Israel Nelken

Summary

Affiliation: The Hebrew University
Country: Israel

Publications

  1. ncbi request reprint Responses of neurons in the inferior colliculus to binaural disparities: insights from the use of Fisher information and mutual information
    Noam Gordon
    Department of Neurobiology, Silberman Institute of Life Sciences, Hebrew University, Givat Ram, Jerusalem 91904, Israel
    J Neurosci Methods 169:391-404. 2008
  2. ncbi request reprint Encoding stimulus information by spike numbers and mean response time in primary auditory cortex
    Israel Nelken
    Department of Neurobiology and The Interdisciplinary Center for Neural Computation, Hebrew University, Jerusalem, Israel
    J Comput Neurosci 19:199-221. 2005
  3. ncbi request reprint Processing of complex stimuli and natural scenes in the auditory cortex
    Israel Nelken
    Department of Neurobiology, The Silberman Institute of Life Sciences, and the Interdisciplinary Center for Neural Computations, Givat Ram 91904, Jerusalem, Israel
    Curr Opin Neurobiol 14:474-80. 2004
  4. ncbi request reprint Large-scale organization of ferret auditory cortex revealed using continuous acquisition of intrinsic optical signals
    Israel Nelken
    Dept of Neurobiology, The Alexander Silberman Institute for Life Sciences, Hebrew University, Jerusalem 91904, Israel
    J Neurophysiol 92:2574-88. 2004
  5. ncbi request reprint Primary auditory cortex of cats: feature detection or something else?
    Israel Nelken
    Department of Physiology, Hebrew University Hadassah Medical School, and the Interdisciplinary Center for Neural Computation, The Hebrew University, 12272, 91120, Jerusalem, Israel
    Biol Cybern 89:397-406. 2003
  6. ncbi request reprint Responses of auditory cortex to complex stimuli: functional organization revealed using intrinsic optical signals
    Israel Nelken
    Department of Neurobiology, Interdisciplinary Center for Neural Computation, The Hebrew University, Jerusalem, Israel
    J Neurophysiol 99:1928-41. 2008
  7. doi request reprint Elevated correlations in neuronal ensembles of mouse auditory cortex following parturition
    Gideon Rothschild
    Department of Neurobiology, Institute of Life Sciences and Edmond and Lily Safra Center for Brain Sciences, Hebrew University of Jerusalem, Jerusalem 91904, Israel
    J Neurosci 33:12851-61. 2013
  8. doi request reprint Functional gradients of auditory sensitivity along the anterior ectosylvian sulcus of the cat
    Liora Las
    Department of Neurobiology, The Alexander Silberman Institute of Life Sciences, Hebrew University, Jerusalem 91904, Israel
    J Neurosci 28:3657-67. 2008
  9. ncbi request reprint Responses of neurons in primary auditory cortex (A1) to pure tones in the halothane-anesthetized cat
    Dina Moshitch
    Department of Neurobiology, The Alexander Silberman Institute of Life Sciences, Faculty of Sciences, Hadassah Medical School, The Hebrew University, Edmund Safra Campus, Givat Ram, Jerusalem 91904, Israel
    J Neurophysiol 95:3756-69. 2006
  10. ncbi request reprint Representation of tone in fluctuating maskers in the ascending auditory system
    Liora Las
    Department of Neurobiology, Edmund Safra Campus, Givat Ram, and Interdisciplinary Center for Neural Computation, Hebrew University, Jerusalem 91904, Israel
    J Neurosci 25:1503-13. 2005

