Research Topics
Genomes and GenesSpecies | Gabi SheferSummaryAffiliation: Tel Aviv University Country: Israel Publications
| Collaborators
|
Detail Information
Publications
Primary myogenic cells see the light: improved survival of transplanted myogenic cells following low energy laser irradiationGabi Shefer
Department of Cell and Development Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
Lasers Surg Med 40:38-45. 2008..This study aims at following the effects of low-energy-laser irradiation on the fate of implanted myoblasts...
Reduced satellite cell numbers and myogenic capacity in aging can be alleviated by endurance exerciseGabi Shefer
Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
PLoS ONE 5:e13307. 2010..The significance of these data is that they suggest that the endurance exercise-mediated boost in both satellite numbers and myogenic properties may improve myofiber maintenance in aging...
SVEP1 is a novel marker of activated pre-determined skeletal muscle satellite cellsGabi Shefer
Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel
Stem Cell Rev 6:42-9. 2010..The impact of this finding is that it may allow scrutinizing signals that affect differentiation commitment. Thus, holds a therapeutic potential for maladies that involve deregulated stem cell fate-decision...
Insights into chromatin remodelers in mesenchymal stem cells and differentiationDafna Benayahu
Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
Front Biosci 14:398-409. 2009..Elucidating the nature of cross talk between chromatin remodelers and master genes is important for identifying pathways that govern stem cell fate and lineage decision...
Insights into the transcriptional and chromatin regulation of mesenchymal stem cells in musculo-skeletal tissuesDafna Benayahu
Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
Ann Anat 191:2-12. 2009..Revealing the mechanisms of action of such factors will provide understanding of how transcription and chromatin regulatory factors function together to regulate stem cell lineage fate decision...
The effect of exercise on IGF-I on muscle fibers and satellite cellsGabi Shefer
Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Front Biosci (Elite Ed) 4:230-9. 2012..We first summarize in brief the basic biology of skeletal satellite cells; the types of exercise and the basic biology of IGF-I. We then discuss the interplay between IGF skeletal muscle and satellite cells...
Reflections on lineage potential of skeletal muscle satellite cells: do they sometimes go MAD?Gabi Shefer
Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel
Crit Rev Eukaryot Gene Expr 17:13-29. 2007..Last, we highlight evidence in favor of satellite cell plasticity and emerging hurdles restraining this hypothesis...
Reconstruction of cell lineage trees in miceAdam Wasserstrom
Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel
PLoS ONE 3:e1939. 2008..Lineage analysis based on somatic mutations enables performing high resolution reconstruction of lineage trees in mice and humans, which can provide fundamental insights to many aspects of their development and tissue maintenance...
Nestin-GFP reporter expression defines the quiescent state of skeletal muscle satellite cellsKenneth Day
Department of Biological Structure, University of Washington School of Medicine, Seattle, WA 98195, USA
Dev Biol 304:246-59. 2007..The NES-GFP model reveals unique transcriptional activity within quiescent satellite cells and permits novel insight into the heterogeneity of their molecular signatures...
Satellite-cell pool size does matter: defining the myogenic potency of aging skeletal muscleGabi Shefer
Department of Biological Structure, School of Medicine, University of Washington, Magnuson Health Sciences Center, Room G514, Box 357420, Seattle, WA 98195, USA
Dev Biol 294:50-66. 2006..This study suggests that the population of satellite cells that participate in myofiber maintenance during routine muscle utilization is not fully replenished throughout life...
Skeletal muscle satellite cells can spontaneously enter an alternative mesenchymal pathwayGabi Shefer
Department of Biological Structure, School of Medicine, University of Washington, Seattle, WA 98195, USA
J Cell Sci 117:5393-404. 2004..We conclude that satellite cells possess mesenchymal plasticity, being able to commit either to myogenesis or to a mesenchymal alternative differentiation (MAD) program...
Isolation and culture of skeletal muscle myofibers as a means to analyze satellite cellsGabi Shefer
Department of Biological Structure, School of Medicine, University of Washington, Seattle, USA
Methods Mol Biol 290:281-304. 2005..These protocols allow studies on the interplay between the myofiber and its associated satellite cells...
