G Leitner

Summary

Affiliation: Kimron Veterinary Institute
Country: Israel

Publications

  1. ncbi Development of a Staphylococcus aureus vaccine against mastitis in dairy cows. II. Field trial
    Gabriel Leitner
    National Mastitis Reference Center, Bet Dagon, Israel
    Vet Immunol Immunopathol 93:153-8. 2003
  2. ncbi Changes in milk composition as affected by subclinical mastitis in goats
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Bet Dagan 50250, Israel
    J Dairy Sci 87:1719-26. 2004
  3. ncbi Changes in milk composition as affected by subclinical mastitis in sheep
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Bet Dagan 50250, Israel
    J Dairy Sci 87:46-52. 2004
  4. ncbi Staphylococcus aureus vaccine against mastitis in dairy cows, composition and evaluation of its immunogenicity in a mouse model
    G Leitner
    National Mastitis Reference Center, Ministry of Agriculture and Rural Development, PO Box 12, Bet Dagan 50250, Israel
    Vet Immunol Immunopathol 93:159-67. 2003
  5. ncbi Development of a Staphylococcus aureus vaccine against mastitis in dairy cows. I. Challenge trials
    Gabriel Leitner
    National Mastitis Reference Center, Ministry of Agriculture and Rural Development, P O B 12, Bet Dagan 50250, Israel
    Vet Immunol Immunopathol 93:31-8. 2003
  6. ncbi Staphylococcus aureus exosecretions and bovine mastitis
    A Younis
    National Mastitis Reference Center, Kimron Veterinary Institute, Dagan, Israel
    J Vet Med B Infect Dis Vet Public Health 50:1-7. 2003
  7. ncbi Pseudomonas aeruginosa mastitis outbreaks in sheep and goat flocks: antibody production and vaccination in a mouse model
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, P O Box 12, Bet Dagan 50250, Israel
    Vet Immunol Immunopathol 119:198-203. 2007
  8. ncbi Immune cell differentiation in mammary gland tissues and milk of cows chronically infected with Staphylococcus aureus
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, Bet Dagan, Israel
    J Vet Med B Infect Dis Vet Public Health 50:45-52. 2003
  9. ncbi Staphylococcus aureus strains isolated from bovine mastitis: virulence, antibody production and protection from challenge in a mouse model
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, P O Box 12, Bet Dagan 50250, Israel
    FEMS Immunol Med Microbiol 35:99-106. 2003
  10. doi Lipopolysaccharide challenge of the mammary gland in cows induces nitrosative stress that impairs milk oxidative stability
    N Silanikove
    Biology of Lactation Laboratory, Institute of Animal Science, The Volcani Center, P O Box 6, Bet Dagan 50250, Israel
    Animal 6:1451-9. 2012

Collaborators

  • Nissim Silanikove
  • A Arieli
  • Z Samra
  • S Sela
  • A Shamay
  • S Blum
  • J I Weller
  • O Krifucks
  • E D Heller
  • Ahmed Younis
  • Arthur Saran
  • Israel Yeruham
  • Eyal Klement
  • A Younis
  • Alon M Levy
  • O Hammer-Muntz
  • E Ezra
  • Shamuel Zamir
  • Natan Gollop
  • Tamir Goshen
  • Gideon Fleminger
  • Nahum Shpigel
  • Oleg Krifucks
  • Adin Shwimmer
  • Nirit Ilsar-Adiri
  • Shamuel Friedman
  • Adin Schwimmer
  • Elimelech D Heller
  • Shmuel Friedman
  • Marcelo Chaffer
  • A Saran
  • Shane C Burgess
  • Greg Underwood
  • Irit Davidson
  • A Glickman
  • E Dan Heller

