Research Topics
Species | Saharon RossetSummaryAffiliation: Tel Aviv University Country: Israel Publications
| Collaborators
|
Detail Information
Publications
Maximum-likelihood estimation of site-specific mutation rates in human mitochondrial DNA from partial phylogenetic classificationSaharon Rosset
Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv, Israel
Genetics 180:1511-24. 2008..Potential extensions of our methodology include its application to estimation of mutation rates in other genetic regions, like Y chromosome short tandem repeats...
Dyskinesias in patients with Parkinson's disease: effect of the leucine-rich repeat kinase 2 (LRRK2) G2019S mutationGilad Yahalom
The Parkinson Disease and Movement Disorders Clinic, Sagol Neuroscience Center and Department of Neurology, Tel Aviv University, Israel
Parkinsonism Relat Disord 18:1039-41. 2012....
Comment on "the predictive capacity of personal genome sequencing"David Golan
Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv 69978, Israel
Sci Transl Med 4:135le4. 2012..Recalculation of the results in Roberts et al. shows that the true predictive capacity of genomes may be higher than their maximal estimates...
Weighted pooling--practical and cost-effective techniques for pooled high-throughput sequencingDavid Golan
School of Mathematical Sciences, Tel Aviv University, Tel Aviv, Israel
Bioinformatics 28:i197-206. 2012..Finally, we argue that weighted designs have enough power to facilitate detection of common alleles, so they can be used as a cornerstone of whole-exome sequencing projects...
Maximum likelihood estimation of locus-specific mutation rates in Y-chromosome short tandem repeatsOsnat Ravid-Amir
Department of Statistics and Operation Research, Tel Aviv, Israel
Bioinformatics 26:i440-5. 2010..Furthermore, we obtain mutation rate estimates for DYS388, DYS426, DYS457, three STRs for which there were no mutation rate measures until now...
The population genetics of chronic kidney disease: insights from the MYH9-APOL1 locusSaharon Rosset
Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv 69978, Israel
Nat Rev Nephrol 7:313-26. 2011..We describe the data sources, process of discovery, and reasons for initial misidentification of the candidate gene, as well as the lessons that can be learned for future population genetics research...
Accurate estimation of heritability in genome wide studies using random effects modelsDavid Golan
School of Mathematical Sciences, Tel Aviv University, Tel Aviv, Israel
Bioinformatics 27:i317-23. 2011..2010) have demonstrated that the heritability of height is much higher than the ~10% associated with identified genetic factors. However, Yang et al. (2010) relied on a heuristic for performing estimation in this model...
