S Harrus

Summary

Affiliation: The Hebrew University
Country: Israel

Publications

  1. ncbi request reprint Serum protein alterations in canine ehrlichiosis
    S Harrus
    Small Animal, Internal Medicine Department, School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
    Vet Parasitol 66:241-9. 1996
  2. doi request reprint Molecular detection of Rickettsia massiliae, Rickettsia sibirica mongolitimonae and Rickettsia conorii israelensis in ticks from Israel
    S Harrus
    Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel
    Clin Microbiol Infect 17:176-80. 2011
  3. doi request reprint Diagnosis of canine monocytotropic ehrlichiosis (Ehrlichia canis): an overview
    Shimon Harrus
    Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
    Vet J 187:292-6. 2011
  4. ncbi request reprint Isolation and genetic characterization of a Bartonella strain closely related to Bartonella tribocorum and Bartonella elizabethae in Israeli commensal rats
    Shimon Harrus
    Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
    Am J Trop Med Hyg 81:55-8. 2009
  5. ncbi request reprint Drivers for the emergence and re-emergence of vector-borne protozoal and bacterial diseases
    S Harrus
    School of Veterinary Medicine, The Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Int J Parasitol 35:1309-18. 2005
  6. pmc Comparison of simultaneous splenic sample PCR with blood sample PCR for diagnosis and treatment of experimental Ehrlichia canis infection
    Shimon Harrus
    School of Veterinary Medicine, Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Antimicrob Agents Chemother 48:4488-90. 2004
  7. doi request reprint Molecular detection of Ehrlichia canis, Anaplasma bovis, Anaplasma platys, Candidatus Midichloria mitochondrii and Babesia canis vogeli in ticks from Israel
    S Harrus
    Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel
    Clin Microbiol Infect 17:459-63. 2011
  8. ncbi request reprint Down-regulation of MHC class II receptors of DH82 cells, following infection with Ehrlichia canis
    Shimon Harrus
    School of Veterinary Medicine, The Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Vet Immunol Immunopathol 96:239-43. 2003
  9. ncbi request reprint Comparison of three enzyme-linked immunosorbant assays with the indirect immunofluorescent antibody test for the diagnosis of canine infection with Ehrlichia canis
    Shimon Harrus
    The Koret School of Veterinary Medicine, Hebrew University of Jerusalem, P O Box 12, 76100, Rehovot, Israel
    Vet Microbiol 86:361-8. 2002
  10. pmc Therapeutic effect of doxycycline in experimental subclinical canine monocytic ehrlichiosis: evaluation of a 6-week course
    S Harrus
    Department of Clinical Sciences, Veterinary Teaching Hospital, Hebrew University of Jerusalem, Rehovot, Israel
    J Clin Microbiol 36:2140-2. 1998

