Efrati Shai

Summary

Country: Israel

Publications

  1. ncbi request reprint The effect of N-acetylcysteine on renal function, nitric oxide, and oxidative stress after angiography
    Shai Efrati
    Department of Medicine A, Division of Cardiology, Asaf Harofeh Medical Center, Zerifin, Israel
    Kidney Int 64:2182-7. 2003
  2. pmc Hyperbaric oxygen induces late neuroplasticity in post stroke patients--randomized, prospective trial
    Shai Efrati
    The Institute of Hyperbaric Medicine, Assaf Harofeh Medical Center, Zerifin, Israel
    PLoS ONE 8:e53716. 2013
  3. doi request reprint Hyperglycaemia emerging during general anaesthesia induces rat acute kidney injury via impaired microcirculation, augmented apoptosis and inhibited cell proliferation
    Shai Efrati
    Nephrology Division, Research and Development Unit, Assaf Harofeh Medical Center, Zerifin, Israel
    Nephrology (Carlton) 17:111-22. 2012
  4. ncbi request reprint PPAR-gamma activation inhibits angiotensin II synthesis, apoptosis, and proliferation of mesangial cells from spontaneously hypertensive rats
    Shai Efrati
    Nephrology Division, Department of Nephrology, Assaf Harofeh Medical Center, Zerifin, Israel
    Nephron Exp Nephrol 106:e107-12. 2007
  5. ncbi request reprint Rosiglitazone treatment attenuates expression of inflammatory hallmarks in the remaining kidney following contralateral nephrectomy
    Shai Efrati
    Nephrology Division, Assaf Harofeh Medical Center, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Zerifin, Israel
    Am J Nephrol 28:238-45. 2008
  6. doi request reprint Application of normobaric hyperoxia therapy for amelioration of haemorrhagic shock-induced acute renal failure
    Shai Efrati
    Division of Nephrology, Assaf Harofeh Medical Center, Zerifin 70300, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel
    Nephrol Dial Transplant 23:2213-22. 2008
  7. doi request reprint Differential effects of N-acetylcysteine, theophylline or bicarbonate on contrast-induced rat renal vasoconstriction
    Shai Efrati
    Research and Development Department, Assaf Harofeh Medical Center, Zerifin, Israel
    Am J Nephrol 29:181-91. 2009
  8. doi request reprint Carotid atherosclerotic disease following childhood scalp irradiation
    Efrati Shai
    Research and Development Unit, Assaf Harofeh Medical Center, Zerifin, Affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Atherosclerosis 204:556-60. 2009
  9. doi request reprint Rosiglitazone treatment attenuates renal tissue inflammation generated by urinary tract obstruction
    Shai Efrati
    Nephrology Division, Assaf Harofeh Medical Center, Zerifin, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel
    Nephrology (Carlton) 14:189-97. 2009
  10. doi request reprint Tracheal pressure and endotracheal tube obstruction can be detected by continuous cuff pressure monitoring: in vitro pilot study
    Shai Efrati
    Research and Development Unit, Assaf Harofeh Medical Center, Zerifin, Sackler School of Medicine, Tel Aviv University, Zerifin, Israel
    Intensive Care Med 36:984-90. 2010