Detail Information

Publications35

  1. ncbi request reprint Responses of neurons in the inferior colliculus to binaural disparities: insights from the use of Fisher information and mutual information
    Noam Gordon
    Department of Neurobiology, Silberman Institute of Life Sciences, Hebrew University, Givat Ram, Jerusalem 91904, Israel
    J Neurosci Methods 169:391-404. 2008
    ....
  2. ncbi request reprint Encoding stimulus information by spike numbers and mean response time in primary auditory cortex
    Israel Nelken
    Department of Neurobiology and The Interdisciplinary Center for Neural Computation, Hebrew University, Jerusalem, Israel
    J Comput Neurosci 19:199-221. 2005
    ....
  3. ncbi request reprint Processing of complex stimuli and natural scenes in the auditory cortex
    Israel Nelken
    Department of Neurobiology, The Silberman Institute of Life Sciences, and the Interdisciplinary Center for Neural Computations, Givat Ram 91904, Jerusalem, Israel
    Curr Opin Neurobiol 14:474-80. 2004
    ..Evidence with converging implications suggests that the neuronal activity in primary auditory cortex represents sounds in terms of auditory objects rather than in terms of invariant acoustic features...
  4. ncbi request reprint Large-scale organization of ferret auditory cortex revealed using continuous acquisition of intrinsic optical signals
    Israel Nelken
    Dept of Neurobiology, The Alexander Silberman Institute for Life Sciences, Hebrew University, Jerusalem 91904, Israel
    J Neurophysiol 92:2574-88. 2004
    ..Although responsive to pure tones, these areas exhibit less tonotopic order than the primary fields...
  5. ncbi request reprint Primary auditory cortex of cats: feature detection or something else?
    Israel Nelken
    Department of Physiology, Hebrew University Hadassah Medical School, and the Interdisciplinary Center for Neural Computation, The Hebrew University, 12272, 91120, Jerusalem, Israel
    Biol Cybern 89:397-406. 2003
    ....
  6. ncbi request reprint Responses of auditory cortex to complex stimuli: functional organization revealed using intrinsic optical signals
    Israel Nelken
    Department of Neurobiology, Interdisciplinary Center for Neural Computation, The Hebrew University, Jerusalem, Israel
    J Neurophysiol 99:1928-41. 2008
    ....
  7. doi request reprint Elevated correlations in neuronal ensembles of mouse auditory cortex following parturition
    Gideon Rothschild
    Department of Neurobiology, Institute of Life Sciences and Edmond and Lily Safra Center for Brain Sciences, Hebrew University of Jerusalem, Jerusalem 91904, Israel
    J Neurosci 33:12851-61. 2013
    ..Our results demonstrate changes in the correlation structure of neuronal activity as a result of a natural life event. ..
  8. doi request reprint Functional gradients of auditory sensitivity along the anterior ectosylvian sulcus of the cat
    Liora Las
    Department of Neurobiology, The Alexander Silberman Institute of Life Sciences, Hebrew University, Jerusalem 91904, Israel
    J Neurosci 28:3657-67. 2008
    ..We conclude that in cats, pAES contains a secondary auditory cortical field which is specialized for spatial processing, in particular for the representation of frontal space...
  9. ncbi request reprint Responses of neurons in primary auditory cortex (A1) to pure tones in the halothane-anesthetized cat
    Dina Moshitch
    Department of Neurobiology, The Alexander Silberman Institute of Life Sciences, Faculty of Sciences, Hadassah Medical School, The Hebrew University, Edmund Safra Campus, Givat Ram, Jerusalem 91904, Israel
    J Neurophysiol 95:3756-69. 2006
    ..Furthermore, A1 units maintain sensory information in their activity not only throughout sound presentation but also for hundreds of milliseconds after stimulus offset, thus possibly playing a role in sensory memory...
  10. ncbi request reprint Representation of tone in fluctuating maskers in the ascending auditory system
    Liora Las
    Department of Neurobiology, Edmund Safra Campus, Givat Ram, and Interdisciplinary Center for Neural Computation, Hebrew University, Jerusalem 91904, Israel
    J Neurosci 25:1503-13. 2005
    ....
  11. ncbi request reprint Processing of low-probability sounds by cortical neurons
    Nachum Ulanovsky
    Department of Physiology, Hebrew University, Hadassah Medical School, Box 12272, Jerusalem 91120, Israel
    Nat Neurosci 6:391-8. 2003
    ..Our results thus indicate that A1 neurons, in addition to processing the acoustic features of sounds, may also be involved in sensory memory and novelty detection...
  12. ncbi request reprint Multiple time scales of adaptation in auditory cortex neurons
    Nachum Ulanovsky
    Department of Neurobiology, The Alexander Silberman Institute of Life Sciences, Hebrew University, Jerusalem 91904, Israel
