E Z Fisman

Summary

Affiliation: Tel Aviv University
Country: Israel

Publications

  1. doi request reprint The metabolic syndrome entanglement: Cutting the Gordian knot
    Enrique Z Fisman
    Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Cardiovascular Diabetology Research Foundation, Holon, Israel
    Cardiol J 21:1-5. 2014
  2. doi request reprint Coronary calcium in patients with and without diabetes: first manifestation of acute or chronic coronary events is characterized by different calcification patterns
    Joseph Shemesh
    Sackler Faculty of Medicine, Tel Aviv University, 69978 Tel Aviv, Israel
    Cardiovasc Diabetol 12:161. 2013
  3. pmc Balanced pan-PPAR activator bezafibrate in combination with statin: comprehensive lipids control and diabetes prevention?
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Sheba Medical Center, 52621 Tel Hashomer, Israel
    Cardiovasc Diabetol 11:140. 2012
  4. pmc Fibrates are an essential part of modern anti-dyslipidemic arsenal: spotlight on atherogenic dyslipidemia and residual risk reduction
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Sheba Medical Center, Tel Hashomer, Israel
    Cardiovasc Diabetol 11:125. 2012
  5. pmc Effects of a vildagliptin/metformin combination on markers of atherosclerosis, thrombosis, and inflammation in diabetic patients with coronary artery disease
    Robert Klempfner
    Cardiac Rehabilitation Institute, Leviev Heart Center, Sheba Medical Center, 52621, Tel Hashomer, Israel
    Cardiovasc Diabetol 11:60. 2012
  6. pmc "The metabolic syndrome... is dead": these reports are an exaggeration
    Alexander Tenenbaum
    Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cardiovasc Diabetol 10:11. 2011
  7. pmc Statins research unfinished saga: desirability versus feasibility
    Enrique Z Fisman
    Cardiovasc Diabetol 4:8. 2005
  8. pmc "If it ain't broke, don't fix it": a commentary on the positive-negative results of the ACCORD Lipid study
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Sheba Medical Center, Tel Hashomer, Israel
    Cardiovasc Diabetol 9:24. 2010
  9. pmc Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Sheba Medical Center, 52621 Tel Hashomer, Israel
    Cardiovasc Diabetol 4:14. 2005
  10. pmc Does the lipid-lowering peroxisome proliferator-activated receptors ligand bezafibrate prevent colon cancer in patients with coronary artery disease?
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cardiovasc Diabetol 7:18. 2008

Collaborators

Detail Information

Publications83

  1. doi request reprint The metabolic syndrome entanglement: Cutting the Gordian knot
    Enrique Z Fisman
    Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Cardiovascular Diabetology Research Foundation, Holon, Israel
    Cardiol J 21:1-5. 2014
    ..Therefore, currently available evidences strongly support the concept of the MS as a critical clustering of CV risk factors and diabetes, representing a true and solid evolving clinical entity. ..
  2. doi request reprint Coronary calcium in patients with and without diabetes: first manifestation of acute or chronic coronary events is characterized by different calcification patterns
    Joseph Shemesh
    Sackler Faculty of Medicine, Tel Aviv University, 69978 Tel Aviv, Israel
    Cardiovasc Diabetol 12:161. 2013
    ..Aiming to elucidate these controversies we investigated the long-term outcome of coronary artery disease (CAD) in relation to degree of CAC in patients with and without DM from our annual cheek-up outpatient clinic...
  3. pmc Balanced pan-PPAR activator bezafibrate in combination with statin: comprehensive lipids control and diabetes prevention?
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Sheba Medical Center, 52621 Tel Hashomer, Israel
    Cardiovasc Diabetol 11:140. 2012
    ....
  4. pmc Fibrates are an essential part of modern anti-dyslipidemic arsenal: spotlight on atherogenic dyslipidemia and residual risk reduction
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Sheba Medical Center, Tel Hashomer, Israel
    Cardiovasc Diabetol 11:125. 2012
    ..Fibrates currently constitute an indispensable part of the modern anti-dyslipidemic arsenal for patients with atherogenic dyslipidemia...
