Yechiel Levkovitz

Summary

Country: Israel

Publications

  1. ncbi request reprint Minocycline, a second-generation tetracycline, as a neuroprotective agent in an animal model of schizophrenia
    Yechiel Levkovitz
    The Emotion Cognition Research Center, The Shalvata Mental Health Care Center, P O B 94 Hod Hasharon, Israel
    Brain Res 1154:154-62. 2007
  2. ncbi request reprint Antidepressants induce cellular insulin resistance by activation of IRS-1 kinases
    Yechiel Levkovitz
    Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Rabin Campus, Petah Tiqva, Israel
    Mol Cell Neurosci 36:305-12. 2007
  3. doi request reprint A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia
    Yechiel Levkovitz
    The Emotion Cognition Research Center, The Shalvata Mental Health Care Center, P O B 94 Hod Hasharon, Israel
    J Clin Psychiatry 71:138-49. 2010
  4. ncbi request reprint Differential induction of apoptosis by antidepressants in glioma and neuroblastoma cell lines: evidence for p-c-Jun, cytochrome c, and caspase-3 involvement
    Yechiel Levkovitz
    Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Tel Aviv University, Rabin Campus, Petah Tiqva 49100, Israel
    J Mol Neurosci 27:29-42. 2005
  5. doi request reprint Deep transcranial magnetic stimulation add-on for treatment of negative symptoms and cognitive deficits of schizophrenia: a feasibility study
    Yechiel Levkovitz
    The Emotion Cognition Research Center, Shalvata Mental Health Care Center, Hod Hasharon, Israel, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Int J Neuropsychopharmacol 14:991-6. 2011
  6. ncbi request reprint Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors
    Irit Gil-Ad
    Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Campus Rabin, Petah Tiqva 49100, Israel, and Sackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel
    J Mol Neurosci 22:189-98. 2004
  7. ncbi request reprint Effect of L-tryptophan on memory in patients with schizophrenia
    Yechiel Levkovitz
    Shalvata Mental Health Center, Hod Hasharon, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Nerv Ment Dis 191:568-73. 2003
  8. ncbi request reprint Phenothiazines induce apoptosis in a B16 mouse melanoma cell line and attenuate in vivo melanoma tumor growth
    Irit Gil-Ad
    Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Rabin Medical Center Beilinson Campus, Petah Tiqva, Israel
    Oncol Rep 15:107-12. 2006
  9. doi request reprint Executive functioning among patients with borderline personality disorder (BPD) and their relatives
    Hila Z Gvirts
    The Emotion Cognition Research Center, Shalvata Mental Health Care Center, Hod Hasharon, Israel
    J Affect Disord 143:261-4. 2012
  10. doi request reprint H-coil repetitive transcranial magnetic stimulation for the treatment of bipolar depression: an add-on, safety and feasibility study
    Eiran Vadim Harel
    The Emotion Cognition Research Center, Shalvata Mental Health Care Center, Hod Hasharon, Israel
    World J Biol Psychiatry 12:119-26. 2011

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Minocycline, a second-generation tetracycline, as a neuroprotective agent in an animal model of schizophrenia
    Yechiel Levkovitz
    The Emotion Cognition Research Center, The Shalvata Mental Health Care Center, P O B 94 Hod Hasharon, Israel
    Brain Res 1154:154-62. 2007
    ..The discussion addresses potential mechanisms underlying the effects of minocycline and possible directions for future research...
  2. ncbi request reprint Antidepressants induce cellular insulin resistance by activation of IRS-1 kinases
    Yechiel Levkovitz
    Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Rabin Campus, Petah Tiqva, Israel
    Mol Cell Neurosci 36:305-12. 2007
    ..These results implicate selected SSRIs as inhibitors of insulin signaling and as potential inducers of cellular insulin resistance...
  3. doi request reprint A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia
    Yechiel Levkovitz
    The Emotion Cognition Research Center, The Shalvata Mental Health Care Center, P O B 94 Hod Hasharon, Israel
    J Clin Psychiatry 71:138-49. 2010
    ..Other proposed mechanisms of action include effects of minocycline on the dopaminergic system and its inhibition of microglial activation...
