Moshe Phillip

Summary

Affiliation: Tel Aviv University
Country: Israel

Publications

  1. ncbi Use of insulin pump therapy in the pediatric age-group: consensus statement from the European Society for Paediatric Endocrinology, the Lawson Wilkins Pediatric Endocrine Society, and the International Society for Pediatric and Adolescent Diabetes, endors
    Moshe Phillip
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tikva, Israel
    Diabetes Care 30:1653-62. 2007
  2. ncbi Nocturnal glucose control with an artificial pancreas at a diabetes camp
    Moshe Phillip
    Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva, Israel
    N Engl J Med 368:824-33. 2013
  3. ncbi Testosterone stimulates growth of tibial epiphyseal growth plate and insulin-like growth factor-1 receptor abundance in hypophysectomized and castrated rats
    M Phillip
    The Felsenstein Medical Research Center, Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center, Petach Tikva, Israel
    Endocrine 16:1-6. 2001
  4. ncbi Precocious puberty: growth and genetics
    Moshe Phillip
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva, Israel
    Horm Res 64:56-61. 2005
  5. ncbi European multicentre study in children born small for gestational age with persistent short stature: comparison of continuous and discontinuous growth hormone treatment regimens
    Moshe Phillip
    Institute for Endocrinology and Diabetes, Schneider Children s Medical Center of Israel and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Horm Res 71:52-9. 2009
  6. ncbi Diabetes technology and the human factor
    A Liberman
    Schneider Children s Medical Center of Israel, Petah Tikva, Israel
    Int J Clin Pract 65:83-90. 2011
  7. ncbi Growth without growth hormone
    Moshe Phillip
    Institute for Endocrinology and Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva, Israel
    J Pediatr Endocrinol Metab 15:1267-72. 2002
  8. ncbi Glycemic patterns detected by continuous subcutaneous glucose sensing in children and adolescents with type 1 diabetes mellitus treated by multiple daily injections vs continuous subcutaneous insulin infusion
    Naomi Weintrob
    Institute for Endocrinology and Diabetes, National Center of Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva, Israel
    Arch Pediatr Adolesc Med 158:677-84. 2004
  9. ncbi Interrelationship of extent of precocious adrenarche in appropriate for gestational age girls with clinical outcome
    Tal Oron
    Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petach Tikva, Israel
    J Pediatr 160:308-13. 2012
  10. ncbi Natural history of idiopathic advanced bone age diagnosed in childhood: pattern of growth and puberty
    Liora Lazar
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva, Israel
    Horm Res Paediatr 75:49-55. 2011

Detail Information

Publications90

  1. ncbi Use of insulin pump therapy in the pediatric age-group: consensus statement from the European Society for Paediatric Endocrinology, the Lawson Wilkins Pediatric Endocrine Society, and the International Society for Pediatric and Adolescent Diabetes, endors
    Moshe Phillip
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tikva, Israel
    Diabetes Care 30:1653-62. 2007
  2. ncbi Nocturnal glucose control with an artificial pancreas at a diabetes camp
    Moshe Phillip
    Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva, Israel
    N Engl J Med 368:824-33. 2013
    ..Recent studies have shown that an artificial-pancreas system can improve glucose control and reduce nocturnal hypoglycemia. However, it is not known whether such results can be replicated in settings outside the hospital...
  3. ncbi Testosterone stimulates growth of tibial epiphyseal growth plate and insulin-like growth factor-1 receptor abundance in hypophysectomized and castrated rats
    M Phillip
    The Felsenstein Medical Research Center, Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center, Petach Tikva, Israel
    Endocrine 16:1-6. 2001
    ..However, testosterone increased in a dose-dependent manner the abundance of IGF-1 receptor EGP. We conclude that testosterone has a direct, local, GH-independent effect on the EGP growth and IGF-1 receptor abundance...
  4. ncbi Precocious puberty: growth and genetics
    Moshe Phillip
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva, Israel
    Horm Res 64:56-61. 2005
    ..Detection of these genes will provide a tool for identification of children at risk of developing CPP, enabling early intervention with the aim of preventing its distressing outcomes...
  5. ncbi European multicentre study in children born small for gestational age with persistent short stature: comparison of continuous and discontinuous growth hormone treatment regimens
    Moshe Phillip
    Institute for Endocrinology and Diabetes, Schneider Children s Medical Center of Israel and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Horm Res 71:52-9. 2009
    ..The most effective growth hormone (GH) treatment regimen for increasing height in short children born small for gestational age (SGA) has not been well defined...
