Research Topics
| Varda ShkapSummaryAffiliation: Kimron Veterinary Institute Country: Israel Publications
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Detail Information
Publications
Experimental transmission of field Anaplasma marginale and the A. centrale vaccine strain by Hyalomma excavatum, Rhipicephalus sanguineus and Rhipicephalus (Boophilus) annulatus ticksVarda Shkap
Division of Parasitology, Kimron Veterinary Institute, Bet Dagan 50250, Israel
Vet Microbiol 134:254-60. 2009..sanguineus, no transmission to susceptible cattle occurred during 3 months of observation, and anaplasmosis was not induced in splenectomized calves that were subinoculated with blood from calves on which R. sanguineus had fed...
Attenuated vaccines for tropical theileriosis, babesiosis and heartwater: the continuing necessityVarda Shkap
Division of Parasitology, Kimron Veterinary Institute, Bet Dagan, Israel
Trends Parasitol 23:420-6. 2007..As a result, there is a continuing necessity to use available live vaccines in tick and tick-borne disease-control strategies adapted to conditions prevailing in many parts of the world...
Babesia bigemina: attenuation of an Uzbek isolate for immunization of cattle with live calf- or culture-derived parasitesVarda Shkap
Kimron Veterinary Institute, P O Box 12, Bet Dagan 50250, Israel
Vet Parasitol 146:221-6. 2007..bigemina, as reported from various geographical regions, the Central Asian strain was attenuated similarly to those that form the basis of the existing live B. bigemina vaccines in other parts of the world...
Concomitant infection of cattle with the vaccine strain Anaplasma marginale ss centrale and field strains of A. marginaleVarda Shkap
Division of Parasitology, Kimron Veterinary Institute, Bet Dagan, Israel
Vet Microbiol 130:277-84. 2008..The present results confirmed our previous findings that cattle grazing in an anaplasmosis-endemic field were subject to concomitant infection with both the vaccine A. centrale and the field A. marginale strains...
Vaccination of older Bos taurus bulls against bovine babesiosisVarda Shkap
Division of Parasitology, Kimron Veterinary Institute, P O Box 12, Bet Dagan 50250, Israel
Vet Parasitol 129:235-42. 2005....
Vaccination of cattle against B. bovis infection with live attenuated parasites and non-viable immunogensLea Fish
Division of Parasitology, Kimron Veterinary Institute, Bet Dagan 50250, Israel
Vaccine 26:G29-33. 2008..Upon challenge with virulent live parasites all immunized calves were solidly protected, but only partial protective immunity was acquired by rRAP1 immunization...
Proteolytic enzyme activity and attenuation of virulence in Theileria annulata schizont-infected cellsVarda Shkap
Division of Parasitology, Kimron Veterinary Institute, P O Box 12, Bet Dagan 50250, Israel
Vet Parasitol 115:247-55. 2003..excavatum sporozoites. For a strain to be used for vaccine production, it appears that animal inoculation still remains the most reliable method to assess the degree of attenuation and protection...
Immunity against Boophilus annulatus induced by the Bm86 (Tick-GARD) vaccineEugene Pipano
Veterinary Services and Animal Health, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, POB 12, 50250 Bet Dagan, Israel
Exp Appl Acarol 29:141-9. 2003..bigemina-infected females did not. Since B. bigemina is transmitted exclusively by nymphal stages of Bo. annulatus these results support the observation that immunity induced by Bm86 affects the larval stage of this tick...
Neospora caninum: in vivo and in vitro treatment with artemisoneMonica L Mazuz
Division of Parasitology, Kimron Veterinary Institute, Bet Dagan 50250, Israel
Vet Parasitol 187:99-104. 2012..Most treated gerbils produced high specific antibody titer and were protected against a challenge. Overall, artemisone could be considered as a future drug for neosporosis...
Seroprevalence of Neospora spp. among asymptomatic horses, aborted mares and horses demonstrating neurological signs in IsraelEitan B Kligler
Koret School of Veterinary Medicine, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jeruslem, P O Box 12, Rehovot 76100, Israel
Vet Parasitol 148:109-13. 2007..antibodies performed on horses from the Middle East and the first to report significant difference in seropositivity between asymptomatic horses and horses exhibiting neurological signs...
Immunological relationship between Neospora caninum and Besnoitia besnoitiVarda Shkap
Division of Parasitology, The Kimron Veterinary Institute, P O Box 12, 50250 Bet Dagan, Israel
Vet Parasitol 106:35-43. 2002..caninum antigen was probed with B. besnoiti antiserum. Immunization and challenge experiments in the highly susceptible Mongolian gerbil (Meriones unguiculatus) showed essentially no cross-protection between N. caninum and B. besnoiti...