    J Neurosci 24:10440-53. 2004
    ..This SSA might play a role in stream segregation and in binding of auditory objects over many time scales, a property that is crucial for processing of natural auditory scenes in cats and of speech and music in humans...
  13. doi request reprint Intracellular correlates of stimulus-specific adaptation
    Itai Hershenhoren
    Department of Neurobiology, Institute of Life Sciences, The Interdisciplinary Center for Neural Computation, and The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    J Neurosci 34:3303-19. 2014
    ..We conclude that local processing significantly contributes to the generation of cortical SSA. ..
  14. doi request reprint Functional organization and population dynamics in the mouse primary auditory cortex
    Gideon Rothschild
    Department of Neurobiology, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel
    Nat Neurosci 13:353-60. 2010
    ..Our findings may account for apparent discrepancies between ordered large-scale organization and local heterogeneity...
  15. doi request reprint Stimulus-specific adaptation beyond pure tones
    Israel Nelken
    Department of Neurobiology, Hebrew University, Jerusalem, Israel
    Adv Exp Med Biol 787:411-8. 2013
    ..Thus, differential adaptation to common and rare sounds is present also with sounds whose complexity mirrors that of natural environments...
  16. ncbi request reprint Reduction of information redundancy in the ascending auditory pathway
    Gal Chechik
    Interdisciplinary Center for Neural Computation, Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Neuron 51:359-68. 2006
    ..IC redundancy was largely related to frequency selectivity. Redundancy reduction may be a generic organization principle of neural systems, allowing for easier readout of the identity of complex stimuli in A1 relative to IC...
  17. ncbi request reprint Information theory in auditory research
    Israel Nelken
    Department of Neurobiology and The Interdisciplinary Center for Neural Computation, Silberman Institute of Life Sciences, Safra Campus, Givat Ram, Hebrew University, Jerusalem, Israel
    Hear Res 229:94-105. 2007
    ..Second, it discusses those aspects of the MI that makes its calculation difficult. The goal of this paper is to clarify when and how information theory can be used informatively and reliably in auditory neuroscience...
  18. doi request reprint Stimulus uncertainty and perceptual learning: similar principles govern auditory and visual learning
    Mor Nahum
    Interdisciplinary Center for Neural Computation, Hebrew University, Jerusalem, Israel
    Vision Res 50:391-401. 2010
    ..In both modalities, the effects of variability on learning can be explained by the introduction of obstructions to a search mechanism going down along the sensory processing hierarchy, as suggested by the Reverse Hierarchy Theory...
  19. ncbi request reprint Encoding by response duration in the basal ganglia
    Naama Parush
    Interdisciplinary Center for Neural Computation, Department of Physiology, Hadassah Medical School, The Hebrew University, Jerusalem, Israel
    J Neurophysiol 100:3244-52. 2008
    ..Thus response duration is not simply correlated with the discharge rate and can provide additional information to the target structures of the BG...
  20. doi request reprint Processing of complex sounds in the auditory system
    Israel Nelken
    Department of Neurobiology, Silberman Institute of Life Sciences, and the Interdisciplinary Center for Neural Computation ICNC, Hebrew University, Safra Campus, Jerusalem 91904, Israel
    Curr Opin Neurobiol 18:413-7. 2008
    ..A1 is clearly much more than a 'whiteboard' of acoustic information-neurons in A1 have complex response properties, showing sensitivity to both low-level and high-level features of sounds...
  21. ncbi request reprint Responses of neurons in cat primary auditory cortex to bird chirps: effects of temporal and spectral context
    Omer Bar-Yosef
    Department of Physiology, Hebrew University Hadassah Medical School, Hebrew University, Jerusalem 91120, Israel
    J Neurosci 22:8619-32. 2002
    ..These results illustrate the sensitivity of neurons in AI to small perturbations of their acoustic input. In particular, they pose a challenge to models based on linear summation of energy within a spectrotemporal receptive field...
  22. doi request reprint Sensitivity to complex statistical regularities in rat auditory cortex
    Amit Yaron
    Department of Neurobiology, Institute of Life Sciences, Jerusalem 91904, Israel
    Neuron 76:603-15. 2012
    ..We conclude that neurons in auditory cortex are sensitive to the detailed structure of sound sequences over timescales of minutes...
  23. pmc Reverse hierarchies and sensory learning
    Merav Ahissar
    The Hebrew University, Jerusalem 91905, Israel