Collaborators

Detail Information

Publications33

  1. ncbi request reprint The effect of N-acetylcysteine on renal function, nitric oxide, and oxidative stress after angiography
    Shai Efrati
    Department of Medicine A, Division of Cardiology, Asaf Harofeh Medical Center, Zerifin, Israel
    Kidney Int 64:2182-7. 2003
    ..We examined the hypothesis that NAC protected against contrast-induced renal impairment through effects on nitric oxide metabolism and oxidative stress...
  2. pmc Hyperbaric oxygen induces late neuroplasticity in post stroke patients--randomized, prospective trial
    Shai Efrati
    The Institute of Hyperbaric Medicine, Assaf Harofeh Medical Center, Zerifin, Israel
    PLoS ONE 8:e53716. 2013
    ..The current study aimed to evaluate whether increasing the level of dissolved oxygen by Hyperbaric Oxygen Therapy (HBOT) could activate neuroplasticity in patients with chronic neurologic deficiencies due to stroke...
  3. doi request reprint Hyperglycaemia emerging during general anaesthesia induces rat acute kidney injury via impaired microcirculation, augmented apoptosis and inhibited cell proliferation
    Shai Efrati
    Nephrology Division, Research and Development Unit, Assaf Harofeh Medical Center, Zerifin, Israel
    Nephrology (Carlton) 17:111-22. 2012
    ..We investigated the role of anaesthesia-triggered systemic hyperglycaemia in impairment of renal functioning, renal tissue injury, intra-renal Angiotensin-II synthesis and endogenous insulin production in anaesthetized rats...
  4. ncbi request reprint PPAR-gamma activation inhibits angiotensin II synthesis, apoptosis, and proliferation of mesangial cells from spontaneously hypertensive rats
    Shai Efrati
    Nephrology Division, Department of Nephrology, Assaf Harofeh Medical Center, Zerifin, Israel
    Nephron Exp Nephrol 106:e107-12. 2007
    ....
  5. ncbi request reprint Rosiglitazone treatment attenuates expression of inflammatory hallmarks in the remaining kidney following contralateral nephrectomy
    Shai Efrati
    Nephrology Division, Assaf Harofeh Medical Center, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Zerifin, Israel
    Am J Nephrol 28:238-45. 2008
    ..We applied rosiglitazone to attenuate inflammatory processes ongoing within the remaining kidney following contralateral nephrectomy...
  6. doi request reprint Application of normobaric hyperoxia therapy for amelioration of haemorrhagic shock-induced acute renal failure
    Shai Efrati
    Division of Nephrology, Assaf Harofeh Medical Center, Zerifin 70300, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel
    Nephrol Dial Transplant 23:2213-22. 2008
    ..Application of normobaric hyperoxia therapy (NHT) is an acceptable treatment for acute haemorrhagic shock. We investigated the effect of NHT on amelioration of haemorrhagic shock-induced rat renal failure...
  7. doi request reprint Differential effects of N-acetylcysteine, theophylline or bicarbonate on contrast-induced rat renal vasoconstriction
    Shai Efrati
    Research and Development Department, Assaf Harofeh Medical Center, Zerifin, Israel
    Am J Nephrol 29:181-91. 2009
    ..We compared the effects of N-acetylcysteine (NAC), theophylline or sodium bicarbonate on intrarenal vasoconstriction and ROS generation in a rat model of CM-induced nephropathy...
  8. doi request reprint Carotid atherosclerotic disease following childhood scalp irradiation
    Efrati Shai
    Research and Development Unit, Assaf Harofeh Medical Center, Zerifin, Affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Atherosclerosis 204:556-60. 2009
    ..We investigated the possible association between childhood low dose scalp irradiation and development of carotid atherosclerosis in adulthood...
  9. doi request reprint Rosiglitazone treatment attenuates renal tissue inflammation generated by urinary tract obstruction
    Shai Efrati
    Nephrology Division, Assaf Harofeh Medical Center, Zerifin, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel
    Nephrology (Carlton) 14:189-97. 2009
    ..Inflammation significantly aggravates renal injury following urinary tract obstruction. The effect of rosiglitazone on renal inflammation following unilateral ureteral obstruction was investigated...
  10. doi request reprint Tracheal pressure and endotracheal tube obstruction can be detected by continuous cuff pressure monitoring: in vitro pilot study
    Shai Efrati
    Research and Development Unit, Assaf Harofeh Medical Center, Zerifin, Sackler School of Medicine, Tel Aviv University, Zerifin, Israel
    Intensive Care Med 36:984-90. 2010
    ..To evaluate whether the degree of endotracheal tube (ETT) obstruction can be predicted by changes of ETT cuff pressure (P (c)) as a function of peak inspiratory pressure...
  11. doi request reprint Ventilator-associated pneumonia: current status and future recommendations
    Shai Efrati
    Research and Development Unit, Assaf Harofeh Medical Center, affiliated with the Sackler School of Medicine, Tel Aviv University, Zerifin, 70300, Israel
    J Clin Monit Comput 24:161-8. 2010
    ..Ventilator-associated pneumonia (VAP) is a common hazardous complication in ICU patients. The aim of the current review is to give an update on the current status and future recommendations for VAP prevention...
