Research Topics
Species | S GorinsteinSummaryAffiliation: The Hebrew University Country: Israel Publications
| Collaborators
|
Detail Information
Publications
Comparison of the contents of the main biochemical compounds and the antioxidant activity of some Spanish olive oils as determined by four different radical scavenging testsShela Gorinstein
Department of Medicinal Chemistry and Natural Products, The Hebrew University Hadassah Medical School, Jerusalem, Israel
J Nutr Biochem 14:154-9. 2003..Extra Virgin olive oil has high organoleptic properties and the highest antioxidant activity. The above-mentioned makes this oil a preferable choice for diseases preventing diets...
Plasma circulating fibrinogen stability and moderate beer consumptionShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, P O B 12065, Jerusalem 91120, Israel
J Nutr Biochem 14:710-6. 2003..Together, with the decrease in the PCF concentration it may lead to an elevation of the blood anticoagulant activity...
Influence of two cultivars of persimmon on atherosclerosis indices in rats fed cholesterol-containing diets: Investigation in vitro and in vivoShela Gorinstein
The Hebrew University, Hadassah Medical School, School of Pharmacy, The Institute for Drug Research, Jerusalem, Israel
Nutrition 27:838-46. 2011..To assess the influence of two persimmon cultivars on some atherosclerosis indices in rats fed cholesterol (Chol)-containing diets...
Raw and boiled garlic enhances plasma antioxidant activity and improves plasma lipid metabolism in cholesterol-fed ratsShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University, Hadassah Medical School, Jerusalem, Israel
Life Sci 78:655-63. 2006..Therefore it should be added at this time to foods. The selenium and copper content of raw garlic is not altered by boiling. The protein electrophoretic pattern of raw garlic is altered by boiling...
Changes in mussel Mytilus galloprovincialis protein profile as a reaction of water pollutionShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, Jerusalem, Israel
Environ Int 32:95-100. 2006..Estimated temperature and enthalpy of denaturation in the protein mussels well correlated with fluorescence and spectroscopic measurements and showed the changes influenced by water pollution...
Red Star Ruby (Sunrise) and blond qualities of Jaffa grapefruits and their influence on plasma lipid levels and plasma antioxidant activity in rats fed with cholesterol-containing and cholesterol-free dietsShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, Jerusalem 91120, Israel
Life Sci 77:2384-97. 2005..Jaffa grapefruits, especially their red Star Ruby quality, could be a valuable supplementation for diseases-preventing diets...
Changes in plasma lipid and antioxidant activity in rats as a result of naringin and red grapefruit supplementationShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, Jerusalem, Israel
J Agric Food Chem 53:3223-8. 2005..However, fresh red grapefruit is preferable than naringin: it more effectively influences plasma lipid levels and plasma antioxidant activity and, therefore, could be used as a valuable supplement for disease-preventing diets...
Comparison of the bioactive compounds and antioxidant potentials of fresh and cooked Polish, Ukrainian, and Israeli garlicShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, Jerusalem, Israel
J Agric Food Chem 53:2726-32. 2005....
Fresh israeli jaffa sweetie juice consumption improves lipid metabolism and increases antioxidant capacity in hypercholesterolemic patients suffering from coronary artery disease: studies in vitro and in humans and positive changes in albumin and fibrinogShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, P O Box 12065, Jerusalem 91120, Israel
J Agric Food Chem 52:5215-22. 2004..Addition of fresh Sweetie juice to generally accepted diets may be beneficial for hypercholesterolemic patients...
Fresh Israeli Jaffa blond (Shamouti) orange and Israeli Jaffa red Star Ruby (Sunrise) grapefruit juices affect plasma lipid metabolism and antioxidant capacity in rats fed added cholesterolShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, 91120 Jerusalem, Israel
J Agric Food Chem 52:4853-9. 2004....
Preventive effects of diets supplemented with sweetie fruits in hypercholesterolemic patients suffering from coronary artery diseaseShela Gorinstein
Department of Medicinal Chemistry and Natural Products, The Hebrew University of Jerusalem Hadassah Medical School, P O B 12065, Jerusalem 91120, Israel
Prev Med 38:841-7. 2004..Diets rich in vegetables and fruits prevent development of atherosclerosis...
