Talma Rosenthal

Summary

Affiliation: Tel Aviv University
Country: Israel

Publications

  1. doi request reprint Managing hypertension in the elderly in light of the changes during aging
    Talma Rosenthal
    Department of Physiology and Pharmacology, Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Blood Press 17:186-94. 2008
  2. doi request reprint Occupational stress and hypertension
    Talma Rosenthal
    Department of Physiology and Pharmacology, Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University, Israel
    J Am Soc Hypertens 6:2-22. 2012
  3. doi request reprint The effect of migration on hypertension and other cardiovascular risk factors: a review
    Talma Rosenthal
    Department of Physiology and Pharmacology, Hypertension Research Unit, Tel Aviv University, Sackler School of Medicine, Tel Aviv, Israel Electronic address
    J Am Soc Hypertens 8:171-91. 2014
  4. ncbi request reprint Contemplating the history of drug therapy for hypertension
    Talma Rosenthal
    The Hella Gertner Chair for Hypertension Research, Sackler School of Medicine, Tel Aviv University, Israel
    Blood Press 13:262-71. 2004
  5. ncbi request reprint Seasonal variations in blood pressure
    Talma Rosenthal
    Sackler School of Medicine, Tel Aviv University, Israel
    Am J Geriatr Cardiol 13:267-72. 2004
  6. ncbi request reprint Fixed-drug combinations as first-line treatment for hypertension
    Talma Rosenthal
    Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Prog Cardiovasc Dis 48:416-25. 2006
  7. ncbi request reprint Effect of lercanidipine on kidney microanatomy in Cohen-Rosenthal diabetic hypertensive rats
    Talma Rosenthal
    Department of Physiology and Pharmacology, Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Cardiovasc Pharmacol Ther 12:145-52. 2007
  8. doi request reprint Angiotensin inhibition and malignancies: a review
    T Rosenthal
    Department of Physiology and Pharmacology, Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Hum Hypertens 23:623-35. 2009
  9. ncbi request reprint The effects of S-allylmercaptocaptopril, the synthetic product of allicin and captopril, on cardiovascular risk factors associated with the metabolic syndrome
    Mor Oron-Herman
    Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Atherosclerosis 183:238-43. 2005
  10. doi request reprint Telmisartan ameliorates hyperglycemia and metabolic profile in nonobese Cohen-Rosenthal diabetic hypertensive rats via peroxisome proliferator activator receptor-gamma activation
    Firas Younis
    Hypertension Research Unit, Department of Physiology and Pharmacology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Metabolism 59:1200-9. 2010

