Research Topics
| Tamir Ben-HurSummaryAffiliation: Hadassah University Hospital Country: Israel Publications
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Detail Information
Publications
Involvement of brain cytokines in the neurobehavioral disturbances induced by HIV-1 glycoprotein120Ohr Barak
Department of Psychology, The Hebrew University of Jerusalem, Mount Scopus, Jerusalem, 91905, Israel
Brain Res 933:98-108. 2002....
Stem cell therapy for myelin diseasesTamir Ben-Hur
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Curr Drug Targets 6:3-19. 2005....
Acute effects of purified and UV-inactivated Herpes simplex virus type 1 on the hypothalamo-pituitary-adrenocortical axisT Ben-Hur
Department of Neurology, Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University, Jerusalem, Israel
Neuroendocrinology 74:160-6. 2001....
Prospects of cell therapy for disorders of myelinTamir Ben-Hur
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Hospital, Jerusalem, Israel
Ann N Y Acad Sci 1142:218-49. 2008..In this review we consider the potential application of cell-based therapeutic strategies to disorders of myelin, highlighting the promises as well as the problems and potential perils of this treatment approach...
Immunization with a nonpathogenic HSV-1 strain prevents clinical and neuroendocrine changes of experimental HSV-1 encephalitisTamir Ben-Hur
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Hospital, P O Box 12, 000, Jerusalem 91120, Israel
J Neuroimmunol 152:5-10. 2004..Mortality was completely prevented. These results indicate that immunization with HSV-1 strain R-15 protects rats from lethal HSV-1 encephalitis and prevents its clinical and neurochemical manifestations...
Role of the central amygdala in modulating the pituitary-adrenocortical and clinical responses in experimental herpes simplex virus-1 encephalitisJoseph Weidenfeld
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Hospital, Jerusalem, Israel
Neuroendocrinology 81:267-72. 2005..These responses were also attenuated in rats with cAMG lesions. The cAMG plays an important role in mediating the neuroendocrine, febrile and behavioral responses to HSV-1 infection...
Effects of proinflammatory cytokines on the growth, fate, and motility of multipotential neural precursor cellsTamir Ben-Hur
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Hospital, Jerusalem, Israel
Mol Cell Neurosci 24:623-31. 2003..TNFalpha and IFNgamma increased outward migration of cells from spheres in vitro. Thus, TNFalpha and IFNgamma, key players in MS and EAE, inhibit NPC proliferation and induce their migration...
Reconstructing neural circuits using transplanted neural stem cells in the injured spinal cordTamir Ben-Hur
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical School, Jerusalem, Israel
J Clin Invest 120:3096-8. 2010....
Human embryonic stem cells for neuronal repairTamir Ben-Hur
Department of Neurology, Center for Human Neurogenetics, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Isr Med Assoc J 8:122-6. 2006....
Cell therapy for multiple sclerosisTamir Ben-Hur
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Hospital, Jerusalem 91120, Israel
Neurotherapeutics 8:625-42. 2011..An initial clinical trial has established the probable safety of their intravenous and intrathecal delivery. Short-term follow-up observed immunomodulatory effects and clinical benefit justifying further clinical trials...
Cytokine-mediated modulation of MMPs and TIMPs in multipotential neural precursor cellsTamir Ben-Hur
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical Center, Jerusalem, Israel
J Neuroimmunol 175:12-8. 2006..IFN-beta, on the other hand, appears to have an anti-proteolytic influence that may attenuate such NPC-mediated repair processes...
Transplanted multipotential neural precursor cells migrate into the inflamed white matter in response to experimental autoimmune encephalomyelitisTamir Ben-Hur
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Hospital, Jerusalem, Israel
Glia 41:73-80. 2003..Thus, the inflammatory process may attract targeted migration of transplanted precursor cells into the brain parenchyma...
Immunomodulation by neural stem cellsTamir Ben-Hur
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah University Hospital, Jerusalem, Israel
J Neurol Sci 265:102-4. 2008..In conclusion, neural precursor cells exert an immunomodulatory effect that inhibits CNS inflammation. Cell therapy in MS should be optimized to utilize both regenerative and immunologic properties of the cells...