  5. pmc Effects of a vildagliptin/metformin combination on markers of atherosclerosis, thrombosis, and inflammation in diabetic patients with coronary artery disease
    Robert Klempfner
    Cardiac Rehabilitation Institute, Leviev Heart Center, Sheba Medical Center, 52621, Tel Hashomer, Israel
    Cardiovasc Diabetol 11:60. 2012
    ..Animal evidence indicates that dipeptidyl peptidase-4 inhibitors have anti-atherosclerotic effects, yet clinical data are scarcely available...
  6. pmc "The metabolic syndrome... is dead": these reports are an exaggeration
    Alexander Tenenbaum
    Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cardiovasc Diabetol 10:11. 2011
    ..A third step should probably be kept for bariatric surgery...
  7. pmc Statins research unfinished saga: desirability versus feasibility
    Enrique Z Fisman
    Cardiovasc Diabetol 4:8. 2005
    ..In any case, conclusions based on surrogate endpoints cannot completely substitute head-to-head comparisons regarding patients' outcome...
  8. pmc "If it ain't broke, don't fix it": a commentary on the positive-negative results of the ACCORD Lipid study
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Sheba Medical Center, Tel Hashomer, Israel
    Cardiovasc Diabetol 9:24. 2010
    ..In patients without dyslipidemia this favorable effect - as expected - was absent...
  9. pmc Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Sheba Medical Center, 52621 Tel Hashomer, Israel
    Cardiovasc Diabetol 4:14. 2005
    ..More powerful new compounds with pan-PPAR activity and proven long-term safety should be highly effective in a clinical setting of patients with coexisting relevant lipid and glucose metabolism disorders...
  10. pmc Does the lipid-lowering peroxisome proliferator-activated receptors ligand bezafibrate prevent colon cancer in patients with coronary artery disease?
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cardiovasc Diabetol 7:18. 2008
    ..Therefore, we proposed to investigate a possible preventive effect of bezafibrate on the development of colon cancer in patients with coronary artery disease during a 6-year follow-up...
  11. pmc Long-term effects of peroxisome proliferator-activated receptor ligand bezafibrate on N-terminal pro-B type natriuretic peptide in patients with advanced functional capacity impairment
    Koichi Node
    Department of Cardiovascular and Renal Medicine, Saga University Faculty of Medicine, Saga, Japan
    Cardiovasc Diabetol 8:5. 2009
    ..The current study aimed to investigate the long-term effects of bezafibrate on ProBNP level in patients with pre-existing CAD and advanced functional capacity impairment...
  12. pmc Atherogenic dyslipidemia in metabolic syndrome and type 2 diabetes: therapeutic options beyond statins
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, The Chaim Sheba Medical Center, 52621 Tel Hashomer, Israel
    Cardiovasc Diabetol 5:20. 2006
    ....
  13. ncbi request reprint Effect of intensive resistance training on isotonic exercise Doppler indexes of left ventricular systolic function
    Enrique Z Fisman
    Cardiac Rehabilitation Institute, The Chaim Sheba Medical Center, Tel Hashomer, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Am J Cardiol 89:887-91. 2002
  14. pmc A cardiologic approach to non-insulin antidiabetic pharmacotherapy in patients with heart disease
    Enrique Z Fisman
    Sackler Faculty of Medicine, Tel Aviv University, 69978 Ramat Aviv, Tel Aviv, Israel
    Cardiovasc Diabetol 8:38. 2009
    ..In this context, it should be carefully taken into consideration whether the leading clinical status is CAD or heart failure...
  15. doi request reprint Non-insulin antidiabetic therapy in cardiac patients: current problems and future prospects
    Enrique Z Fisman
    Cardiovascular Diabetology Research Foundation, Holon, Israel
    Adv Cardiol 45:154-70. 2008
    ..New possibilities are represented by incretin mimetic compounds, dipeptidyl peptidase (DPP)-4 inhibitors, inhaled insulin and eventually oral insulin...
