Livnat Jerby

Summary

Affiliation: Tel Aviv University
Country: Israel

Publications

  1. ncbi request reprint Predicting cancer-specific vulnerability via data-driven detection of synthetic lethality
    Livnat Jerby-Arnon
    The Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv 6997801, Israel Electronic address
    Cell 158:1199-209. 2014
  2. ncbi request reprint Predicting drug targets and biomarkers of cancer via genome-scale metabolic modeling
    Livnat Jerby
    The Blavatnik School of Computer Science, Tel Aviv University, Israel
    Clin Cancer Res 18:5572-84. 2012
  3. pmc Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism
    Livnat Jerby
    The Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, Israel
    Mol Syst Biol 6:401. 2010
  4. pmc Predicting selective drug targets in cancer through metabolic networks
    Ori Folger
    The Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, Israel
    Mol Syst Biol 7:501. 2011
  5. ncbi request reprint Metabolic associations of reduced proliferation and oxidative stress in advanced breast cancer
    Livnat Jerby
    The Blavatnik School of Computer Science, The Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cancer Res 72:5712-20. 2012

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Predicting cancer-specific vulnerability via data-driven detection of synthetic lethality
    Livnat Jerby-Arnon
    The Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv 6997801, Israel Electronic address
    Cell 158:1199-209. 2014
    ..Finally, we identify synthetic lethality arising from gene overactivation and use it to predict drug efficacy. These results form a computational basis for exploiting synthetic lethality to uncover cancer-specific susceptibilities. ..
  2. ncbi request reprint Predicting drug targets and biomarkers of cancer via genome-scale metabolic modeling
    Livnat Jerby
    The Blavatnik School of Computer Science, Tel Aviv University, Israel
    Clin Cancer Res 18:5572-84. 2012
    ..We then describe the initial steps made using it to study cancer metabolism and how it may be harnessed to enhance ongoing experimental efforts to identify drug targets and biomarkers for cancer in a rationale-based manner...
  3. pmc Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism
    Livnat Jerby
    The Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, Israel
    Mol Syst Biol 6:401. 2010
    ..67 versus 0.59). The approach presented can be used to construct other human tissue-specific models, and be applied to other organisms...
  4. pmc Predicting selective drug targets in cancer through metabolic networks
    Ori Folger
    The Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, Israel
    Mol Syst Biol 7:501. 2011
    ..Finally, potential selective treatments for specific cancers that depend on cancer type-specific downregulation of gene expression and somatic mutations are compiled...
  5. ncbi request reprint Metabolic associations of reduced proliferation and oxidative stress in advanced breast cancer
    Livnat Jerby
    The Blavatnik School of Computer Science, The Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cancer Res 72:5712-20. 2012
    ..Together, our findings greatly extend insights into core metabolic aberrations and their impact in breast cancer...