Research Topics
| Einat PelesSummaryCountry: Israel Publications
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Publications
Melatonin for perceived sleep disturbances associated with benzodiazepine withdrawal among patients in methadone maintenance treatment: a double-blind randomized clinical trialEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Addiction 102:1947-53. 2007..To evaluate the effectiveness of melatonin in attenuating sleep difficulties during benzodiazepine (BDZ) withdrawal...
Tricyclic antidepressants abuse, with or without benzodiazepines abuse, in former heroin addicts currently in methadone maintenance treatment (MMT)Einat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Israel
Eur Neuropsychopharmacol 18:188-93. 2008..To measure suspected abuse of the tricyclic antidepressant amitriptyline among methadone maintenance treatment (MMT) patients in Israel, we studied cross-sectionally, all our 303 patients (February, 2007)...
Association of OCD with a history of traumatic events among patients in methadone maintenance treatmentEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
CNS Spectr 14:547-54. 2009..We studied the relationship between obsessive-compulsive disorder (OCD) and lifetime history of any traumatic events among methadone maintenance treatment (MMT) patients...
Duration of methadone maintenance treatment during pregnancy and pregnancy outcome parameters in women with opiate addictionEinat Peles
Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv Sourasky Medical Center, 1 Henrietta Szold Street, Tel Aviv 64924, Israel
J Addict Med 6:18-23. 2012..We studied the effect of the timing of starting MMT and of MMT related drug abstinence on the outcome of newborns of former and current opiate-addicted pregnant women...
Psychiatric comorbidity of patients on methadone maintenance treatment with a history of sexual abuseEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse Treatment and Research, Tel Aviv Sourasky Medical Center, 1 Henrietta Szold Street, 64924 Tel Aviv, Israel Department of Psychiatry, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Electronic address
Eur Neuropsychopharmacol 22:883-91. 2012..Those with cPTSD were characterized by more negative life events, higher dissociation scores, and assaults by a family member. We conclude that sexually abused MMT patients should be screened for clinical OCD...
Attention deficit hyperactivity disorder and obsessive-compulsive disorder among former heroin addicts currently in methadone maintenance treatmentEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv, Israel
Psychopathology 45:327-33. 2012....
15-Year survival and retention of patients in a general hospital-affiliated methadone maintenance treatment (MMT) center in IsraelEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, 1 Henrietta Szold Street, Tel Aviv 64924, Israel
Drug Alcohol Depend 107:141-8. 2010..Benzodiazepine abuse reduced both retention and survival, emphasizing the high priority that should be given to stopping it...
One-year and cumulative retention as predictors of success in methadone maintenance treatment: a comparison of two clinics in the United States and IsraelEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for DrugAbuse, Treatment and Research, Tel Aviv Sourasky Medical Center, Israel
J Addict Dis 27:11-25. 2008..The two major predictors in the two clinics were successful in both outcomes: 1 year retention and opiate abstinence...
Pathological gambling and obsessive compulsive disorder among methadone maintenance treatment patientsEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv, Israel
J Addict Dis 28:199-207. 2009..9%) in the sample, possibly because the clinic studied is of a higher severity than that accepted to the methadone maintenance treatment clinics in the community...
Characterization of former heroin addict patients with Hepatitis C virus antibodies in a methadone maintenance treatment (MMT) clinic in israelEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Subst Use Misuse 42:1477-84. 2007..To compare characteristics, retention in treatment and cessation of drug abuse of 249 positive hepatitis C (HCV+) with 188 negative hepatitis C (HCV-) antibody patients...
Pathological gambling in methadone maintenance clinics where gambling is legal versus illegalEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Am J Orthopsychiatry 80:311-6. 2010..Older age on admission to MMT, and male gender characterized PG in different MMT clinics, independent of the legal status of gambling. Low current PG rates for patients in both MMT clinics suggest that legality may not be relevant...
Earning "take-home" privileges and long-term outcome in a methadone maintenance treatment programEinat Peles
Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
J Addict Med 5:92-8. 2011....
No change of sleep after 6 and 12 months of methadone maintenance treatmentEinat Peles
Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
J Addict Med 5:141-7. 2011..To determine whether the methadone maintenance treatment (MMT) affects sleep...
Corrected-QT intervals as related to methadone dose and serum level in methadone maintenance treatment (MMT) patients: a cross-sectional studyEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatmentand Research, Tel Aviv, Israel
Addiction 102:289-300. 2007....
Depression in methadone maintenance treatment patients: rate and risk factorsEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
J Affect Disord 99:213-20. 2007..Depression is widely prevalent among former heroin addicts in methadone maintenance treatment (MMT). The risk factors for depression among MMT patients that have not been well characterized, was studied...
Gender differences and pregnant women in a methadone maintenance treatment (MMT) clinicEinat Peles
Clinic for Drug Abuse, Treatment and Research, Tel Aviv Elias Sourasky Medical Center, Tel Aviv, Israel
J Addict Dis 25:39-45. 2006..1 +/- 7.9, ANOVA F = 12.1, p = 0.001). We concluded that compared to males, females started MMT younger and had a higher proportion of cocaine abuse even though females' outcome were similar to males'...
Factors predicting retention in treatment: 10-year experience of a methadone maintenance treatment (MMT) clinic in IsraelEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv Elias Sourasky Medical Center, 6 Weizman Street, 64239 Tel Aviv, Israel
Drug Alcohol Depend 82:211-7. 2006..A protocol favoring higher methadone dosage as appropriate is recommended...
Variables associated with perceived sleep disorders in methadone maintenance treatment (MMT) patientsEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, Tel Aviv 64239, Israel
Drug Alcohol Depend 82:103-10. 2006..We concluded that sleep disorders should be evaluated and treated among MMT patients, particularly in those with psychiatric disorders, benzodiazepine abuse, chronic pain and high methadone dose...
