Avi Livneh

Summary

Country: Israel

Publications

  1. doi request reprint Familial Mediterranean fever in children presenting with attacks of fever alone
    Shai Padeh
    Department of Pediatrics A, Edmond and Lily Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Israel
    J Rheumatol 37:865-9. 2010
  2. ncbi request reprint Chronic chilblains: the clinical presentation and disease course in a large paediatric series
    Shai Padeh
    Department of Pediatrics A, Edmond and Lily Safra Children s Hospital, Tel Hashomer, Israel
    Clin Exp Rheumatol 31:463-8. 2013
  3. doi request reprint Colchicine is a safe drug in children with familial Mediterranean fever
    Shai Padeh
    Department of Pediatrics, Edmond and Lily Safra Children s Hospital, Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    J Pediatr 161:1142-6. 2012
  4. ncbi request reprint Periodic fever accompanied by aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA syndrome) in adults
    Shai Padeh
    Department of Pediatrics A, Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 10:358-60. 2008
  5. doi request reprint Children with oligoarticular juvenile idiopathic arthritis are at considerable risk for growth retardation
    Shai Padeh
    Department of Pediatrics, Sackler School of Medicine, Tel Aviv University, Israel
    J Pediatr 159:832-837.e1-2. 2011
  6. ncbi request reprint Familial Mediterranean Fever in the first two years of life: a unique phenotype of disease in evolution
    Shai Padeh
    Department of Pediatrics A, Edmond and Lily Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Israel
    J Pediatr 156:985-9. 2010
  7. ncbi request reprint Clinical and diagnostic value of genetic testing in 216 Israeli children with Familial Mediterranean fever
    Shai Padeh
    Department of Pediatrics, Sheba Medical Center, Tel Hashomer, Israel
    J Rheumatol 30:185-90. 2003
  8. ncbi request reprint Analysis of the three most common MEFV mutations in 412 patients with familial Mediterranean fever
    Nurit Zaks
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 5:585-8. 2003
  9. ncbi request reprint Risk factors for amyloidosis and impact of kidney transplantation on the course of familial Mediterranean fever
    Ilan Ben-Zvi
    Rheumatology Unit, Zabludowicz Center of Autoimmune Disease, Tel Hashomer, Israel
    Isr Med Assoc J 14:221-4. 2012
  10. ncbi request reprint Arthritis as the sole episodic manifestation of familial Mediterranean fever
    Merav Lidar
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    J Rheumatol 32:859-62. 2005

Collaborators

Detail Information

Publications72

  1. doi request reprint Familial Mediterranean fever in children presenting with attacks of fever alone
    Shai Padeh
    Department of Pediatrics A, Edmond and Lily Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Israel
    J Rheumatol 37:865-9. 2010
    ..Our objective was clinical and genetic characterization of FMF and its development in pediatric patients who first presented with attacks of fever alone...
  2. ncbi request reprint Chronic chilblains: the clinical presentation and disease course in a large paediatric series
    Shai Padeh
    Department of Pediatrics A, Edmond and Lily Safra Children s Hospital, Tel Hashomer, Israel
    Clin Exp Rheumatol 31:463-8. 2013
    ..Pernio, or chronic chilblains, is a localised inflammatory lesion of the skin resulting from an abnormal response to cold. The aim of this study was to better characterise the clinical presentation of chronic chilblains in children...
  3. doi request reprint Colchicine is a safe drug in children with familial Mediterranean fever
    Shai Padeh
    Department of Pediatrics, Edmond and Lily Safra Children s Hospital, Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    J Pediatr 161:1142-6. 2012
    ..To identify any adverse effects of colchicine in a pediatric patients with familial Mediterranean fever (FMF)...
  4. ncbi request reprint Periodic fever accompanied by aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA syndrome) in adults
    Shai Padeh
    Department of Pediatrics A, Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 10:358-60. 2008
    ..It usually begins before the age of 5 years and in most cases resolves spontaneously before age 10...
  5. doi request reprint Children with oligoarticular juvenile idiopathic arthritis are at considerable risk for growth retardation
    Shai Padeh
    Department of Pediatrics, Sackler School of Medicine, Tel Aviv University, Israel
    J Pediatr 159:832-837.e1-2. 2011
    ..To assess linear growth in patients with persistent oligoarticular juvenile idiopathic arthritis (JIA) treated by intra-articular corticosteroid injections (IACSI)...