  4. ncbi request reprint Differential induction of apoptosis by antidepressants in glioma and neuroblastoma cell lines: evidence for p-c-Jun, cytochrome c, and caspase-3 involvement
    Yechiel Levkovitz
    Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Tel Aviv University, Rabin Campus, Petah Tiqva 49100, Israel
    J Mol Neurosci 27:29-42. 2005
    ..The high sensitivity to these drugs of the cancer cell, compared with primary brain tissue, suggests the potential use of these agents in the treatment of brain-derived tumors...
  5. doi request reprint Deep transcranial magnetic stimulation add-on for treatment of negative symptoms and cognitive deficits of schizophrenia: a feasibility study
    Yechiel Levkovitz
    The Emotion Cognition Research Center, Shalvata Mental Health Care Center, Hod Hasharon, Israel, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Int J Neuropsychopharmacol 14:991-6. 2011
    ..The effect of 20 daily deep-TMS sessions (20 Hz, 120% motor threshold) over the prefrontal cortex of 15 patients indicated improvement in cognition and negative symptoms that was maintained at 2-wk post-treatment follow-up...
  6. ncbi request reprint Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors
    Irit Gil-Ad
    Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Campus Rabin, Petah Tiqva 49100, Israel, and Sackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel
    J Mol Neurosci 22:189-98. 2004
    ..Overall, the marked apoptotic effect of phenothiazines in brain-derived cancer cells, and the low sensitivity of primary brain tissue suggest the potential use of selected agents as therapeutic modalities in brain cancer...
  7. ncbi request reprint Effect of L-tryptophan on memory in patients with schizophrenia
    Yechiel Levkovitz
    Shalvata Mental Health Center, Hod Hasharon, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Nerv Ment Dis 191:568-73. 2003
    ..These preliminary results suggest the possibility of using serotonin precursor to enhance memory function in schizophrenia...
  8. ncbi request reprint Phenothiazines induce apoptosis in a B16 mouse melanoma cell line and attenuate in vivo melanoma tumor growth
    Irit Gil-Ad
    Laboratory of Biological Psychiatry, Felsenstein Medical Research Center, Rabin Medical Center Beilinson Campus, Petah Tiqva, Israel
    Oncol Rep 15:107-12. 2006
    ..resulted in the reduction of lung tumor burden and an increase in mice survival. In conclusion, several phenothiazines, and particularly thioridazine, induced apoptosis of B16 melanoma cells and demonstrated in vivo anti-tumor activity...
  9. doi request reprint Executive functioning among patients with borderline personality disorder (BPD) and their relatives
    Hila Z Gvirts
    The Emotion Cognition Research Center, Shalvata Mental Health Care Center, Hod Hasharon, Israel
    J Affect Disord 143:261-4. 2012
    ..Thus, the aim of the present study was to investigate executive functions in both patients BPD and their unaffected first-degree relatives (parents)...
  10. doi request reprint H-coil repetitive transcranial magnetic stimulation for the treatment of bipolar depression: an add-on, safety and feasibility study
    Eiran Vadim Harel
    The Emotion Cognition Research Center, Shalvata Mental Health Care Center, Hod Hasharon, Israel
    World J Biol Psychiatry 12:119-26. 2011
    ..This pilot study evaluated the safety and feasibility of the H1-Coil as adjuvant treatment for bipolar depression (BPD)...
  11. ncbi request reprint H-coil repetitive transcranial magnetic stimulation for treatment resistant major depressive disorder: An 18-week continuation safety and feasibility study
    Eiran Vadim Harel
    The Emotion Cognition Research Center, Shalvata Mental Health Care Center, Hod Hasharon, Israel, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    World J Biol Psychiatry 15:298-306. 2014
    ..The current study examined the safety and feasibility of repetitive deep-TMS continuation treatment for MDD over the course of 18 weeks, following 4 weeks of acute treatment...
  12. doi request reprint Double dissociation between cognitive and affective empathy in borderline personality disorder
    Hagai Harari
    The Emotion Cognition Research Center, Shalvata Mental Health Care Center, Hod Hasharon, Israel
    Psychiatry Res 175:277-9. 2010
    ..These results suggest that a dysfunctional pattern of empathic capacity may account for behavioral difficulties in BPD...
