Boris Rubinsky

Summary

Affiliation: The Hebrew University
Country: Israel

Publications

  1. ncbi Irreversible electroporation: a new ablation modality--clinical implications
    Boris Rubinsky
    Center for Biomedical Engineering in the Service of Humanity and Society, School of Engineering and Computer Science, Hebrew University of Jerusalem, Givaat Ram Campus, Jerusalem, 91906 Israel
    Technol Cancer Res Treat 6:37-48. 2007
  2. pmc Cellular phone enabled non-invasive tissue classifier
    Shlomi Laufer
    Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 4:e5178. 2009
  3. doi Tissue characterization with an electrical spectroscopy SVM classifier
    Shlomi Laufer
    Research Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem 91904, Israel
    IEEE Trans Biomed Eng 56:525-8. 2009
  4. doi Multiple biopsy probe sampling enabled minimally invasive electrical impedance tomography
    Mohanad Shini
    Center for Bioengineering, Service of Humanity and Society, School of Engineering and Computer Science, Hebrew University of Jerusalem, Givat Ram Campus, Jerusalem, Israel
    Physiol Meas 29:109-26. 2008
  5. ncbi Irreversible electroporation in medicine
    Boris Rubinsky
    Department of Bioengineering, Graduate Group in Biophysics, University of California at Berkeley, Berkeley, CA 94720, USA
    Technol Cancer Res Treat 6:255-60. 2007
  6. pmc Irreversible electroporation of human primary uveal melanoma in enucleated eyes
    Yossi Mandel
    Hansen Experimental Physics Laboratory, Stanford University, Stanford, California, United States of America Center for Bioengineering in the Service of Humanity and Society, School of Engineering and Computer Science, Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 8:e71789. 2013
  7. ncbi Irreversible electroporation: implications for prostate ablation
    Gary Onik
    Center for Bioengineering in the Service of Humanity and Society, School of Engineering and Computer Science, Hebrew University of Jerusalem, Givaat Ram Campus, Jerusalem, Israel 91904
    Technol Cancer Res Treat 6:295-300. 2007
  8. pmc Irreversible electroporation for microbial control of drugs in solution
    Alex Golberg
    Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem, Israel
    AAPS PharmSciTech 10:881-6. 2009
  9. doi Magnetic resonance imaging characteristics of nonthermal irreversible electroporation in vegetable tissue
    Mohammad Hjouj
    Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem, Israel
    J Membr Biol 236:137-46. 2010
  10. doi Electrical impedance characterization of normal and cancerous human hepatic tissue
    Shlomi Laufer
    Research Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem, Israel
    Physiol Meas 31:995-1009. 2010

