical directives concerning end-of-life decisions in Israel...
  40. ncbi request reprint Multiple casualty terror events: the anesthesiologist's perspective
    Micha Y Shamir
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, POB 12000, Jerusalem 91120, Israel
    Anesth Analg 98:1746-52, table of contents. 2004
    ..Therefore, anesthesiology departments are greatly impacted by such events and must plan for them to maximize the use of available personnel and to have the appropriate equipment and supplies available...
  41. ncbi request reprint The dying patient: new Israeli legislation
    Avraham Steinberg
    Medical Ethics Unit, Shaare Zedek Medical Center, Jerusalem, Israel
    Intensive Care Med 32:1234-7. 2006
  42. ncbi request reprint Intensive care outflow limitation--frequency, etiology, and impact
    Phillip D Levin
    Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Hospital, Jerusalem, Israel
    J Crit Care 18:206-11. 2003
    ..To assess the frequency, causes, and effect of unsuccessful discharge decisions from the ICU...
  43. ncbi request reprint Corticosteroid therapy for patients in septic shock: Some progress in a difficult decision
    Charles L Sprung
    From the Department of Anesthesiology and Critical Care Medicine CLS, SG, YGW and the Center for Clinical Quality and Safety MB, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Crit Care Med 39:571-4. 2011
    ..The present study was to investigate whether endotoxin tolerance occurs in the adrenal gland, leading to hyporesponsiveness of adrenal gland during sepsis...
  44. ncbi request reprint Peter Sjokvist
    Charles L Sprung
    General Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Hadassah Hebrew University Medical Center, PO Box 12000, 91120 Jerusalem, Israel
    Intensive Care Med 30:1250-1. 2004