Detail Information

Publications29

  1. ncbi Development of a Staphylococcus aureus vaccine against mastitis in dairy cows. II. Field trial
    Gabriel Leitner
    National Mastitis Reference Center, Bet Dagon, Israel
    Vet Immunol Immunopathol 93:153-8. 2003
    ..5 kg per day higher than the non-vaccinated control cows. These results suggest that the new vaccine elicits a non-specific health improvement of the udder in addition to specific protection against S. aureus...
  2. ncbi Changes in milk composition as affected by subclinical mastitis in goats
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Bet Dagan 50250, Israel
    J Dairy Sci 87:1719-26. 2004
    ..The Yc was significantly lower in the infected halves, and clotting time was significantly longer. The mechanisms of the effects of SM on milk yield and Yc in goats and sheep are discussed and compared...
  3. ncbi Changes in milk composition as affected by subclinical mastitis in sheep
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Bet Dagan 50250, Israel
    J Dairy Sci 87:46-52. 2004
    ..4 times as high in the infected glands than in the uninfected ones. Curd yield was significantly lower in the infected glands than in the uninfected ones...
  4. ncbi Staphylococcus aureus vaccine against mastitis in dairy cows, composition and evaluation of its immunogenicity in a mouse model
    G Leitner
    National Mastitis Reference Center, Ministry of Agriculture and Rural Development, PO Box 12, Bet Dagan 50250, Israel
    Vet Immunol Immunopathol 93:159-67. 2003
    ..aureus strains. The results obtained showed that this vaccine exhibits a broad spectrum of antigenic and immunogenic properties that protects mice from homologues and hetrologous S. aureus challenge...
  5. ncbi Development of a Staphylococcus aureus vaccine against mastitis in dairy cows. I. Challenge trials
    Gabriel Leitner
    National Mastitis Reference Center, Ministry of Agriculture and Rural Development, P O B 12, Bet Dagan 50250, Israel
    Vet Immunol Immunopathol 93:31-8. 2003
    ..Moreover, all quarters challenged in the vaccinated cows, regardless of whether they were successfully infected or not with S. aureus, exhibited very mild inflammatory reactions, identified by their low SCCs (<100,000)...
  6. ncbi Staphylococcus aureus exosecretions and bovine mastitis
    A Younis
    National Mastitis Reference Center, Kimron Veterinary Institute, Dagan, Israel
    J Vet Med B Infect Dis Vet Public Health 50:1-7. 2003
    ..An association was found between the combinations of expressed bands and the cow responses: the majority of the cases could be linked to the expression of bands B and C...
  7. ncbi Pseudomonas aeruginosa mastitis outbreaks in sheep and goat flocks: antibody production and vaccination in a mouse model
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, P O Box 12, Bet Dagan 50250, Israel
    Vet Immunol Immunopathol 119:198-203. 2007
    ..Immunization with a vaccine prepared from either of the subgroups protected mice only from the homologues but not from the heterologues, whereas the bivalent vaccine protected mice from both subgroups...
  8. ncbi Immune cell differentiation in mammary gland tissues and milk of cows chronically infected with Staphylococcus aureus
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, Bet Dagan, Israel
    J Vet Med B Infect Dis Vet Public Health 50:45-52. 2003
    ..Mo numbers were high in most of those infected quarters, and were localized around the connective tissue and within the AL...
  9. ncbi Staphylococcus aureus strains isolated from bovine mastitis: virulence, antibody production and protection from challenge in a mouse model
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, P O Box 12, Bet Dagan 50250, Israel
    FEMS Immunol Med Microbiol 35:99-106. 2003
    ..Our findings demonstrate that pre-exposure of mice to a low dose of certain S. aureus strains could provide protection and that the antibodies produced could have an important protective role...
  10. doi Lipopolysaccharide challenge of the mammary gland in cows induces nitrosative stress that impairs milk oxidative stability
    N Silanikove
    Biology of Lactation Laboratory, Institute of Animal Science, The Volcani Center, P O Box 6, Bet Dagan 50250, Israel
