Richard P Ebstein

Summary

Affiliation: The Hebrew University
Country: Israel

Publications

  1. pmc The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis
    Robert D Oades
    Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Essen, Germany
    Behav Brain Funct 4:48. 2008
  2. doi Arginine vasopressin and oxytocin modulate human social behavior
    Richard P Ebstein
    Department of Psychology, The Hebrew University of Jerusalem, Herzog Memorial Hospital, Givat Shaul, Jerusalem, Israel
    Ann N Y Acad Sci 1167:87-102. 2009
  3. ncbi The molecular genetic architecture of human personality: beyond self-report questionnaires
    R P Ebstein
    Department of Psychology and Scheinfeld Center for Genetic Studies in the Social Sciences, Mount Scopus, Hebrew University, Jerusalem, Israel
    Mol Psychiatry 11:427-45. 2006
  4. ncbi Anorexia nervosa, perfectionism, and dopamine D4 receptor (DRD4)
    Rachel Bachner-Melman
    Department of Psychology, Mount Scopus, Hebrew University, Jerusalem, Israel
    Am J Med Genet B Neuropsychiatr Genet 144:748-56. 2007
  5. doi Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between
    Salomon Israel
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel
    Prog Brain Res 170:435-49. 2008
  6. pmc Epigenetic and genetic factors predict women's salivary cortisol following a threat to the social self
    Shany Edelman
    Department of Neurobiology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    PLoS ONE 7:e48597. 2012
  7. pmc All-trans retinoic acid upregulates reduced CD38 transcription in lymphoblastoid cell lines from Autism spectrum disorder
    Mathias Riebold
    Department of Human Genetics, Hebrew University, Jerusalem, Israel
    Mol Med 17:799-806. 2011
  8. doi Boys' serotonin transporter genotype affects maternal behavior through self-control: a case of evocative gene-environment correlation
    Roni Pener-Tessler
    Hebrew University of Jerusalem, Mount Scopus, Jerusalem 91905, Israel
    Dev Psychopathol 25:151-62. 2013
  9. pmc AVPR1A variant associated with preschoolers' lower altruistic behavior
    Reut Avinun
    Department of Neurobiology, The Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 6:e25274. 2011
  10. doi Association between arginine vasopressin 1a receptor (AVPR1a) promoter region polymorphisms and prepulse inhibition
    Raz Levin
    Neurobiology, Hebrew University, Jerusalem, Israel
    Psychoneuroendocrinology 34:901-8. 2009

Collaborators

Detail Information

Publications70

  1. pmc The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis
    Robert D Oades
    Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Essen, Germany
    Behav Brain Funct 4:48. 2008
    ..abstract:..
  2. doi Arginine vasopressin and oxytocin modulate human social behavior
    Richard P Ebstein
    Department of Psychology, The Hebrew University of Jerusalem, Herzog Memorial Hospital, Givat Shaul, Jerusalem, Israel
    Ann N Y Acad Sci 1167:87-102. 2009
    ..We expect that future studies will continue this advance and deepen our understanding of these complex events...
  3. ncbi The molecular genetic architecture of human personality: beyond self-report questionnaires
    R P Ebstein
    Department of Psychology and Scheinfeld Center for Genetic Studies in the Social Sciences, Mount Scopus, Hebrew University, Jerusalem, Israel
    Mol Psychiatry 11:427-45. 2006
    ....
  4. ncbi Anorexia nervosa, perfectionism, and dopamine D4 receptor (DRD4)
    Rachel Bachner-Melman
    Department of Psychology, Mount Scopus, Hebrew University, Jerusalem, Israel
    Am J Med Genet B Neuropsychiatr Genet 144:748-56. 2007
    ..Personality traits are potential endophenotypes for understanding the etiology of eating disorders and one of the several pathways to eating pathology may be mediated by the impact of DNA sequences on perfectionism...
  5. doi Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between
    Salomon Israel
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel
    Prog Brain Res 170:435-49. 2008
    ..Ultimately, investigators should strive to develop a cohesive model explaining how genomic variations are translated into individual and group differences in higher-order social behaviours...