  6. ncbi Diabetes technology and the human factor
    A Liberman
    Schneider Children s Medical Center of Israel, Petah Tikva, Israel
    Int J Clin Pract 65:83-90. 2011
    ....
  7. ncbi Growth without growth hormone
    Moshe Phillip
    Institute for Endocrinology and Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva, Israel
    J Pediatr Endocrinol Metab 15:1267-72. 2002
    ..Leptin, insulin, and sex hormones locally activate the IGF system in the epiphyseal growth plate (EGP). Other, undiscovered hormones and growth factors may harbor the ability to directly influence the growth processes in the EGP...
  8. ncbi Glycemic patterns detected by continuous subcutaneous glucose sensing in children and adolescents with type 1 diabetes mellitus treated by multiple daily injections vs continuous subcutaneous insulin infusion
    Naomi Weintrob
    Institute for Endocrinology and Diabetes, National Center of Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva, Israel
    Arch Pediatr Adolesc Med 158:677-84. 2004
    ..To compare glycemic patterns by mode of therapy in children with type 1 diabetes mellitus using the Continuous Glucose Monitoring System (CGMS)...
  9. ncbi Interrelationship of extent of precocious adrenarche in appropriate for gestational age girls with clinical outcome
    Tal Oron
    Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petach Tikva, Israel
    J Pediatr 160:308-13. 2012
    ..To assess the interrelationship between extent of adrenarche at presentation in girls with precocious adrenarche (PA) born appropriate for gestational age and their growth pattern, pubertal course and adult height...
  10. ncbi Natural history of idiopathic advanced bone age diagnosed in childhood: pattern of growth and puberty
    Liora Lazar
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva, Israel
    Horm Res Paediatr 75:49-55. 2011
    ..BA advancement due to endocrinopathies is associated with early puberty and compromised adult height (AHt), necessitating treatment. The natural history of idiopathic BA advancement is not well-established...
  11. ncbi Continuous subcutaneous insulin infusion versus multiple daily injections in adolescents with type I diabetes mellitus: a randomized open crossover trial
    Daniela Cohen
    Institute for Endocrinology and Diabetes, National Center of Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tiqva, Israel
    J Pediatr Endocrinol Metab 16:1047-50. 2003
  12. ncbi Endocrine effects of valproate in adolescent girls with epilepsy
    Liat de Vries
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Petah Tiqwa, Israel
    Epilepsia 48:470-7. 2007
    ..To investigate the effect of epilepsy and/or valproate (VPA) monotherapy on physical growth, weight gain, pubertal development, and hormonal status in adolescent girls with epilepsy...
  13. ncbi Coexistent autoimmunity in familial type 1 diabetes: increased susceptibility in sib-pairs?
    Yael Lebenthal
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel SCMCI, Petach Tikva, Israel
    Horm Res Paediatr 75:284-90. 2011
    ..Type 1 diabetes (T1D) patients are at risk for additional autoimmune diseases (AID). Objective: To compare the characteristics of associated autoimmunity among familial (parent-offspring and sib-pair) subgroups and sporadic T1D patients...
  14. ncbi Comparison of continuous subcutaneous insulin infusion and multiple daily injection regimens in children with type 1 diabetes: a randomized open crossover trial
    Naomi Weintrob
    Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Pediatrics 112:559-64. 2003
    ..To compare the efficacy and feasibility of continuous subcutaneous insulin infusion (CSII) with multiple daily insulin injections (MDI) in children with type 1 diabetes...
  15. ncbi A novel loss-of-function mutation in GPR54/KISS1R leads to hypogonadotropic hypogonadism in a highly consanguineous family
    Revital Nimri
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, 14 Kaplan Street, Petah Tikva 49202, Israel
    J Clin Endocrinol Metab 96:E536-45. 2011
    ..Recently loss-of-function mutations of the GPR54 have been implicated as a cause of isolated idiopathic hypogonadotropic hypogonadism (IHH)...
  16. ncbi Exercise with and without an insulin pump among children and adolescents with type 1 diabetes mellitus
    Gil Admon
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petach Tikva 49202, Israel
    Pediatrics 116:e348-55. 2005
    ..We recommend that the pump be removed or turned off during prolonged exercise and that blood glucose concentrations be monitored for several hours after exercise, regardless of the pump mode...
