R Benoliel

..The clinical pharmacology of topiramate, which is reviewed, includes enhanced neuronal stability and neuroprotection, making it a possible candidate in the treatment of painful orofacial neuropathies...

..71 and a NPV = 0.95. Expansion of the IHS system is needed so as to integrate more orofacial pain syndromes...

..The treatment of painful neuropathies is difficult and carries a poor prognosis. Based on the available literature on efficacy and side effects, we propose a treatment algorithm for traumatic trigeminal neuropathies...

..To field-test carefully designed criteria for pain following trigeminal nerve trauma...

..However, we propose the concept that because COFP and headaches share underlying pathophysiological mechanisms, clinical characteristics, and neurovascular anatomy, they should be classified together...

..To document the neurosensory changes in the infraorbital nerve following zygomatic fractures managed in various ways...

..To assess whether pain-related awakenings occur with persistent orofacial pain conditions and whether it is related to pain severity...

..Clinically this may mean reduced side effects. Additionally the potential of topiramate as a neuroprotectant is studied and, although the results were negative, this area needs further research...

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..The aim of this study was to test the temporal definitions of chronic daily headache (CDH) in an orofacial pain population and examine the features of the so-defined chronic orofacial pain (COFP)...

..to assess the prevalence of headaches and painful tempormandibular disorders (TMDs) and examine these via demographic and specific lifestyle parameters, as well as examine the relationship among TMDs, headaches, and depression rates...

..Cases secondary to trauma, systemic disease, and nervous system pathology have been described in the literature, and the clinician must exclude these possible causes. A thorough knowledge of this entity is therefore essential...

..This study confirms previous work that found no sympathetic invasion of TG following injury, and shows that this finding is unaffected by the presence or absence of nerve injury induced hyperresponsiveness...

..The possible roles of NPY in pain modulation and nerve injury are discussed in light of these findings...

..In this context it is widely accepted that a complex interaction of variable intrinsic and extrinsic factors act to induce POMP and dysfunction...

..05) and mechanohyperalgesia (14th and 17th dpo, unpaired t-test, P<0.05), following a second sciatic nerve CCI relative to the control group. This effect was not observed in Sprague-Dawley or Sabra rats...

..To assess the effects of four- and six-point acupuncture on facial sensory detection thresholds to thermal and electrical stimuli...

..This model of inflammation-induced neuropathic pain is highly applicable to the study of neuroinflammatory orofacial pain...

..Additionally, pain is frequent in cancer management protocols (surgery, chemotherapy, and radiotherapy). Understanding the mechanisms involved in cancer-related orofacial pain will enhance patient management...

..04, respectively). This study clearly shows that perineural inflammation with no axonal nerve damage induced by CFA application around the nerve trunk elevates spontaneous activity and induces mechanosensitivity in myelinated axons...

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..The aim of this study was to compare the oral mucosal pH in healthy individuals to patients with gastroesophageal reflux disease (GERD), Bulimia nervosa (BN) and burning mouth syndrome (BMS)...

..These cases responded to antineuralgic therapy with concomitant resolution of lacrimation and were clinically very similar to TN. The differential diagnosis and the possibility of lacrimation in TN are discussed...

..Conversely, a trial with indomethacin abolished the late-onset headache, but not the immediate neuralgic-type pain. The independent nature of these pains suggests different pathophysiological mechanisms which are discussed...

..In patients with muscle-related facial pain there was significant elevation of the electrical detection threshold in the AUT region...

..Inflammatory neuritis is an early expression of malignancy and may play a role in chronic cancer-related pain initiation and additionally may offer diagnostic opportunities...

..No malignancy was found in the remaining 11 patients. CONCLUSIONS: A-beta primary afferent hypersensitivity is observed to occur in nerves exposed to soft tissue oral malignancy...

..ii) To assess correlations between whole-saliva cortisol and some clinical manifestations in patients with SjS...

..Treatment of primary vascular-type craniofacial pain depends on its more specific diagnosis, and may be abortive or prophylactic. Diagnostic features, common pathophysiological mechanisms, and treatment modalities are discussed...

..Understanding the mechanisms involved in chronic pain enables the clinician to skillfully apply this knowledge when selecting a therapy...

..To establish the normal range of oral mucosal pH and to correlate these measurements to salivary flow rate in healthy individuals according to age and gender...

..A brief summary of the American as well as the British recommendations for adults and children is reported...

..The review focuses on medical management, as well as surgical and other interventions for painful neuropathies...

..In this article specific clinical uses of QST are described and its clinical applicability is demonstrated. Future studies should be directed at exploring the use of QST in the diagnosis and classification of further nerve pathologies...

..The objective of this study was to analyze the etiological factors and neurosensory signatures of patients attending with a primary complaint of numb chin...

..More than two-thirds of patients with burning mouth syndrome (BMS) have altered taste sensation. The authors conducted a study to assess chorda tympani and trigeminal nerve function in these patients...