  6. pmc Epigenetic and genetic factors predict women's salivary cortisol following a threat to the social self
    Shany Edelman
    Department of Neurobiology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    PLoS ONE 7:e48597. 2012
    ....
  7. pmc All-trans retinoic acid upregulates reduced CD38 transcription in lymphoblastoid cell lines from Autism spectrum disorder
    Mathias Riebold
    Department of Human Genetics, Hebrew University, Jerusalem, Israel
    Mol Med 17:799-806. 2011
    ..In conclusion, our results provide an empirical basis for the development of a pharmacological ASD treatment strategy based on retinoids...
  8. doi Boys' serotonin transporter genotype affects maternal behavior through self-control: a case of evocative gene-environment correlation
    Roni Pener-Tessler
    Hebrew University of Jerusalem, Mount Scopus, Jerusalem 91905, Israel
    Dev Psychopathol 25:151-62. 2013
    ..The implications of this evocative gene-environment correlation and the observed sex differences are discussed...
  9. pmc AVPR1A variant associated with preschoolers' lower altruistic behavior
    Reut Avinun
    Department of Neurobiology, The Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 6:e25274. 2011
    ..This finding helps further the understanding of the intricate mechanisms underlying early altruistic behavior...
  10. doi Association between arginine vasopressin 1a receptor (AVPR1a) promoter region polymorphisms and prepulse inhibition
    Raz Levin
    Neurobiology, Hebrew University, Jerusalem, Israel
    Psychoneuroendocrinology 34:901-8. 2009
    ..This is the first report in humans demonstrating a role of the AVPR1a gene in contributing to the PPI response to auditory stimuli...
  11. doi Defensive self-presentation style is associated with reduced prepulse inhibition
    Raz Levin
    Ezrath Nashim Herzog Memorial Hospital, Jerusalem, Israel
    Eur Neuropsychopharmacol 21:810-3. 2011
    ..Its findings suggest that very basic perceptual deficits that can be assessed using the PPI paradigm, may reflect information processing abnormalities that impact negatively upon the perception of complex social interactions...
  12. ncbi An examination of cognitive versus behavioral components of recovery from anorexia nervosa
    Rachel Bachner-Melman
    Department of Psychiatry, Hadassah University Medical Center, Ein Kerem, Jerusalem, Israel
    J Nerv Ment Dis 194:697-703. 2006
    ....
  13. doi Mothers' dopamine receptor polymorphism modulates the relation between infant fussiness and sensitive parenting
    Marsha Kaitz
    Department of Psychology, Hebrew University, Jerusalem 91905, Israel
    Dev Psychobiol 52:149-57. 2010
    ..Among those parents, sensitivity did not vary with infant temperament. This pattern of results indicates that mothers are differentially susceptible to infant fussiness, dependent on the presence of the 7-repeat DRD4 allele...
  14. pmc Human maternal behaviour is associated with arginine vasopressin receptor 1A gene
    Reut Avinun
    Department of Psychology, The Hebrew University of Jerusalem, Mount Scopus, Jerusalem 91905, Israel
    Biol Lett 8:894-6. 2012
    ..This finding advances our understanding of the genetic influences on human maternal behaviour...
  15. ncbi Association between the insulin-like growth factor 2 gene (IGF2) and scores on the Eating Attitudes Test in nonclinical subjects: a family-based study
    Rachel Bachner-Melman
    Scheinfeld Center for Human Genetics in the Social Sciences, Department of Psychology, Hebrew University, Jerusalem 91905, Israel
    Am J Psychiatry 162:2256-62. 2005
    ..This investigation extended these studies and investigated the psychological and behavioral implications of this hormone's impact on metabolism and body composition...
  16. doi Low CD38 expression in lymphoblastoid cells and haplotypes are both associated with autism in a family-based study
    Elad Lerer
    Human Genetics, Hebrew University, Jerusalem, Israel
    Autism Res 3:293-302. 2010
    ..This prompted us to both examine CD38 expression in human lymphoblastoid cell lines (LBC) as well as to test association between SNPs across the CD38 gene and ASD...