  17. ncbi Feasibility study of automated overnight closed-loop glucose control under MD-logic artificial pancreas in patients with type 1 diabetes: the DREAM Project
    Revital Nimri
    Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, The National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, 14 Kaplan St, Petah Tikva, Israel
    Diabetes Technol Ther 14:728-35. 2012
    ..This inpatient feasibility study is the first step towards implementing an overnight closed-loop MDLAP system at the patient's home...
  18. ncbi Patient perceptions of using the OmniPod system compared with conventional insulin pumps in young adults with type 1 diabetes
    Yael Lebenthal
    1 The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petach Tikva, Israel
    Diabetes Technol Ther 14:411-7. 2012
    ..The main outcome measures were treatment satisfaction (Diabetes Treatment Satisfaction Questionnaire), user evaluation (OmniPod System User Evaluation Questionnaire), and HbA1c levels...
  19. ncbi Natural history of thyroid function tests over 5 years in a large pediatric cohort
    Liora Lazar
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva 49202, Israel
    J Clin Endocrinol Metab 94:1678-82. 2009
    ..Because clinical manifestations of thyroid disorders are variable and subtle in children and adolescents, thyroid function tests are often repeated in patients with nonspecific symptoms...
  20. ncbi Differentiated thyroid carcinoma in pediatric patients: comparison of presentation and course between pre-pubertal children and adolescents
    Liora Lazar
    Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva, Israel
    J Pediatr 154:708-14. 2009
    ..To evaluate the clinical characteristics, course, and outcome of differentiated thyroid carcinoma (DTC) in pre-pubertal children compared with adolescents...
  21. ncbi Endocrine outcome in long-term survivors of childhood brain tumors
    Shlomit Shalitin
    The Jesse Z and Lea Shafer Institute of Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petach Tikva, Israel
    Horm Res Paediatr 76:113-22. 2011
    ..To evaluate the rates of endocrine abnormalities in survivors of childhood brain tumors and identify risk factors...
  22. ncbi Does the timing of insulin pump therapy initiation after type 1 diabetes onset have an impact on glycemic control?
    Shlomit Shalitin
    1 The Jesse Z and Lea Shafer Institute of Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel and Felsenstein Medical Research Center, Petach Tikva, Israel
    Diabetes Technol Ther 14:389-97. 2012
    ....
  23. ncbi Insulin pump therapy in youth with type 1 diabetes: a retrospective paired study
    Revital Nimri
    Institute for Endocrinology and Diabetes, National Center of Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tiqwa, Israel
    Pediatrics 117:2126-31. 2006
    ..This improvement is associated with a decrease in the rate of severe hypoglycemia in the absence of weight gain...
  24. ncbi Homozygous microdeletion of the POU1F1, CHMP2B, and VGLL3 genes in chromosome 3--a novel syndrome
    Galia Gat-Yablonski
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqwa, Israel
    Am J Med Genet A 155:2242-6. 2011
    ..The homozygous deletion of the CHMP2B gene, previously associated with frontotemporal dementia, may contribute to the intellectual disability observed in this patient...
  25. ncbi Influence of weight-loss diets with different macronutrient compositions on health-related quality of life in obese youth
    Michal Yackobovitch-Gavan
    Institute for Endocrinology and Diabetes, National Center of Childhood Diabetes, Schneider Children s Medical Center of Israel, 14 Kaplan Street, Petah Tikva, Israel
    Appetite 51:697-703. 2008
    ....
  26. ncbi Premature thelarche: age at presentation affects clinical course but not clinical characteristics or risk to progress to precocious puberty
    Liat de Vries
    Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqwa, Israel
    J Pediatr 156:466-71. 2010
    ..To determine whether age at premature thelarche (PT) onset affects the clinical characteristics, course, and risk of progression to precocious puberty (PP)...
  27. ncbi GnRH agonist treatment in girls with precocious puberty does not compromise post-pubertal uterine size
    Avi Ben Haroush
    Helen Schneider Hospital for Women, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel
    Hum Reprod 22:895-900. 2007
    ....
  28. ncbi Factors associated with increased risk of insulin pump discontinuation in pediatric patients with type 1 diabetes
    Liat de Vries
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva, Israel Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Pediatr Diabetes 12:506-12. 2011
    ..There are few reports on rates and predictors for pump discontinuation in the pediatric population...
  29. ncbi Why pumps? Continuous subcutaneous insulin infusion for children and adolescents with type 1 diabetes
    Naomi Weintrob
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva, Israel
    Isr Med Assoc J 6:271-5. 2004
    ..Therefore, we believe that both CSII and MDI should be made available to the diabetic team and the patients to better tailor therapy, improve satisfaction and decrease the fear of hypoglycemia...