Collaborators

Detail Information

Publications36

  1. doi request reprint Managing hypertension in the elderly in light of the changes during aging
    Talma Rosenthal
    Department of Physiology and Pharmacology, Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Blood Press 17:186-94. 2008
    ....
  2. doi request reprint Occupational stress and hypertension
    Talma Rosenthal
    Department of Physiology and Pharmacology, Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University, Israel
    J Am Soc Hypertens 6:2-22. 2012
    ..In this article, we review the literature on the subject, discussing the various methodologies, confounding variables, and suggested approaches for a healthier work environment...
  3. doi request reprint The effect of migration on hypertension and other cardiovascular risk factors: a review
    Talma Rosenthal
    Department of Physiology and Pharmacology, Hypertension Research Unit, Tel Aviv University, Sackler School of Medicine, Tel Aviv, Israel Electronic address
    J Am Soc Hypertens 8:171-91. 2014
    ..The literature documents these phenomena, and can serve as a wake-up call to what is becoming a major worldwide health issue as populations shift and peoples struggle to adapt. ..
  4. ncbi request reprint Contemplating the history of drug therapy for hypertension
    Talma Rosenthal
    The Hella Gertner Chair for Hypertension Research, Sackler School of Medicine, Tel Aviv University, Israel
    Blood Press 13:262-71. 2004
  5. ncbi request reprint Seasonal variations in blood pressure
    Talma Rosenthal
    Sackler School of Medicine, Tel Aviv University, Israel
    Am J Geriatr Cardiol 13:267-72. 2004
    ..It will also result in more personalized management of antihypertensive medications tailored to the individual...
  6. ncbi request reprint Fixed-drug combinations as first-line treatment for hypertension
    Talma Rosenthal
    Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Prog Cardiovasc Dis 48:416-25. 2006
    ....
  7. ncbi request reprint Effect of lercanidipine on kidney microanatomy in Cohen-Rosenthal diabetic hypertensive rats
    Talma Rosenthal
    Department of Physiology and Pharmacology, Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Cardiovasc Pharmacol Ther 12:145-52. 2007
    ..Lercanidipine also had beneficial effects on the renal vasculature, suggesting that the compound may be considered for treating hypertension associated with diabetes...
  8. doi request reprint Angiotensin inhibition and malignancies: a review
    T Rosenthal
    Department of Physiology and Pharmacology, Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Hum Hypertens 23:623-35. 2009
    ..However, the population studies are mostly inconclusive, although they do suggest a possible interaction between ACE genotypes and susceptibility to altered behaviour of certain tumours...
  9. ncbi request reprint The effects of S-allylmercaptocaptopril, the synthetic product of allicin and captopril, on cardiovascular risk factors associated with the metabolic syndrome
    Mor Oron-Herman
    Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Atherosclerosis 183:238-43. 2005
    ..We conclude that the combined molecule CPSSA integrates the anti-hypertensive, lipid-lowering, and homocysteine-reducing effects of both allicin and captopril, making it a potential cardiovascular protective agent...
  10. doi request reprint Telmisartan ameliorates hyperglycemia and metabolic profile in nonobese Cohen-Rosenthal diabetic hypertensive rats via peroxisome proliferator activator receptor-gamma activation
    Firas Younis
    Hypertension Research Unit, Department of Physiology and Pharmacology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    Metabolism 59:1200-9. 2010
    ..Therefore, in addition to its hypotensive effect, telmisartan demonstrated beneficial thiazolidinedione-like effects...
  11. doi request reprint Prophylactic treatment with telmisartan induces tissue-specific gene modulation favoring normal glucose homeostasis in Cohen-Rosenthal diabetic hypertensive rats
    Firas Younis
    Department of Physiology and Pharmacology, Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University 69978, Tel Aviv, Israel
    Metabolism 61:164-74. 2012
    ..Telmisartan blunted the development of hypertension, insulin resistance, and diabetes in prediabetic Cohen-Rosenthal diabetic hypertensive rats through pleiotropic activity, involving specific gene regulation of target organs...
  12. doi request reprint Renal and systemic effects of endothelin-1 in diabetic-hypertensive rats
    Cipy Hofman
    Hypertension Research Unit, Department of Physiology and Pharmacology, Sackler School of Medicine, Tel Aviv University, Israel
    Clin Exp Hypertens 33:444-54. 2011
    ..Furthermore, in the CRDH rats, the expected ET-1-induced medullary vasodilatation was abolished and even reversed into prolonged vasoconstriction...