    Animal 6:1451-9. 2012
    ..Thus, development of an improved quality control methodology may be important for the production of high-quality milk...
  11. doi Real-time visual/near-infrared analysis of milk-clotting parameters for industrial applications
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, PO Box 12, Bet Dagan 50250, Israel
    Animal 6:1170-7. 2012
    ....
  12. doi The effect of caprine arthritis encephalitis virus infection on production in goats
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, P O Box 12, Bet Dagan 50250, Israel
    Vet J 183:328-31. 2010
    ..This finding could be attributed to lateral virus transmission from seropositive to seronegative kids because of lack of segregation within the flock...
  13. doi Identification of a bovine mastitis Escherichia coli subset
    S Blum
    National Mastitis Reference Center, Division of Bacteriology, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, Bet Dagan, Israel
    Vet Microbiol 132:135-48. 2008
    ..coli population; they seem better able to multiply in the udder medium and to evade the host cellular innate immune response, and are genetically distinct from most environmental strains...
  14. doi Concentrations of ganglioside type M1 and immunoglobulin G in colostrum are inversely related to bacterial infection at early lactation in cows
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, PO Box 12, Bet Dagan 50250, Israel
    J Dairy Sci 91:3337-42. 2008
    ..It is suggested that application of a wider range of measures that reflect the immune status would enable the identification of most cows prone to new IMI...
  15. ncbi Genetic analysis of persistency in the israeli holstein population by the multitrait animal model
    J I Weller
    Institute of Animal Sciences, ARO, The Volcani Center, Bet Dagan 50250, Israel
    J Dairy Sci 89:2738-46. 2006
    ..58. Persistency in the Israeli Holstein population was analyzed by the multitrait animal model. The genetic trend since 1985 for the multiparity index was 0.22% persistency/yr, even though there was no direct selection on persistency...
  16. doi Online evaluation of milk quality according to coagulation properties for its optimal distribution for industrial applications
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, PO Box 12, Bet Dagan 50250, Israel
    J Dairy Sci 94:2923-32. 2011
    ..The ability of the AfiLab to perform this task was validated online and statistically by calibration against laboratory testing procedures...
  17. ncbi The effect of apramycin on colonization of pathogenic Escherichia coli in the intestinal tract of chicks
    G Leitner
    Kimron Veterinary Institute, Bet Dagan, Israel
    Vet Q 23:62-6. 2001
    ..Taken together, our in vitro and in vivo results show that apramycin is effective against E. coli by preventing colonization of the gut by the bacteria, which could lead to a reduction of colibacillosis in poultry...
  18. ncbi Influence of Staphylococcus aureus exosecretions isolated from bovine mastitis on leukocyte activity in vitro
    G Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Ministry of Agriculture and Rural Development, Bet Dagan, Israel
    J Vet Med B Infect Dis Vet Public Health 49:354-60. 2002
    ..A few but not all of the exosecretions that activated the CD25 receptor on T-cells also activated the ACT3 receptor on CD4+ cells...
  19. ncbi Staphylococcus aureus leucocidin, a virulence factor in bovine mastitis
    Ahmed Younis
    National Mastitis Reference Center, Kimron Veterinary Institute, PO Box 12, Bet Dagan 50250, Israel
    J Dairy Res 72:188-94. 2005
    ..The results suggest that LukM/ LukF' induce inflammation into the udder by a mechanism similar to that of LPS or by a unique mechanism(s) which requires further investigation...
  20. ncbi Posttranslational ruling of xanthine oxidase activity in bovine milk by its substrates
    Nissim Silanikove
    Ruminant Physiology, Institute of Animal Science, Agricultural Research Organization, The Volcani Center, PO Box 6, Bet Dagan 50250, Israel
    Biochem Biophys Res Commun 363:561-5. 2007