Detail Information

Publications39

  1. ncbi request reprint Serum protein alterations in canine ehrlichiosis
    S Harrus
    Small Animal, Internal Medicine Department, School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
    Vet Parasitol 66:241-9. 1996
    ..canis infected dogs is more compromised, and therefore secondary infections should be expected more frequently in these dogs...
  2. doi request reprint Molecular detection of Rickettsia massiliae, Rickettsia sibirica mongolitimonae and Rickettsia conorii israelensis in ticks from Israel
    S Harrus
    Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel
    Clin Microbiol Infect 17:176-80. 2011
    ..This study reports the first detection of R. massiliae and R. sibirica mongolitimonae in ticks from Israel. This is the first report describing the presence of these human pathogens in the Middle East...
  3. doi request reprint Diagnosis of canine monocytotropic ehrlichiosis (Ehrlichia canis): an overview
    Shimon Harrus
    Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
    Vet J 187:292-6. 2011
    ..canis infection requires molecular techniques. This article reviews the current literature covering the diagnosis of infection caused by E. canis...
  4. ncbi request reprint Isolation and genetic characterization of a Bartonella strain closely related to Bartonella tribocorum and Bartonella elizabethae in Israeli commensal rats
    Shimon Harrus
    Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
    Am J Trop Med Hyg 81:55-8. 2009
    ..rattus). The detection of a Bartonella genotype closely related to B. elizabethae in the biggest metropolitan center in Israel warrants further study of its zoonotic potential and pathogenic characteristics...
  5. ncbi request reprint Drivers for the emergence and re-emergence of vector-borne protozoal and bacterial diseases
    S Harrus
    School of Veterinary Medicine, The Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Int J Parasitol 35:1309-18. 2005
    ..A coordinated global approach for the prevention of vector-borne diseases should be implemented by international organizations and governmental agencies in collaboration with research institutions...
  6. pmc Comparison of simultaneous splenic sample PCR with blood sample PCR for diagnosis and treatment of experimental Ehrlichia canis infection
    Shimon Harrus
    School of Veterinary Medicine, Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Antimicrob Agents Chemother 48:4488-90. 2004
    ..Blood PCR was as valuable as splenic aspirate PCR for early diagnosis of acute CME. Splenic aspirate PCR was, however, superior to blood PCR for the evaluation of ehrlichial elimination...
  7. doi request reprint Molecular detection of Ehrlichia canis, Anaplasma bovis, Anaplasma platys, Candidatus Midichloria mitochondrii and Babesia canis vogeli in ticks from Israel
    S Harrus
    Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel
    Clin Microbiol Infect 17:459-63. 2011
    ..bovis and Candidatus Midichloria mitochondrii in Israel. To the best of the author's knowledge, this is the first report describing the detection of DNA of the latter two pathogens in R. sanguineus, and of A. bovis in R. turanicus...
  8. ncbi request reprint Down-regulation of MHC class II receptors of DH82 cells, following infection with Ehrlichia canis
    Shimon Harrus
    School of Veterinary Medicine, The Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Vet Immunol Immunopathol 96:239-43. 2003
    ..canis. The present results indicate that infection of DH82 macrophages with E. canis down-regulates their MHC class II receptors. These results suggest a possible mechanism by which E. canis evades the immune system...
  9. ncbi request reprint Comparison of three enzyme-linked immunosorbant assays with the indirect immunofluorescent antibody test for the diagnosis of canine infection with Ehrlichia canis
    Shimon Harrus
    The Koret School of Veterinary Medicine, Hebrew University of Jerusalem, P O Box 12, 76100, Rehovot, Israel
    Vet Microbiol 86:361-8. 2002
    ..Repeating the serological tests 1-2 weeks after the first antibody assay may overcome the sensitivity problem with titers of < or =1:320...
  10. pmc Therapeutic effect of doxycycline in experimental subclinical canine monocytic ehrlichiosis: evaluation of a 6-week course
    S Harrus
    Department of Clinical Sciences, Veterinary Teaching Hospital, Hebrew University of Jerusalem, Rehovot, Israel
    J Clin Microbiol 36:2140-2. 1998
    ..canis antibodies persisted after elimination of the parasite. Our findings suggest that an increase in the platelet count may be an important indicator for dogs that recover from subclinical ehrlichiosis...
  11. pmc Amplification of ehrlichial DNA from dogs 34 months after infection with Ehrlichia canis
    S Harrus
    Department of Clinical Sciences, School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
    J Clin Microbiol 36:73-6. 1998
    ..It was concluded that PCR of DNA extracted from splenic aspirates is a reliable method for determining the carrier state of CME...
  12. ncbi request reprint Acute blindness associated with monoclonal gammopathy induced by Ehrlichia canis infection
    S Harrus
    Department of Clinical Sciences, Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
    Vet Parasitol 78:155-60. 1998
    ..Blood hyperviscosity, elevation in oncotic pressure, vasculitis, thrombocytopenia and platelet dysfunction are all proposed to be important factors in the pathogenesis of acute blindness in canine monocytic ehrlichiosis...
  13. ncbi request reprint Investigation of splenic functions in canine monocytic ehrlichiosis
    S Harrus
    Department of Clinical Sciences, School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