  13. doi request reprint S-allyl-mercapto-captopril: a novel compound in the treatment of Cohen-Rosenthal diabetic hypertensive rats
    Firas Younis
    Department of Physiology and Pharmacology, Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Clin Hypertens (Greenwich) 12:451-5. 2010
    ..The authors conclude that the combined molecule CPSSA integrates the antihypertensive feature of both allicin and captopril, making it a potential antidiabetic and cardiovascular protective agent...
  14. ncbi request reprint Telmisartan in the treatment of Cohen-Rosenthal Diabetic Hypertensive rats: the benefit of PPAR-gamma agonism
    Firas Younis
    Department of Physiology and Pharmacology, Hypertension Research Unit, Sackler School of Medicine, Tel Aviv University, Aviv, Israel
    Clin Exp Hypertens 29:419-26. 2007
    ..Blood glucose levels fell rapidly in the treated animals and remained steady in controls. Results indicate that telmisartan is a prototype of a new approach to treating coexisting diabetes and hypertension...
  15. ncbi request reprint Endothelin A antagonist LU-135252 and trandolapril in the treatment of the Cohen-Rosenthal diabetic hypertensive rat
    Cipy Hofman
    The Hypertension Unit, Sackler Faculty of Medecine, Tel Aviv University, Tel Aviv, Israel
    Blood Press 14:114-9. 2005
    ....
  16. ncbi request reprint Effects of endothelin-1 on systemic and renal hemodynamics in hypertensive-diabetic rats (CRDH), diabetic rats (CDR), and hypertensive rats (SHR)
    Cipy Hofman
    The Hypertension Unit, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Cardiovasc Pharmacol 44:S191-4. 2004
    ..Furthermore, in the Cohen-Rosenthal diabetic hypertensive rats the expected endothelin- 1-induced medullary vasodilation was abolished and even reversed into prolonged vasoconstrictor response...
  17. ncbi request reprint Screening for hypertension in high school
    Naomi Nussinovitch
    Hypertension Unit, Chaim Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Clin Pediatr (Phila) 44:711-4. 2005
    ..Prevalence of hypertension, mostly primary, in a large cohort of students was 0.76%. Early screening is important for early interventions and reducing cardiovascular morbidity and mortality in adulthood...
  18. ncbi request reprint Risk reduction therapy for syndrome X: comparison of several treatments
    Mor Oron-Herman
    Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Am J Hypertens 18:372-8. 2005
    ..The present study compared the effects of antihypertensive, lipid-lowering, and insulin-sensitizing agents on the above-mentioned components of this metabolic syndrome...
  19. ncbi request reprint Oxidative stress in hypertensive,diabetic, and diabetic hypertensive rats
    Joseph Friedman
    A J Chorley Institute for Hypertension, Chaim Sheba Medical Center, Tel Aviv University, Sackler School of Medicine, Tel Hashomer, Israel
    Am J Hypertens 16:1049-52. 2003
    ..Reactive oxygen species play a key role in the formation of endothelial dysfunction accompanying diabetes mellitus, hypertension, and other cardiovascular diseases...
  20. ncbi request reprint Hyperhomocysteinemia as a component of syndrome X
    Mor Oron-Herman
    Sackler Faculty of Medicine, Tel Aviv University, Israel
    Metabolism 52:1491-5. 2003
    ..It is thus highly likely that hyperhomocysteinemia is an integral component of the human syndrome X as well, and thereby contributes to the overall high vascular risk associated with this condition...
  21. ncbi request reprint The effects of allicin on weight in fructose-induced hyperinsulinemic, hyperlipidemic, hypertensive rats
    Amitai Elkayam
    Chorley Hypertension Research Institute, Chaim Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Hashomer, Israel
    Am J Hypertens 16:1053-6. 2003
    ..Thus, it was considered important to assess its effect on the weight of the animals...
  22. ncbi request reprint Effect of treatment with lercanidipine on heart of Cohen-Rosenthal diabetic hypertensive rats
    Francesco Amenta
    Dipartimento di Scienze Farmacologiche e Medicina Sperimentale, Universita di Camerino, Via Scalzino 3, 62032 Camerino, Italy
    Hypertension 41:1330-5. 2003
    ..Treatment with lercanidipine countered hypertension-related cardiac and coronary changes, suggesting that this dihydropyridine-type Ca2+ antagonist may improve heart and coronary structure in diabetes associated with hypertension...
  23. ncbi request reprint The Framingham prediction rule is not valid in a European population of treated hypertensive patients
    Sylvie Bastuji-Garin
    Department of Public Health, Henri Mondor Hospital, AP HP, Paris XII University, Creteil, France
    J Hypertens 20:1973-80. 2002
    ..Stratification of population groups according to cardiovascular risk level is recommended for primary prevention...
