B Modan

Summary

Country: Israel

Publications

  1. ncbi request reprint Parity, oral contraceptives, and the risk of ovarian cancer among carriers and noncarriers of a BRCA1 or BRCA2 mutation
    B Modan
    Department of Clinical Epidemiology, Chaim Sheba Medical Center, Tel Hashomer, Israel
    N Engl J Med 345:235-40. 2001
  2. ncbi request reprint Population attributes affecting the prevalence of BRCA mutation carriers in epithelial ovarian cancer cases in israel
    G Hirsh-Yechezkel
    Cancer Epidemiology Unit, Gertner Institute for Epidemiology and Health Policy Research, Tel Hashomer, Israel
    Gynecol Oncol 89:494-8. 2003
  3. ncbi request reprint Rates of Jewish ancestral mutations in BRCA1 and BRCA2 in borderline ovarian tumors
    W H Gotlieb
    Division of Gynecologic Oncology, Sheba Medical Center, and Sackler School of Medicine, Tel Aviv University, Tel Hashomer, Israel
    J Natl Cancer Inst 90:995-1000. 1998
  4. ncbi request reprint Risk factors for infant mortality in Down's syndrome: a nationwide study
    S Sadetzki
    Department of Clinical Epidemiology, Chaim Sheba Medical Center, Tel Aviv University Medical School, Tel Hashomer, Israel
    Paediatr Perinat Epidemiol 13:442-51. 1999
  5. pmc Prevalence of HIV antibodies in transsexual and female prostitutes
    B Modan
    Department of Clinical Epidemiology, Chaim Sheba Medical Center, Tel Hashomer, Tel Aviv University Medical School, Israel
    Am J Public Health 82:590-2. 1992
  6. ncbi request reprint Synergistic effects of prothrombotic polymorphisms and atherogenic factors on the risk of myocardial infarction in young males
    A Inbal
    Institute of Thrombosis and Hemostasis, Department of Hematology, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Blood 93:2186-90. 1999
  7. ncbi request reprint Morbidity, comorbidity, and their association with disability among community-dwelling oldest-old in Israel
    Z Fuchs
    Department of Clinical Epidemiology, Chaim Sheba Medical Center, Tel Hashomer, Israel
    J Gerontol A Biol Sci Med Sci 53:M447-55. 1998
  8. pmc An identical novel mutation in BRCA1 and a common haplotype in familial ovarian cancer in non-Ashkenazi Jews
    L Theodor
    Oncogenetics Unit, Institute of Genetics, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Br J Cancer 77:1880-3. 1998
  9. ncbi request reprint Body mass index at age 18 years and during adult life and ovarian cancer risk
    F Lubin
    Cancer Epidemiology Unit, Gertner Institute, Sheba Medical Center, Tel Hashomer, Israel
    Am J Epidemiol 157:113-20. 2003
  10. ncbi request reprint Characteristics of clients attending confidential versus anonymous testing clinics for human immunodeficiency virus
    I Levi
    Infectious Disease Unit, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 3:184-7. 2001

