Saharon Rosset

Summary

Affiliation: Tel Aviv University
Country: Israel

Publications

  1. ncbi Maximum-likelihood estimation of site-specific mutation rates in human mitochondrial DNA from partial phylogenetic classification
    Saharon Rosset
    Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv, Israel
    Genetics 180:1511-24. 2008
  2. ncbi Dyskinesias in patients with Parkinson's disease: effect of the leucine-rich repeat kinase 2 (LRRK2) G2019S mutation
    Gilad Yahalom
    The Parkinson Disease and Movement Disorders Clinic, Sagol Neuroscience Center and Department of Neurology, Tel Aviv University, Israel
    Parkinsonism Relat Disord 18:1039-41. 2012
  3. ncbi Comment on "the predictive capacity of personal genome sequencing"
    David Golan
    Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv 69978, Israel
    Sci Transl Med 4:135le4. 2012
  4. ncbi Weighted pooling--practical and cost-effective techniques for pooled high-throughput sequencing
    David Golan
    School of Mathematical Sciences, Tel Aviv University, Tel Aviv, Israel
    Bioinformatics 28:i197-206. 2012
  5. ncbi Maximum likelihood estimation of locus-specific mutation rates in Y-chromosome short tandem repeats
    Osnat Ravid-Amir
    Department of Statistics and Operation Research, Tel Aviv, Israel
    Bioinformatics 26:i440-5. 2010
  6. ncbi The population genetics of chronic kidney disease: insights from the MYH9-APOL1 locus
    Saharon Rosset
    Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv 69978, Israel
    Nat Rev Nephrol 7:313-26. 2011
  7. ncbi Accurate estimation of heritability in genome wide studies using random effects models
    David Golan
    School of Mathematical Sciences, Tel Aviv University, Tel Aviv, Israel
    Bioinformatics 27:i317-23. 2011

Detail Information

Publications7

  1. ncbi Maximum-likelihood estimation of site-specific mutation rates in human mitochondrial DNA from partial phylogenetic classification
    Saharon Rosset
    Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv, Israel
    Genetics 180:1511-24. 2008
    ..Potential extensions of our methodology include its application to estimation of mutation rates in other genetic regions, like Y chromosome short tandem repeats...
  2. ncbi Dyskinesias in patients with Parkinson's disease: effect of the leucine-rich repeat kinase 2 (LRRK2) G2019S mutation
    Gilad Yahalom
    The Parkinson Disease and Movement Disorders Clinic, Sagol Neuroscience Center and Department of Neurology, Tel Aviv University, Israel
    Parkinsonism Relat Disord 18:1039-41. 2012
    ....
  3. ncbi Comment on "the predictive capacity of personal genome sequencing"
    David Golan
    Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv 69978, Israel
    Sci Transl Med 4:135le4. 2012
    ..Recalculation of the results in Roberts et al. shows that the true predictive capacity of genomes may be higher than their maximal estimates...
  4. ncbi Weighted pooling--practical and cost-effective techniques for pooled high-throughput sequencing
    David Golan
    School of Mathematical Sciences, Tel Aviv University, Tel Aviv, Israel
    Bioinformatics 28:i197-206. 2012
    ..Finally, we argue that weighted designs have enough power to facilitate detection of common alleles, so they can be used as a cornerstone of whole-exome sequencing projects...
  5. ncbi Maximum likelihood estimation of locus-specific mutation rates in Y-chromosome short tandem repeats
    Osnat Ravid-Amir
    Department of Statistics and Operation Research, Tel Aviv, Israel
    Bioinformatics 26:i440-5. 2010
    ..Furthermore, we obtain mutation rate estimates for DYS388, DYS426, DYS457, three STRs for which there were no mutation rate measures until now...
  6. ncbi The population genetics of chronic kidney disease: insights from the MYH9-APOL1 locus
    Saharon Rosset
    Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv 69978, Israel
    Nat Rev Nephrol 7:313-26. 2011
    ..We describe the data sources, process of discovery, and reasons for initial misidentification of the candidate gene, as well as the lessons that can be learned for future population genetics research...
  7. ncbi Accurate estimation of heritability in genome wide studies using random effects models
    David Golan
    School of Mathematical Sciences, Tel Aviv University, Tel Aviv, Israel
    Bioinformatics 27:i317-23. 2011
    ..2010) have demonstrated that the heritability of height is much higher than the ~10% associated with identified genetic factors. However, Yang et al. (2010) relied on a heuristic for performing estimation in this model...