    Vet Immunol Immunopathol 62:15-27. 1998
    ..Splenic inflammatory mediators and/or other splenic substances, are proposed to play a key role in the pathogenesis of the disease. Our results further substantiate the involvement of immune mechanisms in the pathogenesis of CME...
  14. ncbi request reprint Presence of immune-complexes, and absence of antinuclear antibodies, in sera of dogs naturally and experimentally infected with Ehrlichia canis
    S Harrus
    Department of Clinical Sciences, School of Veterinary Medicine, Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Vet Microbiol 83:343-9. 2001
    ..The results of this study suggest that ANA do not play a role in the pathogenesis of CME. It is however suggested that some manifestations in canine ehrlichiosis are immune-complex mediated...
  15. ncbi request reprint Dynamics of IgG1 and IgG2 subclass response in dogs naturally and experimentally infected with Ehrlichia canis
    S Harrus
    Department of Clinical Sciences, School of Veterinary Medicine, Hebrew University of Jerusalem, PO Box 12, 76100, Rehovot, Israel
    Vet Parasitol 99:63-71. 2001
    ..canis IgG was developed and was shown to be sensitive and specific for E. canis-IgG, and in a significant correlation with the indirect immunofluorescence antibody test...
  16. doi request reprint Prognostic indicators for canine monocytic ehrlichiosis
    A Shipov
    School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel
    Vet Parasitol 153:131-8. 2008
    ..75 mmol/L, each provided 100% prediction for survival. These prognostic indicators can be easily obtained at presentation, are inexpensive, and may be useful aids when treatment and prognosis are being considered...
  17. ncbi request reprint Hepatozoon species infection in domestic cats: a retrospective study
    G Baneth
    School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
    Vet Parasitol 79:123-33. 1998
    ..is a rare finding in cats from Israel. The over-representation of cats with a retroviral disease among the cats with hepatozoonosis indicates a possible association between immunosupression and the development of Hepatozoon infection...
  18. ncbi request reprint Fatal Vipera xanthina palestinae envenomation in 16 dogs
    I Aroch
    School of Veterinary Medicine, The Hebrew University of Jerusalem, PO Box 12, 76100 Rehovot, Israel
    Vet Hum Toxicol 46:268-72. 2004
    ..Necropsy performed on 3/16 dogs found soft tissue swelling and local bleeding at the envenomation sites as well as bleeding in several distal body organs and tissues...
  19. ncbi request reprint Seroprevalence of Anaplasma phagocytophilum among healthy dogs and horses in Israel
    O Levi
    Koret School of Veterinary Medicine, Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
    J Vet Med B Infect Dis Vet Public Health 53:78-80. 2006
    ..canis should also be considered. In spite of the high prevalence of ticks on horses in Israel during the summer months, no evidence for exposure to A. phagocytophilum was apparent...
  20. ncbi request reprint Spirocerca lupi in dogs: prophylactic effect of doramectin
    E Lavy
    Department of Clinical Sciences, School of Veterinary Medicine, Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Res Vet Sci 75:217-22. 2003
    ..This study shows that although doramectin did not entirely prevent canine spirocercosis it reduced the clinical signs associated with infection and delayed and reduced egg output...
  21. ncbi request reprint Vipera palaestinae envenomation in 327 dogs: a retrospective cohort study and analysis of risk factors for mortality
    G Segev
    School of Veterinary Medicine, The Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Toxicon 43:691-9. 2004
    ..Specific antivenom therapy (10 ml/dog) was not associated with a higher survival rate, thus its use, dose and timing of administration should be further investigated...
  22. ncbi request reprint Canine spirocercosis: clinical, diagnostic, pathologic, and epidemiologic characteristics
    Michal Mazaki-Tovi
    School of Veterinary Medicine, Hebrew University of Jerusalem, P O Box 12, 76100, Rehovot, Israel
    Vet Parasitol 107:235-50. 2002
    ..The case-fatality rate decreased toward the end of the study period when improved therapy with avermectins became available...
  23. ncbi request reprint Immune-mediated thrombocytopenia and putative haemolytic anaemia associated with a polyvalent botulism vaccination in a cow
    I Yeruham
    Koret School of Veterinary Medicine, Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
    Vet Rec 153:502-4. 2003
  24. ncbi request reprint Retrospective study of 46 cases of feline haemobartonellosis in Israel and their relationships with FeLV and FIV infections
    S Harrus
    School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel
    Vet Rec 151:82-5. 2002
    ..The cats infected with both Haemobartonella felis and FeLV had a significantly lower body temperature, were more anaemic and the mean cell volume of their erythrocytes was greater than in the cats with haemobartonellosis alone...
  25. doi request reprint Detection of Bartonella spp. in wild rodents in Israel using HRM real-time PCR
    Danny Morick
    Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Vet Microbiol 139:293-7. 2009
    ..Further investigation of the prevalence and zoonotic potential of the Bartonella species detected in the black rats and the Cairo spiny mouse is warranted...
  26. doi request reprint Longitudinal quantification of Ehrlichia canis in experimental infection with comparison to natural infection
    Gad Baneth
    School of Veterinary Medicine, Hebrew University, Rehovot 76100, Israel
    Vet Microbiol 136:321-5. 2009