  13. ncbi request reprint Ultimatum bargaining behavior of people affected by schizophrenia
    Nirit Agay
    The Raymond and Beverly Sackler Faculty of Exact Sciences, School of Mathematical Sciences, Tel Aviv University, Ramat Aviv, Israel
    Psychiatry Res 157:39-46. 2008
    ..In contrast, as Responders, schizophrenic patients acted not significantly different from controls. Further investigation is needed to establish the links between cognitive and symptomatic mediators and strategic decision-making ability...
  14. doi request reprint Repetitive transcranial magnetic stimulation in the treatment of depression in adolescents: an open-label study
    Yuval Bloch
    Shalvata Mental Health Center, Hod Hasharon, Israel
    J ECT 24:156-9. 2008
    ..This open-label pilot study examined repetitive transcranial magnetic stimulation as a possible treatment of adolescent resistant depression...
  15. ncbi request reprint Are psychotherapists consistent in their ethical attitude to patient confidentiality?
    Silvana Fennig
    The Schneider Children s Medical Center of Israel, Beilinson Campus, Petach Tikva, Israel
    Isr J Psychiatry Relat Sci 41:82-9. 2004
    ..The issue of confidentiality often causes an ethical dilemma for the psychotherapist...
  16. doi request reprint Understanding and knowledge of psychiatric treatment among adolescents and adults
    Ido Lurie
    Shalvata Mental Health Center, Shalvata Mental Health Center, Hod Hasharon, P O B 94, Israel
    Clin Child Psychol Psychiatry 14:589-94. 2009
    ..These data indicate that adolescents are no less knowledgeable than adults and should be regarded as competent partners in the process of therapeutic decision making...
  17. ncbi request reprint Suicidal behavior in minors-diagnostic differences between children and adolescents
    Ariel Ben-Yehuda
    The Emotion Cognition Research Center, Shalvata Mental Health Care Center, Hod Hasharon, Israel
    J Dev Behav Pediatr 33:542-7. 2012
    ..We hypothesized that suicidal behavior in children stems from a different diagnosis than suicidal behavior in adolescents, and thus merits its own investigation...
  18. ncbi request reprint Effectiveness and safety of adjunctive antidepressants in the treatment of bipolar depression: a review
    Eiran Vadim Harel
    Emotion Cognition Research Center, The Shalvata Mental Health Care Center, Hod Hasharon, Israel
    Isr J Psychiatry Relat Sci 45:121-8. 2008
    ....
  19. doi request reprint Assessment of negative symptoms and depression in schizophrenia: revision of the SANS and how it relates to the PANSS and CDSS
    Liron Rabany
    The Emotion Cognition Research Center, Shalvata Mental Health Center, Hod Hasharon, Israel
    Schizophr Res 126:226-30. 2011
    ..The current study revised SANS's structure and examined its correlations with the PANSS and the CDSS...
  20. ncbi request reprint Gender differences in electroconvulsive therapy: a retrospective chart review
    Yuval Bloch
    Shalvata Mental Health Center, Hod Hasharon, P O Box 94, Israel, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Affect Disord 84:99-102. 2005
    ..There is a growing interest in gender differences of different psychiatric disorders, especially major depression. We sought a possible gender difference related to electroconvulsive therapy (ECT)...
  21. ncbi request reprint Ethical dilemmas in psychotherapy: comparison between patients, therapists and laypersons
    Silvana Fennig
    Sackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel
    Isr J Psychiatry Relat Sci 42:251-7. 2005
    ..The attitudes of patients towards ethical dilemmas in psychotherapy have been reported in only a few studies...
  22. doi request reprint Lexical ambiguity resolution in Wernicke's area and its right homologue
    Yuval Harpaz
    Department of Psychology, Tel Aviv University, Tel Aviv, Israel
    Cortex 45:1097-103. 2009
    ....