  30. ncbi Growth pattern and final height after cessation of gonadotropin-suppressive therapy in girls with central sexual precocity
    Liora Lazar
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva 49202, Israel
    J Clin Endocrinol Metab 92:3483-9. 2007
    ..5 yr...
  31. ncbi Pubertal course of persistently short children born small for gestational age (SGA) compared with idiopathic short children born appropriate for gestational age (AGA)
    Liora Lazar
    Institute for Endocrinology and Diabetes, Schneider Children's Medical Center of Israel, Petah Tikva, Israel
    Eur J Endocrinol 149:425-32. 2003
    ..001). CONCLUSION: Children born SGA have a normal pubertal course with a distinct pubertal growth pattern. This pattern may represent an altered regulation of their growth modalities...
  32. ncbi MD-logic artificial pancreas system: a pilot study in adults with type 1 diabetes
    Eran Atlas
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, The National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva, Israel
    Diabetes Care 33:1072-6. 2010
    ..Blood glucose control using these methods is limited due to the complexity of the biological system. The aim of this study was to describe the principles and clinical performance of the novel MD-Logic Artificial Pancreas (MDLAP) System...
  33. ncbi The glucokinase mutation p.T206P is common among MODY patients of Jewish Ashkenazi descent
    Yael Gozlan
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petach Tikva, Israel
    Pediatr Diabetes 13:e14-21. 2012
    ..Given that both the Israeli-Arabic and the various Israeli-Jewish communities tend to maintain ethnic seclusion, we speculated that it would be possible to identify a relatively narrow spectrum of mutations in the Israeli population...
  34. ncbi Familial type 1 diabetes mellitus - gender distribution and age at onset of diabetes distinguish between parent-offspring and sib-pair subgroups
    Yael Lebenthal
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva 49202, Israel
    Pediatr Diabetes 11:403-11. 2010
    ..Familial type 1 diabetes mellitus (T1D) comprises parent-offspring and sib-pair subgroups...
  35. ncbi Closing the loop: combining insulin pumps and glucose sensors in children with type 1 diabetes mellitus
    Shlomit Shalitin
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petach Tikva, Israel
    Pediatr Diabetes 7:45-9. 2006
    ..This review focuses on the steps towards closing the loop in the attempts to develop an artificial pancreas and on recent ongoing research and future directions in this field...
  36. ncbi Growth without growth hormone: growth pattern and final height of five patients with idiopathic combined pituitary hormone deficiency
    Liora Lazar
    Institute for Endocrinology and Diabetes, Schneider Children's Medical Center of Israel, Petah Tikva and Faculty of Medicine, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
    Clin Endocrinol (Oxf) 59:82-8. 2003
    ..As this was not mediated by GH, IGF-I, insulin or prolactin, some other growth factors probably played a growth-promoting role...
  37. ncbi Familial central precocious puberty suggests autosomal dominant inheritance
    Liat de Vries
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva, Israel
    J Clin Endocrinol Metab 89:1794-800. 2004
    ..58 (0.65 after exclusion of young siblings) assuming complete ascertainment. These results suggest autosomal dominant transmission with incomplete, sex-dependent penetrance...
  38. ncbi Childhood obesity complicating the differential diagnosis of maturity-onset diabetes of the young and type 2 diabetes
    Naomi Weintrob
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva, Israel
    Pediatr Diabetes 9:60-4. 2008
    ..To describe a proband with features of type 2 diabetes who was found to have concomitant maturity-onset diabetes of the young (MODY) and the consequent multigeneration genetic analysis...
  39. ncbi The influence of diet and/or exercise and parental compliance on health-related quality of life in obese children
    Michal Yackobovitch-Gavan
    Institute for Endocrinology and Diabetes, National Center of Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva, Israel
    Nutr Res 29:397-404. 2009
    ..Parental compliance is an important factor and may be assessed by the parents' cooperativeness in completing questionnaires...
  40. ncbi Leptin and regulation of linear growth
    Galia Gat-Yablonski
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Israel
    Curr Opin Clin Nutr Metab Care 11:303-8. 2008
    ..It was later found to be a pleiotropic hormone involved in the regulation of a variety of physiological processes. This review summarizes our recent understanding of the role of leptin as a linear growth-stimulating factor...
  41. ncbi Hypoglycemia in type 1 diabetes: a still unresolved problem in the era of insulin analogs and pump therapy
    Shlomit Shalitin
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, 14 Kaplan St, Petach Tikva 49202, Israel
    Diabetes Care 31:S121-4. 2008
    ....
