A Ravid

Summary

Affiliation: Tel Aviv University
Country: Israel

Publications

  1. ncbi request reprint Vitamin D enhances mitogenesis mediated by keratinocyte growth factor receptor in keratinocytes
    Anat Gamady
    The Basil and Gerald Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Petah Tikva, Israel
    J Cell Biochem 89:440-9. 2003
  2. ncbi request reprint Vitamin D inhibits the activation of stress-activated protein kinases by physiological and environmental stresses in keratinocytes
    A Ravid
    Basil and Gerald Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Beilinson Campus, Petah Tikva 49100, Israel
    J Endocrinol 173:525-32. 2002
  3. ncbi request reprint The role of reactive oxygen species in the anticancer activity of vitamin D
    Amiram Ravid
    Laboratory for Endocrine Immunology, Felsenstein Medical Research Center, Beilinson Campus, 49100 Petah Tikva, Israel
    Recent Results Cancer Res 164:357-67. 2003
  4. ncbi request reprint Programmed cell death of stressed keratinocytes and its inhibition by vitamin D: the role of death and survival signaling pathways
    T Diker-Cohen
    Basil and Gerald Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel
    Apoptosis 11:519-34. 2006
  5. doi request reprint Upregulation of MMP-9 production by TNFalpha in keratinocytes and its attenuation by vitamin D
    K Bahar-Shany
    Basil and Gerald Felsenstein Medical Research Center, Tel Aviv University, Tel Aviv, Israel
    J Cell Physiol 222:729-37. 2010
  6. ncbi request reprint Vitamin D is a prooxidant in breast cancer cells
    R Koren
    Basil and Gerald Felsenstein Medical Research Center, Rabin Medical Center, Petah Tikva, Israel
    Cancer Res 61:1439-44. 2001
  7. doi request reprint Vitamin D inhibits captopril-induced cell detachment and apoptosis in keratinocytes
    T Zeeli
    Department of Dermatology, Rabin Medical Center, Petah Tikva, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Br J Dermatol 164:62-7. 2011
  8. doi request reprint Vitamin D protects keratinocytes from deleterious effects of ionizing radiation
    M Langberg
    The Basil and Gerald Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Beilinson Campus, Rabin Medical Center, Petah Tikva 49100, Israel
    Br J Dermatol 160:151-61. 2009
  9. ncbi request reprint Vitamin D enhances caspase-dependent and independent TNF-induced breast cancer cell death: the role of reactive oxygen species
    G E Weitsman
    Felsenstein Medical Research Center, Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Ann N Y Acad Sci 1010:437-40. 2003
  10. ncbi request reprint Synergistic anticancer activity of 1,25-dihydroxyvitamin D(3) and immune cytokines: the involvement of reactive oxygen species
    R Koren
    Department of Physiology and Pahrmacology, The Basil and Gerald Felsenstein Medical Research Center, Rabin Medical Center, Petah Tikva, Israel
    J Steroid Biochem Mol Biol 73:105-12. 2000

Collaborators

  • M David
  • E Fenig
  • Ruth Koren
  • Gregory E Weitsman
  • Uri A Liberman
  • M Langberg
  • T Zeeli
  • K Bahar-Shany
  • C Rotem
  • Ester Ziv
  • Carmela Rotem
  • T Diker-Cohen
  • G E Weitsman
  • Talia Diker-Cohen
  • Anat Gamady
  • Mor Miodovnik
  • Efrat Zuck
  • U A Liberman
  • Dina Ron