Detail Information

Publications25

  1. ncbi request reprint Parity, oral contraceptives, and the risk of ovarian cancer among carriers and noncarriers of a BRCA1 or BRCA2 mutation
    B Modan
    Department of Clinical Epidemiology, Chaim Sheba Medical Center, Tel Hashomer, Israel
    N Engl J Med 345:235-40. 2001
    ..Multiparity and the use of oral contraceptives reduce the risk of ovarian cancer, but their effects on this risk in women with a BRCA1 or BRCA2 mutation are unclear...
  2. ncbi request reprint Population attributes affecting the prevalence of BRCA mutation carriers in epithelial ovarian cancer cases in israel
    G Hirsh-Yechezkel
    Cancer Epidemiology Unit, Gertner Institute for Epidemiology and Health Policy Research, Tel Hashomer, Israel
    Gynecol Oncol 89:494-8. 2003
    ..The objective was to evaluate the prevalence of BRCA1/2 mutations in selected categories of ovarian cancer patients in Israel...
  3. ncbi request reprint Rates of Jewish ancestral mutations in BRCA1 and BRCA2 in borderline ovarian tumors
    W H Gotlieb
    Division of Gynecologic Oncology, Sheba Medical Center, and Sackler School of Medicine, Tel Aviv University, Tel Hashomer, Israel
    J Natl Cancer Inst 90:995-1000. 1998
    ..To gain insight into these issues, we determined the rates of 185delAG-BRCA1 and 6174delT-BRCA2 mutations in patients with borderline ovarian tumors...
  4. ncbi request reprint Risk factors for infant mortality in Down's syndrome: a nationwide study
    S Sadetzki
    Department of Clinical Epidemiology, Chaim Sheba Medical Center, Tel Aviv University Medical School, Tel Hashomer, Israel
    Paediatr Perinat Epidemiol 13:442-51. 1999
    ..The study identifies a potential for further reduction in the mortality rates of DS infants, provided there is willingness to adopt a more active and supportive treatment and further changes in ethical codes of the public...
  5. pmc Prevalence of HIV antibodies in transsexual and female prostitutes
    B Modan
    Department of Clinical Epidemiology, Chaim Sheba Medical Center, Tel Hashomer, Tel Aviv University Medical School, Israel
    Am J Public Health 82:590-2. 1992
    ..In contrast, 11.1% of the 36 male transsexuals (including 3 out of 32 non-drug abusers) were seropositive. The results support the notion that vaginal transmission of HIV is less effective than anal transmission...
  6. ncbi request reprint Synergistic effects of prothrombotic polymorphisms and atherogenic factors on the risk of myocardial infarction in young males
    A Inbal
    Institute of Thrombosis and Hemostasis, Department of Hematology, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Blood 93:2186-90. 1999
    ..7; 95% CI, 7.17 to 84.9). The presented data suggest a synergistic effect between atherogenic and thrombogenic risk factors in the pathogenesis of AMI, as was recently found in a similar cohort of women...
  7. ncbi request reprint Morbidity, comorbidity, and their association with disability among community-dwelling oldest-old in Israel
    Z Fuchs
    Department of Clinical Epidemiology, Chaim Sheba Medical Center, Tel Hashomer, Israel
    J Gerontol A Biol Sci Med Sci 53:M447-55. 1998
    ....
  8. pmc An identical novel mutation in BRCA1 and a common haplotype in familial ovarian cancer in non-Ashkenazi Jews
    L Theodor
    Oncogenetics Unit, Institute of Genetics, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Br J Cancer 77:1880-3. 1998
    ....
  9. ncbi request reprint Body mass index at age 18 years and during adult life and ovarian cancer risk
    F Lubin
    Cancer Epidemiology Unit, Gertner Institute, Sheba Medical Center, Tel Hashomer, Israel
    Am J Epidemiol 157:113-20. 2003
    ..The authors conclude that, in their population, body mass index at age 18 years is an independent risk factor for ovarian cancer...
  10. ncbi request reprint Characteristics of clients attending confidential versus anonymous testing clinics for human immunodeficiency virus
    I Levi
    Infectious Disease Unit, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 3:184-7. 2001
    ..To compare risk behavior between subjects attending anonymous and confidential clinics for human immunodeficiency virus testing, and to assess whether anonymous testing results in a higher accrual of persons at risk for HIV...
  11. ncbi request reprint Selected risk factors for transitional cell bladder cancer
    S Sadetzki
    Department of Clinical Epidemiology, Chaim Sheba Medical Center, Tel Hashomer, and Stanley Steyer Institute for Cancer Epidemiology and Research, Tel Aviv University Medical School, Israel
    Med Oncol 17:179-82. 2000
    ..82; 95% Cl=0.95-3.49). The above data suggest that current efforts to reduce the load of bladder cancer in the population, via environmental measures, have not as yet yielded significant effects...
  12. ncbi request reprint The role of nutritional habits during gestation and child life in pediatric brain tumor etiology
    F Lubin
    Department of Clinical Epidemiology, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Int J Cancer 86:139-43. 2000
    ..36; CI 1.06-1.73) in the child diet and potassium intake during gestation (OR = 1.44; CI 1.04-1.99). In conclusion, nutritional associations with pediatric brain tumor etiology, remain unsubstantiated...
