Varda Shkap

Summary

Affiliation: Kimron Veterinary Institute
Country: Israel

Publications

  1. doi request reprint Experimental transmission of field Anaplasma marginale and the A. centrale vaccine strain by Hyalomma excavatum, Rhipicephalus sanguineus and Rhipicephalus (Boophilus) annulatus ticks
    Varda Shkap
    Division of Parasitology, Kimron Veterinary Institute, Bet Dagan 50250, Israel
    Vet Microbiol 134:254-60. 2009
  2. ncbi request reprint Babesia bigemina: attenuation of an Uzbek isolate for immunization of cattle with live calf- or culture-derived parasites
    Varda Shkap
    Kimron Veterinary Institute, P O Box 12, Bet Dagan 50250, Israel
    Vet Parasitol 146:221-6. 2007
  3. ncbi request reprint Attenuated vaccines for tropical theileriosis, babesiosis and heartwater: the continuing necessity
    Varda Shkap
    Division of Parasitology, Kimron Veterinary Institute, Bet Dagan, Israel
    Trends Parasitol 23:420-6. 2007
  4. doi request reprint Concomitant infection of cattle with the vaccine strain Anaplasma marginale ss centrale and field strains of A. marginale
    Varda Shkap
    Division of Parasitology, Kimron Veterinary Institute, Bet Dagan, Israel
    Vet Microbiol 130:277-84. 2008
  5. ncbi request reprint Vaccination of older Bos taurus bulls against bovine babesiosis
    Varda Shkap
    Division of Parasitology, Kimron Veterinary Institute, P O Box 12, Bet Dagan 50250, Israel
    Vet Parasitol 129:235-42. 2005
  6. doi request reprint Artemisone inhibits in vitro and in vivo propagation of Babesia bovis and B. bigemina parasites
    Monica L Mazuz
    Division of Parasitology, Kimron Veterinary Institute, 50250 Bet Dagan, Israel Electronic address
    Exp Parasitol 135:690-4. 2013
  7. doi request reprint Vaccination of cattle against B. bovis infection with live attenuated parasites and non-viable immunogens
    Lea Fish
    Division of Parasitology, Kimron Veterinary Institute, Bet Dagan 50250, Israel
    Vaccine 26:G29-33. 2008
  8. ncbi request reprint Proteolytic enzyme activity and attenuation of virulence in Theileria annulata schizont-infected cells
    Varda Shkap
    Division of Parasitology, Kimron Veterinary Institute, P O Box 12, Bet Dagan 50250, Israel
    Vet Parasitol 115:247-55. 2003
  9. ncbi request reprint Immunity against Boophilus annulatus induced by the Bm86 (Tick-GARD) vaccine
    Eugene Pipano
    Veterinary Services and Animal Health, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, POB 12, 50250 Bet Dagan, Israel
    Exp Appl Acarol 29:141-9. 2003
  10. doi request reprint Neospora caninum: in vivo and in vitro treatment with artemisone
    Monica L Mazuz
    Division of Parasitology, Kimron Veterinary Institute, Bet Dagan 50250, Israel
    Vet Parasitol 187:99-104. 2012

