A Roguin

..The method is designed to seamlessly integrate into the routine catheterisation procedures and provide information to assist in decision making during the interventional procedure...

..DNA damage is considered to be the main initiating event by which radiation damage to cells results in development of cancer...

..EPCs tolerate oxidative stress by upregulating superoxide dismutase (SOD), the enzyme that neutralizes superoxide anion (O2-). Therefore, we investigated the roles of NO and SOD in glucose-stressed EPCs...

..This may have major clinical implications on current imaging practice. A strategy for the performance of MR imaging in these individuals is proposed...

..In 1959, with Dr. Rexford Kennamer and others, he published their first observations on the variant form of angina pectoris, a landmark report that was to ensure him a place in the annals of medicine. This report describes his life...

..Laënnec perfected the art of physical examination of the chest and introduced many clinical terms still used today...

..This is the description of a patient with an ICD who had planned MRI scanning. The scan was safe and most of the MRI images were of high quality...

..This report presents the life and work of Wilhelm His Jr., who was described by his colleagues as "a master of his profession, a great physician, investigator, and a well cultured gentleman."..

..Nikolai Korotkoff was the first to observe the sounds made by the constriction of the artery in 1905...

..The lesions were treated with stents. We present a case report to illustrate how newer technology such as CT angiography alters the way in which we diagnose CAD and decide on whether to pursue further invasive therapy...

..However, the role of cardiac MDCT is not yet determined in the medical community and, consequently, many clinically unnecessary scans are performed solely on a self-referral basis...

..Bazett's scientific work was largely concerned with temperature control, circulation, and blood volume, and he contributed greatly to the study of circulation in humans by using invasive catheterization...

..This review provides an update on the current status, review the major trials and define the clinical utility of small vessel stenting, particularly in the era of drug-eluting stents...

..In recent years there is an increase use of simulators especially for carotid artery stenting. However, most simulators use "generic" predefined cases...

..CTs were performed, and an eccentric calcific plaque was imaged at the ostium of the left main. Based on all three image modalities after discussing the different therapeutic options with the patient he was referred for bypass surgery...

..0 mm stents coated with phosphorylcholine appears to be safe and efficacious in the treatment of complex coronary lesions and is associated with low target vessel revascularization rate in spite of the very small vessel diameter...

..We sought to recapitulate the effect of Hp type on outcomes and cardiac remodeling after MI in transgenic mice...

..This study was designed to assess the feasibility and safety of a Remote Navigation System (RNS, NaviCath, Haifa, Israel) in which the angioplasty guidewire, the balloon, and the stent are navigated via a computerized system...

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..Endothelial progenitor cells (EPCs) contribute to the maintenance of vascular endothelial function. The moderate consumption of red wine provides cardiovascular protection...

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..The goal of this study was to determine whether the haptoglobin (Hp) genotype was predictive of restenosis and major adverse cardiac events (MACEs) after percutaneous transluminal coronary angioplasty (PTCA) in individuals with diabetes...

..We sought to evaluate the diagnostic utility and safety of noncardiac and cardiac MRI at 1.5T using a protocol that incorporates device selection and programming and limits the estimated specific absorption rate of MRI sequences...

..Obesity is strongly associated with elevated CRP levels, potentially confounding the relationship between CRP and CAD severity...

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..Our results are consistent with evidence that measures of central obesity, compared with body mass index, are more strongly related to clinical as well as subclinical coronary heart disease end points...

..Late events in the entire group were predicted by total occlusion at baseline...

..CONCLUSIONS: These data suggest that certain modern pacemaker and ICD systems may indeed be MRI safe. This may have major clinical implications for current imaging practices...

..CONCLUSION: Given appropriate precautions, MRI can be safely performed in patients with a selected permanent pacemaker. This may have significant implications for current MRI contraindications...

..This technique limited plaque shifting, restored normal flow to all vessels, including the LIMA, and avoided devastating consequences of VA occlusion...