  16. doi request reprint Biomarkers in cardiovascular diabetology: interleukins and matrixins
    Enrique Z Fisman
    Cardiovascular Diabetology Research Foundation, Holon, Israel
    Adv Cardiol 45:44-64. 2008
    ..A pharmacologic simultaneous targeting of interleukins and matrixins might provide an effective means to concurrently control both atherosclerosis and diabetes...
  17. ncbi request reprint Systemic hypertension in postmenopausal women: a clinical approach
    Enrique Z Fisman
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, 52621 Tel Hashomer, Israel
    Curr Hypertens Rep 4:464-70. 2002
    ..Finally, education of both patients and physicians on the nature and prognosis of untreated hypertension is crucial...
  18. ncbi request reprint Is hypoglycaemia a marker for increased long-term mortality risk in patients with coronary artery disease? An 8-year follow-up
    Enrique Z Fisman
    Cardiac Rehabilitation Institute, Chaim Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Cardiovasc Prev Rehabil 11:135-43. 2004
    ..We aimed to investigate the relationship between hypoglycaemia and all-cause, cardiovascular and cancer mortality in a large population of patients with CAD...
  19. ncbi request reprint Impaired fasting glucose concentrations in nondiabetic patients with ischemic heart disease: a marker for a worse prognosis
    E Z Fisman
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, 526521 Tel Hashomer, Israel
    Am Heart J 141:485-90. 2001
    ..The current study evaluates the prognosis of nondiabetic patients with ischemic heart disease (IHD) and impaired fasting glucose (IFG) over a 7.7-year follow-up period...
  20. ncbi request reprint Prevalence and prognostic significance of unrecognized systemic hypertension in patients with diabetes mellitus and healed myocardial infarction and/or stable angina pectoris
    A Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Am J Cardiol 84:294-8. 1999
    ....
  21. ncbi request reprint Clinical impact of borderline and undiagnosed diabetes mellitus in patients with coronary artery disease
    A Tenenbaum
    Cardiac Rehabilitation Institute and the Bezafibrate Infarction Prevention Study Coordinating Center, Tel Hashomer, Israel
    Am J Cardiol 86:1363-6, A4-5. 2000
    ..but this tendency did not reach statistical significance. A significant excess in long-term mortality was observed among the undiagnosed diabetes group...
  22. ncbi request reprint Interleukin-6 and the risk of future cardiovascular events in patients with angina pectoris and/or healed myocardial infarction
    Enrique Z Fisman
    Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Am J Cardiol 98:14-8. 2006
    ..44; 95% confidence interval 1.57 to 8.13). In conclusion, elevated IL-6 levels are strongly associated with future cardiac events and mortality in a population with stable CAD during a long-term follow-up...
  23. ncbi request reprint Intermediate but not low doses of aspirin can suppress angiotensin-converting enzyme inhibitor-induced cough
    A Tenenbaum
    Cardiac Rehabilitation Institute and the Department of Internal Medicine D, The Chaim Sheba Medical Center, Tel Hashomer, Israel
    Am J Hypertens 13:776-82. 2000
    ..These findings propose a new alternative therapeutic approach for patients with ACEI-related cough, especially those in whom ACEI treatment seems to be essential...
  24. ncbi request reprint Advanced mitral annular calcification is associated with severe coronary calcification on fast dual spiral computed tomography
    A Tenenbaum
    Cardiac Rehabilitation Institute, The Chaim Sheba Medical Center, Tel Hashomer, Israel
    Invest Radiol 35:193-8. 2000
    ..The goal of the present study was to investigate whether an association between MAC and coronary calcification (CC) exists in hypertensive patients with increased cardiovascular risk...
  25. ncbi request reprint The acute effects of sublingual estradiol on left ventricular diastolic function in normotensive and hypertensive postmenopausal women
    E Z Fisman
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Maturitas 33:145-52. 1999
    ..limited information is available on estrogen influences on diastole. We aimed to investigate the acute effects of a single dose of sublingual 17beta-estradiol on left ventricular diastolic function in postmenopausal women...