  17. pmc The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task
    Salomon Israel
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 4:e5535. 2009
    ..In the current investigation, the gene encoding the related oxytocin receptor (OXTR) was tested for association with the DG and a related paradigm, the Social Values Orientation (SVO) task...
  18. pmc Differential genetic susceptibility to child risk at birth in predicting observed maternal behavior
    Keren Fortuna
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 6:e19765. 2011
    ....
  19. ncbi The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task
    Salomon Israel
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel
    PLoS ONE 4:e5535. 2009
    ....
  20. doi BDNF Val66Met polymorphism is associated with HPA axis reactivity to psychological stress characterized by genotype and gender interactions
    Idan Shalev
    Neurobiology, Hebrew University, Jerusalem, Israel
    Psychoneuroendocrinology 34:382-8. 2009
    ..Gender differences in BDNFxstress responses were posited because estrogen induces synthesis of BDNF in several brain regions...
  21. doi Vasopressin needs an audience: neuropeptide elicited stress responses are contingent upon perceived social evaluative threats
    Idan Shalev
    Neurobiology, Hebrew University, Jerusalem, 91501, Israel
    Horm Behav 60:121-7. 2011
    ....
  22. doi Genetics of human social behavior
    Richard P Ebstein
    Department of Psychology, The Hebrew University of Jerusalem, Jerusalem 91905, Israel
    Neuron 65:831-44. 2010
    ..Other polymorphic genes constituting the "usual suspects"--i.e., those encoding for dopamine reward pathways, serotonergic emotional regulation, or sex hormones--further enable elaborate social behaviors...
  23. pmc AVPR1a and SLC6A4 gene polymorphisms are associated with creative dance performance
    Rachel Bachner-Melman
    Department of Psychology, Mount Scopus, Hebrew University, Jerusalem, Israel
    PLoS Genet 1:e42. 2005
    ....
  24. doi Hypnotizability is associated with a protective but not acquisitive self-presentation style
    Raz Levin
    Herzog Memorial Hospital, Jerusalem, Israel
    Int J Clin Exp Hypn 61:183-92. 2013
    ..43, p = .002) but not between hypnotizability and RSMS (r = .070, p = .631). These results suggest that a protective self-presentation style may incline certain individuals to cooperate with hypnotic suggestions...
  25. doi Oxytocin, but not vasopressin, increases both parochial and universal altruism
    Salomon Israel
    Department of Psychology and Center for the Study of Rationality, Hebrew University, Jerusalem 91501, Israel
    Psychoneuroendocrinology 37:1341-4. 2012
    ..In contrast, participants receiving vasopressin did not differ from those receiving placebo in their cooperative behavior. Our results highlight the selective role of oxytocin in intergroup cooperative behavior...
  26. doi Heritability of children's prosocial behavior and differential susceptibility to parenting by variation in the dopamine receptor D4 gene
    Ariel Knafo
    Psychology Department, Hebrew University of Jerusalem, Mount Scopus, Jerusalem 91905, Israel
    Dev Psychopathol 23:53-67. 2011
    ....
  27. doi Identification of a functional rare variant in autism using genome-wide screen for monoallelic expression
    Eyal Ben-David
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J Safra Campus, Jerusalem 91904, Israel
    Hum Mol Genet 20:3632-41. 2011
    ....
  28. ncbi How anorexic-like are the symptom and personality profiles of aesthetic athletes?
    Rachel Bachner-Melman
    Department of Psychology, Hebrew University of Jerusalem, Israel
    Med Sci Sports Exerc 38:628-36. 2006
    ..We tested the hypothesis that aesthetic athletes (AA) have anorexic-like eating attitudes and behaviors, share personality characteristics such as perfectionism and obsessiveness, and are at high risk of eating disorders...
  29. doi Vasopressin selectively impairs emotion recognition in men
    Florina Uzefovsky
    Psychology Department, Hebrew University, Jerusalem 91501, Israel
    Psychoneuroendocrinology 37:576-80. 2012
    ..The current report emphasizes the selective role of AVP in male emotional perception and empathy, a core element in all human social interactions...