  6. ncbi request reprint Familial Mediterranean Fever in the first two years of life: a unique phenotype of disease in evolution
    Shai Padeh
    Department of Pediatrics A, Edmond and Lily Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Israel
    J Pediatr 156:985-9. 2010
    ..To characterize the clinical and genetic features of familial Mediterranean fever (FMF)...
  7. ncbi request reprint Clinical and diagnostic value of genetic testing in 216 Israeli children with Familial Mediterranean fever
    Shai Padeh
    Department of Pediatrics, Sheba Medical Center, Tel Hashomer, Israel
    J Rheumatol 30:185-90. 2003
    ..We appraised the value of mutation analysis as a diagnostic test for FMF in symptomatic pediatric patients, and explored the possible correlations between MEFV genotypes and the diverse phenotypic expression of the disease...
  8. ncbi request reprint Analysis of the three most common MEFV mutations in 412 patients with familial Mediterranean fever
    Nurit Zaks
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 5:585-8. 2003
    ..The disease is caused by mutations in the MEFV gene, presumed to act as a down-regulator of inflammation within the polymorphonuclear cells...
  9. ncbi request reprint Risk factors for amyloidosis and impact of kidney transplantation on the course of familial Mediterranean fever
    Ilan Ben-Zvi
    Rheumatology Unit, Zabludowicz Center of Autoimmune Disease, Tel Hashomer, Israel
    Isr Med Assoc J 14:221-4. 2012
    ..Amyloidosis of familial Mediterranean fever (FMF) may lead to end-stage renal failure, culminating in kidney transplantation in some patients...
  10. ncbi request reprint Arthritis as the sole episodic manifestation of familial Mediterranean fever
    Merav Lidar
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    J Rheumatol 32:859-62. 2005
    ....
  11. doi request reprint Role of the R92Q TNFRSF1A mutation in patients with familial Mediterranean fever
    Dina Marek-Yagel
    Sheba Medical Center, Ramat Gan, and Tel Aviv University, Ramat Aviv, Israel
    Arthritis Care Res (Hoboken) 62:1294-8. 2010
    ..To define the frequency of the R92Q tumor necrosis factor receptor-associated periodic syndrome (TRAPS) mutation in patients with familial Mediterranean fever (FMF) and to study the role of this mutation in FMF...
  12. doi request reprint Familial Mediterranean fever in Ashkenazi Jews: the mild end of the clinical spectrum
    Merav Lidar
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    J Rheumatol 37:422-5. 2010
    ..To characterize familial Mediterranean fever (FMF) in Ashkenazi patients, a Jewish subgroup in which FMF has rarely been described before...
  13. doi request reprint P wave dispersion in familial Mediterranean fever
    Naomi Nussinovitch
    Hypertension Unit and Department of Internal Medicine D, Sheba Medical Center, Tel Hashomer, Israel
    Rheumatol Int 31:1591-4. 2011
    ..FMF patients who are continuously treated with colchicine and do not develop amyloidosis have normal atrial conduction parameters and therefore seemingly do not have an increased electrocardiographic risk of atrial fibrillation...
  14. doi request reprint Normal autonomic nervous system responses in uncomplicated familial Mediterranean fever: a comparative case-control study
    Udi Nussinovitch
    The Heller Institute of Medical Research, and Department of Medicine F, Sheba Medical Center, Tel Hashomer, Israel, 52621
    Clin Rheumatol 30:1347-51. 2011
    ..In conclusion, patients with FMF who did not develop amyloidosis due to continuous colchicine treatment appeared to have normal autonomic function, as reflected by the normal response to physiological autonomic stimuli...
  15. doi request reprint The familial Mediterranean fever gene as a modifier of periodic fever, aphthous stomatitis, pharyngitis, and adenopathy syndrome
    Yackov Berkun
    Department of Pediatrics, Edmond and Lily Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Israel
    Semin Arthritis Rheum 40:467-72. 2011
    ..We aimed at investigating the effect of MEFV gene mutations on disease phenotype in PFAPA...