A novel permissive role for glucocorticoids in induction of febrile and behavioral signs of experimental herpes simplex virus encephalitisT Ben-Hur
Department of Neurology, Hadassah Hebrew University Hospital, Jerusalem, Israel
Neuroscience 108:119-27. 2001..Circulating glucocorticoids play an essential permissive role in the induction of these host brain responses...
Transplanted neural precursor cells reduce brain inflammation to attenuate chronic experimental autoimmune encephalomyelitisOfira Einstein
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah--Hebrew University Hospital, Jerusalem, Israel
Exp Neurol 198:275-84. 2006..We suggest that the beneficial effect of transplanted NPCs in chronic EAE is mediated, in part, by decreasing brain inflammation and reducing tissue injury...
Conserved fate and function of ferumoxides-labeled neural precursor cells in vitro and in vivoMikhal E Cohen
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah University Medical Center, Jerusalem, Israel
J Neurosci Res 88:936-44. 2010..These results demonstrate that ferumoxides-based MRI cell tracking is well suited for non-invasive monitoring of NPC transplantation...
Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosisDimitrios Karussis
Department of Neurology, Hadassah Hebrew University Hospital, Ein Karem, Jerusalem IL 91120, Israel
Arch Neurol 67:1187-94. 2010....
Survival of neural precursor cells in growth factor-poor environment: implications for transplantation in chronic diseaseOfira Einstein
Department of Neurology, Agnes Ginges Center for Human Neurogenetics, Hadassah-Hebrew University Medical Center, Jerusalem 91120, Israel
Glia 53:449-55. 2006....
Neural precursor cells inhibit multiple inflammatory signalsNina Fainstein
Department of Neurology, The Agnes Ginges Center of Human Neurogenetics, Hadassah Hebrew University Medical Center, EinKerem, Jerusalem, Israel
Mol Cell Neurosci 39:335-41. 2008..In conclusion, NPCs ameliorate TCR-mediated T cell activation and inhibit inflammatory cytokines' signaling in immune cells. These findings may underlie the broad anti-inflammatory effects of NPCs in vivo...
Intraventricular transplantation of neural precursor cell spheres attenuates acute experimental allergic encephalomyelitisOfira Einstein
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah-Hebrew University Hospital, Jerusalem, Israel
Mol Cell Neurosci 24:1074-82. 2003..Thus, transplanted NPCs attenuate acute EAE via an anti-inflammatory mechanism which depends on cell ability to migrate into inflamed brain tissue...
Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian ratsTamir Ben-Hur
Department of Neurology, Agnes Ginges Center for Human Neurogenetics, Jerusalem, Israel
Stem Cells 22:1246-55. 2004..Our observations encourage further developments for the potential use of hESCs in the treatment of Parkinson's disease...
The changing face of neural stem cell therapy in neurologic diseasesOfira Einstein
Department of Neurology, Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical Center, Ein Kerem, Jerusalem, Israel
Arch Neurol 65:452-6. 2008..Herein, we review recent developments and future prospects of NSC therapy in neurologic diseases...
Transplanted neural precursors enhance host brain-derived myelin regenerationOfira Einstein
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel
J Neurosci 29:15694-702. 2009..In conclusion, NPC transplantation enhances host-derived myelin regeneration following chronic demyelination. This trophic effect may stimulate resident OPCs to overcome the remyelination failure in multiple sclerosis...
Retinal incorporation and differentiation of neural precursors derived from human embryonic stem cellsEyal Banin
Department of Ophthalmology, The Hadassah Human Embryonic Stem Cell Research Center, The Goldyne Savad Institute of Gene Therapy, Hadassah University Hospital, P.O. Box 12, 000, Ein-Kerem, Jerusalem 91120, Israel
Stem Cells 24:246-57. 2006..This may be the first step toward further developments that eventually may allow the use of hESCs for transplantation in retinal degenerations...