  30. ncbi Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking
    R P Ebstein
    Research Laboratory, S Herzog Memorial Hospital, Jerusalem, Israel
    Nat Genet 12:78-80. 1996
  31. doi Hypnotizability and sensorimotor gating: a dopaminergic mechanism of hypnosis
    Raz Levin
    Department of Psychiatry, Herzog Memorial Hospital, Givat Shaul, Jerusalem, Israel
    Int J Clin Exp Hypn 59:399-405. 2011
    ....
  32. ncbi The relationship between selflessness levels and the severity of anorexia nervosa symptomatology
    Rachel Bachner-Melman
    Psychology Department, Hebrew University of Jerusalem, Israel
    Eur Eat Disord Rev 15:213-20. 2007
    ..Recovered anorexics scored similarly to female controls. Assertion of one's own needs and interests may be an integral component of recovery from AN, and should be emphasized in therapy...
  33. ncbi Hypnotic susceptibility: multidimensional relationships with Cloninger's Tridimensional Personality Questionnaire, COMT polymorphisms, absorption, and attentional characteristics
    Pesach Lichtenberg
    S Herzog Memorial Hospital, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Int J Clin Exp Hypn 52:47-72. 2004
    ..1%) and highly (81.5%) hypnotizable groups. These results suggest that highly hypnotizable persons have a more effective frontolimbic attentional system and further suggest the involvement of dopaminergic systems in hypnotizability...
  34. doi Intranasal oxytocin modulates EEG mu/alpha and beta rhythms during perception of biological motion
    Anat Perry
    The Department of Psychology, Hebrew University of Jerusalem, Mt Scopus, 91905 Jerusalem, Israel
    Psychoneuroendocrinology 35:1446-53. 2010
    ..These results are a first step linking OT to the modulation of EEG rhythms in humans, suggesting that OT may have a role in allocating cortical resources to social tasks partly mediated by mirror neuron activity...
  35. doi Self-monitoring in anorexia nervosa
    Rachel Bachner-Melman
    Psychology, Hebrew University of Jerusalem, Israel
    Int J Soc Psychiatry 55:170-9. 2009
    ..A possible connection between Mark Snyder's concept of self-monitoring and anorexia nervosa (AN) has not previously been examined...
  36. ncbi Why do young women smoke? II. Role of traumatic life experience, psychological characteristics and serotonergic genes
    E Lerer
    Research Laboratory, Sara Herzog Memorial Hospital, Jerusalem, Israel
    Mol Psychiatry 11:771-81. 2006
    ..29, P=0.01) was a significant risk factor for HND. Further studies should consider the interactive contribution of life events and relevant gene variants to cigarette smoking and other complex behavioral traits...
  37. ncbi A meta-analysis of the association between DRD4 polymorphism and novelty seeking
    A N Kluger
    School of Business Administration, The Hebrew University of Jerusalem, Mt Scopus, Jerusalem, Israel
    Mol Psychiatry 7:712-7. 2002
    ..The growing availability of powerful statistical techniques, high-throughput genotyping and large numbers of polymorphic markers such as single nucleotide polymorphisms makes such proposed studies increasingly feasible...
  38. doi The Broad Autism Phenotype Questionnaire: mothers versus fathers of children with an autism spectrum disorder
    Ifat Seidman
    Department of Psychology, Hebrew University of Jerusalem, Mount Scopus, 91905 Jerusalem, Israel
    J Autism Dev Disord 42:837-46. 2012
    ..Results are discussed in reference to sex differences in BAP-related characteristics in parents of children with autism...
  39. doi The contributions of oxytocin and vasopressin pathway genes to human behavior
    Richard P Ebstein
    Department of Psychology, National University of Singapore, Singapore
    Horm Behav 61:359-79. 2012
    ..This article is part of a Special Issue entitled Oxytocin, Vasopressin, and Social Behavior...