  16. doi request reprint Clinical disease among patients heterozygous for familial Mediterranean fever
    Dina Marek-Yagel
    Danek Gertner Institute of Human Genetics, Sheba Medical Center, Tel Hashomer, Israel, and Sackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel
    Arthritis Rheum 60:1862-6. 2009
    ..To define the molecular basis of familial Mediterranean fever (FMF) in patients with only 1 mutation in the MEFV gene...
  17. doi request reprint E148Q MEFV mutation carriage and longevity in individuals of Ashkenazi origin
    Merav Lidar
    Medicine F and Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Immunol Res 56:371-5. 2013
    ..Our findings suggest that E148Q carriage contributes to longevity in the Ashkenazi population, perhaps by enhancing resistance to infections...
  18. ncbi request reprint Familial Mediterranean fever and cryptogenic cirrhosis
    Nurit Tweezer-Zaks
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Medicine (Baltimore) 86:355-62. 2007
    ..Genetic analysis in patients with cryptogenic cirrhosis unrelated to FMF, particularly patients of a Mediterranean origin, may be warranted in future studies...
  19. doi request reprint QT dispersion in amyloidosis due to familial Mediterranean fever
    Udi Nussinovitch
    The Heller Institute of Medical Research, and Department of Medicine F, Sheba Medical Center, Tel Hashomer Israel and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Rheumatol Int 32:1945-8. 2012
    ..Future research and longer follow-ups should be conducted in order to evaluate the prognostic importance of repolarization dispersion parameters in amyloidosis of FMF...
  20. ncbi request reprint The familial Mediterranean fever (MEVF) gene as a modifier of Crohn's disease
    Herma Fidder
    Department of Gastroenterology and The Heller Institute of Medical Research, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Am J Gastroenterol 100:338-43. 2005
    ....
  21. doi request reprint Heart rate variability in familial Mediterranean fever
    Naomi Nussinovitch
    Hypertension Unit, Department of Internal Medicine D, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Rheumatol Int 31:39-43. 2011
    ..Further investigation of occult dysautonomia in FMF is needed...
  22. doi request reprint Free light chains in plasma of patients with light chain amyloidosis and non-amyloid light chain deposition disease. High proportion and heterogeneity of disulfide-linked monoclonal free light chains as pathogenic features of amyloid disease
    Batia Kaplan
    Heller Institute of Medical Research, Sheba Medical Centre, Tel Hashomer, Israel
    Br J Haematol 144:705-15. 2009
    ..The applied methods might be useful to diagnose or predict the pathological form of the disease and shed light on the mechanisms involved in light chain aggregation in tissues...
  23. ncbi request reprint Crohn disease in patients with familial Mediterranean fever
    Herma H Fidder
    Department of Gastroenterology, Chaim Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, TelHashomer, Israel
    Medicine (Baltimore) 81:411-6. 2002
    ..In conclusion, Crohn disease appears to be more prevalent in FMF and presents later than in patients without FMF. FMF in this group of patients shows a higher attack frequency and is more often complicated by amyloidosis...
  24. ncbi request reprint Colchicine nonresponsiveness in familial Mediterranean fever: clinical, genetic, pharmacokinetic, and socioeconomic characterization
    Merav Lidar
    Heller Institute of Medical Research, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer, Israel
    Semin Arthritis Rheum 33:273-82. 2004
    ..To identify the ethnic, clinical, genetic, and pharmacokinetic correlates of colchicine treatment failure in patients with familial Mediterranean fever (FMF)...
  25. doi request reprint Attempts at suppression of amyloidogenesis in a mouse model by a variety of anti-inflammatory agents
    Shmuel Shtrasburg
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Autoimmun Rev 12:18-21. 2012
    ..In the present study we have tried to determine the efficacy of a variety of anti-inflammatory agents at suppressing AA amyloidosis in a mouse model of the disease...
  26. doi request reprint Incomplete response to colchicine in M694V homozygote FMF patients
    Merav Lidar
    Department of Medicine F, Sheba Medical Center, Israel
    Autoimmun Rev 12:72-6. 2012
    ..Genotyping enables us to study the response rates according to specific mutations. We have witnessed a large number of M694V homozygotes who do not respond well to colchicine despite being treated with maximal sustained doses...