  26. ncbi request reprint Antihyperglycemic treatment in diabetics with coronary disease: increased metformin-associated mortality over a 5-year follow-up
    E Z Fisman
    Cardiac Rehabilitation Institute, Neufeld Cardiac Research Institute, Chaim Sheba Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cardiology 91:195-202. 1999
    ..Until the results of problem-oriented prospective studies on oral control of NIDDM will be available, alternative therapeutic approaches should be investigated in these patients...
  27. ncbi request reprint Gender paradox in cardiac calcium deposits in middle-aged and elderly patients: mitral annular and coronary calcifications interrelationship
    A Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, 52621, Tel Hashomer, Israel
    Maturitas 36:35-42. 2000
    ..The goal of this work was to investigate gender influences on interrelationship between MAC and coronary calcifications (CC) in the same population of middle-aged and elderly patients with increased cardiovascular risk...
  28. ncbi request reprint Comparison of left ventricular function using isometric exercise Doppler echocardiography in competitive runners and weightlifters versus sedentary individuals
    E Z Fisman
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Am J Cardiol 79:355-9. 1997
    ..Athletes, taken as a group, react differently and adapt better than sedentary individuals. Moreover, among them, those involved in static sport show an improved cardiovascular adaptation to this type of exercise...
  29. ncbi request reprint Coronary artery disease but not coronary calcification is associated with elevated levels of cardiolipin, beta-2-glycoprotein-I, and oxidized LDL antibodies
    Y Sherer
    Department of Medicine 'B' and Center of Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel
    Cardiology 95:20-4. 2001
    ..046). CONCLUSION: Anti-CL, beta2GPI and oxLDL antibodies are elevated in coronary heart disease patients regardless of coronary calcification...
  30. doi request reprint Increased insulin resistance and risk of incident cerebrovascular events in patients with pre-existing atherothrombotic disease
    D Tanne
    Stroke Center, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Eur J Neurol 16:1217-23. 2009
    ..Our aim was to examine whether amongst patients with pre-existing atherothrombotic disease, increased insulin resistance is associated with incident cerebrovascular events...
  31. ncbi request reprint Usefulness of spiral computed tomography (dual-slice mode) for the detection of coronary artery calcium in patients with chronic atypical chest pain, in typical angina pectoris, and in asymptomatic subjects with prominent atherosclerotic risk factors
    J Shemesh
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel
    Am J Cardiol 87:226-8, A9. 2001
    ..The highest prevalence of coronary calcium was in men with angina pectoris (89%), whereas it was not detected in 48% of men and 56% of women with atypical chest pain...
  32. ncbi request reprint Attenuated responses of Doppler-derived hemodynamic parameters during supine bicycle exercise in heart transplant recipients
    I Auerbach
    Cardiac Rehabilitation Institute, Sheba Medical Center, Tel Hashomer, Israel
    Cardiology 92:204-9. 1999
    ..Our study demonstrates attenuated responses of basic hemodynamic parameters and Doppler-derived cardiovascular indices at symptom-limited supine bicycle exercise in heart transplant recipients compared to healthy volunteers...
  33. ncbi request reprint Long-term diuretic therapy in patients with coronary disease: increased colon cancer-related mortality over a 5-year follow-up
    A Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, 52621 Tel-Hashomer, Israel
    J Hum Hypertens 15:373-9. 2001
    ..15, 95% CI 1.15-8.65). CONCLUSION: Long-term exposure to diuretic therapy may be associated with an increased colon cancer-related mortality...
  34. ncbi request reprint The combined cough frequency/severity scoring: a new approach to cough evaluation in clinical settings
    E Z Fisman
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center Tel Hashomer, Israel
    J Med 32:181-7. 2001
    ..It may have important implications in the evaluation of patients with respiratory and cardiovascular disorders...
  35. ncbi request reprint Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Neufeld Cardiac Research Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Arch Intern Med 165:1154-60. 2005
    ..We evaluated the effect of bezafibrate retard, a fibric acid derivative, on the incidence of MI in patients with MS enrolled in the Bezafibrate Infarction Prevention (BIP) study...
