Research Topics
Genomes and GenesSpecies | Fuad A IraqiSummaryAffiliation: Tel Aviv University Country: Israel Publications
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Detail Information
Publications
The Collaborative Cross, developing a resource for mammalian systems genetics: a status report of the Wellcome Trust cohortFuad A Iraqi
Department of Human Microbiology, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel
Mamm Genome 19:379-81. 2008..The CC mice will be available for distribution free of any intellectual property constraints to serve as a community resource for systems genetics studies...
High resolution mapping of trypanosomosis resistance loci Tir2 and Tir3 using F12 advanced intercross lines with major locus Tir1 fixed for the susceptible alleleJoseph K Nganga
International Livestock Research Institute, PO Box 30709, Nairobi, Kenya
BMC Genomics 11:394. 2010..Tir1 represents the major trypanotolerance QTL...
Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant miceNicolas F Delahaye
Laboratoire de Pharmacogénétique des maladies parasitaires EA864, Universite de la Mediterranee, IFR48, Marseille, France
BMC Genomics 8:452. 2007..We investigated mouse transcriptional responses at early and late stages of infection by use of cDNA microarrays...
Mapping of chromosomal regions influencing immunological responses to gastrointestinal nematode infections in miceDavid M Menge
International Livestock Research Institute, PO Box 30709, Nairobi, Kenya
Parasite Immunol 25:341-9. 2003..Some of these QTL map to regions known to harbour genes responsible for the induction of immunological responses to intestinal worms...
Confirmation and dissection of QTL controlling resistance to malaria in miceMaria Hernandez Valladares
International Livestock Research Institute, Nairobi, Kenya
Mamm Genome 15:390-8. 2004..Each of the previously mapped QTL on Chrs 5 and 17 resolved into two linked QTLs. The distal and proximal QTLs on Chrs 5 and 17, respectively, map to the previously reported QTL...
Gene-knockout mice in malaria research: useful or misleading?Maria Hernandez-Valladares
International Livestock Research Institute, Naivasha Road, Nairobi, Kenya
Trends Parasitol 23:522-6. 2007..These mice have helped to indicate new resistance genes against human malaria and have provided valuable information about mechanisms of malaria resistance in mice...
Genetic resistance to malaria in mouse modelsMaria Hernandez-Valladares
International Livestock Research Institute, Naivasha Road, PO Box 30709, Nairobi 00100, Kenya
Trends Parasitol 21:352-5. 2005..In the future, the use of murine models for genetic resistance to malaria could lead to the identification of relevant genetic factors that control this devastating disease...
Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human Chromosome 5q31-q33Maria Hernandez-Valladares
International Livestock Research Institute ILRI, P O Box 30709, 00100, Nairobi, Kenya
Immunogenetics 56:115-7. 2004..Strikingly, several Th2 cytokines that are located within char8 have been identified to play a predominant role in the late stages of the infection...
Chromosomal regions controlling resistance to gastro-intestinal nematode infections in miceFuad A Iraqi
International Livestock Research Institute, PO Box 30709, Nairobi, Kenya
Mamm Genome 14:184-91. 2003..These may include breeding of resistant or tolerant livestock, development of vaccines, or identification of new anthelmintic drugs...
Genotype is a stronger determinant than sex of the mouse gut microbiotaAmir Kovacs
Department of Molecular Microbiology and Biotechnology, George S Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel
Microb Ecol 61:423-8. 2011..These findings imply that genetic polymorphisms help shape the intestinal microbiota of mammals and consequently could affect host susceptibility to diseases...