  27. doi request reprint Familial Mediterranean fever gene and protection against asthma
    Einat Rabinovitch
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Ann Allergy Asthma Immunol 99:517-21. 2007
    ....
  28. ncbi request reprint Evaluation of disease severity in familial Mediterranean fever
    Adam Mor
    Sheba Medical Center, Tel Hashomer and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Semin Arthritis Rheum 35:57-64. 2005
    ..To establish a new, objective, statistically based severity score for familial Mediterranean fever (FMF)...
  29. ncbi request reprint A single testing of serum amyloid a levels as a tool for diagnosis and treatment dilemmas in familial Mediterranean fever
    Yackov Berkun
    Department of Pediatrics, Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Israel
    Semin Arthritis Rheum 37:182-8. 2007
    ..The aim of the study was to determine various correlates of elevated SAA and evaluate the role of SAA measurement in the diagnosis and management of FMF...
  30. ncbi request reprint Severe gastrointestinal inflammation in adult dermatomyositis: characterization of a novel clinical association
    Nurit Tweezer-Zaks
    Rheumatic Diseases Unit, Sheba Medical Center and Sackler School of Medicine, Tel Aviv University, Israel
    Am J Med Sci 332:308-13. 2006
    ..Severe inflammation of the alimentary tract in cases of adult DM and PM is rare. The purpose of this study was to examine the prevalence and clinical characteristics of inflammatory gastrointestinal involvement in patients with DM...
  31. doi request reprint P-wave dispersion in systemic AA amyloidosis of familial Mediterranean fever
    Udi Nussinovitch
    The Heller Institute of Medical Research and Department of Medicine F, Sheba Medical Center, Tel Hashomer, Israel
    Clin Rheumatol 30:1295-8. 2011
    ....
  32. ncbi request reprint Interferon-alpha as a treatment modality for colchicine- resistant familial Mediterranean fever
    Nurit Tweezer-Zaks
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Rheumatol 35:1362-5. 2008
    ..We investigated the effect of IFN-alpha in patients with colchicine-resistant FMF...
  33. ncbi request reprint MEFV mutation carriage in Israeli Jewish individuals from ethnicities with low risk for familial Mediterranean fever
    Olga Feld
    Department of Medicine F, Sheba Medical Center, Heller Institute of Medical Research, Ramat Gan, Israel
    J Hum Genet 54:369-71. 2009
    ..MEFV mutation carriage in this subgroup is associated with various inflammatory disorders...
  34. ncbi request reprint Diagnostic value of the biochemical composition of pericardial effusions in patients undergoing pericardiocentesis
    Shomron Ben-Horin
    Department of Medicine F, Sheba Medical Center and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Am J Cardiol 99:1294-7. 2007
    ..In conclusion, most PEs are exudates. The analysis of pericardial fluid biochemical and cell-count composition is generally not helpful for the diagnosis of most PEs...
  35. doi request reprint Chronic inflammation in FMF: markers, risk factors, outcomes and therapy
    Ilan Ben-Zvi
    Department of Medicine F, Sheba Medical Center, Tel Hashomer 52621, Israel
    Nat Rev Rheumatol 7:105-12. 2011
    ....
  36. doi request reprint Diagnosis. Severity scoring system for paediatric FMF
    Avi Livneh
    Department of Medicine, Sheba Medical Centre, Tel Hashomer, Ramat Gan, Israel
    Nat Rev Rheumatol 8:309-10. 2012
    ..A recent paper highlights the need for a paediatric FMF severity measure. How should such a score be built and what challenges might be faced?..
  37. ncbi request reprint The prodrome: a prominent yet overlooked pre-attack manifestation of familial Mediterranean fever
    Merav Lidar
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer 52621, Israel
    J Rheumatol 33:1089-92. 2006
    ..To identify and characterize pre-attack symptoms (prodrome) in patients with familial Mediterranean fever (FMF)...
  38. ncbi request reprint Suppression of amyloidogenesis in a mouse model by corticosteroid intervention
    Shmuel Shtrasburg
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Isreal
    Transl Res 150:66-72. 2007
    ..These experiments show that corticosteroids may significantly suppress amyloidogenesis but only briefly and, therefore, discourage a long-term and late use of steroid supplement in different anti-amyloid treatment protocols...