Partial characterization of proteins from mussel Mytilus galloprovincialis as a biomarker of contaminationS Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, POB 12065, Jerusalem 91120, Israel
Arch Environ Contam Toxicol 49:504-10. 2005..Therefore, the above-mentioned indices could be used as additional biomarkers of sea water contamination...
Relationship between seawater pollution and qualitative changes in the extracted proteins from mussels Mytilus galloprovincialisShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, POB 12065, Jerusalem 91120, Israel
Sci Total Environ 364:251-9. 2006..galloprovincialis from polluted sites can be a reliable biomarker of the level of the seawater pollution...
Red grapefruit positively influences serum triglyceride level in patients suffering from coronary atherosclerosis: studies in vitro and in humansShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, P O Box 12065, Jerusalem 91120, Israel
J Agric Food Chem 54:1887-92. 2006..The addition of fresh red grapefruit to generally accepted diets could be beneficial for hyperlipidemic, especially hypertriglyceridemic, patients suffering from coronary atherosclerosis...
Some analytical assays for the determination of bioactivity of exotic fruitsShela Gorinstein
The Drug Research Institute of the School of Pharmacy, The Hebrew University, Hadassah Medical School, Jerusalem 91120, Israel
Phytochem Anal 21:355-62. 2010..As far as we know, no results of such comparative investigation of three tropical fruits (durian, mango and avocado) and the use of such tests for phytochemical control have been published...
The influence of raw and processed garlic and onions on plasma classical and non-classical atherosclerosis indices: investigations in vitro and in vivoShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University, Hadassah Medical School, Jerusalem, Israel
Phytother Res 24:706-14. 2010..Alkaline phosphatase levels correlated with classical atherosclerosis indices, and determination of alkaline phosphatase is suggested as an additional index in atherosclerosis testing...
The comparative characteristics of snake and kiwi fruitsShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University, Hadassah Medical School, Jerusalem 91120, Israel
Food Chem Toxicol 47:1884-91. 2009..Two fruits can be used as supplements to the normal diet. Consumption of a combination of both fruits could be recommended in order to receive the best results...
Comparison of the main bioactive compounds and antioxidant activities in garlic and white and red onions after treatment protocolsShela Gorinstein
Department of Medicinal Chemistry and Natural Products, The Hebrew University, Hadassah Medical School, P O Box 12065, Jerusalem 91120, Israel
J Agric Food Chem 56:4418-26. 2008..Quercetin quantity was the highest in red onion among the studied vegetables. The electrophoretic separation of nonreduced garlic and onion proteins after boiling demonstrated their degradation in the range from 50 to 112 kDa...
The atherosclerotic heart disease and protecting properties of garlic: contemporary dataShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, Jerusalem, Israel
Mol Nutr Food Res 51:1365-81. 2007..Many recently published reports show that garlic possesses plasma lipid-lowering and plasma anticoagulant and antioxidant properties and improves impaired endothelial function...
Aorta and liver changes in rats fed cholesterol-containing and raw vegetable-supplemented diets: experiments in vitro and in vivoShela Gorinstein
The Institute for Drug Research, School of Pharmacy, The Hebrew University, Hadassah Medical School, Jerusalem 91120, Israel
J Agric Food Chem 59:7441-51. 2011..In conclusion, all studied vegetables showed protective effects, but raw garlic supplemented with cholesterol-containing diets significantly prevented the aorta and liver damages of rats...
Bioactivity of beer and its influence on human metabolismShela Gorinstein
Department of Medicinal Chemistry and Natural Products, The Hebrew University Hadassah Medical School, Jerusalem, Israel
Int J Food Sci Nutr 58:94-107. 2007..The increase in the plasma albumin concentration and its antioxidant activity could be the markers of atherosclerosis status...
Dose-dependent influence of commercial garlic (Allium sativum) on rats fed cholesterol-containing dietShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, Jerusalem, Israel
J Agric Food Chem 54:4022-7. 2006..Therefore, commercial garlic (Elena, Zelazków, Poland) could be a valuable component of atherosclerosis-preventing diets only in optimal doses...
Alcohol beverages and biochemical changes in bloodShela Gorinstein
Department of Medicinal Chemistry adn Natural Products, The Hebrew University Hadassah Medical School, Jerusalem 91120, Israel
Addict Biol 8:445-54. 2003..This review summarizes the recent epidemiological, experimental and clinical investigations concerning mainly the plasma biochemical changes in lipid levels, anticoagulant and antioxidant activities...