Neuroprotection and immunomodulation with mesenchymal stem cells in chronic experimental autoimmune encephalomyelitisIbrahim Kassis
Department of Neurology and Agnes Ginges Center for Neurogenetics, Jerusalem, Israel
Arch Neurol 65:753-61. 2008..To investigate the therapeutic potential of mesenchymal stromal cells (MSCs) in the chronic model of experimental autoimmune encephalomyelitis (EAE)...
Intraarterial multi-modal reperfusion therapy for acute ischemic stroke: a10 year single-center experienceRoni Eichel
Department of Neurology, Center for Neurogenetics and Cerebrovascular Research Laboratory, Hadassah University Hospital and Hebrew University Hadassah Medical School, Jerusalem, Israel
Isr Med Assoc J 14:479-83. 2012..Only 0.5% of stroke patients in Israel are treated with endovascular multi-modal reperfusion therapy (MMRT) each year...
Neuroprotective effect of transplanted human embryonic stem cell-derived neural precursors in an animal model of multiple sclerosisMichal Aharonowiz
The Hadassah Human Embryonic Stem Cells Research Center, The Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Medical Center, Jerusalem, Israel
PLoS ONE 3:e3145. 2008..A potential new therapeutic approach for MS is cell transplantation which may promote remyelination and suppress the inflammatory process...
Glucocorticoid resistance following herpes simplex-1 infection: role of hippocampal glucocorticoid receptorsDafna Bener
Department of Neurology, Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical School, Jerusalem, Israel
Neuroendocrinology 85:207-15. 2007..The results suggest that HSV-1 induced GC resistance may be mediated by downregulation of GC receptors in hippocampal tissue. These results may clarify a mechanism responsible for GC resistance following immune challenges...
Recanalization of symptomatic carotid artery dissections causing occlusion with multiple stents: the use of delayed double-contrast road mapJose E Cohen
Department of Neurosurgery, Hadassah University Medical Center, Jerusalem, Israel
Neurol Res 32:293-6. 2010..Spontaneous ICAD causing occlusion successfully recanalized with multiple telescoped stents extending intracranially has only been reported exceptionally...
Manganese-enhanced MRI in a rat model of Parkinson's diseaseGalit Pelled
MRI MRS Laboratory, Human Biology Research Center, Department of Medical Biophysics and Nuclear Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
J Magn Reson Imaging 26:863-70. 2007..To measure intra- and inter-hemispheric connectivity within the basal ganglia (BG) nuclei in healthy and in unilateral 6-hydroxydopamine (6-OHDA) Parkinson disease rat model in order to test the BG interhemispheric connectivity hypothesis...
Neural precursors attenuate autoimmune encephalomyelitis by peripheral immunosuppressionOfira Einstein
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Ann Neurol 61:209-18. 2007..Although stem cell therapy was introduced initially for cell replacement, we examine here whether NPCs possess immunomodulatory effects...
Intrahippocampal transplantation of transgenic neural precursor cells overexpressing interleukin-1 receptor antagonist blocks chronic isolation-induced impairment in memory and neurogenesisOfra Ben Menachem-Zidon
Department of Psychology, The Hebrew University of Jerusalem, Department of Neurology, Hadassah Hebrew University Hospital, Jerusalem, Israel
Neuropsychopharmacology 33:2251-62. 2008....
The use of telescoped flow diverters as an endovascular bypass in the management of symptomatic chronic carotid occlusionJose E Cohen
Department of Neurosurgery, Hadassah Hebrew University Medical Center, P O Box 12000, Jerusalem 91120, Israel
J Clin Neurosci 19:1026-8. 2012..The optimal application of these devices will continue to be defined as clinical experience evolves...
Myasthenia gravis-associated neuromyelitis optica-like disease: an immunological link between the central nervous system and muscle?Adi Vaknin-Dembinsky
Department of Neurology, Multiple Sclerosis Center and Immunobiology Research Laboratory, Hadassah University Hospital, Ein Kerem, PO Box 12000, Jerusalem 91120, Israel
Arch Neurol 68:1557-61. 2011..Aquaporin 4 (AQP4), the target autoantigen in neuromyelitis optica, is expressed both in the CNS and in the neuromuscular junction...