  36. ncbi request reprint Autoantibodies to oxidized low-density lipoprotein in coronary artery disease
    Y Sherer
    Department of Medicine B, Sheba Medical Center, Tel-Hashomer, Israel
    Am J Hypertens 14:149-54. 2001
    ..CONCLUSIONS: Although the levels of oxLDL antibodies might be modified in early hypertension, once advanced coronary artery disease has developed the presence of hypertension does not affect anti-oxLDL levels...
  37. ncbi request reprint Blunted responses of doppler-derived aortic flow parameters during whole-body heavy isometric exercise in heart transplant recipients
    I Auerbach
    Cardiac Rehabilitation Institute, Sheba Medical Center, Tel Hashomer, Israel
    J Heart Lung Transplant 19:1063-70. 2000
    ..The aim of our study was to investigate the influences of whole-body, heavy, isometric exercise on Doppler-derived parameters in these patients...
  38. ncbi request reprint Attenuation of progression of insulin resistance in patients with coronary artery disease by bezafibrate
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Tel Hashomer, Israel
    Arch Intern Med 166:737-41. 2006
    ..The present analysis aimed to investigate the effect of bezafibrate on IR in patients with coronary artery disease enrolled in the Bezafibrate Infarction Prevention Study...
  39. doi request reprint Calcification of the thoracic aorta as detected by spiral computed tomography among stable angina pectoris patients: association with cardiovascular events and death
    Alon Eisen
    Cardiac Rehabilitation Institute, Talpiot Medical Leadership Program, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Circulation 118:1328-34. 2008
    ..The goal of the present study was to assess whether thoracic aorta calcification is associated with an increased risk of cardiovascular events and death in patients with stable angina pectoris...
  40. ncbi request reprint Neurocirculatory asthenia revisited: elevated arterial pressure at presentation is a marker for subsequent hypertension
    E Lev
    Institute of Endocrinology, Elias Sourasky Tel Aviv Medical Center, Ichilov Hospital, Tel Aviv, Israel
    J Intern Med 231:503-9. 1992
    ..Thus hypertension in this context is, as in the younger members of the population in general, a major risk factor for lifelong hypertension, rather than an inconsequential phenomenon...
  41. ncbi request reprint The acute effects of sublingual 17beta-estradiol on the cardiovascular system
    A Pines
    The Department of Medicine T, Ichilov Hospital, Tel Aviv, Israel
    Maturitas 33:81-5. 1999
    ....
  42. ncbi request reprint Clinical evidence of dose-dependent interaction between aspirin and angiotensin-converting enzyme inhibitors
    E Z Fisman
    Cardiac Rehabilitation Institute, The Chaim Sheba Medical Center, Tel Hashomer, and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Hum Hypertens 16:379-83. 2002
    ..We did not find any evidence supporting the presence of a clinically significant interaction between ACE-I and aspirin at 100 mg/day. Thus, combined treatment by low dose aspirin and ACE-I seems to be both safe and useful...
  43. ncbi request reprint Oral antidiabetic therapy in patients with heart disease. A cardiologic standpoint
    Enrique Z Fisman
    Cardiac Rehabilitation Institute, The Chaim Sheba Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Herz 29:290-8. 2004
    ....
  44. ncbi request reprint Coronary calcium by spiral computed tomography predicts cardiovascular events in high-risk hypertensive patients
    Joseph Shemesh
    Grace Ballas Research Unit of the Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer and, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Hypertens 22:605-10. 2004
    ..We aimed to investigate the hypothesis that CAC as assessed by dual slice spiral computed tomography (DSCT), is an independent risk factor for cardiovascular events in hypertensive patients...
  45. ncbi request reprint Functional class in patients with heart failure is associated with the development of diabetes
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Neufeld Cardiac Research Institute, The Chaim Sheba Medical Center, Tel Hashomer, 52621 Israel
    Am J Med 114:271-5. 2003
    ..We followed patients with coronary artery disease who participated in the Bezafibrate Infarction Prevention study to determine the incidence of diabetes by baseline functional status during a 7.7-year follow-up...
