Yael Ziv

Summary

Affiliation: Tel Aviv University
Country: Israel

Publications

  1. ncbi request reprint Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway
    Yael Ziv
    The David and Inez Myers Laboratory for Genetic Research, Department of Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Nat Cell Biol 8:870-6. 2006
  2. ncbi request reprint The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
    Yosef Shiloh
    The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Nat Rev Mol Cell Biol 14:197-210. 2013
  3. doi request reprint The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
    Yosef Shiloh
    The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Nat Rev Mol Cell Biol 14:197-210. 2013
  4. doi request reprint ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage
    Ariel Bensimon
    David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Sci Signal 3:rs3. 2010
  5. ncbi request reprint Ataxia-telangiectasia: mild neurological presentation despite null ATM mutation and severe cellular phenotype
    Neora Alterman
    The David and Inez Myers Laboratory for Genetic Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Am J Med Genet A 143:1827-34. 2007
  6. ncbi request reprint Studying the cerebellar DNA damage response in the tissue culture dish
    Aya Tzur-Gilat
    The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Tel Aviv 69978, Israel
    Mech Ageing Dev 134:496-505. 2013
  7. pmc The ATM protein: the importance of being active
    Yosef Shiloh
    The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    J Cell Biol 198:273-5. 2012
  8. pmc Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks
    Adva Levy-Barda
    The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cell Cycle 10:4300-10. 2011
  9. doi request reprint ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
    Aaron A Goodarzi
    Genome Damage and Stability Centre, University of Sussex, East Sussex BN1 9RQ, UK
    Mol Cell 31:167-77. 2008

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway
    Yael Ziv
    The David and Inez Myers Laboratory for Genetic Research, Department of Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Nat Cell Biol 8:870-6. 2006
    ..These results suggest that chromatin relaxation is a fundamental pathway in the DNA-damage response and identify its primary mediators...
  2. ncbi request reprint The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
    Yosef Shiloh
    The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Nat Rev Mol Cell Biol 14:197-210. 2013
    ..Moreover, it has become apparent that ATM is active in other cell signalling pathways involved in maintaining cellular homeostasis...
  3. doi request reprint The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
    Yosef Shiloh
    The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Nat Rev Mol Cell Biol 14:197-210. 2013
    ..Moreover, it has become apparent that ATM is active in other cell signalling pathways involved in maintaining cellular homeostasis...
  4. doi request reprint ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage
    Ariel Bensimon
    David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Sci Signal 3:rs3. 2010
    ..It reveals insights into the breadth and complexity of the cellular responses involved in the coordination of many DDR pathways, which is in line with the critical importance of genomic stability in maintenance of cellular homeostasis...
  5. ncbi request reprint Ataxia-telangiectasia: mild neurological presentation despite null ATM mutation and severe cellular phenotype
    Neora Alterman
    The David and Inez Myers Laboratory for Genetic Research, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Am J Med Genet A 143:1827-34. 2007
    ..This analysis shows that the severity of the neurological component of A-T is determined not only by ATM mutations but also by other influences yet to be found...
  6. ncbi request reprint Studying the cerebellar DNA damage response in the tissue culture dish
    Aya Tzur-Gilat
    The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Tel Aviv 69978, Israel
    Mech Ageing Dev 134:496-505. 2013
    ..Our results to date, which indicate special chromatin organization in Purkinje cells that affects certain pathways of the DDR, demonstrate the usefulness of cerebellar organotypic cultures for addressing the above questions. ..
  7. pmc The ATM protein: the importance of being active
    Yosef Shiloh
    The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    J Cell Biol 198:273-5. 2012
    ..This is surprising because mice completely lacking ATM have a much more moderate phenotype. The findings impact on basic cancer research and cancer therapeutics...
  8. pmc Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks
    Adva Levy-Barda
    The David and Inez Myers Laboratory for Cancer Genetics, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cell Cycle 10:4300-10. 2011
    ..Our data reveal a novel ATM-PA28γ-proteasome axis of the DDR that is required for timely coordination of DSB repair...
  9. doi request reprint ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
    Aaron A Goodarzi
    Genome Damage and Stability Centre, University of Sussex, East Sussex BN1 9RQ, UK
    Mol Cell 31:167-77. 2008
    ..These data suggest that the importance of ATM signaling for DSB repair increases as the heterochromatic component of a genome expands...