Collaborators

Detail Information

Publications24

  1. doi request reprint Experimental transmission of field Anaplasma marginale and the A. centrale vaccine strain by Hyalomma excavatum, Rhipicephalus sanguineus and Rhipicephalus (Boophilus) annulatus ticks
    Varda Shkap
    Division of Parasitology, Kimron Veterinary Institute, Bet Dagan 50250, Israel
    Vet Microbiol 134:254-60. 2009
    ..sanguineus, no transmission to susceptible cattle occurred during 3 months of observation, and anaplasmosis was not induced in splenectomized calves that were subinoculated with blood from calves on which R. sanguineus had fed...
  2. ncbi request reprint Babesia bigemina: attenuation of an Uzbek isolate for immunization of cattle with live calf- or culture-derived parasites
    Varda Shkap
    Kimron Veterinary Institute, P O Box 12, Bet Dagan 50250, Israel
    Vet Parasitol 146:221-6. 2007
    ..bigemina, as reported from various geographical regions, the Central Asian strain was attenuated similarly to those that form the basis of the existing live B. bigemina vaccines in other parts of the world...
  3. ncbi request reprint Attenuated vaccines for tropical theileriosis, babesiosis and heartwater: the continuing necessity
    Varda Shkap
    Division of Parasitology, Kimron Veterinary Institute, Bet Dagan, Israel
    Trends Parasitol 23:420-6. 2007
    ..As a result, there is a continuing necessity to use available live vaccines in tick and tick-borne disease-control strategies adapted to conditions prevailing in many parts of the world...
  4. doi request reprint Concomitant infection of cattle with the vaccine strain Anaplasma marginale ss centrale and field strains of A. marginale
    Varda Shkap
    Division of Parasitology, Kimron Veterinary Institute, Bet Dagan, Israel
    Vet Microbiol 130:277-84. 2008
    ..The present results confirmed our previous findings that cattle grazing in an anaplasmosis-endemic field were subject to concomitant infection with both the vaccine A. centrale and the field A. marginale strains...
  5. ncbi request reprint Vaccination of older Bos taurus bulls against bovine babesiosis
    Varda Shkap
    Division of Parasitology, Kimron Veterinary Institute, P O Box 12, Bet Dagan 50250, Israel
    Vet Parasitol 129:235-42. 2005
    ....
  6. doi request reprint Artemisone inhibits in vitro and in vivo propagation of Babesia bovis and B. bigemina parasites
    Monica L Mazuz
    Division of Parasitology, Kimron Veterinary Institute, 50250 Bet Dagan, Israel Electronic address
    Exp Parasitol 135:690-4. 2013
    ....
  7. doi request reprint Vaccination of cattle against B. bovis infection with live attenuated parasites and non-viable immunogens
    Lea Fish
    Division of Parasitology, Kimron Veterinary Institute, Bet Dagan 50250, Israel
    Vaccine 26:G29-33. 2008
    ..Upon challenge with virulent live parasites all immunized calves were solidly protected, but only partial protective immunity was acquired by rRAP1 immunization...
  8. ncbi request reprint Proteolytic enzyme activity and attenuation of virulence in Theileria annulata schizont-infected cells
    Varda Shkap
    Division of Parasitology, Kimron Veterinary Institute, P O Box 12, Bet Dagan 50250, Israel
    Vet Parasitol 115:247-55. 2003
    ..excavatum sporozoites. For a strain to be used for vaccine production, it appears that animal inoculation still remains the most reliable method to assess the degree of attenuation and protection...
  9. ncbi request reprint Immunity against Boophilus annulatus induced by the Bm86 (Tick-GARD) vaccine
    Eugene Pipano
    Veterinary Services and Animal Health, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, POB 12, 50250 Bet Dagan, Israel
    Exp Appl Acarol 29:141-9. 2003
    ..bigemina-infected females did not. Since B. bigemina is transmitted exclusively by nymphal stages of Bo. annulatus these results support the observation that immunity induced by Bm86 affects the larval stage of this tick...
  10. doi request reprint Neospora caninum: in vivo and in vitro treatment with artemisone
    Monica L Mazuz
    Division of Parasitology, Kimron Veterinary Institute, Bet Dagan 50250, Israel
    Vet Parasitol 187:99-104. 2012
    ..Most treated gerbils produced high specific antibody titer and were protected against a challenge. Overall, artemisone could be considered as a future drug for neosporosis...
  11. ncbi request reprint Seroprevalence of Neospora spp. among asymptomatic horses, aborted mares and horses demonstrating neurological signs in Israel
    Eitan B Kligler
    Koret School of Veterinary Medicine, Faculty of Agricultural, Food and Environmental Quality Sciences, The Hebrew University of Jeruslem, P O Box 12, Rehovot 76100, Israel
    Vet Parasitol 148:109-13. 2007
    ..antibodies performed on horses from the Middle East and the first to report significant difference in seropositivity between asymptomatic horses and horses exhibiting neurological signs...
  12. ncbi request reprint Monozoic cysts of Hepatozoon canis
    Gad Baneth
    School of Veterinary Medicine, Hebrew University of Jerusalem, P O Box 12, Rehovot 76100, Israel
    J Parasitol 89:379-81. 2003
    ..The H. canis cyst stage differs in size and morphology from the large cysts of H. americanum, the second Hepatozoon species known to infect dogs...