Time limited immunomodulatory functions of transplanted neural precursor cellsNina Fainstein
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical Center Jerusalem, Israel
Glia 61:140-9. 2013..Thus, the immunomodulatory effects of neural precursor cell transplantation are limited in time...
The effect of herpes simplex virus-1 on nitric oxide synthase in the rat brain: the role of glucocorticoidsJoseph Hasson
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah University Hospital, Jerusalem, Israel
Neuroimmunomodulation 18:111-6. 2011..The effect of glucocorticoids (GCs) on NOS responses to HSV-1 was also determined...
Gliomas display a microRNA expression profile reminiscent of neural precursor cellsIris Lavon
Department of Neurology, Hadassah Hebrew University Medical Centre, Leslie and Michael Gaffin Centre for Neuro Oncology, Jerusalem, Israel
Neuro Oncol 12:422-33. 2010..Furthermore, careful study of the 15 miRNAs that differ in expression between SCs and gliomas, particularly those 5 that are not SC-specific, may enhance our understanding of gliomagenesis...
A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristicsHanna Rosenmann
The Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah University Medical Center, Jerusalem, Israel
Exp Neurol 212:71-84. 2008....
Increased neuronal α-synuclein pathology associates with its accumulation in oligodendrocytes in mice modeling α-synucleinopathiesHaya Kisos
Biochemistry and Molecular Biology, IMRIC, The Hebrew University Hadassah Medical School, Jerusalem, Israel
PLoS ONE 7:e46817. 2012..Hence, pathogenic mechanisms leading to elevated levels of α-Syn in neurons underlie neuronal secretion and subsequent uptake of α-Syn by oligodendrocytes in MSA...
Rehabilitation outcomes of stroke patients treated with tissue plasminogen activatorZeev Meiner
Department of Physical Medicine, POB 24035, Hadassah Hebrew University Medical Center, Jerusalem, 91240 Israel
PM R 2:698-702; quiz 792. 2010..To investigate the influence of thrombolysis on functional outcomes after rehabilitation...
Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta productionYehuda Pollak
Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel
Ann Neurol 57:741-5. 2005..These findings demonstrate that cholinergic enhancement produces central and peripheral antiinflammatory effects and suggest a novel therapeutic mechanism for acetylcholinesterase inhibitors...
Decompressive hemicraniectomy improves outcome in patients with failed arterial recanalization after acute carotid artery occlusionDavid Arkadir
Department of Neurology, Hebrew University Hadassah Medical Center, Jerusalem, Israel
Neurol Res 32:1077-82. 2010..Decompressive hemicraniectomy reduces morbidity and mortality in patients with large hemispheric stroke. However, its role in patients that underwent failed endovascular reperfusion remains unknown...
Reversal of heroin neurobehavioral teratogenicity by grafting of neural progenitorsSophia Katz
The Ross Laboratory for Studies in Neural Birth Defects, Department of Anatomy and Cell Biology, The Hebrew University Hadassah Medical School, Jerusalem, Israel
J Neurochem 104:38-49. 2008..Neural progenitor grafting thus offers an animal model for reversing neurobehavioral deficits originating in septohippocampal cholinergic defects elicited by pre-natal exposure to insults...
Demyelination affects temporal aspects of perception: an optic neuritis studyNoa Raz
The Agnes Ginges Center for Human Neurogenetics, Laboratory for Neuroimmunology, The Department of Neurology, Jerusalem, Israel
Ann Neurol 71:531-8. 2012..We hypothesized that dynamic visual processes, such as motion perception, may be more vulnerable to slowed conduction in the optic nerve, and consequently be better associated with projection rates...
Prior use of angiotensin-converting enzyme inhibitors does not affect outcome in patients with intracerebral hemorrhageRoni Eichel
Cerebrovascular Service and the Periz and Chantel Sheinberg Cerebrovascular Research Laboratory, Department of Neurology, Hadassah Hebrew University Medical Center, Israel
Neurol Res 32:905-9. 2010..Angiotensin-converting enzyme inhibitors (ACEI) exert protective effects in patients with stroke but their effects remain unknown in patients with intracerebral hemorrhage (ICH)...