  12. doi request reprint Effect of captopril treatment on recuperation from ischemia/reperfusion-induced acute renal injury
    Shai Efrati
    Research and Development Unit, Assaf Harofeh Medical Center, Zerifin 70300, Tel Aviv University, Israel
    Nephrol Dial Transplant 27:136-45. 2012
    ..We investigated the role of angiotensin-converting enzyme (ACE) inhibition on the progression of AKI in a rat model of ischemia/reperfusion...
  13. doi request reprint Endotracheal tube cuff--small important part of a big issue
    Shai Efrati
    Research and Development Unit, Assaf Harofeh Medical Center, 70300, Zerifin, Israel
    J Clin Monit Comput 26:53-60. 2012
    ..The article challenges the present paradigm of cuff use and reviews the current clinical practice in that area...
  14. ncbi request reprint Enhanced angiotensin II production by renal mesangium is responsible for apoptosis/proliferation of endothelial and epithelial cells in a model of malignant hypertension
    Shai Efrati
    Division of Nephrology, Assaf Harofeh Medical Center, Zerifin, Israel
    J Hypertens 25:1041-52. 2007
    ..However, the intrarenal RAS might be at least equally important. We investigated the relationship between intrarenal RAS and mesangial, epithelial and endothelial cell proliferation/apoptosis in a model of malignant hypertension...
  15. ncbi request reprint N-acetylcysteine attenuates NSAID-induced rat renal failure by restoring intrarenal prostaglandin synthesis
    Shai Efrati
    Nephrology Division, Research and Development Unit, Department of Internal Medicine A, Assaf Harofeh Medical Center, Zerifin 70300, and Sackler Faculty of Medicine, Tel Aviv University, Israel
    Nephrol Dial Transplant 22:1873-81. 2007
    ..N-acetylcysteine (NAC) has renoprotective properties. We examined effects of NAC in a rat model of NSAID-induced renal failure...
  16. ncbi request reprint The effect of simvastatin, ezetimibe and their combination on the lipid profile, arterial stiffness and inflammatory markers
    S Efrati
    Department of Medicine A, Assaf Harofeh Medical Center, Zerifin, Israel
    Eur J Clin Pharmacol 63:113-21. 2007
    ..The aim of this study was to compare the effect of simvastatin and ezetimibe, both singly and in combination, on arterial stiffness and hsCRP serum concentration in hypercholesterolemic patients...
  17. ncbi request reprint Hyperbaric oxygen therapy for nonhealing vasculitic ulcers
    S Efrati
    The Institute of Hyperbaric Medicine and Wound Care Clinic, Assaf Harofeh Medical Center, Zerifin, Israel
    Clin Exp Dermatol 32:12-7. 2007
    ..Hyperbaric oxygen (HBO), frequently used as adjuvant therapy for patients with ischaemic ulcers, exerts additional beneficial effects on the vascular inflammatory response...
  18. doi request reprint Hyperglycemia alters renal cell responsiveness to pressure in a model of malignant hypertension
    Shai Efrati
    Research and Development Department, Assaf Harofeh Medical Center, Zerifin, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel
    J Hypertens 27:365-75. 2009
    ..We investigated responsiveness to pressure of various renal cell subsets subjected to hyperglycemic environment in an in-vitro model of malignant hypertension...
  19. ncbi request reprint Apoptosis and proliferation of cultured mesangial cells isolated from kidneys of rosiglitazone-treated pregnant diabetic rats
    Joshua Weissgarten
    Nephrology Division, Assaf Harofeh Medical Center, Zerifin 70300, Israel
    Nephrol Dial Transplant 21:1198-204. 2006
    ....
  20. doi request reprint Nutritional and inflammatory status of hemodialysis patients in relation to their body mass index
    Ilia Beberashvili
    Division of Nephrology, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Zerifin, Israel
    J Ren Nutr 19:238-47. 2009
    ..The study tested whether obese hemodialysis (HD) patients have a better nutritional and inflammatory state than those with overweight or normal body mass index (BMI)...
  21. ncbi request reprint Renal functional deterioration is not affected by the magnitude of sodium consumption in a normotensive model of moderate renal failure
    Joshua Weissgarten
    Division of Nephrology, Assaf Harofeh Medical Center, Zerifin, Israel
    Am J Nephrol 25:541-7. 2005
    ..We evaluated the effects of exaggerated dietary sodium and the resultant increase in proteinuria on renal function deterioration in experimental tubulointerstitial disease in rats...
  22. ncbi request reprint Apoptosis and proliferation of mesangial cells isolated from kidneys undergoing compensatory growth following contralateral nephrectomy: role of the renin-angiotensin system
    Joshua Weissgarten
    Nephrology Division, Assaf Harofeh Medical Center, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel
    Med Sci Monit 13:BR16-23. 2007
    ..The proliferation and apoptosis of cultured rat mesangial cells isolated from the remaining kidney following contralateral nephrectomy were evaluated. The involvement of the renin-angiotensin system was concomitantly assessed...