  39. doi request reprint Isolation and biochemical characterization of plasma monoclonal free light chains in amyloidosis and multiple myeloma: a pilot study of intact and truncated forms of light chains and their charge properties
    Batia Kaplan
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Clin Chem Lab Med 46:335-41. 2008
    ..The present study focused on the development of the procedure for isolation and biochemical characterization of monoclonal FLC in small plasma specimens from patients with these disorders...
  40. doi request reprint Mortality risk factors associated with familial Mediterranean fever among a cohort of 1.25 million adolescents
    Gilad Twig
    Department of Medicine, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Ann Rheum Dis 73:704-9. 2014
    ..There are limited data on long-term comorbidities and mortality among patients with familial Mediterranean fever (FMF). Our objective was to evaluate comorbidities and death rates among individuals with FMF...
  41. ncbi request reprint Gastrointestinal beta2microglobulin amyloidosis in hemodialysis patients: biochemical analysis of amyloid proteins in small formalin-fixed paraffin-embedded tissue specimens
    Batia Kaplan
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Mod Pathol 18:1610-7. 2005
    ..The new methodology used might be useful in obtaining precise diagnosis of amyloidosis that is necessary for appropriate therapy, and also provide new important information on the chemical structure of amyloid proteins...
  42. ncbi request reprint Transthyretin amyloidosis in a patient of Iranian-Jewish extraction: a second Israeli-Jewish case
    Batia Kaplan
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Clin Chem Lab Med 45:625-8. 2007
    ..Since precise determination of the amyloid type has crucial therapeutic implications, we employed our new biochemical micro-techniques, together with molecular biology methods, to characterize the amyloid protein deposited...
  43. doi request reprint Free light chain monomer-dimer patterns in the diagnosis of multiple sclerosis
    Batia Kaplan
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    J Immunol Methods 390:74-80. 2013
    ..Our study highlights the role of the differential analysis of monomeric and dimeric κ- and λ-FLC for the precise diagnosis of MS...
  44. ncbi request reprint Charge differences between in vivo deposits in immunoglobulin light chain amyloidosis and non-amyloid light chain deposition disease
    Batia Kaplan
    The Heller Institute of Medical Research, Sheba Medical Centre, Tel Hashomer, Israel
    Br J Haematol 136:723-8. 2007
    ....
  45. ncbi request reprint New pieces in the puzzle of autoinflammatory disorders
    Nurit Tweezer-Zaks
    Department of Internal Medicine F, Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 6:103-6. 2004
  46. ncbi request reprint Intravenous colchicine for treatment of patients with familial Mediterranean fever unresponsive to oral colchicine
    Merav Lidar
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer 52621, Israel
    J Rheumatol 30:2620-3. 2003
    ..To evaluate the efficacy and safety of weekly intravenous (IV) colchicine, in addition to oral colchicine therapy, in a subset of patients with familial Mediterranean fever (FMF) unresponsive to oral colchicine prophylaxis...
  47. doi request reprint QT dispersion in uncomplicated familial Mediterranean fever
    Naomi Nussinovitch
    Hypertension Unit and Department of Internal Medicine D, Sheba Medical Center, Tel Hashomer, Israel
    Clin Rheumatol 29:1353-6. 2010
    ....
  48. doi request reprint Colchicine-free remission in familial Mediterranean fever: featuring a unique subset of the disease-a case control study
    Ilan Ben-Zvi
    Department of Medicine F and the Rheumatology unit, Sheba Medical Center, Tel Hashomer, Israel
    Orphanet J Rare Dis 9:3. 2014
    ..To demonstrate and clinically, genetically and demographically characterize familial Mediterranean fever (FMF) patients, maintaining remission despite colchicine abstinence...
  49. ncbi request reprint Large symptomatic pericardial effusion as the presentation of unrecognized cancer: a study in 173 consecutive patients undergoing pericardiocentesis
    Shomron Ben-Horin
    Department of Medicine, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Hashomer, Israel
    Medicine (Baltimore) 85:49-53. 2006
    ..This grave diagnosis cannot be ruled out on the basis of any clinical parameter. Thus, a more extensive workup should probably be considered in this patient group...