Detail Information

Publications16

  1. ncbi request reprint Vitamin D enhances mitogenesis mediated by keratinocyte growth factor receptor in keratinocytes
    Anat Gamady
    The Basil and Gerald Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Petah Tikva, Israel
    J Cell Biochem 89:440-9. 2003
    ....
  2. ncbi request reprint Vitamin D inhibits the activation of stress-activated protein kinases by physiological and environmental stresses in keratinocytes
    A Ravid
    Basil and Gerald Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Beilinson Campus, Petah Tikva 49100, Israel
    J Endocrinol 173:525-32. 2002
    ....
  3. ncbi request reprint The role of reactive oxygen species in the anticancer activity of vitamin D
    Amiram Ravid
    Laboratory for Endocrine Immunology, Felsenstein Medical Research Center, Beilinson Campus, 49100 Petah Tikva, Israel
    Recent Results Cancer Res 164:357-67. 2003
    ....
  4. ncbi request reprint Programmed cell death of stressed keratinocytes and its inhibition by vitamin D: the role of death and survival signaling pathways
    T Diker-Cohen
    Basil and Gerald Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel
    Apoptosis 11:519-34. 2006
    ..Since mimicking this effect by pharmacological inhibition resulted in the attenuation of caspase activation, we infer that these pathways are involved in keratinocyte protection by 1,25(OH)2D3...
  5. doi request reprint Upregulation of MMP-9 production by TNFalpha in keratinocytes and its attenuation by vitamin D
    K Bahar-Shany
    Basil and Gerald Felsenstein Medical Research Center, Tel Aviv University, Tel Aviv, Israel
    J Cell Physiol 222:729-37. 2010
    ..By down-regulating MMP-9 levels active vitamin D derivatives may attenuate deleterious effects due to excessive TNFalpha-induced proteolytic activity associated with cutaneous inflammation...
  6. ncbi request reprint Vitamin D is a prooxidant in breast cancer cells
    R Koren
    Basil and Gerald Felsenstein Medical Research Center, Rabin Medical Center, Petah Tikva, Israel
    Cancer Res 61:1439-44. 2001
    ....
  7. doi request reprint Vitamin D inhibits captopril-induced cell detachment and apoptosis in keratinocytes
    T Zeeli
    Department of Dermatology, Rabin Medical Center, Petah Tikva, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Br J Dermatol 164:62-7. 2011
    ..This medication also triggers apoptosis in human keratinocytes. Calcitriol, the hormonally active vitamin D metabolite, protects keratinocytes from programmed cell death induced by various noxious stimuli...
  8. doi request reprint Vitamin D protects keratinocytes from deleterious effects of ionizing radiation
    M Langberg
    The Basil and Gerald Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Beilinson Campus, Rabin Medical Center, Petah Tikva 49100, Israel
    Br J Dermatol 160:151-61. 2009
    ..Calcitriol, the hormonally active vitamin D metabolite, protects keratinocytes from programmed cell death induced by various noxious stimuli...
  9. ncbi request reprint Vitamin D enhances caspase-dependent and independent TNF-induced breast cancer cell death: the role of reactive oxygen species
    G E Weitsman
    Felsenstein Medical Research Center, Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Ann N Y Acad Sci 1010:437-40. 2003
    ..We postulate that the interaction of TNF and calcitriol on the level of the mitochondria underlies the enhancement of TNF-induced, ROS-mediated caspase-dependent and -independent cell death...
  10. ncbi request reprint Synergistic anticancer activity of 1,25-dihydroxyvitamin D(3) and immune cytokines: the involvement of reactive oxygen species
    R Koren
    Department of Physiology and Pahrmacology, The Basil and Gerald Felsenstein Medical Research Center, Rabin Medical Center, Petah Tikva, Israel
    J Steroid Biochem Mol Biol 73:105-12. 2000
    ..We conclude that 1,25(OH)(2)D(3) can act synergistically with anticancer cytokines present in the tumor milieu and that ROS plays a mediatory role in this interaction...
  11. ncbi request reprint Vitamin D sensitizes breast cancer cells to the action of H2O2: mitochondria as a convergence point in the death pathway
    Gregory E Weitsman
    Basil and Gerald Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Beilinson Campus, Petah Tikva 49100, Israel
    Free Radic Biol Med 39:266-78. 2005
    ..These findings indicate that calcitriol sensitizes breast cancer cells to ROS-induced death by affecting event(s) common to both caspase-dependent and -independent modes of cell death upstream to mitochondrial damage...
  12. ncbi request reprint Vitamin D protects keratinocytes from apoptosis induced by osmotic shock, oxidative stress, and tumor necrosis factor
    Talia Diker-Cohen
    Department of Physiology and Pharmacology, Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Ann N Y Acad Sci 1010:350-3. 2003
    ..These results are in accordance with previous in vivo findings that vitamin D protects epidermal keratinocytes from apoptosis due to UV radiation or chemotherapy...
  13. ncbi request reprint Calcitriol sensitizes colon cancer cells to H2O2-induced cytotoxicity while inhibiting caspase activation
    Ruth Koren
    Basil and Gerald Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Rabin Medical Center, Beilinson Campus, Petah Tikva 49100, Israel
    J Steroid Biochem Mol Biol 101:151-60. 2006
    ..The sensitization of colon cancer cells to ROS-induced cytotoxicity may contribute to its assumed action as a chemopreventive agent and to its therapeutic potential alone or in combination with other anti-cancer modalities...
  14. ncbi request reprint Two modes of ERK activation by TNF in keratinocytes: different cellular outcomes and bi-directional modulation by vitamin D
    Ester Ziv
    The Basil and Gerald Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Cell Biochem 104:606-19. 2008
    ..It is possible that effects on the ERK cascade contribute to the effects of calcitriol and its synthetic analogs on cutaneous inflammation and keratinocyte proliferation...
  15. ncbi request reprint Vitamin D enhances caspase-dependent and -independent TNFalpha-induced breast cancer cell death: The role of reactive oxygen species and mitochondria
    Gregory E Weitsman
    Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Int J Cancer 106:178-86. 2003
    ..It is possible that the interaction of TNFalpha and calcitriol on the level of the mitochondria is the underlying mechanism responsible for the enhancement of TNFalpha-induced, ROS-mediated caspase-dependent and -independent cell death...
  16. ncbi request reprint The role of p38 MAP kinase in the synergistic cytotoxic action of calcitriol and TNF-alpha in human breast cancer cells
    Gregory E Weitsman
    Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Steroid Biochem Mol Biol 89:361-4. 2004
    ....