Beer consumption and changes in stability of human serum proteinsS Gorinstein
Department of Medicinal Chemistry, School of Pharmacy, The Hebrew University Hadassah Medical School, P O Box 12065, Jerusalem 91120, Israel
J Agric Food Chem 49:1441-5. 2001..These qualitative changes were more profound in MPP than in Alb and Glo. Thus, Glo is more resistible to alcohol influence than Alb, which in turn is more resistible than MPP. No serum protein changes were detected in patients of CG...
Characterization of soluble amaranth and soybean proteins based on fluorescence, hydrophobicity, electrophoresis, amino Acid analysis, circular dichroism, and differential scanning calorimetry measurementsS Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, P O B 12065, Jerusalem 91120, Israel
J Agric Food Chem 49:5595-601. 2001..Predicted functional changes in model protein systems such as pseudocereals and legumes in response to processing conditions may be encountered in pharmaceutical and food industries. These plants can be a substitute for some cereals...
Structure characterization of human serum proteins in solution and dry stateS Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, POB 12065, Jerusalem 91120, Israel
J Pept Res 59:71-8. 2002..In summary, thermal denaturation parameters, fluorescence, So and the content of secondary structure have shown that HSG is more stable fraction than HSA...
Olive oils improve lipid metabolism and increase antioxidant potential in rats fed diets containing cholesterolShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University, Hadassah Medical School, Jerusalem, Israel
J Agric Food Chem 50:6102-8. 2002..It is more evident when these oils are added to the diets of rats fed cholesterol. These positive properties are attributed mostly to the phenolic compounds of the studied oils...
Structural changes in plasma circulating fibrinogen after moderate beer consumption as determined by electrophoresis and spectroscopyShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, P O Box 12065, Jerusalem 91120, Israel
J Agric Food Chem 51:822-7. 2003..Thus, in most of beer-consuming patients some qualitative structural changes in plasma circulating fibrinogen were detected...
Antioxidative properties of Jaffa sweeties and grapefruit and their influence on lipid metabolism and plasma antioxidative potential in ratsShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Hebrew University Hadassah Medical School, Jerusalem 91120, Israel
Biosci Biotechnol Biochem 67:907-10. 2003..These findings provide additional characterization of the nutritional value of citrus fruits and their influence on the lipid metabolism in rats...
Comparative contents of dietary fiber, total phenolics, and minerals in persimmons and applesS Gorinstein
Department of Medicinal Chemistry, School of Pharmacy, The Hebrew University Hadassah Medical School, P O Box 12065, Jerusalem 91120, Israel
J Agric Food Chem 49:952-7. 2001..The relatively high contents of dietary fibers, total and major phenolics, main minerals, and trace elements make persimmon preferable for an antiatherosclerotic diet...
Intrinsic tryptophan fluorescence of human serum proteins and related conformational changesS Gorinstein
Department of Medicinal Chemistry, School of Pharmacy, The Hebrew University, Hadassah Medical School, Jerusalem, Israel
J Protein Chem 19:637-42. 2000..Differences in the fluorescence behavior of the proteins are attributed to disruption of the structure of proteins by denaturants as well as by the change in their compactability as a result of ethanol consumption...
Moderate beer consumption and positive biochemical changes in patients with coronary atherosclerosisS Gorinstein
School of Pharmacy, Hebrew University of Jerusalem, Israel
J Intern Med 242:219-24. 1997..The aim of this study was to evaluate the influence of moderate beer consumption on lipid metabolism and antioxidant activity in patients (pts) with coronary artery disease (CAD)...
Antioxidants in the black mussel (Mytilus galloprovincialis) as an indicator of Black Sea coastal pollutionShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, P O Box 12065, Jerusalem 91120, Israel
Mar Pollut Bull 46:1317-25. 2003..The results presented in this report indicate that the antioxidant activities of mussel extracts could possibly be an additional index of pollution characterization...
Inter-relationship between electrophoretic characteristics of pseudocereal and cereal proteins and their microscopic structure for possible substitution based on nutritional evaluationShela Gorinstein
Department of Medicinal Chemistry and Natural Products, School of Pharmacy, The Hebrew University Hadassah Medical School, P O B 12065, Jerusalem 91120, Israel
Int J Food Sci Nutr 54:427-35. 2003..Pseudocereal amaranth can be used as a nutritive substitute of cereal maize in functional foods...
