Eitan Shaulian

Summary

Affiliation: The Hebrew University
Country: Israel

Publications

  1. ncbi request reprint AP-1 as a regulator of cell life and death
    Eitan Shaulian
    Department of Experimental Medicine and Cancer Research, School of Medicine, The Hebrew University, Jerusalem, 91120, Israel
    Nat Cell Biol 4:E131-6. 2002
  2. doi request reprint Jun proteins are starvation-regulated inhibitors of autophagy
    Orli Yogev
    Department of Biochemistry and Molecular Biology, Institute for Medical Research Israel Canada, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Cancer Res 70:2318-27. 2010
  3. doi request reprint AP-1--The Jun proteins: Oncogenes or tumor suppressors in disguise?
    Eitan Shaulian
    Department of Biochemistry and Molecular Biology, The Institute for Medical Research Israel Canada, The Hebrew University Hadassah Medical School, Jerusalem, Israel
    Cell Signal 22:894-9. 2010
  4. doi request reprint DNA damage-dependent translocation of B23 and p19 ARF is regulated by the Jun N-terminal kinase pathway
    Orli Yogev
    Department of Experimental Medicine and Cancer Research, Hebrew University Medical School, Jerusalem, Israel
    Cancer Res 68:1398-406. 2008
  5. pmc Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response
    Ohad Yogev
    Department of Microbiology and Molecular Genetics, IMRIC, Faculty of Medicine, Hebrew University, Jerusalem, Israel
    PLoS Biol 8:e1000328. 2010
  6. doi request reprint Transcriptional repression of c-Jun's E3 ubiquitin ligases contributes to c-Jun induction by UV
    Shira Anzi
    Department of Experimental Medicine and Cancer Research, Hebrew University Medical School, Ein Kerem, Jerusalem, Israel
    Cell Signal 20:862-71. 2008
  7. pmc Metalloprotease type III effectors that specifically cleave JNK and NF-κB
    Kobi Baruch
    Department of Microbiology and Molecular Genetics, IMRIC, The Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, Israel
    EMBO J 30:221-31. 2011
  8. doi request reprint Jun proteins inhibit autophagy and induce cell death
    Orli Yogev
    Department of Biochemistry and Molecular Biology, IMRIC, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Autophagy 6:566-7. 2010
  9. ncbi request reprint Induction of transcriptionally active Jun proteins regulates drug-induced senescence
    Orli Yogev
    Department of Experimental Medicine and Cancer Research, Hebrew University Medical School, Hadassah Ein Kerem, Jerusalem 91120, Israel
    J Biol Chem 281:34475-83. 2006

Collaborators

  • Yinon Ben-Neriah
  • Michael Karin
  • Orli Yogev
  • Shira Anzi
  • Ohad Yogev
  • Kobi Baruch
  • Kazushi Inoue
  • Gal Yerushalmi
  • Raz Zarivach
  • Chen Guttman
  • Ilan Rosenshine
  • Chen Nadler
  • Lihi Gur-Arie
  • Simi Koby
  • Thomas D Fox
  • Michal Goldberg
  • Rachel Goldberg
  • Ophry Pines
  • Esti Singer
  • Shlomo Finkin
  • Keren Saadon

Detail Information

Publications9

  1. ncbi request reprint AP-1 as a regulator of cell life and death
    Eitan Shaulian
    Department of Experimental Medicine and Cancer Research, School of Medicine, The Hebrew University, Jerusalem, 91120, Israel
    Nat Cell Biol 4:E131-6. 2002
    ..Mostly, c-Jun is a positive regulator of cell proliferation, whereas JunB has the converse effect. The intricate relationships between the different Jun proteins, their activities and the mechanisms that mediate them will be discussed...
  2. doi request reprint Jun proteins are starvation-regulated inhibitors of autophagy
    Orli Yogev
    Department of Biochemistry and Molecular Biology, Institute for Medical Research Israel Canada, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Cancer Res 70:2318-27. 2010
    ..Most importantly, inhibition of autophagy in starved HeLa cells by JunB enhances apoptotic cell death. We suggest that JunB and c-Jun are regulators of autophagy whose expression responds to autophagy-inducing signals...
  3. doi request reprint AP-1--The Jun proteins: Oncogenes or tumor suppressors in disguise?
    Eitan Shaulian
    Department of Biochemistry and Molecular Biology, The Institute for Medical Research Israel Canada, The Hebrew University Hadassah Medical School, Jerusalem, Israel
    Cell Signal 22:894-9. 2010
    ..These recent findings suggest that the role of each Jun protein in neoplasia as well as in cellular survival should be examined in a context-dependent manner...
  4. doi request reprint DNA damage-dependent translocation of B23 and p19 ARF is regulated by the Jun N-terminal kinase pathway
    Orli Yogev
    Department of Experimental Medicine and Cancer Research, Hebrew University Medical School, Jerusalem, Israel
    Cancer Res 68:1398-406. 2008
    ..In senescent cells, JNK activity and c-Jun levels are reduced concomitantly with ARF nucleolar accumulation, and UV radiation does not cause the translocation of ARF...
  5. pmc Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response
    Ohad Yogev
    Department of Microbiology and Molecular Genetics, IMRIC, Faculty of Medicine, Hebrew University, Jerusalem, Israel
    PLoS Biol 8:e1000328. 2010
    ..This study shows an exciting crosstalk between primary metabolism and the DNA damage response, thereby providing a scenario for metabolic control of tumor propagation...
  6. doi request reprint Transcriptional repression of c-Jun's E3 ubiquitin ligases contributes to c-Jun induction by UV
    Shira Anzi
    Department of Experimental Medicine and Cancer Research, Hebrew University Medical School, Ein Kerem, Jerusalem, Israel
    Cell Signal 20:862-71. 2008
    ....
  7. pmc Metalloprotease type III effectors that specifically cleave JNK and NF-κB
    Kobi Baruch
    Department of Microbiology and Molecular Genetics, IMRIC, The Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, Israel
    EMBO J 30:221-31. 2011
    ..This is a remarkable example of a pathogen using multiple effectors to manipulate systematically the host inflammatory response signalling network...
  8. doi request reprint Jun proteins inhibit autophagy and induce cell death
    Orli Yogev
    Department of Biochemistry and Molecular Biology, IMRIC, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Autophagy 6:566-7. 2010
    ..Deregulation of JunB expression when autophagy is specifically required, tilts the fate of starved cells to apoptosis...
  9. ncbi request reprint Induction of transcriptionally active Jun proteins regulates drug-induced senescence
    Orli Yogev
    Department of Experimental Medicine and Cancer Research, Hebrew University Medical School, Hadassah Ein Kerem, Jerusalem 91120, Israel
    J Biol Chem 281:34475-83. 2006
    ..The effect of HU treatment, which regulates the intricate web of AP-1 transcription, depends on the balance between c-Jun and JunB activities...