  46. ncbi request reprint Association of mitral annular calcium on spiral computed tomography (dual-slice mode) with thoracic aorta calcium in patients with systemic hypertension
    Yehuda Adler
    Cardiac Rehabilitation Institute, The Chaim Sheba Medical Center, Tel Hashomer, Israel
    Am J Cardiol 89:1420-2. 2002
  47. ncbi request reprint Retrograde embolism and atherosclerosis development in the human thoracic aorta: are the fluid dynamics explanations valid?
    A Tenenbaum
    Cardiac Rehabilitation Institute, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel
    Med Hypotheses 57:642-7. 2001
    ..Reversal and rotational blood-flow in the thoracic aorta most likely exist in all patients with systemic emboli and mobile protruding aortic atheromas. Therefore, retrograde cerebral embolism from distal aortic plaques is conceivable...
  48. ncbi request reprint Echocardiographic evaluation of the effects of gallopamil on left ventricular function
    E Z Fisman
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Clin Pharmacol Ther 44:100-6. 1988
    ..3% of the patients. In conclusion, gallopamil had no cardiodepressant effects in most patients. On the contrary, EF, PVR, and segmental contractility tended to improve with the higher doses...
  49. ncbi request reprint Does participation in a long-term clinical trial lead to survival gain for patients with coronary artery disease?
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Neufeld Cardiac Research Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Am J Med 112:545-8. 2002
    ....
  50. ncbi request reprint Coronary and aortic calcifications inter-relationship in stable angina pectoris: A Coronary Disease Trial Investigating Outcome with Nifedipine GITS (ACTION)--Israeli spiral computed tomography substudy
    Alon Eisen
    Cardiac Rehabilitation Institute, Department of Neurology, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 9:277-80. 2007
    ....
  51. ncbi request reprint Functional capacity impairment in patients with coronary artery disease: prevalence, risk factors and prognosis
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
    Cardiology 100:207-15. 2003
    ..The present study was aimed to evaluate the outcome of CAD-related functional capacity impairment in patients with and without a history of MI over a 7.7-year follow-up...
  52. ncbi request reprint Impact of the metabolic syndrome on the clinical outcomes of non-clinically diagnosed diabetic patients with acute coronary syndrome
    Micha S Feinberg
    Heart Institute, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Beer Sheba, Israel
    Am J Cardiol 99:667-72. 2007
    ..31) and 1.96 (95% confidence interval 1.18 to 3.24), respectively. In conclusion, MS defined early at admission is a strong independent predictor of mortality and morbidity in patients with non-clinically diagnosed diabetes with ACS...
  53. ncbi request reprint Calcification of the thoracic aorta by spiral computed tomography among hypertensive patients: associations and risk of ischemic cerebrovascular events
    David Tanne
    Stroke Center, Department of Neurology, Tel Hashomer, Israel
    Int J Cardiol 120:32-7. 2007
    ..Calcium is often deposited in the aorta, but the associations and clinical implications of calcification of the aorta have not yet been elucidated...
  54. doi request reprint Optimal management of combined dyslipidemia: what have we behind statins monotherapy?
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Adv Cardiol 45:127-53. 2008
    ....
  55. ncbi request reprint C-reactive protein as a predictor of incident ischemic stroke among patients with preexisting cardiovascular disease
    David Tanne
    Stroke Center, Department of Neurology and Sagol Neuroscience Center, Sheba Medical Center, Tel Hashomer, Israel
    Stroke 37:1720-4. 2006
    ..C-reactive protein (CRP) has emerged as an important predictor of cardiovascular disease, but there are few prospective data on its association with risk of ischemic stroke in patients at high risk...
  56. ncbi request reprint Insulin resistance is associated with increased risk of major cardiovascular events in patients with preexisting coronary artery disease
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Am Heart J 153:559-65. 2007
    ..The aim of our study was to explore the association between IR per se and cardiovascular events among patients with preexisting coronary artery disease...
  57. ncbi request reprint Macrovascular complications of metabolic syndrome: an early intervention is imperative
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, 52621 Tel Hashomer, Israel
    Int J Cardiol 97:167-72. 2004
    ....