Collaborators

Detail Information

Publications29

  1. ncbi Irreversible electroporation: a new ablation modality--clinical implications
    Boris Rubinsky
    Center for Biomedical Engineering in the Service of Humanity and Society, School of Engineering and Computer Science, Hebrew University of Jerusalem, Givaat Ram Campus, Jerusalem, 91906 Israel
    Technol Cancer Res Treat 6:37-48. 2007
    ..Last, we show that mathematical predictions with the Laplace equation can be used in treatment planning. The IRE tissue ablation technique, as characterized in this report, may become an important new tool in the surgeon armamentarium...
  2. pmc Cellular phone enabled non-invasive tissue classifier
    Shlomi Laufer
    Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 4:e5178. 2009
    ..This mode of operation has applications in remote non-invasive tissue diagnostics in situ in the body, in combination with medical imaging, as well as in remote diagnostics of biopsy samples in vitro...
  3. doi Tissue characterization with an electrical spectroscopy SVM classifier
    Shlomi Laufer
    Research Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem 91904, Israel
    IEEE Trans Biomed Eng 56:525-8. 2009
    ..The results demonstrate the feasibility of the concept and illustrate the tissue characterization ability of this classifier...
  4. doi Multiple biopsy probe sampling enabled minimally invasive electrical impedance tomography
    Mohanad Shini
    Center for Bioengineering, Service of Humanity and Society, School of Engineering and Computer Science, Hebrew University of Jerusalem, Givat Ram Campus, Jerusalem, Israel
    Physiol Meas 29:109-26. 2008
    ..We show that these images can detect tumors that would be missed with multiple biopsy samplings only, and that the technique may facilitate the detection of tumors with fewer biopsies, thereby reducing the cost of cancer detection...
  5. ncbi Irreversible electroporation in medicine
    Boris Rubinsky
    Department of Bioengineering, Graduate Group in Biophysics, University of California at Berkeley, Berkeley, CA 94720, USA
    Technol Cancer Res Treat 6:255-60. 2007
    ..A brief historical perspective of irreversible electroporation is presented and recent studies in the field are discussed...
  6. pmc Irreversible electroporation of human primary uveal melanoma in enucleated eyes
    Yossi Mandel
    Hansen Experimental Physics Laboratory, Stanford University, Stanford, California, United States of America Center for Bioengineering in the Service of Humanity and Society, School of Engineering and Computer Science, Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 8:e71789. 2013
    ..The effect was more pronounced near the pulsing electrodes and was dependent on time from treatment to fixation. Future studies should further evaluate the potential of IRE as an alternative method of uveal melanoma treatment. ..
  7. ncbi Irreversible electroporation: implications for prostate ablation
    Gary Onik
    Center for Bioengineering in the Service of Humanity and Society, School of Engineering and Computer Science, Hebrew University of Jerusalem, Givaat Ram Campus, Jerusalem, Israel 91904
    Technol Cancer Res Treat 6:295-300. 2007
    ..IRE lesions have characteristics that are distinctly different than thermal lesions. The differences could be very advantageous in a clinical setting, improving the results and acceptance of prostate ablation...
  8. pmc Irreversible electroporation for microbial control of drugs in solution
    Alex Golberg
    Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem, Israel
    AAPS PharmSciTech 10:881-6. 2009
    ..The principles established in this study can be applied to any drug in solution and optimized individually according to the solution's composition...
  9. doi Magnetic resonance imaging characteristics of nonthermal irreversible electroporation in vegetable tissue
    Mohammad Hjouj
    Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem, Israel
    J Membr Biol 236:137-46. 2010
    ..We find that NTIRE produces changes in vegetative tissue that can be imaged by certain MRI sequences. This could make MRI an effective tool to study the fundamentals of NTIRE in nonanimal tissue...
  10. doi Electrical impedance characterization of normal and cancerous human hepatic tissue
    Shlomi Laufer
    Research Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem, Israel
    Physiol Meas 31:995-1009. 2010
    ....
  11. pmc Distributed network, wireless and cloud computing enabled 3-D ultrasound; a new medical technology paradigm
    Arie Meir
    Center for Bioengineering in the Service of Humanity and Society, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 4:e7974. 2009
    ..This could enable relatively untrained medical workers in developing nations to administer imaging and a more accurate diagnosis, effectively saving the lives of people...
  12. ncbi In vivo results of a new focal tissue ablation technique: irreversible electroporation
    Jon F Edd
    Department of Mechanical Engineering, University of California, Berkeley, CA 94720, USA
    IEEE Trans Biomed Eng 53:1409-15. 2006
    ..Mathematical analysis indicates that this damage was primarily nonthermal in nature and that sharp borders between affected and unaffected regions corresponded to electric fields of 300-500 V/cm...
  13. pmc Imaging cryosurgery with EIT: tracking the ice front and post-thaw tissue viability
    Jon F Edd
    Department of Mechanical Engineering, University of California, Berkeley, CA 94720, USA
    Physiol Meas 29:899-912. 2008
    ....
  14. ncbi Irreversible electroporation attenuates neointimal formation after angioplasty
    Elad Maor
    Biophysics Graduate Group, University of California, Berkeley, CA 94720, USA
    IEEE Trans Biomed Eng 55:2268-74. 2008