Expression of major surface protein 2 variants with conserved T-cell epitopes in Anaplasma centrale vaccinatesVarda Shkap
Department of Parasitology, Kimron Veterinary Institute, Bet Dagan, Israel
Infect Immun 70:642-8. 2002..centrale vaccine efficacy...
Monozoic cysts of Hepatozoon canisGad Baneth
School of Veterinary Medicine, Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
J Parasitol 89:379-81. 2003..The H. canis cyst stage differs in size and morphology from the large cysts of H. americanum, the second Hepatozoon species known to infect dogs...
Genetic diversity of anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine developmentJose De La Fuente
Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078 2007, USA
Anim Health Res Rev 6:75-89. 2005..Information concerning the genetic diversity of Anaplasma spp. MSPs will likely influence the development of serodiagnostic assays and vaccine strategies for the control of anaplasmosis...
Identification of midgut and salivary glands as specific and distinct barriers to efficient tick-borne transmission of Anaplasma marginaleMassaro W Ueti
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
Infect Immun 75:2959-64. 2007..These results establish that there are at least two specific barriers to efficient tick-borne transmission, the midgut and salivary glands, and highlight the complexity of the pathogen-tick interaction...
Bovine immune response to inoculation with Neospora caninum surface antigen SRS2 lipopeptides mimics immune response to infection with live parasitesTimothy V Baszler
Department of Veterinary Microbiology and Pathology, Bustad Hall, Washington State University, Pullman, WA 99164 7040, USA
Clin Vaccine Immunol 15:659-67. 2008..The findings support the investigation of NcSRS2 immunogens for protection against N. caninum-induced fetal infection and abortion in cattle...
Expression of Anaplasma marginale major surface protein 2 operon-associated proteins during mammalian and arthropod infectionCHRISTIANE V LOHR
Program in Vector Borne Diseases, Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington 99164 7040, USA
Infect Immun 70:6005-12. 2002....
Pan-Mediterranean comparison for the molecular detection of Theileria annulataOlivier A E Sparagano
School of Agriculture, Food and Rural Development, University of Newcastle, Newcastle upon Tyne NE1 7RU, UK
Ann N Y Acad Sci 969:73-7. 2002..4 to 91.3%. The overall mismatch between laboratories was around 30% by whatever technique used. This paper describes the methodological parameters that could explain the variation of results...
Phylogenetic analysis of the erythrocytic Anaplasma species based on 16S rDNA and GroEL (HSP60) sequences of A. marginale, A. centrale, and A. ovis and the specific detection of A. centrale vaccine strainAla E Lew
Department of Primary Industries, Agency for Food and Fibre Sciences, c o Animal Research Institute, 665 Fairfield Rd, Locked Mail Bag No 4, Yeerongpilly, Moorooka, Queensland 4105, Australia
Vet Microbiol 92:145-60. 2003..centrale vaccine (Theiler, 1911) specifically. This study confirms the suitability of 16S rDNA sequences to define genera and demonstrates the usefulness of GroEL sequences for defining species of erythrocytic Anaplasma...
Canine hepatozoonosis: two disease syndromes caused by separate Hepatozoon sppGad Baneth
School of Veterinary Medicine, Hebrew University, P.O. Box 12, Rehovot 76100, Israel
Trends Parasitol 19:27-31. 2003
Life cycle of Hepatozoon canis (Apicomplexa: Adeleorina: Hepatozoidae) in the tick Rhipicephalus sanguineus and domestic dog (Canis familiaris)Gad Baneth
School of Veterinary Medicine, Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
J Parasitol 93:283-99. 2007..Skeletal pain and recumbency were manifested in 2 dogs. This study further elucidates the life cycle of H. canis and provides a sequential morphologic description of H. canis merogony, gamontogony, and sporogony...
Infection with a proposed new subspecies of Babesia canis, Babesia canis subsp. presentii, in domestic catsGad Baneth
School of Veterinary Medicine, Hebrew University, Rehovot 76100, Israel
J Clin Microbiol 42:99-105. 2004..canis present in dogs, we propose to identify the novel feline genotype of B. canis described in the present study as a new subspecies, B. canis subsp. presentii...
Emergence of distinct genotypes of Cryptosporidium parvum in structured host populationsSultan Tanriverdi
Division of Infectious Diseases, Tufts Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA
Appl Environ Microbiol 72:2507-13. 2006..This may explain the frequent detection of host-specific genotypes with unknown taxonomic status in surface water and the existence of geographically restricted C. hominis genotypes in humans...