  58. ncbi request reprint Effect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel
    Eur Heart J 26:2032-8. 2005
    ..To assess the effect of fibric acid derivative bezafibrate on incidence of type 2 diabetes in obese patients over a median 6.3 years follow-up period...
  59. ncbi request reprint Smoking and development of type 2 diabetes in patients with decreased functional capacity
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Int J Cardiol 104:275-81. 2005
    ..The present study was aimed to evaluate the association between cigarette smoking and development of type 2 diabetes in patients with coronary artery disease and decreased functional capacity over a 6.2-year follow-up period...
  60. ncbi request reprint Spiral computed tomography evidence of close correlation between coronary and thoracic aorta calcifications
    Yehuda Adler
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Sackler Faculty of Medicine, Tel Hashomer, Tel Aviv University, Tel Aviv, Israel
    Atherosclerosis 176:133-8. 2004
    ..26-5.08, P = 0.006) were identified as independent variables for the prediction of thoracic aorta calcification. Conclusions: Our study demonstrated a strong association of CC and calcification of the thoracic aorta on spiral CT...
  61. ncbi request reprint Peroxisome proliferator-activated receptor ligand bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer, 52621 Israel
    Circulation 109:2197-202. 2004
    ..2-year follow-up period...
  62. ncbi request reprint Impaired glucose metabolism in patients with heart failure: pathophysiology and possible treatment strategies
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Sheba Medical Center, Tel Hashomer, Israel
    Am J Cardiovasc Drugs 4:269-80. 2004
    ..Treatment with HMG-CoA reductase inhibitors should probably now be considered routinely for all diabetic patients with CHF, irrespective of their initial serum cholesterol levels, unless there is a contraindication...
  63. ncbi request reprint Aortic valve calcium on spiral computed tomography is associated with calcification of the thoracic aorta in hypertensive patients
    Yehuda Adler
    Cardiac Rehabilitation Institute, The Chaim Sheba Medical Center, Tel Hashomer, Israel
    Am J Cardiol 89:632-5. 2002
  64. ncbi request reprint Combined coronary and mitral annulus calcium detection in the non-invasive diagnosis of coronary artery disease in patients with systemic hypertension
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Coron Artery Dis 13:113-7. 2002
    ....
  65. ncbi request reprint Status of glucose metabolism in patients with heart failure secondary to coronary artery disease
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Tel Aviv, Israel
    Am J Cardiol 90:529-32. 2002
  66. ncbi request reprint Aortic valve calcification in hypertensive patients: prevalence, risk factors and association with transvalvular flow velocity
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Int J Cardiol 94:7-13. 2004
    ....
  67. ncbi request reprint Usefulness of helical computed tomography in detection of mitral annular calcification as a marker of coronary artery disease
    Yehuda Adler
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel
    Int J Cardiol 101:371-6. 2005
    ..The goal of the present work was to investigate whether helical CT can determine the presence of MAC and to clarify its possible association with coronary artery disease (CAD) in elderly patients...
  68. ncbi request reprint Autoantibodies to cardiolipin and beta-2-glycoprotein-I in coronary artery disease patients with and without hypertension
    Yaniv Sherer
    Department of Medicine B and Center of Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cardiology 97:2-5. 2002
    ..Elevated levels of both antibodies have been reported in hypertension. Nonetheless, there are no data regarding an association between these autoantibodies and hypertension in coronary artery disease...
  69. ncbi request reprint Aortic valve calcium on spiral computed tomography (dual slice mode) is associated with advanced coronary calcium in hypertensive patients
    Yehuda Adler
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Israel
    Coron Artery Dis 13:209-13. 2002
    ..The goal of the present study was to determine whether an association exists between the presence of AVC and coronary calcium (CC) in high-risk hypertensive patients as detected by spiral computed tomography (dual slice mode) (DHCT)...
  70. doi request reprint Left ventricular diastolic function in trained male weight lifters at rest and during isometric exercise
    Yehuda Adler
    Cardiac Rehabilitation Institute, Sheba Medical Center, Tel Hashomer, Israel
    Am J Cardiol 102:97-101. 2008
    ..0001 for all). In conclusion, intense resistance training leads to enhanced LV diastolic function at rest and during isometric exercise despite the markedly increased LV mass...