Stable genetic modification of human embryonic stem cells by lentiviral vectorsMichal Gropp
The Goldyne Savad Institute of Gene Therapy, Agnes Ginges Center for Human Neurogenetics, Hadassah University Hospital, 91120 Jerusalem, Israel
Mol Ther 7:281-7. 2003..Genetic modification of hES cells by lentiviral vectors provides a powerful tool for basic and applied research in the area of human ES cells...
Misleading one detail: a preventable mode of diagnostic error?Shahar Arzy
Department of Neurology, Hadassah Hebrew University Hospital, Jerusalem, Israel
J Eval Clin Pract 15:804-6. 2009..The presence of a single misleading detail may lead clinicians down a cognitive and actual path toward an incorrect diagnosis...
Natural course and pathogenesis of transient focal neurologic symptoms during pregnancyAnatoly Liberman
Department of Neurology, Hebrew University Hadassah Medical Center, Hadassah Ein Kerem, Jerusalem, Israel
Arch Neurol 65:218-20. 2008..To determine the pathogenesis and course of transient focal neurologic symptoms in pregnant women and to identify prognostic variables that will enable targeted workup...
The thyroid hormone, triiodothyronine, enhances fluoxetine-induced neurogenesis in rats: possible role in antidepressant-augmenting propertiesRenana Eitan
Biological Psychiatry Laboratory, Department of Psychiatry, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Int J Neuropsychopharmacol 13:553-61. 2010....
Reduced basal activity and increased functional homogeneity in sensorimotor and striatum of a Parkinson's disease rat model: a functional MRI studyGalit Pelled
MRI/MRS Lab, the Human Biology Research Center, Department of Medical Biophysics, Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Eur J Neurosci 21:2227-32. 2005....
Category specific dysnomia after thalamic infarction: a case-control studyNetta Levin
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Hospital, Jerusalem, Israel
Neuropsychologia 43:1385-90. 2005..This might reflect the role of the thalamus not only as a relay station but further as a central integrator of different stages of perceptual and semantic processing...
Novel therapies for acute ischemic strokeRonen R Leker
Department of Neurology, Ginges Center for Neurogenetics, Scheinberg Cerebrovascular Research Laboratory, Hadassah University Hospital, Hebrew University Hadassah Medical School, Jerusalem, Israel
Isr Med Assoc J 8:788-92. 2006..The current situation calls for novel therapeutic strategies to be used in acute ischemic stroke. This review surveys some of these novel and promising cutting edge therapies...
Susac syndromeMenachem Gross
Department of Otolaryngology Head and Neck Surgery, Hadassah Hebrew University Hospital, Jerusalem, Israel
Otol Neurotol 25:470-3. 2004..The objective of this study was to describe the clinical manifestations; radiographic, audiometric, and retinal fluorescein angiography findings; pathogenesis and treatment of Susac syndrome with review of the literature...
Hypnotic relaxation vs amitriptyline for tension-type headache: let the patient chooseYacov Ezra
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah University Medical Center, Jerusalem, Israel
Headache 52:785-91. 2012....
Patterns of misdiagnosis of multiple sclerosisNetta Levin
Department of Neurology, Agnes Ginges Center for Human Neurogenetics, Hadassah University Hospital, Jerusalem, Israel
Isr Med Assoc J 5:489-90. 2003..The difference in type of misdiagnosis between men and women may reflect a gender-dependent bias in the way physicians interpret sensory complaints...
Limbic encephalitis presenting as a post-partum psychiatric conditionMarc Gotkine
Department of Neurology, Hadassah University Hospital, Hebrew University Hadassah Medical School, Jerusalem, Israel
J Neurol Sci 308:152-4. 2011..These antibodies are found in many non-paraneoplastic patients with LE. Although antibody-mediated conditions tend to present or relapse post-partum, VGKC-LE in the post-partum period has not been described...