    ..Irreversible electroporation (IRE) is a nonthermal, nonpharmacological cell ablation method. IRE utilizes a sequence of electrical pulses that produce permanent damage to tissue within a few seconds...
  15. ncbi Distributed network imaging and electrical impedance tomography of minimally invasive surgery
    David M Otten
    Dept of Mechanical Engineering, University of California at Berkeley, CA 94720, USA
    Technol Cancer Res Treat 3:125-34. 2004
    ..We find that the acquired raw data packets are less than 5KB per image and the images, using compression, do not exceed 50KB per image...
  16. ncbi Theoretical analysis of the thermal effects during in vivo tissue electroporation
    Rafael V Davalos
    Department of Mechanical Engineering, 6178 Etcheverry Hall University of California at Berkeley, Berkeley, CA 94720 1740, USA
    Bioelectrochemistry 61:99-107. 2003
    ..However, for needle electrodes, the geometry, i.e. spacing and diameter, and pulse frequency are critical when determining the thermal distribution in the tissue...
  17. ncbi Electrical and thermal characterization of nanochannels between a cell and a silicon based micro-pore
    Ruben E Diaz-Rivera
    Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA 94720, USA
    Biomed Microdevices 8:25-34. 2006
    ....
  18. ncbi Electrical impedance tomography for imaging tissue electroporation
    Rafael V Davalos
    Biomedical Engineering Laboratory, Department of Mechanical Engineering, 6178 Etcheverry Hall, University of California at Berkeley, Berkeley, CA 94720 1740, USA
    IEEE Trans Biomed Eng 51:761-7. 2004
    ..Combining EIT with electroporation could become an important biotechnological and medical technique to introduce therapeutic molecules into cells in tissue at predetermined areas of the body...
  19. pmc Tumor ablation with irreversible electroporation
    Bassim Al-Sakere
    CNRS UMR 8121, Institut Gustave Roussy, Villejuif, France
    PLoS ONE 2:e1135. 2007
    ..These conditions induced complete regression in 12 out of 13 treated tumors, (92%), in the absence of tissue heating. Irreversible electroporation is thus a new effective modality for non-thermal tumor ablation...
  20. ncbi Impedance analyzer for in vivo electroporation studies
    Antoni Ivorra
    University of California at Berkely, CA 94720, USA
    Conf Proc IEEE Eng Med Biol Soc 1:5056-9. 2006
    ..Here we describe the apparatus and illustrate its use with an experiment on reversible electroporation in a rat liver...
  21. ncbi In vivo electrical impedance measurements during and after electroporation of rat liver
    Antoni Ivorra
    Department of Bioengineering and Department of Mechanical Engineering, University of California at Berkeley, Berkeley, CA 94720, USA
    Bioelectrochemistry 70:287-95. 2007
    ..This suggests the superposition of different phenomena which together affect the electrical properties...
  22. ncbi Cancer cells ablation with irreversible electroporation
    Liron Miller
    Neufeld Cardiac Research Institute, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Israel
    Technol Cancer Res Treat 4:699-705. 2005
    ..We also find that the use of multiple pulses appears to be more effective for cancer cell ablation than the application of the same energy in one single pulse...
  23. ncbi Electric field modulation in tissue electroporation with electrolytic and non-electrolytic additives
    Antoni Ivorra
    Department of Bioengineering, University of California at Berkeley, California, Berkeley, CA 94720, USA
    Bioelectrochemistry 70:551-60. 2007
    ..The feasibility of the concept is demonstrated experimentally in vivo with a rat liver subjected to irreversible electroporation...
  24. ncbi A novel nonthermal energy source for surgical epicardial atrial ablation: irreversible electroporation
    Jacob Lavee
    Department of Cardiothoracic Surgery, Sheba Medical Center, Tel Hashomer, Israel
    Heart Surg Forum 10:E162-7. 2007
    ..IRE utilizes a sequence of electrical pulses that produce permanent nonthermal damage to tissue in a few seconds with sharp borders between affected and unaffected regions...
  25. ncbi Temperature dependence of tissue impedivity in electrical impedance tomography of cryosurgery
    Jon F Edd
    Department of Mechanical Engineering, University of California, Berkeley, CA 94720, USA
    IEEE Trans Biomed Eng 52:695-701. 2005
    ..This error decreases with increasing blood perfusion and with higher measurement frequencies...
  26. ncbi Electrical impedance tomography of cell viability in tissue with application to cryosurgery
    Rafael Davalos
    Biomedical Engineering Laboratory Department of Mechanical Engineering, 6178 Etcheverry Hall University of California at Berkeley, Berkeley, CA 94720 1740, USA
    J Biomech Eng 126:305-9. 2004
    ..Two-dimensional EIT simulations of liver cryosurgery, which employ the experimental data, demonstrate the feasibility of this application...
  27. ncbi The effect of irreversible electroporation on blood vessels
    Elad Maor
    Department of Biomedical Engineering, Department of Mechanical Engineering, Graduate Program in Biophysics, University of California at Berkeley, Berkeley, CA 94720, USA
    Technol Cancer Res Treat 6:307-12. 2007
    ....
  28. ncbi Methods of optimization of electrical impedance tomography for imaging tissue electroporation
    Yair Granot
    Biophysics Group, UC Berkeley, Berkeley, CA 94720, USA
    Physiol Meas 28:1135-47. 2007
    ..This mathematical study employs recently collected in vivo data of rat liver electroporation to obtain a model which represents, as closely as possible, the reality of electroporation procedures...
  29. ncbi A feasibility study for electrical impedance tomography as a means to monitor tissue electroporation for molecular medicine
    Rafael V Davalos
    Department of Mechanical Engineering, University of California at Berkeley, 94720, USA
    IEEE Trans Biomed Eng 49:400-3. 2002
    ....