  13. ncbi request reprint Immunological relationship between Neospora caninum and Besnoitia besnoiti
    Varda Shkap
    Division of Parasitology, The Kimron Veterinary Institute, P O Box 12, 50250 Bet Dagan, Israel
    Vet Parasitol 106:35-43. 2002
    ..caninum antigen was probed with B. besnoiti antiserum. Immunization and challenge experiments in the highly susceptible Mongolian gerbil (Meriones unguiculatus) showed essentially no cross-protection between N. caninum and B. besnoiti...
  14. ncbi request reprint Canine hepatozoonosis: two disease syndromes caused by separate Hepatozoon spp
    Gad Baneth
    School of Veterinary Medicine, Hebrew University, P O Box 12, Rehovot 76100, Israel
    Trends Parasitol 19:27-31. 2003
  15. pmc Expression of major surface protein 2 variants with conserved T-cell epitopes in Anaplasma centrale vaccinates
    Varda Shkap
    Department of Parasitology, Kimron Veterinary Institute, Bet Dagan, Israel
    Infect Immun 70:642-8. 2002
    ..centrale vaccine efficacy...
  16. pmc Identification of midgut and salivary glands as specific and distinct barriers to efficient tick-borne transmission of Anaplasma marginale
    Massaro W Ueti
    Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
    Infect Immun 75:2959-64. 2007
    ..These results establish that there are at least two specific barriers to efficient tick-borne transmission, the midgut and salivary glands, and highlight the complexity of the pathogen-tick interaction...
  17. ncbi request reprint Genetic diversity of anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development
    Jose De La Fuente
    Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078 2007, USA
    Anim Health Res Rev 6:75-89. 2005
    ..Information concerning the genetic diversity of Anaplasma spp. MSPs will likely influence the development of serodiagnostic assays and vaccine strategies for the control of anaplasmosis...
  18. pmc Bovine immune response to inoculation with Neospora caninum surface antigen SRS2 lipopeptides mimics immune response to infection with live parasites
    Timothy V Baszler
    Department of Veterinary Microbiology and Pathology, Bustad Hall, Washington State University, Pullman, WA 99164 7040, USA
    Clin Vaccine Immunol 15:659-67. 2008
    ..The findings support the investigation of NcSRS2 immunogens for protection against N. caninum-induced fetal infection and abortion in cattle...
  19. pmc Expression of Anaplasma marginale major surface protein 2 operon-associated proteins during mammalian and arthropod infection
    CHRISTIANE V LOHR
    Program in Vector Borne Diseases, Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington 99164 7040, USA
    Infect Immun 70:6005-12. 2002
    ....
  20. ncbi request reprint Pan-Mediterranean comparison for the molecular detection of Theileria annulata
    Olivier A E Sparagano
    School of Agriculture, Food and Rural Development, University of Newcastle, Newcastle upon Tyne NE1 7RU, UK
    Ann N Y Acad Sci 969:73-7. 2002
    ..4 to 91.3%. The overall mismatch between laboratories was around 30% by whatever technique used. This paper describes the methodological parameters that could explain the variation of results...
  21. ncbi request reprint Phylogenetic analysis of the erythrocytic Anaplasma species based on 16S rDNA and GroEL (HSP60) sequences of A. marginale, A. centrale, and A. ovis and the specific detection of A. centrale vaccine strain
    Ala E Lew
    Department of Primary Industries, Agency for Food and Fibre Sciences, c o Animal Research Institute, 665 Fairfield Rd, Locked Mail Bag No 4, Yeerongpilly, Moorooka, Queensland 4105, Australia
    Vet Microbiol 92:145-60. 2003
    ..centrale vaccine (Theiler, 1911) specifically. This study confirms the suitability of 16S rDNA sequences to define genera and demonstrates the usefulness of GroEL sequences for defining species of erythrocytic Anaplasma...
  22. pmc Infection with a proposed new subspecies of Babesia canis, Babesia canis subsp. presentii, in domestic cats
    Gad Baneth
    School of Veterinary Medicine, Hebrew University, Rehovot 76100, Israel
    J Clin Microbiol 42:99-105. 2004
    ..canis present in dogs, we propose to identify the novel feline genotype of B. canis described in the present study as a new subspecies, B. canis subsp. presentii...
  23. ncbi request reprint Life cycle of Hepatozoon canis (Apicomplexa: Adeleorina: Hepatozoidae) in the tick Rhipicephalus sanguineus and domestic dog (Canis familiaris)
    Gad Baneth
    School of Veterinary Medicine, Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel
    J Parasitol 93:283-99. 2007
    ..Skeletal pain and recumbency were manifested in 2 dogs. This study further elucidates the life cycle of H. canis and provides a sequential morphologic description of H. canis merogony, gamontogony, and sporogony...
  24. pmc Emergence of distinct genotypes of Cryptosporidium parvum in structured host populations
    Sultan Tanriverdi
    Division of Infectious Diseases, Tufts Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA
    Appl Environ Microbiol 72:2507-13. 2006
    ..This may explain the frequent detection of host-specific genotypes with unknown taxonomic status in surface water and the existence of geographically restricted C. hominis genotypes in humans...