  42. ncbi A novel loss-of-function mutation in OTX2 in a patient with anophthalmia and isolated growth hormone deficiency
    Liat Ashkenazi-Hoffnung
    The Jesse Z and Sara Lea Shafer Institute of Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, 14 Kaplan Street, 49202 Petach Tikva, Israel
    Hum Genet 127:721-9. 2010
    ....
  43. ncbi Relationship between changes in thyroid hormone level and severity of the postoperative course in neonates undergoing open-heart surgery
    Ovadia Dagan
    Pediatric Cardiac Intensive Care Unit, Schneider Children s Medical Center of Israel, Petah Tiqwa, Israel
    Paediatr Anaesth 16:538-42. 2006
    ..Our aim was to determine whether the changes in thyroid function after open-heart surgery in neonates depend on the postoperative course...
  44. ncbi Nutrition and bone growth in pediatrics
    Galia Gat-Yablonski
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, 14 Kaplan Street, Petah Tikva 49202, Israel
    Pediatr Clin North Am 58:1117-40, ix. 2011
    ..In addition we describe the effect of local regulators and nutritional factors on the growth process and suggest the involvement of new regulatory factors in the translation of nutrition to growth...
  45. ncbi Serum ferritin level as a predictor of impaired growth and puberty in thalassemia major patients
    Shlomit Shalitin
    Institute for Endocrinology and Diabetes, Schneider Children's Medical Center of Israel, Petah Tikva, Israel
    Eur J Haematol 74:93-100. 2005
    ..It remains to be determined whether improving chelation by earlier initiation of DFO or by the combined use of DFO and deferiprone will lead to better growth and sexual development without DFO toxicity...
  46. ncbi Continuous glucose monitoring for the evaluation of gravid women with type 1 diabetes mellitus
    Yariv Yogev
    Department of Obstetrics and Gynecology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel
    Obstet Gynecol 101:633-8. 2003
    ..To compare the daily glycemic profile reflected by continuous and intermittent blood glucose monitoring in pregnant women with type 1 diabetes and to compare the treatment protocols based on the two monitoring methods...
  47. ncbi Growth and metabolic control in patients with type 1 diabetes and celiac disease: a longitudinal observational case-control study
    Irit Taler
    Department of Pediatrics B, Schneider Children s Medical Center of Israel, Petach Tikva, Israel
    Pediatr Diabetes 13:597-606. 2012
    ..The occurrence of celiac disease (CD) in patients with type 1 diabetes (T1D) is increasing...
  48. ncbi Retrospective comparative analysis of metabolic control and early complications in familial and sporadic type 1 diabetes patients
    Yael Lebenthal
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel SCMCI, Petach Tikva 49202
    J Diabetes Complications 26:219-24. 2012
    ..Genetic susceptibility and lifestyle are associated with glycemic control and diabetic complications in type 1 diabetes (T1D)...
  49. ncbi Modulation of brain insulin-like growth factor I (IGF-I) binding sites and hypothalamic GHRH and somatostatin levels by exogenous growth hormone and IGF-I in juvenile rats
    Rina Eshet
    Laboratory of Endocrinology and Diabetes, Felsenstein Medical Research Center, Petah Tikva, Israel
    J Mol Neurosci 22:179-88. 2004
    ..Because IGF-I is a potent neurotrophic agent, this effect may have important implications for states of neurodegenerative diseases...
  50. ncbi Children born small for gestational age: growth patterns, growth hormone treatment and long-term sequelae
    Shlomit Shalitin
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center, Petah Tikqa, Israel
    Isr Med Assoc J 5:877-82. 2003
  51. ncbi Role of parenting style in achieving metabolic control in adolescents with type 1 diabetes
    Maayan Shorer
    National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petach Tikva, Israel
    Diabetes Care 34:1735-7. 2011
    ..To examine the role of parenting style in achieving metabolic control and treatment adherence in adolescents with type 1 diabetes...
  52. ncbi Automatic learning algorithm for the MD-logic artificial pancreas system
    Shahar Miller
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, The National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva, Israel
    Diabetes Technol Ther 13:983-90. 2011
    ....
  53. ncbi Children diagnosed with diabetes during infancy have unique clinical characteristics
    Revital Nimri
    Institute of Endocrinology and Diabetes, National Center of Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqwa, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Horm Res 67:263-7. 2007
    ..Characterizing clinical and biochemical features of children diagnosed with diabetes mellitus between the ages of 6-24 months...