Computational analysis of the amino acid residue sequences of amaranth and some other proteinsS Gorinstein
Department of Pharmaceutical Chemistry, School of Pharmacy, Hebrew University of Jerusalem, Israel
Biosci Biotechnol Biochem 62:1845-51. 1998..Some relationship was shown among electrophoretic patterns of alcohol-soluble proteins and glutelins of A. caudatus...
Stability of some Cactaceae proteins based on fluorescence, circular dichroism, and differential scanning calorimetry measurementsS Gorinstein
Department of Pharmaceutical Chemistry, School of Pharmacy, The Hebrew University Hadassah Medical School, Jerusalem, Israel
J Protein Chem 18:239-47. 1999....
Evaluation of some cereals, plants and tubers through protein compositionS Gorinstein
Department of Medicinal Chemistry, School of Pharmacy, The Hebrew University Hadassah Medical School, Jerusalem, Israel
J Protein Chem 18:687-93. 1999..Electrophoretic patterns of the protein fractions are directly related to the genetic background of the protein and can be identified and used to certify the genetic makeup of wild, cultivated, or newly derived cereals and plants...
Effect of beer consumption on plasma magnesium: randomized comparison with mineral waterS Gorinstein
School of Pharmacy, Hebrew University of Jerusalem, Israel
J R Soc Med 91:631-3. 1998..89 (SD 0.01) to 0.98 (SD 0.02) mmol/L (P < 0.0025). This level of beer consumption did no obvious harm to liver function and its possibly beneficial effect on plasma magnesium deserves further investigation...
Durian (Durio zibethinus Murr.) cultivars as nutritional supplementation to rat's dietsHanna Leontowicz
Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw Agricultural University, Warsaw, Poland
Food Chem Toxicol 46:581-9. 2008..The durian fruit till now was not investigated extensively, therefore based on the results of this study durian cultivars can be used as a relatively new source of antioxidants...
Biochemical characteristics of the herb mixture Prolipid as a plant food supplement and medicinal remedyZenon Jastrzebski
Department of Pharmacology, National Medicines Institute, Chelmska str 30 34, 00 725, Warsaw, Poland
Plant Foods Hum Nutr 62:145-50. 2007..Prolipid is widely used in human treatment without known side effects on patients and is comparable to other medicinal plants, and as a strong antioxidant mixture could be used as a supplement to known atherosclerosis preventing diets...
In vitro studies of polyphenol compounds, total antioxidant capacity and other dietary indices in a mixture of plants (Prolipid)Zenon Jastrzebski
Department of Pharmacology, National Institute of Public Health, Warsaw, Poland
Int J Food Sci Nutr 58:531-41. 2007..Prolipid, a mixture of herbs, can therefore be used as a supplement for nutritional and healthy purposes...
The nutritional and metabolic indices in rats fed cholesterol-containing diets supplemented with durian at different stages of ripeningMaria Leontowicz
Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw Agricultural University, Warsaw, Poland
Biofactors 29:123-36. 2007..Therefore, the ripe durian supplemented diet could be beneficial for patient suffering from hypercholesterolemia and diabetes mellitus. <..
Antioxidant activity and cytotoxicity of methanol extracts from aerial parts of Korean salad plantsBuk Gu Heo
Naju Foundation of Natural Dyeing Cultural Institute, Naju, South Korea
Biofactors 30:79-89. 2007..Most of the studied salad plants have potent cytotoxicity activity. The results of this investigation suggest that the extracts of studied salad plants could be an addition to basic medicine for some diseases...
The bioactivity of processed garlic (Allium sativum L.) as shown in vitro and in vivo studies on ratsZenon Jastrzebski
Department of Pharmacology, Institute of Public Health, Warsaw, Poland
Food Chem Toxicol 45:1626-33. 2007..The diet supplemented with these samples and cholesterol improved lipid indices, decreased fibrinogen and increased antioxidant activity in plasma of rats. Therefore, for preservation of garlic bioactivity optimal regime has to be used...
Identification and differences of total proteins and their soluble fractions in some pseudocereals based on electrophoretic patternsJerzy Drzewiecki
Plant Breeding and Acclimatization Institute, Radzikow, Poland
J Agric Food Chem 51:7798-804. 2003..Some similarity was found between these plants in their soluble protein fractions and amino acid composition. These plants can be a substitution of each other as well as for cereals...
