Research Topics
| D TurnerSummaryAffiliation: Shaare Zedek Medical Center Country: Israel Publications
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Detail Information
Publications
Using the entire cohort in the receiver operating characteristic analysis maximizes precision of the minimal important differenceDan Turner
Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, Jerusalem, Israel
J Clin Epidemiol 62:374-9. 2009..We compared the minimal important difference (MID) values obtained by the receiver operating characteristics (ROC) curve approach using different strategies on four outcome measures to guide the optimal use of ROC curve...
Appraisal of the pediatric ulcerative colitis activity index (PUCAI)Dan Turner
Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, Jerusalem, Israel
Inflamm Bowel Dis 15:1218-23. 2009..We evaluated the psychometric performance of the Pediatric Ulcerative Colitis Activity Index (PUCAI) in a real-life cohort from the Pediatric IBD Collaborative Research Group...
A systematic prospective comparison of noninvasive disease activity indices in ulcerative colitisDan Turner
Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, Hebrew University of Jerusalem, POB 3235, Jerusalem 91031, Israel
Clin Gastroenterol Hepatol 7:1081-8. 2009..We performed a prospective study to systematically compare all non-invasive disease activity indices in patients with UC and to identify cutoff scores that correspond to remission and response...
Assessing disease activity in ulcerative colitis: patients or their physicians?Dan Turner
Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, Jerusalem, Israel
Inflamm Bowel Dis 16:651-6. 2010..We aimed to determine the optimal approach to assess disease activity (i.e., biological inflammation) in ulcerative colitis (UC) by comparing patients' and physicians' rating of the disease...
[Recommendations for the diagnosis and management of pediatric acute gastroenteritis in Israel]Dan Turner
Pediatric Gastroenterology and Nutrition Unit, Shaare Zedek Medical Center, Hebrew University of Jerusalem, Israel
Harefuah 149:53-8, 61, 60. 2010..Nearly all children will experience at least one episode of acute gastroenteritis (AGE) by the age of three years. Acute gastroenteritis is a common cause of admissions to the pediatric wards in Israel, but usually the disease is mild...
C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) or both? A systematic evaluation in pediatric ulcerative colitisDan Turner
Pediatric Gastroenterology and Nutrition Unit, Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Israel
J Crohns Colitis 5:423-9. 2011..There has not been an extensive comparison of CRP and ESR in ulcerative colitis (UC), and thus, we aimed to explore their utility in UC...
Glucocorticoid bioactivity does not predict response to steroid therapy in severe pediatric ulcerative colitisDan Turner
Shaare Zedek Medical Center, Jerusalem, Israel
Inflamm Bowel Dis 16:469-73. 2010..In this multicenter prospective study, we aimed to evaluate whether CS bioavailability plays a role in CS refractoriness in severe pediatric UC...
Pico-Salax versus polyethylene glycol for bowel cleanout before colonoscopy in children: a randomized controlled trialD Turner
Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, University of Toronto, Toronto, Canada
Endoscopy 41:1038-45. 2009..Comparison of bowel preparation for colonoscopy in children with either Pico-Salax (sodium picosulphate with magnesium citrate) or polyethylene glycol with electrolyte solution (PEG-ELS)...
Appraisal of the pediatric Crohn's disease activity index on four prospectively collected datasets: recommended cutoff values and clinimetric propertiesDan Turner
Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Jerusalem, Israel
Am J Gastroenterol 105:2085-92. 2010..The aim of this study was to provide knowledge on its performance and accuracy of different cutoff scores...
Maintenance of remission in inflammatory bowel disease using omega-3 fatty acids (fish oil): a systematic review and meta-analysesDan Turner
Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, Hebrew University of Jerusalem, Israel
Inflamm Bowel Dis 17:336-45. 2011..01-1.84) and symptoms of the upper gastrointestinal tract (RR 1.96; 95% CI: 1.37-2.80) in the n-3 treatment group. There are insufficient data to recommend the use of omega 3 fatty acids for maintenance of remission in CD and UC...
Acute severe ulcerative colitis in children: a systematic reviewDan Turner
Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel
Inflamm Bowel Dis 17:440-9. 2011....
Evidence-based recommendations for bowel cleansing before colonoscopy in children: a report from a national working groupD Turner
Pediatric Gastroenterology and Nutrition Unit, Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Israel
Endoscopy 42:1063-70. 2010..The Israeli Society of Pediatric Gastroenterology and Nutrition (ISPGAN) established an iterative working group to formulate evidence-based guidelines for bowel cleansing in children prior to colonoscopy...
Faecal calprotectin, lactoferrin, M2-pyruvate kinase and S100A12 in severe ulcerative colitis: a prospective multicentre comparison of predicting outcomes and monitoring responseD Turner
Paediatric Gastroenterology and Nutrition Unit, Shaare Zedek Medical Center, The Hebrew University of Jerusalem, POB 3235, Jerusalem 91031, Israel
Gut 59:1207-12. 2010..To compare four faecal markers for their ability to predict steroid refractoriness in severe paediatric ulcerative colitis (UC). Construct validity and responsiveness to change were also assessed...
Consensus for managing acute severe ulcerative colitis in children: a systematic review and joint statement from ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHANDan Turner
Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Jerusalem, Israel
Am J Gastroenterol 106:574-88. 2011....
Mathematical weighting of the pediatric Crohn's disease activity index (PCDAI) and comparison with its other short versionsDan Turner
Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, Hebrew University of Jerusalem, Israel
Inflamm Bowel Dis 18:55-62. 2012....