  23. ncbi request reprint N-Acetylcysteine ameliorates lithium-induced renal failure in rats
    Shai Efrati
    Department of Medicine A, Assaf Harofeh Medical Center, Zerifin, Israel
    Nephrol Dial Transplant 20:65-70. 2005
    ..The purpose of this study was to examine a possible renoprotective effect of NAC against lithium-induced renal failure in a rat model...
  24. ncbi request reprint Association between rosiglitazone use and decline in renal function in patients with type 2 diabetes mellitus
    Leonid Feldman
    Nephrology Division, Assaf Harofeh Medical Center, Zerifin Israel
    J Nephrol 23:350-6. 2010
    ..The aim of this study is to investigate the association between rosiglitazone use and renal function in diabetic patients...
  25. ncbi request reprint Early onset of hyperkalemia in patients treated with low molecular weight heparin: a prospective study
    Maya Koren-Michowitz
    Department of Medicine A, Assaf Harofe Medical Center, Zerifin, Israel
    Pharmacoepidemiol Drug Saf 13:299-302. 2004
    ..Data on low molecular weight heparin (LMWH) and induction of hyperkalemia is scarce. Therefore, we conducted a prospective study evaluating potassium levels before and after three days of treatment with the LMWH Enoxaparin...
  26. ncbi request reprint Hypertension but not sodium intake determines progression of renal failure in experimentally uremic rats
    Joshua Weissgarten
    Nephrology Division, Assaf Harofeh Medical Center, Zerifin, Israel
    Nephron Physiol 98:p1-7. 2004
    ..We studied the effect of high sodium consumption on progression of rat experimental renal failure while sodium-induced hypertension was pharmacologically controlled...
  27. doi request reprint The effect of levothyroxine on arterial stiffness and lipid profile in patients with subclinical hypothyroidism
    Ronit Koren Peleg
    Department of Internal Medicine A, Assaf Harofeh Medical Center, Zerifin, Israel
    Thyroid 18:825-30. 2008
    ..The aim of this study was to evaluate the effect of levothyroxine on arterial stiffness, lipid profile, and inflammation...
  28. ncbi request reprint Optimization of endotracheal tube cuff filling by continuous upper airway carbon dioxide monitoring
    Shai Efrati
    Department of Medicine A, Assaf Harofeh Medical Center, Zerifin, 70300, Israel
    Anesth Analg 101:1081-8, table of contents. 2005
    ..2 +/- 3.6 versus 18.2 +/- 7.8 mm Hg, respectively; P < 0.001). According to these findings, optimal ETT cuff filling pressure can be identified by monitoring P(CO2) at the nares or the oropharynx...
  29. ncbi request reprint Hyperbaric oxygen, oxidative stress, NO bioavailability and ulcer oxygenation in diabetic patients
    S Efrati
    The Institute of Hyperbaric Medicine and Wound Care Clinic, Nephrology Division, Research and Development Unit, Assaf Harofeh Medical Center Zerifin, Israel
    Undersea Hyperb Med 36:1-12. 2009
    ..Hyperbaric oxygen therapy (HBO2) increases tissue oxygenation, thus serving as an adjunct therapy for diabetic wounds. However, in some patients there is insufficient increase in tissue O2...
  30. ncbi request reprint Control of hypertension with captopril affords better renal protection as compared with irbesartan in salt-loaded uremic rats
    Joshua Weissgarten
    Nephrology Division, Assaf Harofeh Medical Center, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Zerifin, Israel
    Nephron Physiol 101:p14-20. 2005
    ..We investigated the effects of a high-sodium (HS) diet on the progression of renal failure in rats maintained normotensive by angiotensin-converting enzyme inhibition or AT-1 blockade...
  31. ncbi request reprint N-acetylcysteine ameliorates amphotericin-induced nephropathy in rats
    Leonid Feldman
    Nephrology Division, Assaf Harofeh Medical Center Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Zerifin, Israel
    Nephron Physiol 99:p23-7. 2005
    ..Amphotericin B may cause acute reduction in renal function. N-acetylcysteine (NAC) has a renoprotective activity in several nephrotoxic renal insults, but its effect on amphotericin-induced renal failure has not been investigated yet...
  32. ncbi request reprint Effect of various clinical variables on total intracellular magnesium in hospitalized normomagnesemic diabetic patients before discharge
    Oleg Gorelik
    Department of Internal Medicine F, Assaf Harofeh Medical Center, Sackler School of Medicine, Tel Aviv University, Ramat Aviv, Zerifin 70300, Israel
    Biol Trace Elem Res 120:102-9. 2007
    ..In conclusion, icMg is depleted in normomagnesemic DM patients. Insulin treatment is associated with worsening of icMg status, while metformin treatment may confer protective effect...
  33. doi request reprint Clinical variables affecting survival in patients with decompensated diastolic versus systolic heart failure
    Oleg Gorelik
    Department of Internal Medicine F, Assaf Harofeh Medical Center Affiliated to Sackler School of Medicine, Tel Aviv University, Zerifin, Israel
    Clin Res Cardiol 98:224-32. 2009
    ..The impact of various clinical variables on long-term survival of patients with acutely decompensated diastolic heart failure (DHF) compared to systolic heart failure (SHF) has not been sufficiently investigated...