The influence of beer with different antioxidant potential on plasma lipids, plasma antioxidant capacity, and bile excretion of rats fed cholesterol-containing and cholesterol-free dietsBartosz Gasowski
Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw Agricultural University, Nowoursynowska 159, 02-787 Warsaw, Poland
J Nutr Biochem 15:527-33. 2004..It is suggested that to achieve the best results, beer with the highest antioxidant potential must be consumed...
Oat (Avena sativa L.) and amaranth (Amaranthus hypochondriacus) meals positively affect plasma lipid profile in rats fed cholesterol-containing dietsJan Czerwinski
Department of Physiology Science, Faculty of Veterinary Medicine, Warsaw Agricultural University, Nowoursynowska 159, 02 787 Warsaw, Poland
J Nutr Biochem 15:622-9. 2004..It is suggested that amaranth could be a valuable substitute for hypercholesterolemic patients allergic to cereals...
Apple and pear peel and pulp and their influence on plasma lipids and antioxidant potentials in rats fed cholesterol-containing dietsMaria Leontowicz
Department of Animal Physiology, Faculty of Veterinary Medicine, Warsaw Agricultural University, Nowoursynowska 166, 02-787 Warsaw, Poland
J Agric Food Chem 51:5780-5. 2003..05). Diets supplemented with fruit peels exercised a significantly higher positive influence on plasma lipid levels and on plasma antioxidant capacity of rats than diets with fruit pulps...
Effect of different olive oils on bile excretion in rats fed cholesterol-containing and cholesterol-free dietsRyszard Krzeminski
Department of Animal Physiology, Faculty of Veterinary Medicine, Warsaw Agricultural University, Nowoursynowska 166, 02-787 Warsaw, Poland
J Agric Food Chem 51:5774-9. 2003..The hypocholesterolemic effect of olive oils is genuine and is most likely mediated through increases in bile flow and biliary cholesterol and bile acids concentrations and subsequent increases in their fecal excretion...
Seasonal variability of phytoplankton at Varna Bay (Black Sea)Snejana Moncheva
Institute of Oceanology, Department of Biology and Ecology, Bulgarian Academy of Sciences, P.O. Box 152, Varna 9000, Bulgaria
Phytochem Anal 14:245-50. 2003..All of these changes could be accounted for by the adaptation of the organism to seasonal variations that modify the sea environment at Varna Bay...
Some essential phytochemicals and the antioxidant potential in fresh and dried persimmonSoon Teck Jung
Department of Food Engineering, Mokpo National University, Republic of Korea
Int J Food Sci Nutr 56:105-13. 2005..9535 and 0.9934). In conclusion, both fresh and dried persimmon possess high contents of bioactive compounds and have a high antioxidant potential. When fresh fruits are not available, proper dried persimmon can be successfully used...
In vitro studies of polyphenols, antioxidants and other dietary indices in kiwifruit (Actinidia deliciosa)Yong-Seo Park
Department of Horticultural Science, Mokpo National University, Muan Jeonnam, Korea
Int J Food Sci Nutr 57:107-22. 2006..It shortens the ripening time and improves fruit quality by decreasing its flesh firmness and acidity. Some minor changes in the protein profile did not affect the fruit taste and quality...
Comparative study of health properties and nutritional value of durian, mangosteen, and snake fruit: experiments in vitro and in vivoRatiporn Haruenkit
Faculty of Agricultural Industry and Department of Soil Science, King Mongkut s Institute of Technology Ladkrabang, Ladkrabang, Bangkok 10520, Thailand
J Agric Food Chem 55:5842-9. 2007..The nutritional values were comparably high. In conclusion, it could be suggested that inclusion of studied tropical fruits, especially durian, in known disease-preventing diets could be beneficial...
Effect of ethylene treatment on kiwifruit bioactivityYong-Seo Park
Department of Horticultural Science, Mokpo National University, Muan Jeonnam, Korea
Plant Foods Hum Nutr 61:151-6. 2006....
The effect of short-term lyophilized beer consumption on established hypertension in ratsZenon Jastrzebski
Department of Pharmacology, National Institute of Public Health, Chelmska str 30 34, 00 725 Warsaw, Poland
Food Chem Toxicol 45:296-302. 2007..In addition, in both animal strains there was an apparent inverse association between LB intake and body weight gains...