  40. ncbi Acetylcholinesterase/paraoxonase interactions increase the risk of insecticide-induced Parkinson's disease
    Liat BenMoyal-Segal
    The Life Sciences Institute, The Hebrew University of Jerusalem, Israel
    FASEB J 19:452-4. 2005
    ..Our findings suggest that inherited interactive weakness of AChE and PON1 expression increases the insecticide-induced occurrence of Parkinson's disease...
  41. ncbi Family-based and population study of a functional promoter-region monoamine oxidase A polymorphism in autism: possible association with IQ
    Nurit Yirmiya
    Department of Psychology, Hebrew University of Jerusalem, Jerusalem, Israel
    Am J Med Genet 114:284-7. 2002
    ..5, P = 0.046, N = 28) in the small group of autism subjects recruited from families with two affected siblings...
  42. ncbi Dopamine D4 receptor and serotonin transporter promoter in the determination of neonatal temperament
    R P Ebstein
    Research Laboratory, S Herzog Memorial Hospital, Jerusalem, Israel
    Mol Psychiatry 3:238-46. 1998
    ....
  43. ncbi Additional evidence for an association between the dopamine D4 receptor (D4DR) exon III repeat polymorphism and the human personality trait of Novelty Seeking
    R P Ebstein
    Research Laboratory, S Herzog Memorial Hospital, Jerusalem, Israel
    Mol Psychiatry 2:472-7. 1997
    ....
  44. doi Research review: crossing syndrome boundaries in the search for brain endophenotypes
    Yonata Levy
    Psychology Department, Hebrew University, Jerusalem, Israel
    J Child Psychol Psychiatry 50:657-68. 2009
    ..Cohort selection should rest on behavioral homogeneity, enabling, when necessary, syndrome heterogeneity...
  45. ncbi Association between a vasopressin receptor AVPR1A promoter region microsatellite and eating behavior measured by a self-report questionnaire (Eating Attitudes Test) in a family-based study of a nonclinical population
    Rachel Bachner-Melman
    Department of Psychology, Mount Scopus, Hebrew University, Jerusalem, Israel
    Int J Eat Disord 36:451-60. 2004
    ....
  46. ncbi Personality and polymorphisms of genes involved in aminergic neurotransmission
    R P Ebstein
    Research Laboratory, S Herzog Memorial Hospital, P O Box 35300, 91351, Jerusalem, Israel
    Eur J Pharmacol 410:205-214. 2000
    ..It should soon be possible to identify many of the genes contributing to specific personality traits and to better define their role in determining normal and abnormal behavior from early development through adulthood...
  47. doi The sorting test of the D-KEFS in current and weight restored anorexia nervosa patients
    Eyal Heled
    Day Treatment Rehabilitation Unit, Sheba Medical Center, Ramat Gan, Israel Department of Psychology, Hebrew University, Jerusalem, Israel
    Int J Eat Disord 47:92-8. 2014
    ..The aim of this study is to further examine EF in women with past and present AN and to compare their performances in verbal and visual modalities with women who have never suffered from an eating disorder...
  48. ncbi High glycine levels are associated with prepulse inhibition deficits in chronic schizophrenia patients
    Uriel Heresco-Levy
    Psychiatry and Research Department, Ezrath Nashim Herzog Memorial Hospital, P O Box 3900, Givat Shaul 91351, Jerusalem, Israel
    Schizophr Res 91:14-21. 2007
    ..4, p=0.03). These preliminary findings indirectly support previous observations on ketamine effects upon PPI in humans and suggest a dissociation of symptomatology and PPI changes as function of NMDAR modulation in schizophrenia...
  49. ncbi An update on molecular genetic studies of human personality traits
    Richard P Ebstein
    S Herzog Memorial Hospital and Psychology Department, Scheinfeld Center, Hebrew University, Jerusalem, Israel
    Appl Bioinformatics 1:57-68. 2002
    ....
  50. ncbi Evidence for an association with the serotonin transporter promoter region polymorphism and autism
    N Yirmiya
    Hebrew University of Jerusalem, Jerusalem, Israel
    Am J Med Genet 105:381-6. 2001
    ....