  71. ncbi request reprint ACE Inhibition with moexipril: a review of potential effects beyond blood pressure control
    Amos Pines
    Department of Medicine T, Ichilov Hospital, Tel Aviv University, Tel Aviv 64239, Israel
    Am J Cardiovasc Drugs 3:351-60. 2003
    ..Moreover, quality-of-life data suggest favorable effects of moexipril treatment in a patient population at high cardiovascular risk...
  72. ncbi request reprint Efficacy of omega-3 fatty acid supplementation in primary and secondary prevention of coronary heart disease
    Dalit Weisman
    Cardiac Rehabilitation Institute, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 6:227-32. 2004
  73. ncbi request reprint Long-term versus intermediate-term supervised exercise training in advanced heart failure: effects on exercise tolerance and mortality
    Alexander Tenenbaum
    Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Int J Cardiol 113:364-70. 2006
    ..We assessed exercise tolerance and mortality in CHF patients undergoing long- versus intermediate-term exercise training (ET)...
  74. ncbi request reprint Cardiovascular management of Marfan syndrome
    Michael Motro
    Ringers Unit for Clinical Cardiac Research, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 10:182-5. 2008
  75. ncbi request reprint Ischemic preconditioning: nearly two decades of research. A comprehensive review
    Alon Eisen
    Cardiac Rehabilitation Institute and Heart Failure Unit, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Atherosclerosis 172:201-10. 2004
    ..Administration of these mimetic drugs or procedures could potentially advance the use of preconditioning as a therapeutic tool and/or preventive factor for cardiovascular disease...
  76. ncbi request reprint Long-term effect of bezafibrate on pancreatic beta-cell function and insulin resistance in patients with diabetes
    Helena Tenenbaum
    Endocrinology and Diabetes Unit, Dan Petah Tikva District, Clalit Health Services, Israel
    Atherosclerosis 194:265-71. 2007
    ..The present study was aimed to investigate the long-term effect of bezafibrate on these parameters in diabetic patients enrolled in the Bezafibrate Infarction Prevention (BIP) Study...
  77. ncbi request reprint [Type 2 diabetes mellitus and cardiovascular diseases: evaluation, treatment and prevention strategies]
    Morris M Mosseri
    Heart Institute, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Harefuah 145:141-6, 164. 2006
    ..This article reviews the current and emerging therapeutic strategies for these purposes from the cardiologists' point of view...
  78. ncbi request reprint Effects of peroxisome proliferator-activated receptor ligands, bezafibrate and fenofibrate, on adiponectin level
    Aki Hiuge
    Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, 2 2, B5, Yamada oka, Suita, Osaka 565 0871, Japan
    Arterioscler Thromb Vasc Biol 27:635-41. 2007
    ..Effect of fibrates on adiponectin has not been clarified, whereas thiazolidinediones enhance adiponectin. Thus, we explored the possibility and mechanism that fibrates enhance adiponectin in humans, mice, and cells...
  79. ncbi request reprint Rhabdomyolysis and lipid-lowering drugs
    Alexander Tenenbaum
    JAMA 293:1448; author reply 1448-9. 2005
  80. ncbi request reprint Bezafibrate and simvastatin: different beneficial effects for different therapeutic aims
    Alexander Tenenbaum
    J Clin Endocrinol Metab 89:1978; author reply 1978-9. 2004
  81. ncbi request reprint C-reactive protein, bezafibrate, and recurrent coronary events in patients with chronic coronary heart disease
    Moti Haim
    Cardiology Department, Rabin Medical Center, Petach Tiqva, Israel
    Am Heart J 154:1095-101. 2007
    ....
  82. ncbi request reprint Cardiovascular diabetology: clinical, metabolic and inflammatory facets. Preface
    Enrique Z Fisman
    Adv Cardiol 45:xi-xiii. 2008
  83. ncbi request reprint Toward a redefinition of ischemic cardiomyopathy: is it an indivisible entity?
    Alexander Tenenbaum
    J Am Coll Cardiol 40:205-6; author reply 206. 2002