Ruth Gallily

Summary

Affiliation: The Hebrew University
Country: Israel

Publications

  1. ncbi request reprint Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells
    Ruth Gallily
    The Lautenberg Center for General and Tumor Immunology, The Hebrew University Medical Faculty, Ein Kerem Campus, Jerusalem 1120, Israel
    Leuk Lymphoma 44:1767-73. 2003
  2. ncbi request reprint A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells
    Natalya M Kogan
    Department of Medicinal Chemistry and Natural Products, Medical Faculty, The Hebrew University, Jerusalem 91120, Israel
    Mol Pharmacol 70:51-9. 2006
  3. ncbi request reprint Cannabidiol: an overview of some pharmacological aspects
    Raphael Mechoulam
    Deportment of Medicinal Chemistry and Natural Products, Hebrew University of Jerusalem, Israel
    J Clin Pharmacol 42:11S-19S. 2002
  4. ncbi request reprint A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis
    Percy F Sumariwalla
    Kennedy Institute of Rheumatology, Imperial College London, London, UK
    Arthritis Rheum 50:985-98. 2004
  5. ncbi request reprint New cannabidiol derivatives: synthesis, binding to cannabinoid receptor, and evaluation of their antiinflammatory activity
    Shimon Ben-Shabat
    Department of Pharmacology and School of Pharmacy, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    J Med Chem 49:1113-7. 2006
  6. pmc N-arachidonoyl L-serine, an endocannabinoid-like brain constituent with vasodilatory properties
    Garry Milman
    Department of Medicinal Chemistry and Natural Products, Medical Faculty, and Laboratory of Environmental Physiology, Faculty of Dental Medicine, Hebrew University, Jerusalem 91120, Israel
    Proc Natl Acad Sci U S A 103:2428-33. 2006
  7. pmc Cannabidiol arrests onset of autoimmune diabetes in NOD mice
    Lola Weiss
    Department of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah Hebrew University Hospital, Jerusalem 91120, Israel
    Neuropharmacology 54:244-9. 2008
  8. ncbi request reprint Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury
    Ronen Durst
    Cardiology Department, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Am J Physiol Heart Circ Physiol 293:H3602-7. 2007
  9. ncbi request reprint Delta 9-tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells
    Gil Galanti
    The Mina and Everard Goodman Faculty of Life Science, Bar Ilan University, Ramat Gan, Israel
    Acta Oncol 47:1062-70. 2008

Collaborators

  • R Mechoulam
  • Arie Dagan
  • Manuel Guzman
  • Natalya M Kogan
  • Shimon Ben-Shabat
  • P Pacher
  • E Fride
  • Lola Weiss
  • Gil Galanti
  • Ronen Durst
  • Garry Milman
  • Percy F Sumariwalla
  • Gad Lavie
  • Shimon Slavin
  • Gideon Rechavi
  • Shoshana Reich
  • Amos Toren
  • Jacob Shoham
  • Ninette Amariglio
  • Michael Zeira
  • Tamar Fisher
  • Iris Kventsel
  • Itamar Raz
  • Keren Meir
  • Etty Grad
  • Thea Pugatsch
  • Ronen Beeri
  • Elizabet Tarsish
  • Haim Danenberg
  • Chaim Lotan
  • Yehoshua Maor
  • Sandor Batkai
  • Laszlo Offertaler
  • Saleh Abu-Lafi
  • Michal Horowitz
  • George Kunos
  • Fong Ming Mo
  • Susanna Tchilibon
  • Marc Feldmann

Detail Information

Publications9

  1. ncbi request reprint Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells
    Ruth Gallily
    The Lautenberg Center for General and Tumor Immunology, The Hebrew University Medical Faculty, Ein Kerem Campus, Jerusalem 1120, Israel
    Leuk Lymphoma 44:1767-73. 2003
    ..Caspase-3 activation was observed after the cannabinoid treatment, and may represent a mechanism for the apoptosis. Our data suggest a possible new approach to treatment of AML...
  2. ncbi request reprint A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells
    Natalya M Kogan
    Department of Medicinal Chemistry and Natural Products, Medical Faculty, The Hebrew University, Jerusalem 91120, Israel
    Mol Pharmacol 70:51-9. 2006
    ..A significant decrease in the total area occupied by vessels in HU-331-treated tumors was also observed. These data lead us to consider HU-331 to have high potential as a new antiangiogenic and anticancer drug...
  3. ncbi request reprint Cannabidiol: an overview of some pharmacological aspects
    Raphael Mechoulam
    Deportment of Medicinal Chemistry and Natural Products, Hebrew University of Jerusalem, Israel
    J Clin Pharmacol 42:11S-19S. 2002
    ..It is possible that, in part at least, its effects are due to its recently discovered inhibition of anandamide uptake and hydrolysis and to its antioxidative effect...
  4. ncbi request reprint A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis
    Percy F Sumariwalla
    Kennedy Institute of Rheumatology, Imperial College London, London, UK
    Arthritis Rheum 50:985-98. 2004
    ....
  5. ncbi request reprint New cannabidiol derivatives: synthesis, binding to cannabinoid receptor, and evaluation of their antiinflammatory activity
    Shimon Ben-Shabat
    Department of Pharmacology and School of Pharmacy, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    J Med Chem 49:1113-7. 2006
    ..Surprisingly, we found that these derivatives exhibit good binding to CB(1). In addition hydrogenated CBD and CBD-DMH demonstrate bioactivities different from their original compounds...
  6. pmc N-arachidonoyl L-serine, an endocannabinoid-like brain constituent with vasodilatory properties
    Garry Milman
    Department of Medicinal Chemistry and Natural Products, Medical Faculty, and Laboratory of Environmental Physiology, Faculty of Dental Medicine, Hebrew University, Jerusalem 91120, Israel
    Proc Natl Acad Sci U S A 103:2428-33. 2006
    ..Many of these effects parallel those reported for abnormal cannabidiol (Abn-CBD), a synthetic agonist of a putative novel cannabinoid-type receptor. Hence, ARA-S may represent an endogenous agonist for this receptor...
  7. pmc Cannabidiol arrests onset of autoimmune diabetes in NOD mice
    Lola Weiss
    Department of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah Hebrew University Hospital, Jerusalem 91120, Israel
    Neuropharmacology 54:244-9. 2008
    ..Our data strengthen our previous assumption that CBD, known to be safe in man, can possibly be used as a therapeutic agent for treatment of type 1 diabetes...
  8. ncbi request reprint Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury
    Ronen Durst
    Cardiology Department, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Am J Physiol Heart Circ Physiol 293:H3602-7. 2007
    ..Inasmuch as CBD has previously been administered to humans without causing side effects, it may represent a promising novel treatment for myocardial ischemia...
  9. ncbi request reprint Delta 9-tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells
    Gil Galanti
    The Mina and Everard Goodman Faculty of Life Science, Bar Ilan University, Ramat Gan, Israel
    Acta Oncol 47:1062-70. 2008
    ..Here we used several experimental approaches, which identified delta-9-tetrahydrocannabinol (Delta(9)-THC) as an essential mediator of cannabinoid antitumoral action...