  54. ncbi Weight gain associated with increased food intake and low habitual activity levels in male adolescent schizophrenic inpatients treated with olanzapine
    Doron Gothelf
    Behavioral Genetic Clinic, Richard E Feinberg Department of Psychiatry, Schneider Children s Medical Center of Israel, Petah Tiqwa
    Am J Psychiatry 159:1055-7. 2002
    ..The authors studied weight gain mechanisms and energy balance in patients treated with olanzapine...
  55. ncbi Stress hyperglycemia: a sign of familial diabetes in children
    Tal Oron
    National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petach Tikva, Israel
    Pediatrics 128:e1614-7. 2011
    ..697T→C p.C233R in the first case and c.616A→C p.T206P in the second case. Our findings suggest that stress hyperglycemia during early childhood in association with a positive family history of DM might be a sign of monogenic diabetes...
  56. ncbi Craniopharyngioma presenting as precocious puberty and accelerated growth
    Liat de Vries
    Institute of Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tiqva, Israel
    Clin Pediatr (Phila) 42:181-4. 2003
  57. ncbi Nutrition and bone growth in pediatrics
    Galia Gat-Yablonski
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, 14 Kaplan Street, Petah Tikva 49202, Israel
    Endocrinol Metab Clin North Am 38:565-86. 2009
    ..In addition we describe the effect of local regulators and nutritional factors on the growth process and suggest the involvement of new regulatory factors in the translation of nutrition to growth...
  58. ncbi Ultrasonographic and clinical parameters for early differentiation between precocious puberty and premature thelarche
    Liat de Vries
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Israel
    Eur J Endocrinol 154:891-8. 2006
    ....
  59. ncbi Nutritional biomarkers for growth outcomes: perspective of the endocrinologist
    Michal Yackobovitch-Gavan
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Children s Diabetes, Schneider Children s Medical Center of Israel, Tel Aviv, Israel
    World Rev Nutr Diet 106:19-25. 2013
    ..This paper will discuss the following questions: What is a good nutritional biomarker for growth outcomes? Which nutritional biomarkers are already known? What additional biomarkers does the endocrinologist need?..
  60. ncbi Spontaneous normalization of anti-tissue transglutaminase antibody levels is common in children with type 1 diabetes mellitus
    Orith Waisbourd-Zinman
    Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children s Medical Center of Israel, 14 Kaplan Street, 49202 Petach Tikva, Israel
    Dig Dis Sci 57:1314-20. 2012
    ..The prevalence of celiac disease among type 1 diabetes mellitus (T1DM) patients is 5-10 times higher than in the general population. Thus, evaluation of celiac serology is indicated at diagnosis of T1DM and on follow up...
  61. ncbi Maturity onset diabetes of the young--review
    Galia Gat-Yablonski
    Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tikva
    Pediatr Endocrinol Rev 3:514-20. 2006
    ..The genetic findings have important clinical implications, allowing for proper genetic counseling, early diagnosis, and better care of patients...
  62. ncbi Pelvic ultrasound examination in girls with precocious puberty is a useful adjunct in gonadotrophin-releasing hormone analogue therapy monitoring
    Liat de Vries
    The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqwa, Israel
    Clin Endocrinol (Oxf) 75:372-7. 2011
    ..As there are no standard criteria for monitoring suppression during treatment of central precocious puberty (CPP) with gonadotrophin-releasing hormone analogues (GnRHa), we assessed the use of pelvic ultrasound examination for this purpose...
  63. ncbi Decreased cortisol secretion in nonclassical 21-hydroxylase deficiency before and during glucocorticoid therapy
    Naomi Weintrob
    Institute of Endocrinology and Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva
    J Pediatr Endocrinol Metab 15:985-91. 2002
    ..The cortisol response in patients with nonclassical 21-hydroxylase deficiency (NC21OHD) was assessed before and during hydrocortisone therapy and the findings were related to genotype...
  64. ncbi Use of GnRH agonist and human chorionic gonadotrophin tests for differentiating constitutional delayed puberty from gonadotrophin deficiency in boys
    Arieh Kauschansky
    Institute of Endocrinology and Diabetes, Schneider Children's Medical Center of Israel, 14 Kaplan Street, Petah Tikva 49202, Israel
    Clin Endocrinol (Oxf) 56:603-7. 2002
    ..0-3.0 ml, P < 0.0001), which remained unchanged on re-examination 3.0 +/- 0.5 years later. CONCLUSIONS: The GnRH-agonist test and the repeated-injection hCG test are reliable diagnostic tools for differentiating CDP from GD in boys...