  13. ncbi request reprint Hepatitis A outbreak originating in a day care center: a community case report
    S Sadetzki
    Department of Clinical Epidemiology, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Eur J Epidemiol 15:549-51. 1999
    ..The mode of transmission exemplified in this community underlines the difficulties in identifying a common source of hepatitis A infection, which is necessary for the elimination of a further spread of the disease...
  14. ncbi request reprint Incidence of leukemia and other cancers in Down syndrome subjects in Israel
    L K Boker
    Department of Clinical Epidemiology, Chaim Sheba Medical Center, Ramat Gan, Israel
    Int J Cancer 93:741-4. 2001
    ..Significant excess of leukemia in DS population in Israel is in accordance with previously published data. An excess of gastric cancer in DS male subjects born before 1979, which has not been reported before, should be further explored...
  15. pmc Radiation policy: a decision-making model
    B Modan
    Chaim Sheba Medical Center, Stanley Steyer Institute for Cancer Epidemiology and Research, Tel Aviv University, Israel
    Environ Health Perspect 105:1599-601. 1997
    ..Three case studies--nuclear plant workers, children irradiated for an essentially benign condition, and food safety--are used to illustrate polar policy decisions...
  16. ncbi request reprint The possible association between in vitro fertilization treatments and cancer development
    L Lerner-Geva
    Gertner Institute for Epidemiology and Health Policy Research, Chaim Sheba Medical Center Tel, Hashomer, Israel
    Int J Gynecol Cancer 13:23-7. 2003
    ..Special attention should be made to women who may be diagnosed with cancer during or shortly after IVF treatment...
  17. ncbi request reprint Frequency of BRCA mutations in primary peritoneal carcinoma in Israeli Jewish women
    J Menczer
    Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, E Wolfson Medical Center, Holon, Israel
    Gynecol Oncol 88:58-61. 2003
    ..The aim of the present study was to compare demographic and clinical characteristics of primary peritoneal carcinoma (PPC) to ovarian carcinoma (OvC) with regard to BRCA mutation frequencies...
  18. ncbi request reprint Effect of BRCA mutations on the length of survival in epithelial ovarian tumors
    Y Ben David
    Department of Gynecology, Haemek Medical Center, Afula
    J Clin Oncol 20:463-6. 2002
    ..To study the role of BRCA mutations in ovarian cancer survival...
  19. ncbi request reprint A single nucleotide polymorphism in the 5' untranslated region of RAD51 and risk of cancer among BRCA1/2 mutation carriers
    W W Wang
    Laboratory of Population Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 10:955-60. 2001
    ..The biochemical basis of this risk modifier is currently unknown...
  20. ncbi request reprint Physician visits, emergency room utilization, and overnight hospitalization in the old-old in Israel: the cross-sectional and longitudinal aging study (CALAS)
    A Walter-Ginzburg
    Geriatric Institute for Education and Research, Kaplan Hospital, Rehovot, Israel
    J Am Geriatr Soc 49:549-56. 2001
    ..The study indicates that equity in the provision of health services is attainable. Policy makers should provide for actual need, remove artificial barriers, and prepare accurate estimates of future needs...
  21. ncbi request reprint Selectively increased risk of cancer in men with coronary heart disease
    H Reicher-Reiss
    Heart Institute, Department of Epidemiology and Preventive Medicine, Sackler School of Medicine, Tel Aviv University, Israel
    Am J Cardiol 87:459-62, A6. 2001
    ..Higher total and age-specific incidence rates of cancer were observed among male coronary patients than among the Israeli male population, but this excess was limited to cancers of the lung, bladder, and colon...
  22. ncbi request reprint Analyses of p53 expression pattern and BRCA mutations in patients with double primary breast and ovarian cancer
    I Bruchim
    Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, Sapir Medical Center, Kfar Saba 44281, Israel
    Int J Gynecol Cancer 14:251-8. 2004
    ..To analyze the somatic pattern of p53 expression and BRCA germline mutation status in Israeli patients with both ovarian (OvCa) and breast cancer (BrCa)...
  23. ncbi request reprint Social factors and mortality in the old-old in Israel: the CALAS study
    Adrian Walter-Ginzburg
    Herczeg Institute on Aging, Tel Aviv University, Tel Aviv, Israel 69978
    J Gerontol B Psychol Sci Soc Sci 57:S308-18. 2002
    ....
  24. pmc Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease
    N Hamajima
    Cancer Research UK Epidemiology Unit, Gibson Building, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK
    Br J Cancer 87:1234-45. 2002
    ....
  25. ncbi request reprint Assistance with personal care activities among the old-old in Israel: a national epidemiological study
    A Walter-Ginzburg
    Herczeg Institute on Aging, Tel Aviv University, Tel Aviv, Israel
    J Am Geriatr Soc 49:1176-84. 2001
    ..This finding may imply underutilization of services, which should be investigated further to determine if it is caused by barriers to utilization or by the free choice of the disabled old-old and their families...