  51. ncbi No association between the serotonin transporter gene regulatory region polymorphism and the Tridimensional Personality Questionnaire (TPQ) temperament of harm avoidance
    R P Ebstein
    Research Laboratory, S Herzog Memorial Hospital, Jerusalem, Israel
    Mol Psychiatry 2:224-6. 1997
    ....
  52. ncbi Association between the oxytocin receptor (OXTR) gene and autism: relationship to Vineland Adaptive Behavior Scales and cognition
    E Lerer
    Department of Human Genetics, Hebrew University, Jerusalem, Israel
    Mol Psychiatry 13:980-8. 2008
    ....
  53. ncbi Association between the arginine vasopressin 1a receptor (AVPR1a) gene and autism in a family-based study: mediation by socialization skills
    N Yirmiya
    Department of Psychology, Hebrew University, Jerusalem, Israel
    Mol Psychiatry 11:488-94. 2006
    ..Molecular Psychiatry (2006) 11, 488-494. doi:10.1038/sj.mp.4001812; published online 7 March 2006...
  54. ncbi Exploratory association study between catechol-O-methyltransferase (COMT) high/low enzyme activity polymorphism and hypnotizability
    P Lichtenberg
    S Herzog Memorial Hospital, Jerusalem, Israel
    Am J Med Genet 96:771-4. 2000
    ..This association was significant for men but not for women. As for all case-control studies, these results need to be interpreted cautiously and require replication. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:771-774, 2000...
  55. ncbi No association between the dopamine D3 receptor Bal I polymorphism and schizophrenia in a family-based study of a Palestinian Arab population
    I Kremer
    Department of Psychiatry, Emek Hospital, Afula, Israel
    Am J Med Genet 96:778-80. 2000
    ..38, P > 0.1, n = 86 families) for association/linkage (or increased homozygosity) of the DRD3 Bal I polymorphism to schizophrenia in our sample. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:778-780, 2000...
  56. ncbi Family-based association study of the serotonin transporter promoter region polymorphism (5-HTTLPR) in attention deficit hyperactivity disorder
    I Manor
    Geha Mental Health Center, Petak Tikvah, Israel
    Am J Med Genet 105:91-5. 2001
    ..Similar results were observed when allele frequencies were compared (likelihood ratio = 3.81, P = 0.05, n = 136 alleles). These first findings should be interpreted cautiously until replicated in independently recruited clinical samples...
  57. ncbi The short DRD4 repeats confer risk to attention deficit hyperactivity disorder in a family-based design and impair performance on a continuous performance test (TOVA)
    I Manor
    Geha Mental Health Center, Petak Tikvah, Israel
    Mol Psychiatry 7:790-4. 2002
    ....
  58. ncbi Relationship between dopamine system genes and extraversion and novelty seeking
    V E Golimbet
    Scientific Center for Mental Health, Russian Academy of Medical Sciences, Moscow
    Neurosci Behav Physiol 37:601-6. 2007
    ..These results are consistent with current theoretical concepts of the regulation of dopamine transmission in the brain...
  59. ncbi An association between fibromyalgia and the dopamine D4 receptor exon III repeat polymorphism and relationship to novelty seeking personality traits
    D Buskila
    Mol Psychiatry 9:730-1. 2004
  60. ncbi Polymorphisms in the dopamine D4 receptor gene (DRD4) contribute to individual differences in human sexual behavior: desire, arousal and sexual function
    I Z Ben Zion
    Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Mol Psychiatry 11:782-6. 2006
    ....
  61. ncbi Dopaminergic polymorphisms associated with self-report measures of human altruism: a fresh phenotype for the dopamine D4 receptor
    R Bachner-Melman
    Mol Psychiatry 10:333-5. 2005
  62. ncbi Transmission disequilibrium and haplotype analyses of the G72/G30 locus: suggestive linkage to schizophrenia in Palestinian Arabs living in the North of Israel
    M Korostishevsky
    Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel 69978
    Am J Med Genet B Neuropsychiatr Genet 141:91-5. 2006
    ..These data suggest a common risk factor for schizophrenia susceptibility in the G72/G30 locus among Ashkenazi Jews and Palestinian Arabs. The results strengthen previous reports on the role of this locus in the etiology of schizophrenia...