    ..The specific response of XO to bacteria species and the resulting bacteria-dependent nitrosative stress further demonstrates that it is part of the gland immune system...
  21. ncbi Effect of subclinical intramammary infection on somatic cell counts, NAGase activity and gross composition of goats' milk
    Gabriel Leitner
    National Mastitis Reference Centre, Kimron Veterinary Institute, Israel
    J Dairy Res 71:311-5. 2004
    ..Milk composition (fat, protein and lactose) varied among flocks, with lower mean total protein in uninfected halves than in infected ones and higher lactose in uninfected than infected halves...
  22. doi Outbreak of subclinical mastitis in a flock of dairy goats associated with atypical Staphylococcus haemolyticus
    Gabriel Leitner
    National Mastitis Center, Kimron Veterinary Institute, Bet Dagan 50250, Israel
    J Dairy Res 76:1-5. 2009
    ..The outbreak caused by an atypical CNS underlines the need for accurate biochemical and genetic methods for ultimate identification of CNS to the species level...
  23. doi Hydrogen peroxide-dependent conversion of nitrite to nitrate as a crucial feature of bovine milk catalase
    Nissim Silanikove
    Biology of Lactation Laboratory, Institute of Animal Science, The Volcani Center, Bet Dagan 50250, Israel
    J Agric Food Chem 57:8018-25. 2009
    ..Recommendations for minimizing the deterioration in milk quality during commercial storage are presented...
  24. ncbi Phenotypic and genotypic characterization of Pseudomonas aeruginosa strains isolated from mastitis outbreaks in dairy herds
    Shlomo Sela
    Microbial Food Safety Research Unit, Department of Food Sciences, Agricultural Research Organization, The Volcani Center, PO Box 6, Bet Dagan 50250, Israel
    J Dairy Res 74:425-9. 2007
    ..The present study revealed that a large variety of Ps. aeruginosa strains may cause mastitis outbreaks in sheep, goat and cattle in Israel...
  25. ncbi Aetiology of intramammary infection and its effect on milk composition in goat flocks
    Gabriel Leitner
    National Mastitis Reference Center, Kimron Veterinary Institute, Bet Dagan 50250, Israel
    J Dairy Res 74:186-93. 2007
    ..A preventive treatment during the dry period should, therefore, be considered as an effective means of reducing the current rate of bacterial infections in goats...
  26. ncbi Role of xanthine oxidase, lactoperoxidase, and NO in the innate immune system of mammary secretion during active involution in dairy cows: manipulation with casein hydrolyzates
    Nissim Silanikove
    Ruminant Physiology, Institute of Animal Science, Agricultural Research Organization, The Volcani Center, P O Box 6, Bet Dagan 50250, Israel
    Free Radic Biol Med 38:1139-51. 2005
    ..The innate immune system play a major role in preventing intramammary infection during milk stasis and its activation may increase its effectiveness...
  27. ncbi Assessment of accuracy of disk diffusion tests for the determination of antimicrobial susceptibility of common bovine mastitis pathogens: a novel approach
    Eyal Klement
    The Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel
    Microb Drug Resist 11:342-50. 2005
    ..Thus, we suggest its adoption by microbiology diagnostic laboratories for the provision of accurate antimicrobial susceptibility results when using the disk diffusion test...
  28. ncbi Investigation and control of mastitis outbreaks caused by Pseudomonas aeruginosa in a sheep flock and a goat herd
    Israel Yeruham
    Hachaklait Gedera, The Hebrew University of Jerusalem, Rehovot, Israel
    Berl Munch Tierarztl Wochenschr 118:220-3. 2005
    ..Ruthless culling of all infected and carrier animals was an essential part of the control program against Pseudomonas aeruginosa mastitis...
  29. ncbi Interferon-containing supernatants increase Marek's disease herpesvirus genomes and gene transcription levels, but not virion replication in vitro
    Alon M Levy
    Hebrew University of Jerusalem, Faculty of Agriculture, Department of Animal Science, Rehovot, Israel
    Viral Immunol 16:501-9. 2003
    ..We propose MDV has evolved to increase specific gene transcription and genome copies per cell to compensate for ICS. We speculate that the bi-directional shared pp38/origin of replication promoter, is central to this mechanism...