  65. ncbi [Diabetic ketoacidosis in children and adolescents]
    Naomi Weintrob
    The Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv
    Harefuah 146:945-51, 997-8. 2007
    ..The aim of this survey is to present guidelines for the treatment of diabetic ketoacidosis (DKA) in children and to recommend preventive measures...
  66. ncbi Bedside scoring procedure for the diagnosis of diabetic peripheral neuropathy in young patients with type 1 diabetes mellitus
    Shlomit Shalitin
    Institute for Endocrinology and Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva
    J Pediatr Endocrinol Metab 15:613-20. 2002
    ..The prevalence of DPN was estimated and its risk factors identified...
  67. ncbi Leptin regulates chondrogenic differentiation in ATDC5 cell-line through JAK/STAT and MAPK pathways
    Miri Ben-Eliezer
    Felsenstein Medical Research Center, 14 Kaplan Street, Petach Tikva, 49202, Israel
    Endocrine 32:235-44. 2007
    ..This is the first demonstration that these pathways are involved in leptin-induced growth...
  68. ncbi Autoimmune thyroiditis in infants with Down's syndrome
    Shlomit Shalitin
    Institute of Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children s Medical Center of Israel, Petah Tiqva
    J Pediatr Endocrinol Metab 15:649-52. 2002
    ..We suggest that follow-up of thyroid function and thyroid autoantibodies should be started from infancy in Down's syndrome to prevent further deterioration of mental development and growth...
  69. ncbi The first meeting of the Loop Club
    Tadej Battelino
    University Children 's Hospital, Department of Pediatric and Adolescent Endocrinology, Ljubljana, Slovenia
    J Pediatr Endocrinol Metab 17:375-6. 2004
  70. ncbi Weight gain associated with olanzapine and risperidone in adolescent patients: a comparative prospective study
    Gidi Ratzoni
    Adolescent Inpatient Unit, Shalvata Mental Health Center, Hod Hasharon, Israel
    J Am Acad Child Adolesc Psychiatry 41:337-43. 2002
    ..This side effect should be taken into consideration before prescribing these medications, especially in patients at high risk...
  71. ncbi Endocrine regulation of the growth plate
    Ola Nilsson
    Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 1862, USA
    Horm Res 64:157-65. 2005
    ..This review provides an overview of the endocrine signals that regulate longitudinal bone growth, their interactions, and the mechanisms by which they affect growth plate chondrogenesis...
  72. ncbi The Fifth European Growth Plate Working Group Symposium. 21st September 2005, Lyon, France
    Helen Kalirai
    Department of Clinical Research, Christie Hospital NHS Trust, Manchester, UK
    J Pediatr Endocrinol Metab 19:183-90. 2006
    ....
  73. ncbi Transdermal delivery of human growth hormone through RF-microchannels
    Galit Levin
    TransPharma Medical, Lod 71291, Israel
    Pharm Res 22:550-5. 2005
    ..To evaluate the bioavailability and bioactivity of human growth hormone (hGH) delivered transdermally through microchannels (MCs) in the skin created by radio-frequency (RF) ablation...
  74. ncbi The Sixth ESPE Growth Plate Working Group Symposium (EUROGROP), June 30th, Rotterdam, the Netherlands, "a multidisciplinary approach to growth plate biology"
    Joyce Emons
    Department of Paediatrics, Leiden University Medical Center, Leiden, The Netherlands
    Pediatr Endocrinol Rev 4:153-9. 2006
  75. ncbi Children referred for signs of early puberty warrant endocrine evaluation and follow-up
    Liat de Vries
    J Clin Endocrinol Metab 90:593; author reply 593-4. 2005
  76. ncbi The 4th European Growth Plate Working Group Symposium (EUROGROP). 10th September 2004, Basel, Switzerland
    Andrei Chagin
    Pediatric Endocrinology Unit, Karolinska Institutet, Stockholm, Sweden
    J Pediatr Endocrinol Metab 18:823-7. 2005
  77. ncbi Leptin acts as a growth factor on the chondrocytes of skeletal growth centers
    Gila Maor
    Department of Morphology Science, Rappaport Faculty of Medicine, Technion, Haifa, Israel
    J Bone Miner Res 17:1034-43. 2002
    ..Some of its effects on the growing bone may be mediated by the IGF system via regulation of IGF-I receptor expression. We speculate that the high circulating levels of leptin in obese children might contribute to their growth...