  23. doi request reprint Executive functioning during full and partial remission (positive and negative symptomatic remission) of schizophrenia
    Yoram Braw
    Shalvata Mental Health Center, Hod Hasharon, Israel
    Schizophr Res 142:122-8. 2012
    ..The current study therefore examined the executive functioning of patients in full symptomatic remission and for the first time assessed two sub-groups of patients in partial remission...
  24. ncbi request reprint Reasons for referral for electroconvulsive therapy: a comparison between adolescents and adults
    Yuval Bloch
    Child and adolescent out patient clinic, Shalvata Mental Health Center, Hod Hasharon, Israel
    Australas Psychiatry 16:191-4. 2008
    ..In order to improve our understanding of the use of electroconvulsive therapy (ECT) in adolescent patients, we aimed to evaluate the reasons for referral for ECT in different age groups...
  25. ncbi request reprint The SSRIs drug Fluoxetine, but not the noradrenergic tricyclic drug Desipramine, improves memory performance during acute major depression
    Yechiel Levkovitz
    Shalvata Mental Health Center, Hod Hasharon, Israel
    Brain Res Bull 58:345-50. 2002
    ..Furthermore, in cases where, for various reasons, the treatment of choice is noradrenergic, it may be worthwhile to consider a supplementary serotonergic drug to improve memory deficits...
  26. ncbi request reprint Everyday memory and laboratory memory tests: general function predictors in schizophrenia and remitted depression
    Shumel Fennig
    Shalvata Mental Health Center, Sackler School of Medicine, Tel Aviv University Ramat Aviv, P O Box 94, Hod Hasharon, Israel, 45100
    J Nerv Ment Dis 190:677-82. 2002
    ..However, the advantages of these tests over laboratory memory tests need to be further investigated in larger and more representative samples...
  27. ncbi request reprint Learned irrelevance is disrupted in first-episode but not chronic schizophrenia patients
    Gilad Gal
    Shalvata Mental Health Center, Hod Hasharon, P O Box 94, Israel
    Behav Brain Res 159:267-75. 2005
    ..In addition to the LIrr paradigm the same subjects were tested in a covert-orientation task. No differences were observed between the groups on this task. The possible advantages of the new LIrr paradigm are discussed...
  28. ncbi request reprint Dissociation of cognitive from affective components of theory of mind in schizophrenia
    Simone G Shamay-Tsoory
    Department of Psychology and Brain and Behavior Center, University of Haifa, Haifa 31905, Israel
    Psychiatry Res 149:11-23. 2007
    ..These findings offer new insight into the affective facets of social behavior that may underlie the profound behavioral disturbances observed in schizophrenia...
  29. ncbi request reprint The neuroanatomical basis of affective mentalizing in schizophrenia: comparison of patients with schizophrenia and patients with localized prefrontal lesions
    Simone G Shamay-Tsoory
    Department of Psychology and Brain and Behavior Center, University of Haifa, Haifa, Israel
    Schizophr Res 90:274-83. 2007
    ....
  30. ncbi request reprint Neurocognitive basis of impaired empathy in schizophrenia
    Simone G Shamay-Tsoory
    Department of PsychologyUniversity of Haifa, Haifa, Israel
    Neuropsychology 21:431-8. 2007
    ..However, while cognitive empathy was particularly related to measurements of orbitofrontal (rather than dorsolateral) functioning, affective empathy was related to measures of social functioning...
  31. pmc Cognition in young schizophrenia outpatients: comparison of first-episode with multiepisode patients
    Yoram Braw
    Shalvata Mental Health Center, Hod Hasharon, 45100 Israel
    Schizophr Bull 34:544-54. 2008
    ..These findings can help clarify the course of cognitive decline in young-aged SZ patients and aid in the development of phase-appropriate interventions...
  32. ncbi request reprint A dominant negative Egr inhibitor blocks nerve growth factor-induced neurite outgrowth by suppressing c-Jun activation: role of an Egr/c-Jun complex
    Yechiel Levkovitz
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 22:3845-54. 2002
    ..Accordingly, our studies indicate that Egr and ZnEgr proteins regulate c-Jun activation via a novel mechanism, protein-protein interaction with c-Jun, rather than via their classical mode of action, binding to the ERE...