  50. ncbi request reprint Urine leukotriene B4 in familial Mediterranean fever and other forms of right lower abdominal pain
    Ariel G Bentancur
    Emergency Medicine Department, Sheba Medical Center, Tel Hashomer, Israel
    Acad Emerg Med 12:671-4. 2005
    ..Acute right lower abdominal pain may present a diagnostic dilemma. Leukotrienes have been found to be elevated in familial Mediterranean fever (FMF), a disease manifesting with recurrent episodes of "acute abdomen."..
  51. ncbi request reprint Serum amyloid A levels in kidney-transplanted patients with familial Mediterranean fever-amyloidosis
    Shaye Kivity
    Departments of Medicine A and C, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 13:202-5. 2011
    ..Since amyloidosis is prompted by high serum amyloid A (SAA) levels, increased SAA is expected to persist after transplantation. However, no data are available to confirm such an assumption...
  52. ncbi request reprint The structural effect of the E148Q MEFV mutation on the pyrin protein: a study using a quantum chemistry model
    Alexey Naimushin
    Leviev Heart Center, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 13:199-201. 2011
    ..The calculated change imposed by this mutation on pyrin structure may help to understand the role of this mutation...
  53. ncbi request reprint The contribution of genotypes at the MEFV and SAA1 loci to amyloidosis and disease severity in patients with familial Mediterranean fever
    Ruth Gershoni-Baruch
    Rambam Medical Center, Haifa, Israel
    Arthritis Rheum 48:1149-55. 2003
    ..In this study, we analyzed the contribution of genotypes at the MEFV and SAA1 loci to disease severity and to the development of amyloidosis, and further defined the factors affecting the clinical profile of FMF...
  54. ncbi request reprint The differential contribution of MEFV mutant alleles to the clinical profile of familial Mediterranean fever
    Ruth Gershoni-Baruch
    Institute of Human Genetics, Rambam Medical Center, Haifa, Israel
    Eur J Hum Genet 10:145-9. 2002
    ..These findings increase our understanding of the role of allelic variability in disease expression...
  55. ncbi request reprint Male sex coupled with articular manifestations cause a 4-fold increase in susceptibility to amyloidosis in patients with familial Mediterranean fever homozygous for the M694V-MEFV mutation
    Ruth Gershoni-Baruch
    Department of Human Genetics, Rambam Medical Center, Haifa, Israel
    J Rheumatol 30:308-12. 2003
    ..We investigated the role of sex as an independent contributor to the phenotypic profile in FMF and further defined the factors affecting disease expression and severity...
  56. ncbi request reprint [Clostridium difficile-associated diarrhea: causes and relationship to reactive arthritis]
    Alexey Naimushin
    Department of Medicine F, Sheba Medical Center, Tel Hashomer, Israel
    Harefuah 150:64-6. 2011
    ..It seems to be the first report of the association of MTX treatment with CDAD...
  57. ncbi request reprint Abdominal and digestive system associations of familial Mediterranean fever
    Adam Mor
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer 52621, Israel
    Am J Gastroenterol 98:2594-604. 2003
    ..This article will help the gastroenterologist to cope with most clinical situations related to the abdominal and alimentary tract in patients with FMF...
  58. ncbi request reprint A long-term follow-up after cardiac transplantation in a lupus patient: case report and review of the literature
    Nurit Tweezer-Zaks
    Rheumatology Unit, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Israel
    Ann N Y Acad Sci 1110:539-43. 2007
    ..In view of the limited experience with heart transplantation in these patients, we report the successful transplantation outcome in a lupus patient and review the literature in relation to graft and recipient conditions...
  59. doi request reprint Immunoglobulin free light chain dimers in human diseases
    Batia Kaplan
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    ScientificWorldJournal 11:726-35. 2011
    ..This review focuses on the disease-related changes of the structure and level of dimeric FLCs, and raises the questions regarding their formation, function, and role in the pathogenesis and diagnosis of human diseases...
  60. ncbi request reprint Colchicine in tear fluid of treated patients with familial Mediterranean fever
    Igal Leibovitch
    Department of Ophthalmology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel
    Cornea 22:191-3. 2003
    ....