  63. ncbi [Polymorphic markers of the dopamine D4 receptor gene promoter region and personality traits in mentally healthy individuals from the Russian population]
    V E Golimbet
    Genetika 41:966-72. 2005
    ..We have shown that the traits in question were mainly related to social activity. A reduction in social activity is associated largely with the T(-521 C/T) allele, characterized by low transcription rate...
  64. ncbi Confirmation of an excess of the high enzyme activity COMT val allele in heroin addicts in a family-based haplotype relative risk study
    R Horowitz
    Kfar Malkishua Association, Beersheva, Israel
    Am J Med Genet 96:599-603. 2000
    ..9, P = 0.019, df = 2, n = 1,422 alleles) suggesting that population stratification is responsible for our failure to observe an excess of the COMT val allele when using the case-control design...
  65. ncbi No evidence for linkage by transmission disequilibrium test analysis of microsatellite marker D22S278 and schizophrenia in a Palestinian Arab and in a German population
    M Dobrusin
    Beersheva Mental Health Center, Beersheva, Israel
    Am J Med Genet 105:328-31. 2001
    ..11, P = 0.12, df = 9; Beersheva: chi-square = 7.04, P = 0.32, df = 6). Additionally, we examined D22S278 in a group of 114 schizophrenic German triads and failed to observe evidence for linkage (chi-square = 8.13, P = 0.42, df = 8df)...
  66. ncbi A family-based study of the Cys23Ser 5HT2C serotonin receptor polymorphism in schizophrenia
    I Murad
    Dr. Kemal Psychiatric Hospital, Bethlehem, Palestine
    Am J Med Genet 105:236-8. 2001
    ..No evidence was obtained for preferential transmission of the Cys23Ser 5HT2C alleles in schizophrenia in either of the two main ethnic groups examined (German and Palestinian Arab) or in the combined cohort (TDT chi-square = 0.00, NS)...
  67. ncbi Family-based and association studies of monoamine oxidase A and attention deficit hyperactivity disorder (ADHD): preferential transmission of the long promoter-region repeat and its association with impaired performance on a continuous performance test (T
    I Manor
    Geha Mental Health Center, Petak Tikvah, Israel
    Mol Psychiatry 7:626-32. 2002
    ..88, P= 0.0007, 2 df). All three complementary approaches employed (family-based, case-control and quantitative trait design) suggest a role for the MAO A promoter-region polymorphism in conferring risk for ADHD in our patient population...
  68. ncbi Family-based and case-control study of catechol-O-methyltransferase in schizophrenia among Palestinian Arabs
    I Kremer
    Emek Hospital, Afula, Israel
    Am J Med Genet B Neuropsychiatr Genet 119:35-9. 2003
    ..In summary, by case-control design but not by a family-based study, there is a weak effect in female patients of the high activity COMT allele in conferring risk for schizophrenia...
  69. ncbi Maternal transmission disequilibrium of the glutamate receptor GRIK2 in schizophrenia
    J Bah
    Human Genetics and Cognitive Functions, Universite Paris 7, Institut Pasteur, 25, rue du Docteur Roux, 75724 Paris Cedex 15, France
    Neuroreport 15:1987-91. 2004
    ..05). These results are similar to the maternal GRIK2 transmission disequilibrium previously reported for autism, and support the presence of a susceptibility gene for schizophrenia at 6q16...
  70. ncbi Examination of IMPA1 and IMPA2 genes in manic-depressive patients: association between IMPA2 promoter polymorphisms and bipolar disorder
    G Sjøholt
    Dr Einar Martens Research Group for Biological Psychiatry and Locus on Neuroscience, Center for Medical Genetics and Molecular Medicine, University of Bergen, Norway
    Mol Psychiatry 9:621-9. 2004
    ..The association between manic-depressive illness and IMPA2 variants supports several reports on the linkage of bipolar disorder to chromosome 18p11.2, and sustains the possible role of IMPA2 as a susceptibility gene in bipolar disorder...