Affiliation: Technion-Israel Institute of Technology
- Gonadotropin-releasing hormone-regulated prohibitin mediates apoptosis of the gonadotrope cellsDana Savulescu
Faculty of Biology, Technion Israel Institute of Technology, Haifa, 32000 Israel
Mol Endocrinol 27:1856-70. 2013..We thus demonstrate a role for PHB in GnRH-induced cell death in mature gonadotropes, which is crucial for the normal development and function of the reproductive axis. ..
- Hormonal signaling to follicle stimulating hormone beta-subunit gene expressionPhilippa Melamed
Faculty of Biology, Technion Israel Institute of Technology, Haifa, Israel
Mol Cell Endocrinol 314:204-12. 2010....
- Calcineurin mediates the gonadotropin-releasing hormone effect on expression of both subunits of the follicle-stimulating hormone through distinct mechanismsLilach Pnueli
Technion Israel Institute of Technology, Haifa, Israel
Mol Cell Biol 31:5023-36. 2011..TORC may be part of an alternatively regulated pathway, possibly involving cross talk with other stimulatory hormones...
- Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin beta-subunit gene transcriptionZhuojuan Luo
Technion Israel Institute of Technology, Haifa 32000, Israel
Mol Cell Biol 30:745-63. 2010..Our results suggest that Pin1 functions as a novel player in GnRH-induced signal pathways and is involved in gonadotropin beta-subunit gene transcription by modulating the activity of various specific transcription factors...