  61. ncbi request reprint Colchicine inhibits heterotopic ossification: experimental study in rabbits
    Israel Dudkiewicz
    Department of Orthopedic Rehabilitation, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 7:31-4. 2005
    ..Heterotopic ossification is a common complication of hip surgery and musculoskeletal or brain trauma...
  62. ncbi request reprint Autoimmune phenomena following prostatectomy
    Nurit Tweezer-Zaks
    Departments of Medicine F, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 7:575-7. 2005
    ..There are no data on the association of prostatectomy with autoimmune phenomena in the English-language medical literature...
  63. doi request reprint Familial Mediterranean fever (FMF) with proteinuria: clinical features, histology, predictors, and prognosis in a cohort of 25 patients
    Olga Kukuy
    From the Institute of Nephrology and Hypertension, Sheba Medical Center, Tel Hashomer Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer Department of Pathology, Sheba Medical Center, Tel Hashomer Department of Pathology, Hadassah Hebrew University Medical Center, Jerusalem Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv The Dr Pinchas Borenstein Talpiot Medical Leadership Program 2012, Chaim Sheba Medical Center, Tel Hashomer, Israel
    J Rheumatol 40:2083-7. 2013
    ..Our aim was to determine the rate and underlying pathology of FMF-related nonamyloidotic proteinuria and compare its clinical course, demographic, and genetic features to those of FMF-amyloid nephropathy...
  64. ncbi request reprint Third International Conference on Familial Mediterranean Fever and Other Hereditary Inflammatory Disorders
    Pnina Langevitz
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Isr Med Assoc J 5:148-50. 2003
  65. ncbi request reprint Biochemical subtyping of amyloid in formalin-fixed tissue samples confirms and supplements immunohistologic data
    Batia Kaplan
    Department of Medicine, Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Am J Clin Pathol 121:794-800. 2004
    ....
  66. ncbi request reprint The composition of normal pericardial fluid and its implications for diagnosing pericardial effusions
    Shomron Ben-Horin
    Department of Medicine F, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Hashomer, Israel
    Am J Med 118:636-40. 2005
    ..Moreover, there is little data regarding the normal composition of the physiological pericardial fluid, which could serve as a reference for pathological effusions...
  67. ncbi request reprint [ECG changes during stroke]
    Shani Golan
    Department of Medicine F, Sheba Medical Center, Tel Hashomer, Israel
    Harefuah 147:568-9, 572. 2008
    ..The role of ECG changes in our patient and other patients with similar findings is yet to be determined...
  68. ncbi request reprint [Aspirin and endoscopy]
    Alexey Naimushin
    Medicine F, Sheba Medical Center, Tel Hashomer, Israel
    Harefuah 147:89-90, 92. 2008
    ..Such an approach may bridge the gap between the guidelines and the natural hesitation to perform minor endoscopic surgery under aspirin treatment...
  69. ncbi request reprint [Aortic atheroma and splenic emboli]
    Itan Ben-Zvi
    Department of Medicine F, Sheba Medical Center, Tel Hashomer, Israel
    Harefuah 149:279-82, 337, 336. 2010
    ....
  70. ncbi request reprint [Neurogenic pulmonary edema]
    Alexey Naimushin
    Department of Medicine F, Sheba Medical Center, Tel Hashomer, Israel
    Harefuah 147:169, 181. 2008
    ..It is treated conventionally, with diuretics and after-load reduction...
  71. ncbi request reprint [Takayasu's arteritis: new diagnostic tools and treatment]
    Asaf Achiron
    Medicine F, Sheba Medical Center, Tel Hashomer, Israel
    Harefuah 149:798-802, 810. 2010
    ..TA is more prevalent in Asia, affecting young adults. This review strives to increase awareness of TA clinical presentation, new diagnostic tools and modern therapeutic options...
  72. ncbi request reprint Thoracic and lung involvement in familial Mediterranean fever (FMF)
    Merav Lidar
    Heller Institute of Medical Research, Sheba Medical Center, Tel Hashomer, Israel
    Clin Chest Med 23:505-11. 2002
    ..Three patients had peritoneal mesothelioma, while one developed mesothelioma of the lung. Finally, thromboembolism should be considered, particularly in patients with FMF amyloidosis who present with respiratory distress...