Research Topics
Species | Dov HershkovitzSummaryCountry: Israel Publications
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Detail Information
Publications
Monogenic pigmentary skin disorders: genetics and pathophysiologyDov Hershkovitz
Center for Translational Genetics, Rappaport Institute for Research in the Medical Sciences, Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
Isr Med Assoc J 10:713-7. 2008..In the present review, we discuss normal skin pigmentation and the genetic underpinning of selected disorders of hypo- and hyperpigmentation...
Ondansetron for the prevention of seasickness in susceptible sailors: an evaluation at seaDov Hershkovitz
Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, Haifa, Israel
Aviat Space Environ Med 80:643-6. 2009..The purpose of the present study was to evaluate the 5HT3 blocker ondansetron in the prevention of seasickness...
Vestibular evoked myogenic potentials and saccular plasticity in diversHaim Lavon
Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, Israel Defense Forces Medical Corps, Haifa, Israel
Aviat Space Environ Med 81:103-6. 2010..The purpose of the present study was to examine possible changes in the sacculocollic reflex of professional divers and to investigate whether there might be diving-induced adaptation of the saccular response...
Vestibular evoked myogenic potential threshold and seasickness susceptibilityDror Tal
Motion Sickness and Human Performance Laboratory, Israel Naval Medical Institute, IDF Medical Corps, Haifa, Israel
J Vestib Res 16:273-8. 2006..Theoretically, increased susceptibility to seasickness may be due to a discrepancy between the various neural systems as a result of reduced otolith responses...
Development of a computerized morphometry application for assessment of the tumor fraction in colon carcinoma tissue samplesTova Hershkovitz
Department of Pediatrics B, B Rappaport Faculty of Medicine, Haifa, Israel
Appl Immunohistochem Mol Morphol 21:54-8. 2013..In conclusion, we believe that this program can be used for standardizing the evaluation of the tumor cell fraction in colon carcinoma and that its use might aid in making better diagnosis and treatment choices for these patients...
Novel mutations in GALNT3 causing hyperphosphatemic familial tumoral calcinosisAlan Yancovitch
Center for Translational Genetics, Rappaport Institute for Research in the Medical Sciences, Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
J Bone Miner Metab 29:621-5. 2011..Our data expand the spectrum of known mutations in GALNT3 and contribute to a better understanding of the phenotypic manifestations of mutations in this gene...
Disadhesion of epidermal keratinocytes: a histologic clue to palmoplantar keratodermas caused by DSG1 mutationsReuven Bergman
Department of Dermatology, Rambam Medical Center, Haifa, Israel
J Am Acad Dermatol 62:107-13. 2010..Recent developments in molecular genetics may lead to re-examination of the histopathology of inherited palmoplantar keratodermas (PPKs) based on more precise groupings of the various entities and syndromes...
A novel mutation in RASA1 causes capillary malformation and limb enlargementDov Hershkovitz
Department of Dermatology and Laboratory of Molecular Dermatology, Rambam Health Care Campus, Haifa, Israel
Arch Dermatol Res 300:385-8. 2008..A novel mutation in RASA1 was found to underlie the disease in this case. The present results illustrate the extensive degree of phenotypic heterogeneity associated with deleterious mutations in RASA1...
Functional characterization of SAMD9, a protein deficient in normophosphatemic familial tumoral calcinosisDov Hershkovitz
Institute of Pathology, Rambam Health Care Campus, Haifa, Israel
J Invest Dermatol 131:662-9. 2011..In conclusion, our data indicate that SAMD9, an IFN-γ-responsive protein, interacts with RGL2 to diminish the expression of EGR1, a protein of direct relevance to the pathogenesis of ectopic calcification and inflammation...
LNA-based PCR clamping enrichment assay for the identification of KRAS mutationsEdna Efrati
Center for Translational Genetics, B Rappaport Institute for Research in the Medical Sciences, Technion Israel Institute of Technology and Rambam Health Care Campus, Haifa, Israel
Cancer Biomark 8:89-94. 2010..In the present study, we developed a KRAS mutations detection method that is both simple and sensitive...