Significantly higher methadone dose for methadone maintenance treatment (MMT) patients with chronic painEinat Peles
The Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv Elias Sourasky Medical Center, 1 Henrietta Szold Street, Tel Aviv 64924, Israel
Pain 113:340-6. 2005....
Documented poor sleep among methadone-maintained patients is associated with chronic pain and benzodiazepine abuse, but not with methadone doseEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse Treatment and Research, Tel Aviv Sourasky Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Eur Neuropsychopharmacol 19:581-8. 2009..Sleep evaluation and treatment should address these two prevalent conditions in order to improve MMT patients' quality of sleep (and of life) and overall treatment outcome...
Sense of coherence as a stable predictor for methadone maintenance treatment (MMT) outcomeYali Abramsohn
Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, 1 Henrietta Szold St, Tel Aviv 64924, Israel
J Psychoactive Drugs 41:249-53. 2009..2-3.9) as compared with 60 patients with SOC scores of 130 or less (2.9 years, 95% CI 2.5-3.3). SOC is a stable parameter that can serve as a predictor for success in MMT, both as retention in treatment and drug abstinence...
Low risk for hepatitis C seroconversion in methadone maintenance treatmentEinat Peles
Tel Aviv University Sackler Faculty of Medicine, Tel Aviv, Israel
J Addict Med 5:214-20. 2011..To study the risk factors for seroconversion to hepatitis C virus (HCV) infection since admission to methadone maintenance treatment (MMT) and to characterize the seronegative admitted group...
Association between improvement in depression, reduced benzodiazepine (BDZ) abuse, and increased psychotropic medication use in methadone maintenance treatment (MMT) patientsShaul Schreiber
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv Sourasky Medical Center, 1 Henrietta Szold St, Tel Aviv 64924, Israel
Drug Alcohol Depend 92:79-85. 2008..0005). Predictors for being depressed at follow-up were pre-existing depression only. Stopping BDZ abuse and starting psychotropic treatment was associated with a reduction of depressive symptoms among MMT patients...
The differential effect of methadone dose and of chronic pain on pain perception of former heroin addicts receiving methadone maintenance treatmentEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv Sourasky Medical Center and Tel Aviv University Sackler Faculty of Medicine, Tel Aviv, Israel
J Pain 12:41-50. 2011..Studying the alteration in pain perception in these subjects may contribute to understanding the high rates of chronic pain among them and may promote better treatment...
Correlation between high methadone doses and methadone serum levels in methadone maintenance treatment (MMT) patientsMiriam Adelson
Tel Aviv Elias Sourasky Medical Center, 6, Weizman St, Tel Aviv, Israel
J Addict Dis 26:15-26. 2007..To evaluate the relation between high methadone doses and methadone serum levels in MMT patients...
Long waiting period to enter methadone maintenance treatment: relation to patient characteristics and outcomeEinat Peles
Dr Miriam and Sheldon G Adelson Clinic for Drug Abuse, Treatment and Research, Tel Aviv University Sackler Faculty of Medicine, Tel Aviv, Israel einatp tasmc health gov il
Eur Addict Res 18:149-52. 2012..The waiting list patient group was characterized by older age and self-referral - two known independent predictors of better retention that were attributed to their superior retention rate...
Long-lasting sleep patterns of adult patients with minor traumatic brain injury (mTBI) and non-mTBI subjectsShaul Schreiber
Department of Psychiatry, Tel Aviv Sourasky Medical Center and Tel Aviv University Sackler Faculty of Medicine, Tel Aviv 64239, Israel
Sleep Med 9:481-7. 2008..Sleep disturbance is a common subjective complaint of minor traumatic brain-injured (mTBI) patients, but little is known about the characteristics of sleep disturbance in adults years after the injury...
High methadone dose significantly reduces cocaine use in methadone maintenance treatment (MMT) patientsEinat Peles
Dr. Miriam and Sheldon G. Adelson Clinic for Drug Abuse, Treatment and Research, Tel-Aviv Elias Sourasky Medical Center, 1 Henrietta Szold St, Tel-Aviv, 64924, Israel
J Addict Dis 25:43-50. 2006..9+/-48.7 mg/day), or 242 who never used cocaine (119.5+/-48.4 mg/day) (ANOVA, F=15.6, p<0.0005). CONCLUSIONS: High methadone dose may reduce cocaine use in patients addicted to both heroin and cocaine...
Primary intervention for memory structuring and meaning acquisition (PIMSMA): study of a mental health first-aid intervention in the ED with injured survivors of suicide bombing attacksShaul Schreiber
Department of Psychiatry, Tel Aviv Sourasky Medical Center, Israel
Am J Disaster Med 2:307-20. 2007....
Management and outcome of non-traumatic cerebellar haemorrhageZvi R Cohen
Department of Neurosurgery, The Chaim Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
Cerebrovasc Dis 14:207-13. 2002....
Angiogenic factors in the cerebrospinal fluid of patients with astrocytic brain tumorsEinat Peles
Department of Neurosurgery, Sheba Medical Center, Tel-Hashomer and Tel Aviv University, Sackler School of Medicine, Tel Aviv, Israel
Neurosurgery 55:562-7; discussion 567-8. 2004..CONCLUSION: Our data suggest that CSF levels of bFGF and VEGF may serve as an additional marker for tumor grading and vascularity and may help predict survival...
ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependenceOrna Levran
Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, NY 10065, USA
Hum Mol Genet 17:2219-27. 2008..026). These data suggest that specific ABCB1 variants may have clinical relevance by influencing the methadone dose required to prevent withdrawal symptoms and relapse in this population...