Endovascular stent-assisted angioplasty in the management of traumatic internal carotid artery dissectionsJose E Cohen
Department of Neurosurgery, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Stroke 36:e45-7. 2005..The prognosis of traumatic dissection of the internal carotid artery is worse than for spontaneous dissections. Rapid stenting followed by antiplatelet therapy may prevent complications when anticoagulation therapy is not applicable...
Induced neuroprotection independently from PrPSc accumulation in a mouse model for prion disease treated with simvastatinYaron Haviv
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah University Hospital, Jerusalem, Israel
Arch Neurol 65:762-75. 2008..Previous in vitro studies suggest that cholesterol-lowering drugs inhibit the conversion of PrP(C) to PrP(Sc) and the accumulation of the latter, possibly through the disturbance of cholesterol-rich membrane domains (lipid rafts)...
Extrathymic malignancies in patients with myasthenia gravisNetta Levin
Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah-Hebrew University Hospital, Jerusalem 91120, Israel
J Neurol Sci 237:39-43. 2005..Although MG is not a paraneoplastic phenomenon of extrathymic malignancy, the association between MG and malignancy may be due to a common background of immune dysregulation...
Intracerebral HIV-1 glycoprotein 120 produces sickness behavior and pituitary-adrenal activation in rats: role of prostaglandinsOhr Barak
Department of Psychology, The Hebrew University of Jerusalem, Mount Scopus, Jerusalem 91905, Israel
Brain Behav Immun 16:720-35. 2002..Prostaglandins are important mediators of the physiological, but not the behavioral effects of brain gp120...
A dual role for interleukin-1 in hippocampal-dependent memory processesInbal Goshen
Department of Psychology, The Hebrew University, Jerusalem 91905, Israel
Psychoneuroendocrinology 32:1106-15. 2007..e., a slight increase in brain IL-1 levels can improve memory, whereas any deviation from the physiological range, either by excess elevation in IL-1 levels or by blockade of IL-1 signaling, results in impaired memory...
MR microscopy of magnetically labeled neurospheres transplanted into the Lewis EAE rat brainJeff W M Bulte
Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2195, USA
Magn Reson Med 50:201-5. 2003..The present results confirm that MR cell tracking can be used to guide the development of successful transplantation protocols...
Serial in vivo MR tracking of magnetically labeled neural spheres transplanted in chronic EAE miceTamir Ben-Hur
Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Magn Reson Med 57:164-71. 2007..The results are directly relevant for designing and optimizing cell therapies for MS, and achieving a better understanding of in vivo cell dynamics and cell-tissue interactions...
Nutritional status, cognition, and survival: a new role for leptin and AMP kinaseYossi Dagon
Department of Human Nutrition and Metabolism, Braun School of Public Health, Faculty of Medicine, Hebrew University Hadassah Medical School, Jerusalem 91120
J Biol Chem 280:42142-8. 2005..Should these findings extend to Man, then controlled activation of AMPK may improve neurodegenerative diseases, and leptin may have a new role in treating stress-associated malnutrition...
Axonal damage in multiple sclerosis: a complex issue in a complex diseaseNikolaos Grigoriadis
Department of Neurology, AHEPA University Hospital, Aristotle University of Thessaloniki, 1 Stilp Kyriakidi Str, 54636 Thessaloniki, Greece
Clin Neurol Neurosurg 106:211-7. 2004..Experimental data suggest that therapeutic interventions such as the induction of rapid remyelination may lead to the protection of axons. In addition to immunomodulation, future strategies for neuroprotection may be of great importance...
PKCepsilon induces astrocytic differentiation of multipotential neural precursor cellsRivka Steinhart
Gonda Goldschmied Medical Diagnosis Research Center, The Mina and Everard Goodman Faculty of Life Sciences, Bar Ilan University, Ramat Gan 52900, Israel
Glia 55:224-32. 2007..Our data suggest an important role of PKCepsilon in astrocytic differentiation and implicate Notch1 as a possible mediator of this effect...