..In this study, we sought to test the feasibility of performing electrophysiology studies with real-time MRI guidance...

..Finally, among patients with diabetes, Hp 1-1 was associated with smaller infarct size. This study demonstrates that in patients with diabetes and AMI, the Hp type is an important determinant of clinical outcome and infarct size...

..Haptoglobin 2-2 may predispose to less compensation for coronary artery stenosis in diabetic patients, and thereby portend a worse prognosis...

..He was a genius whose discoveries had a pivotal role in advancing us into the modern era...

..This feature also best distinguished ARVD/C (diffuse and localized) from RVOT. CONCLUSIONS: A prolonged S-wave upstroke in V1 through V3 is the most frequent ECG finding in ARVD/C and should be considered as a diagnostic ECG marker...

..Limitations include implantable cardioverter-defibrillators and motion artifacts, along with well-known radiation and contrast-induced reaction...

..There is limited data on the outcome of patients who undergo primary percutaneous coronary intervention and have transient hyperglycemia...

..The purpose of this study was to assess the physiologic significance of coronary artery lesions with an integrated single-photon emission computed tomography (SPECT) and computed tomography coronary angiography (CTCA) device...

..23 to 101.24, p = 0.031). CONCLUSIONS: Patients with ARVD/C have a high arrhythmia rate requiring appropriate ICD interventions. The ICD therapy appears to be well tolerated and important in the management of patients with ARVD/C...

..Diagnosis of ARVD/C cannot rely solely upon qualitative features on MRI...

..We sought to demonstrate the incidence of LVT after AMI in patients treated with PPCI compared with those treated with thrombolysis or with conservative management...

..If so, 40 million years of Spalax evolution underground, including adaptive hypoxia tolerance, may prove important to human angiogenic gene therapy...

..The article reviews the role of EPCs as markers for atherosclerosis and cardiovascular outcomes and highlights possible novel strategies to interfere with the balance of injury and repair mechanisms...

..These results underscore the role of systemic inflammation in the pathogenesis of periprocedural myocardial injury...

..However, the substrate for ventricular arrhythmia in patients with nonischemic cardiomyopathy remains poorly understood. We hypothesized that the distribution of scar identified by MRI is predictive of inducible ventricular tachycardia...

..Further research is needed to confirm that a low-risk subset of patients who may not require ICD placement can be identified...

..002). CONCLUSION: Advanced age, renal dysfunction, and female gender remain important risk factors for ischemic and bleeding complications in patients undergoing PCI with bivalirudin...

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..54-7.69; p=0.003). Our data suggest that complete myocardial revascularization may improve the long-term prognosis after PCI of diabetic patients with multivessel CAD...

..Our pilot data suggests that this imaging modality may potentially offer better sensitivity as compared to rest ECG in detecting ischemia in a cohort of patients who had coronary narrowings identified by angiography...

..15 to 0.75; p = 0.008) for patients in the third CRP tertile (p for trend = 0.008). In conclusion, an inverse graded association exists between CRP and the presence of coronary collaterals in patients with stable angina pectoris...

..Refinement of this strategy may allow for delivery of painless shocks by ICDs. Further development is needed to overcome implant complexity and the higher external DFT with this type of electrode system...

..Diagnosis is often delayed. Once diagnosed and treated with an ICD, mortality is low. There is a wide variation in presentation and course of ARVD patients, which can likely be explained by the genetic heterogeneity of the disease...

..In this study, we report results of quantitative evaluation of biventricular global and regional function using peak ejection rate and peak filling rate as measures of systolic and diastolic function, respectively (volumetric method)...

..Assessment of CACS may provide incremental value to global risk assessment in high-risk Brazilian men...

..To our knowledge, this is the first description of an acute MI in a sibling with a coronary artery occlusion in the exact anatomy as of the mother, occurring just several hours after the mother's coronary angiography...

..There are few published studies and no randomized trial has yet been performed in this specific group of patients...