Moshe Nussinovitch

..In light of the encouraging results in these two patients, further studies are warranted regarding the value of lactic dehydrogenase isoenzyme measurements for follow-up purposes and for evaluations of response to treatment...

..The deep breath test is one of several measures used to assess the severity of autonomic diseases, but its value in familial dysautonomia has not yet been investigated...

..The present study of 24-hour ambulatory blood pressure monitoring in children with familial dysautonomia was carried out to investigate the pattern of blood pressure in this syndrome...

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..Further investigation of occult dysautonomia in FMF is needed...

..Otitis externa (OE), also known as "swimmer's ear", is an inflammation or infection of the external auditory canal. Many risk factors have been identified, mainly excessive moisture in the canal from swimming...

..FMF patients who are continuously treated with colchicine and do not develop amyloidosis have normal atrial conduction parameters and therefore seemingly do not have an increased electrocardiographic risk of atrial fibrillation...

..The aim of this study was to investigate the possibility that abnormal ambulatory blood pressure patterns may be indicative of malingering hypertension rather than hypertension itself...

..Infantile spasm is apparently associated with a distinct LDH isoenzyme pattern in the CSF. More studies are needed to confirm the rise in LDH-2, LDH-3 and to determine the optimum time of analysis...

..05). Both groups had low levels of LDH-1 and high levels of LDH-4 and LDH-5. In conclusion, the LDH isoenzyme pattern may be of clinical diagnostic value in meningitis, particularly when culture results are pending...

..In conclusion, patients with FMF who did not develop amyloidosis due to continuous colchicine treatment appeared to have normal autonomic function, as reflected by the normal response to physiological autonomic stimuli...

..Our aim was to evaluate whether a 10-second resting heart rate obtained from a resting electrocardiogram (ECG), could be used as a reliable evaluation of short-term HRV...

..Several studies have attempted to use shorter recordings of 1-2 minutes or 10 seconds. The aim of this study was to determine the reliability of HRV parameters calculated from ultra-short electrocardiogram recordings...

..Future research and longer follow-ups should be conducted in order to evaluate the prognostic importance of repolarization dispersion parameters in amyloidosis of FMF...

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..Unknown previously, cardiac remodeling or hypertrophy is common in FD. We recommend that routine cardiac echocardiography be performed in this population, and attempts to treat high blood pressure should begin earlier in life...

..Prevalence of hypertension, mostly primary, in a large cohort of students was 0.76%. Early screening is important for early interventions and reducing cardiovascular morbidity and mortality in adulthood...

..032). In conclusion, most QT dynamics parameters in patients with FD are similar to that of normal controls. Nevertheless, FD patients have significantly higher QTVN, which might indicate higher risk for ventricular arrhythmias...

..All late potential parameters were within normal range in both groups. In conclusion, patients with familial dysautonomia commonly have electrocardiographic abnormalities and may be at a higher risk for adverse cardiac events...

..Given the paucity of knowledge regarding the affects of eating disorders on cardiac depolarization, our aim was to further explore LPs in patients with eating disorders...

..Further studies are required to evaluate the influence of different disease stages, electrolyte imbalance and other medical complications on P wave parameters and risk for supraventricular arrhythmias in AN patients...

..The aim of the current study was to further evaluate repolarization dynamics in a large cohort of patients with AN without electrolyte abnormalities and to evaluate previously unreported repolarization dynamics parameters...

..001) and between the whole study group and the controls for LDH-2 and -3 (p <0.001). We propose reference values for total LDH activity and LDH isoenzyme distribution in the CSF of normal neonates...

..0 -/+ 1.3. No tooth staining was detected by the dentist in any of the children in either group. These findings indicate that treatment with doxycycline in children aged 2 to 8 years is not associated with tooth staining...

..Henoch-Schönlein purpura (HSP), also known as anaphylactoid purpura is a clinically recognizable systemic disorder occurring in children, mainly from ages 3 to 10 years...

..Findings indicate that this regimen might be a promising treatment option in this patient population. Larger, controlled trials are needed to reach a definitive conclusion...

..Multiple sclerosis appears to be characterized by an abnormal lactic dehydrogenase isoenzyme pattern in cerebrospinal fluid. The importance of this finding and its diagnostic potential use warrant further investigation...

..Autonomic tone also affects atrial conduction parameters and P-wave dispersion, which are predictive of atrial fibrillation...

..Genital FDE in children is uncommon, but the drugs associated with this entity are in such widespread use in pediatric practice that its recognition may be important, especially considering its easy treatability...

..The findings suggest that the absolute neutrophil count and the polymorphonuclear cell percentage in cerebrospinal fluid have different kinetics in aseptic vs. bacterial meningitis...

..These data emphasize the need for regular monitoring of children with HSP with or without renal findings...

..Imaging studies are needed only in atypical presentation or if there is no spontaneous improvement after 1 to 2 weeks...

..In this case a normal, healthy adolescent was treated with intravenous ceftriaxone without any of the known neurological complications observed in the neonatal cases...

..An estimated 10% of all children are subject to recurrent attacks of abdominal pain of unknown origin. When no organic cause is found, the working diagnosis is usually functional abdominal pain...

..Nevertheless, when neurologic findings are present, advanced imaging studies are needed to exclude intraspinal involvement...

..We compared the safety of high and low starting dose of budesonide by measuring their effect on plasma cortisol concentration...

..Awareness and recognition of this disease by pediatricians and its early diagnosis by a rapid-strep test will lead to appropriate treatment and prompt recovery...

..This study compared the effect of inhaled budesonide and inhaled fluticasone in controlling acute asthma exacerbations in young children at home...