  78. ncbi Initiation of insulin glargine therapy in type 2 diabetes subjects suboptimally controlled on oral antidiabetic agents: results from the AT.LANTUS trial
    M Davies
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 10:387-99. 2008
    ..This subgroup analysis investigated the initiation of once-daily glargine therapy in patients suboptimally controlled on multiple OADs...
  79. ncbi A cross-sectional international survey of continuous subcutaneous insulin infusion in 377 children and adolescents with type 1 diabetes mellitus from 10 countries
    Thomas Danne
    Kinderkrankenhaus auf der Bult, Hannover, Germany
    Pediatr Diabetes 6:193-8. 2005
    ....
  80. ncbi Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials
    Nish Chaturvedi
    International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College Healthcare NHS Trust, London, UK
    Lancet 372:1394-402. 2008
    ..We therefore designed the DIabetic REtinopathy Candesartan Trials (DIRECT) Programme to assess whether candesartan could reduce the incidence and progression of retinopathy in type 1 diabetes...
  81. ncbi Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled trial
    Anne Katrin Sjølie
    Department of Ophthalmology, Odense University Hospital, Odense, Denmark
    Lancet 372:1385-93. 2008
    ..Diabetic retinopathy remains a leading cause of visual loss in people of working age. We examined whether candesartan treatment could slow the progression and, secondly, induce regression of retinopathy in people with type 2 diabetes...
  82. ncbi Insulin pump therapy for 1-6 year old children with type 1 diabetes
    Naim Shehadeh
    Pediatric Diabetes Unit, Meyer Children s Hospital of Haifa, Haifa, Israel
    Isr Med Assoc J 6:284-6. 2004
    ..The management of diabetes in preschool children poses unique difficulties for both the families and the medical team...
  83. ncbi Growth retardation in pediatric Crohn's disease: pathogenesis and interventions
    Raanan Shamir
    Pediatric Gastroenterology Division of the Meyer Children s Hospital, Haifa
    Inflamm Bowel Dis 13:620-8. 2007
    ..This review summarizes current knowledge as well as gaps in our understanding of the mechanisms involved and the usefulness of the different treatment modalities in promoting growth in CD patients...
  84. ncbi Growth hormone (GH) hypersecretion and GH receptor resistance in streptozotocin diabetic mice in response to a GH secretagogue
    Peter B Johansen
    Pharmacological Research 3, Novo Nordisk A S, Måløv, Denmark
    Exp Diabesity Res 4:73-81. 2003
    ..Accordingly, it is proposed that STZ diabetic mice may be a better model of the perturbations of the GH/IGF-I axis in diabetes than STZ diabetic rats...
  85. ncbi The Third European Growth Plate Working Group Symposium. 17th September 2003, Ljubljana, Slovenia
    Helen Robson
    Department of Clinical Research, Christie Hospital NHS Trust, Manchester, UK
    J Pediatr Endocrinol Metab 17:685-94. 2004
  86. ncbi Improved glycemic control in poorly controlled patients with type 1 diabetes using real-time continuous glucose monitoring
    Dorothee Deiss
    Children's Hospital Charit, Humboldt-University, Berlin, Germany
    Diabetes Care 29:2730-2. 2006
  87. ncbi Comparison between somatostatin analogues and ACE inhibitor in the NOD mouse model of diabetic kidney disease
    Yael Segev
    Department of Micrbiology and Immunology, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Nephrol Dial Transplant 19:3021-8. 2004
    ..Enalapril treatment had no effect on renal hypertrophy and did not cause a significant decrease in mesangial type IV collagen deposition. A synergistic effect of combined SST-ACEi therapy could not be shown in this study...
  88. ncbi The Second European Growth Plate Working Group Symposium 25th September 2002, Madrid, Spain
    Helen Robson
    Department of Clinical Research, Christie Hospital NHS Trust, Manchester, UK
    J Pediatr Endocrinol Metab 16:461-6. 2003
  89. ncbi The effect of growth hormone on the development of diabetic kidney disease in rats
    Daniel Landau
    Department of Pediatrics, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel
    Nephrol Dial Transplant 18:694-702. 2003
    ..Nephropathy is the most severe complication of diabetes mellitus. We investigated the effect of exogenous growth hormone (GH) administration on renal function and matrix deposition in the streptozotocin (STZ) model of type I-diabetic rat...
  90. ncbi Meeting Report:The 7th ESPE Growth Plate Working Group Symposium - EUROGROP June 27th 2007, Helsinki, Finland
    Razvan L Miclea
    Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands
    Pediatr Endocrinol Rev 5:680-5. 2007
    ....