Research Topics
| A LyakhovitskySummaryCountry: Israel Publications
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Detail Information
Publications
Novel mutations in two families with Darier's diseaseB Amichai
Department of Dermatology, Huzot Clinic of Clalit Health Services, Ashkelon, Israel
Int J Dermatol 46:64-7. 2007..Deleterious mutations in the gene ATP2A2 which encodes SERCA2, a calcium pump of the sarco/endoplasmic reticulum underlie the disease...
Iontophoretic terbinafine HCL 1.0% delivery across porcine and human nailsBoaz Amichai
Huzot Clinic, Clalit Health Services, Ashkelon, Israel
Mycopathologia 169:343-9. 2010..Successful treatment of deep-seated nail infections remains elusive as the delivery of efficacious levels of antifungal drug to the site of action is very difficult...
Iontophoretic delivery of terbinafine in onychomycosis: a preliminary studyB Amichai
Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel
Br J Dermatol 162:46-50. 2010..Conclusions The delivery of terbinafine under an electrical current of 100 microA cm(-2) appears to be efficacious and safe and is well tolerated for the treatment of nail onychomycosis...
A rationale for systemic treatment in onychomycosis with negative results on fungal examinationB Amichai
Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel
Clin Exp Dermatol 36:724-7. 2011..Laboratory confirmation of fungal infection is currently accepted as a requirement before initiation of antifungal treatment in clinical practice...
A randomized, double-blind, placebo-controlled study to evaluate the efficacy in AD of liquid soap containing 12% ammonium lactate + 20% ureaB Amichai
Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel
Clin Exp Dermatol 34:e602-4. 2009..001) in the study group compared with the control group. The liquid soap was found to be effective in patients with AD, as use of this soap in patients with stable mild to moderate AD improved the parameters studied...
Cutaneous hyperpigmentation during therapy with hydroxychloroquineBoaz Amichai
Huzot Clinic, Clalit Health Services, Ashkelon, Israel
J Clin Rheumatol 13:113. 2007
Low-dose methotrexate treatment for moderate-to-severe atopic dermatitis in adultsA Lyakhovitsky
Sheba Medical Center Dermatology Department, Tel Hashomer, Ramat Gan, Israel
J Eur Acad Dermatol Venereol 24:43-9. 2010..This study assessed the efficacy and safety of treatment with low weekly doses of methotrexate for moderate-to-severe AD in adults...
Nail sampling in onychomycosis: comparative study of curettage from three sites of the infected nailAvner Shemer
Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel
J Dtsch Dermatol Ges 5:1108-11. 2007..The purpose of this study was to compare results of curettage technique of nail sampling in the diagnosis of onychomycosis from three different sites of the affected nail to establish the best location of sampling...
Onychomycosis in psoriatic patients - rationalization of systemic treatmentAvner Shemer
Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel
Mycoses 53:340-3. 2010..Considering the low response to onychomycosis systemic therapy in psoriatic patients and the potential side-effects of the treatment, the rationality of this treatment is questionable...
Onychomycosis: rationalization of topical treatmentAvner Shemer
Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel
Isr Med Assoc J 10:415-6. 2008..Fungal infection of the nail affects millions of people worldwide and has an estimated prevalence of more than 10% of the general population...
Comparative study of nail sampling techniques in onychomycosisAvner Shemer
Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel
J Dermatol 36:410-4. 2009..With each technique we found that the culture sensitivity improved as the location of the sample was more proximal. More types of pathogens were detected in samples taken by both methods from proximal parts of the affected nails...
Ciclopirox nail lacquer for the treatment of onychomycosis: an open non-comparative studyAvner Shemer
Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel
J Dermatol 37:137-9. 2010..No adverse effects were noted throughout the treatment period. Ciclopirox nail lacquer seems to be slightly more effective than other topical modalities and could be used in patients who cannot or do not want systemic treatment...
Treatment of moderate to severe facial seborrheic dermatitis with itraconazole: an open non-comparative studyAvner Shemer
Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel
Isr Med Assoc J 10:417-8. 2008..Seborrheic dermatitis is a common chronic disease. Malassezia yeasts have been implicated in the pathogenesis of this disease. Antifungal agents are known to be effective in the treatment of Malassezia yeast infections...