Mathematical weighting of a clinimetric index (Pediatric Ulcerative Colitis Activity Index) was superior to the judgmental approachDan Turner
Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, University of Toronto, Toronto, Canada
J Clin Epidemiol 62:738-44. 2009..We aimed to compare the judgmental and mathematical approaches in weighting the Pediatric Ulcerative Colitis Activity Index (PUCAI)...
Severe paediatric ulcerative colitis: incidence, outcomes and optimal timing for second-line therapyD Turner
Division of Pediatric Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, 555 University Avenue, Toronto, M5G 1X8, Canada
Gut 57:331-8. 2008..We reviewed rates and predictors of response to intravenous-corticosteroid therapy in a single-centre cohort with long-term follow-up...
Development, validation, and evaluation of a pediatric ulcerative colitis activity index: a prospective multicenter studyDan Turner
Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, University of Toronto, Toronto, Canada
Gastroenterology 133:423-32. 2007..Colonoscopic appearance, the primary measure of disease activity in adult ulcerative colitis, is less acceptable to children. Our aim was to develop a noninvasive activity index of pediatric ulcerative colitis...
The minimal detectable change cannot reliably replace the minimal important differenceDan Turner
Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, Jerusalem 91031, Israel
J Clin Epidemiol 63:28-36. 2010..We compared the minimal important difference (MID) with the minimal detectable change (MDC) generated by distribution-based methods...
Toxic megacolon in children with inflammatory bowel disease: clinical and radiographic characteristicsEric I Benchimol
Division of Gastroenterology, Hepatology and Nutrition, The Hospital of Sick Children, Toronto, Canada
Am J Gastroenterol 103:1524-31. 2008..This study assessed the clinical and radiologic characteristics of TMC in children with IBD...
Sweat gland bioelectrics differ in cystic fibrosis: a new concept for potential diagnosis and assessment of CFTR function in cystic fibrosisT Gonska
Department of Paediatrics, University of Toronto, Toronto, Canada
Thorax 64:932-8. 2009..A novel concept is proposed that may provide a more efficient real-time method for assessing CFTR function in vivo...
Severe acute ulcerative colitis: the pediatric perspectiveDan Turner
Pediatric Gastroenterology Unit, Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Jerusalem 91031, Israel
Dig Dis 27:322-6. 2009....
Response to corticosteroids in severe ulcerative colitis: a systematic review of the literature and a meta-regressionDan Turner
Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Canada
Clin Gastroenterol Hepatol 5:103-10. 2007..We aimed to systematically review studies that reported the short-term colectomy rate in severe UC or reported variables that could predict treatment failure...
Protein-tyrosine phosphatase sigma is associated with ulcerative colitisAleixo M Muise
Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Toronto, 555 University Ave, Toronto, Ontario, Canada
Curr Biol 17:1212-8. 2007..We propose that polymorphisms in the human PTPRS gene lead to ulcerative colitis...
Severe pediatric ulcerative colitis: a prospective multicenter study of outcomes and predictors of responseDan Turner
Shaare Zedek Medical Center, Jerusalem, Israel
Gastroenterology 138:2282-91. 2010..In a prospective study of children with severe ulcerative colitis (UC), we aimed to assess outcomes and to identify predictors of nonresponse to intravenous corticosteroids...
Esophageal, gastric, and duodenal manifestations of IBD and the role of upper endoscopy in IBD diagnosisDan Turner
Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Hospital for Sick Children, 555 University Avenue, Toronto, M5G 1X8, Canada
Curr Gastroenterol Rep 9:475-8. 2007..Infliximab therapy for upper GI-CD seems as effective as that seen for more distal GI inflammation...
Derivation of a clinical prediction rule for the noninvasive diagnosis of varices in childrenJuan Cristóbal Gana
Division of Gastroenterology, Hepatology and Nutrition, Shaare Zedek Medical Center, Hebrew University of Jerusalem, Israel
J Pediatr Gastroenterol Nutr 50:188-93. 2010..The objective of the study was to derive a noninvasive clinical prediction rule that is able to identify children with esophageal varices...
Low levels of procalcitonin during episodes of necrotizing enterocolitisDan Turner
Department of Pediatrics, Shaare Zedek Medical Center, Jerusalem, Israel
Dig Dis Sci 52:2972-6. 2007..1 ng/ml. We conclude that low procalcitonin values are the rule during episodes of NEC and provide further evidence that overactive local immune response, and not active infection, is primarily responsible for the mucosal damage in NEC...
Procalcitonin in preterm infants during the first few days of life: introducing an age related nomogramD Turner
Department of Pediatrics, Shaare Zedek Medical Center, Jerusalem, Israel
Arch Dis Child Fetal Neonatal Ed 91:F283-6. 2006..To determine normal concentrations of procalcitonin in preterm infants shortly after birth and to assess its accuracy in detecting bacterial infection...
The role of procalcitonin as a predictor of nosocomial sepsis in preterm infantsDan Turner
Departments of Pediatrics, Shaare Zedek Medical Center, Jerusalem, Israel
Acta Paediatr 95:1571-6. 2006..To assess the role of procalcitonin in detecting nosocomial sepsis in preterm infants, after the onset of clinical symptoms...
Hemolytic uremic syndrome after pediatric liver transplantationDan Turner
Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
J Pediatr Gastroenterol Nutr 43:109-12. 2006
Methotrexate following unsuccessful thiopurine therapy in pediatric Crohn's diseaseDan Turner
Division of Gastroenterology, Hepatology, and Nutrition, The Hospital for Sick Children, University of Toronto, Toronto, Canada
Am J Gastroenterol 102:2804-12; quiz 2803, 2813. 2007..We report outcomes with methotrexate treatment in pediatric patients previously refractory to or intolerant of thiopurines...