  24. ncbi request reprint The correlation between isolated interventricular septal hypertrophy and 24-h ambulatory blood pressure monitoring in apparently healthy air crew
    David Harpaz
    Israel Air Force Aeromedical Centre, IDF, Tel Hashomer, Israel
    Blood Press Monit 7:225-9. 2002
    ..However, the natural history of isolated septal hypertrophy, identified by echocardiography in otherwise healthy subjects is not well defined...
  25. ncbi request reprint Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT)
    Giuseppe Mancia
    University of Milano Bicocca, St Gerardo Hospital, Monza, Milan, Italy
    Hypertension 41:431-6. 2003
    ..Our results suggest that nifedipine could be considered as first-line therapy for hypertensive diabetics...
  26. pmc Therapeutic actions of allylmercaptocaptopril and captopril in a rat model of metabolic syndrome
    Paul Ernsberger
    Department of Nutrition, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 4906, USA
    Am J Hypertens 20:866-74. 2007
    ..We sought to test the hypothesis that the conjugation of allicin to captopril may confer additional therapeutic actions in metabolic disease...
  27. ncbi request reprint A comparative crossover evaluation of amlodipine and nifedipine GITS before and after a missed dose: 48-h blood pressure profiles
    Naomi Nussinovitch
    Am J Hypertens 15:580-2. 2002
  28. ncbi request reprint Allylmercaptocaptopril: a new antihypertensive drug
    Talia Miron
    Weizmann Institute of Science, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Am J Hypertens 17:71-3. 2004
    ..CPSSA also decreased the high levels of triglycerides to normal. The new stable compound allylmercaptocaptopril combines the beneficial properties of captopril and allicin and is a potential candidate for antihypertensive drug therapy...
  29. ncbi request reprint Combination therapy as first-line treatment for hypertension
    Irene Gavras
    Hypertension and Atherosclerosis Section, Boston University School of Medicine, 715 Albany Street, W508, Boston, MA 02118, USA
    Curr Hypertens Rep 6:267-72. 2004
    ....
  30. ncbi request reprint Fructose-induced fatty liver disease: hepatic effects of blood pressure and plasma triglyceride reduction
    Zvi Ackerman
    Hebrew University Hadassah Medical Center, Jerusalem, Israel
    Hypertension 45:1012-8. 2005
    ..Drugs administered to treat various aspects of the metabolic syndrome could have hepatic effects. An increase in HIC in rats with NAFLD could be associated with increased hepatic fibrosis...
  31. ncbi request reprint 24-hour ambulatory blood pressure monitoring in children with familial dysautonomia
    Naomi Nussinovitch
    A J Chorley Institute for Hypertension, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Pediatr Nephrol 20:507-11. 2005
    ..The present study of 24-hour ambulatory blood pressure monitoring in children with familial dysautonomia was carried out to investigate the pattern of blood pressure in this syndrome...
  32. ncbi request reprint Clinical significance of renal function in hypertensive patients at high risk: results from the INSIGHT trial
    Peter W de Leeuw
    Department of Medicine, University Hospital Maastricht, Maastricht, The Netherlands
    Arch Intern Med 164:2459-64. 2004
    ..To assess this role of renal function in more detail, we studied the evolution of renal function and the relationship of renal function with mortality and morbidity in the Intervention as a Goal in Hypertension Treatment (INSIGHT) study...
  33. ncbi request reprint Trandolapril and endothelin antagonist LU-135252 in the treatment of the fructose-induced hypertensive, hyperinsulinemic, hypertriglyceridemic rat
    Orit Ezra-Nimni
    Chorley Institute for Hypertension Research, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Am J Hypertens 16:324-8. 2003
    ....
  34. ncbi request reprint Meeting the challenges of hypertension in sub-Saharan Africa
    Y K Seedat
    Cardiovasc J S Afr 17:47-8. 2006
  35. ncbi request reprint [Ambulatory blood pressure monitoring in diabetic hypertensive patients]
    Jenya Kruchkovich
    Department of Obstetrics and Gynecology, Barzilay Hospital, Ashkelon, Israel
    Harefuah 146:18-21, 79. 2007
    ..The 24 hour ABPM measurements should be recommended in all diabetic hypertensive patients in whom aggressive treatment covering nighttime should be offered...
  36. ncbi request reprint Effects of amlodipine, captopril, and bezafibrate on oxidative milieu in rats with fatty liver
    Zvi Ackerman
    Department of Medicine, Hadassah Hebrew University Medical Center, Mount Scopus Campus, Jerusalem 91240, Israel
    Dig Dis Sci 53:777-84. 2008
    ..Drugs administered to treat hypertension and hypertriglyceridemia could lead to a variety of changes in the hepatic oxidative, anti-oxidative milieu...