    Philos Trans R Soc Lond B Biol Sci 364:285-99. 2009
    ....
  24. doi request reprint Transient induced gamma-band response in EEG as a manifestation of miniature saccades
    Shlomit Yuval-Greenberg
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem 91905, Israel
    Neuron 58:429-41. 2008
    ..Thus, whereas neuronal gamma-band oscillations were shown conclusively with other methods, the broadband transient iGBR recorded by scalp EEG reflects properties of miniature saccade dynamics rather than neuronal oscillations...
  25. pmc Stimulus-specific adaptation and deviance detection in the rat auditory cortex
    Nevo Taaseh
    Department of Neurobiology, Silberman Institute of Life Sciences, Hebrew University, Jerusalem, Israel
    PLoS ONE 6:e23369. 2011
    ..Thus, the response to a deviant is at least partially due to the change it represents relative to the regularity set by the standard tone, indicating the presence of true deviance detection in rat auditory cortex...
  26. doi request reprint Inhibitory plasticity in auditory cortex
    Israel Nelken
    Department of Neurobiology, The Silberman Institute of Life Sciences, The Hebrew University, Edmond Safra Campus Givat Ram, Jerusalem 91904, Israel
    Neuron 62:605-7. 2009
    ..demonstrate the important role that increased inhibition may play in shaping cortical responses to behaviorally relevant stimuli...
  27. ncbi request reprint Using Tweedie distributions for fitting spike count data
    Dina Moshitch
    Department of Neurobiology, Silberman Institute of Life Sciences, Hebrew University, Jerusalem, Israel Electronic address
    J Neurosci Methods 225:13-28. 2014
    ..In more than half of the cases, the variance of neuronal responses showed a supralinear dependence on the mean spike count...
  28. doi request reprint Single neuron and population coding of natural sounds in auditory cortex
    Adi Mizrahi
    Department of Neurobiology, Institute for Life Sciences and The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Edmond J Safra Campus, Givat Ram, Jerusalem 91904, Israel Electronic address
    Curr Opin Neurobiol 24:103-10. 2014
    ..Finally, we suggest a synthesis of how single neurons and subnetworks may be involved in coding natural sounds. ..
  29. pmc Auditory processing deficits in reading disabled adults
    Sygal Amitay
    Interdisciplinary Center for Neural Computation, Hebrew University, Jerusalem 91904, Israel
    J Assoc Res Otolaryngol 3:302-20. 2002
    ....
  30. pmc Neurons and objects: the case of auditory cortex
    Israel Nelken
    Department of Neurobiology, The Silberman Institute of Life Sciences, Edmund Safra Campus, Hebrew University Jerusalem, Israel
    Front Neurosci 2:107-13. 2008
    ....
  31. pmc Low-level information and high-level perception: the case of speech in noise
    Mor Nahum
    Interdisciplinary Center for Neural Computation, Hebrew University, Jerusalem, Israel
    PLoS Biol 6:e126. 2008
    ..Only auditory RHT could account for the full pattern of the results, suggesting that similar defaults and tradeoffs underlie the relations between hierarchical processing and perception in the visual and auditory modalities...
  32. ncbi request reprint Neural model for physiological responses to frequency and amplitude transitions uncovers topographical order in the auditory cortex
    Alon Fishbach
    Department of Physiology, Northwestern University, Chicago, Illinois 60611, USA
    J Neurophysiol 90:3663-78. 2003
    ..These results suggest a possible ordered organization of a simple rotatable spectrotemporal receptive field in the mammalian AI...
  33. ncbi request reprint Cortical processing of complex sound: a way forward?
    Timothy D Griffiths
    Department of Psychology, University College London, London WC1H 0AP, UK
    Trends Neurosci 27:181-5. 2004
    ..There is a crucial need for better understanding of the anatomy of the auditory cortex in different species and for comparative studies that will underpin both approaches...
  34. ncbi request reprint Physiological and anatomical evidence for multisensory interactions in auditory cortex
    Jennifer K Bizley
    Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford OX1 3PT, UK
    Cereb Cortex 17:2172-89. 2007
    ..These data indicate that multisensory convergence and integration are features common to all auditory cortical areas but are especially prevalent in higher areas...
  35. ncbi request reprint Functional organization of ferret auditory cortex
    Jennifer K Bizley
    University Laboratory of Physiology, Parks Road, Oxford OX1 3PT, UK
    Cereb Cortex 15:1637-53. 2005
    ..The presence of both tonotopic and non-tonotopic auditory cortical fields indicates that the organization of ferret auditory cortex is comparable to that seen in other mammals...