    ..The value of real-time PCR was shown in NI dogs as well as in EI dogs with spleen and blood sampling more sensitive than non-invasive conjunctival PCR...
  27. ncbi request reprint Dirofilaria repens infection in a dog: diagnosis and treatment with melarsomine and doramectin
    Gad Baneth
    School of Veterinary Medicine, Hebrew University, P O Box 12, Rehovot 76100, Israel
    Vet Parasitol 105:173-8. 2002
    ..repens microfilaremia during a follow-up period of 90 days. Euthanasia and necropsy performed 3 months after the initiation of therapy due to a progressive neoplastic disease revealed no evidence of filariae...
  28. ncbi request reprint Spirocercosis-associated esophageal sarcomas in dogs. A retrospective study of 17 cases (1997-2003)
    Eyal Ranen
    School of Veterinary Medicine, The Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Vet Parasitol 119:209-21. 2004
    ..Proper surgical treatment could prolong the dogs' lifespan for months, and improve their quality of life...
  29. ncbi request reprint Evaluation of doramectin for the treatment of experimental canine spirocercosis
    Eran Lavy
    Department of Clinical Sciences, Koret School of Veterinary Medicine, Veterinary Teaching Hospital, The Hebrew University of Jerusalem, P O Box 12, 76100 Rehovot, Israel
    Vet Parasitol 109:65-73. 2002
    ..lupi granulomas could still be seen 544 days post-initiation of treatment with doramectin. Multiple subcutaneous injections of doramectin (400 microg/kg) were shown to be effective and safe in the treatment of canine spirocercosis...
  30. ncbi request reprint Spirocercosis-associated pyothorax in dogs
    Sigal Klainbart
    School of Veterinary Medicine, The Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    Vet J 173:209-14. 2007
    ..Conservative medical management of pyothorax with antihelmintic medication was shown to be effective in the treatment of S. lupi-associated pyothorax...
  31. ncbi request reprint Development of hypertrophic osteodystrophy and antibody response in a litter of vaccinated Weimaraner puppies
    S Harrus
    Department of Clinical Sciences, School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
    J Small Anim Pract 43:27-31. 2002
    ..The results obtained and the previously reported data suggest that a larger controlled study is needed to further elucidate the effect of different vaccination protocols on HOD and immunisation in Weimaraner puppies...
  32. doi request reprint Molecular detection of Bartonella henselae and Bartonella koehlerae from aortic valves of Boxer dogs with infective endocarditis
    Dan G Ohad
    Koret School of Veterinary Medicine, The Robert H Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Israel
    Vet Microbiol 141:182-5. 2010
    ..Moreover, this is the first report describing the detection of B. koehlerae from dogs...
  33. ncbi request reprint Polygenic detection of Rickettsia felis in cat fleas (Ctenocephalides felis) from Israel
    Omri Bauer
    School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel
    Am J Trop Med Hyg 74:444-8. 2006
    ..Although no clinical case has been reported in human beings in Israel to date, these findings suggest that this infection is prevalent in Israel...
  34. ncbi request reprint Rickettsia conorii in humans and dogs: a seroepidemiologic survey of two rural villages in Israel
    Shimon Harrus
    School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
    Am J Trop Med Hyg 77:133-5. 2007
    ..These results support a previous suggestion that canine serology could be a sensitive indicator for the presence and magnitude of human exposure to R. conorii...
  35. pmc Coinfection with multiple tick-borne and intestinal parasites in a 6-week-old dog
    Arnon Gal
    School of Veterinary Medicine, Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
    Can Vet J 48:619-22. 2007
    ....
  36. ncbi request reprint A serosurvey of Hepatozoon canis and Ehrlichia canis antibodies in wild red foxes (Vulpes vulpes) from Israel
    Zohar Fishman
    School of Veterinary Medicine, Hebrew University, P O Box 12, Rehovot 76100, Israel
    Vet Parasitol 119:21-6. 2004
    ..Canine ehrlichiosis and hepatozoonosis appear to be endemic in the wild red fox populations in Israel, and foxes may serve as a reservoir for infection of domestic dogs and other wild canine species...
  37. doi request reprint Identification of a Bartonella species in the harbor seal (Phoca vitulina) and in seal lice (Echinophtirius horridus)
    Danny Morick
    Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel
    Vector Borne Zoonotic Dis 9:751-3. 2009
    ..horridus. The 100% sequence similarity in the ITS of the Bartonella sp. identified with the zoonotic B. henselae warrants further investigation and characterization of this organism, which may be found to be of public health importance...
  38. pmc Characterization of the major antigenic protein 2 of Ehrlichia canis and Ehrlichia chaffeensis and its application for serodiagnosis of ehrlichiosis
    Tamece T Knowles
    Department of Pathobiology, College of Veterinary Medicine, University of Florida, Gainesville, Florida 32610, USA
    Clin Diagn Lab Immunol 10:520-4. 2003
    ..ELISA and Western blot analysis confirmed that the E. chaffeensis rMAP2 failed to serologically differentiate between E. canis and E. chaffeensis infections...
  39. ncbi request reprint Murine xenograft model of Spirocerca lupi-associated sarcoma
    Noa Stettner
    Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israeli
    Comp Med 55:510-4. 2005
    ..This resource will facilitate studies on the malignant transformation of the granulomas, establishment of efficient chemotherapy and radiotherapy regimens, and identification of diagnostic molecular markers...