Eldad Ben-Chetrit

Summary

Affiliation: Hadassah University Hospital
Country: Israel

Publications

  1. ncbi request reprint The spectrum of MEFV clinical presentations--is it familial Mediterranean fever only?
    Eldad Ben-Chetrit
    Department of Medicine, Hadassah Hebrew University Hospital, Ein Kerem, Israel
    Rheumatology (Oxford) 48:1455-9. 2009
  2. pmc Familial mediterranean Fever and hypercoagulability
    Oshrat E Tayer-Shifman
    Rheumatology Unit, Division of Medicine, Hadassah Hebrew University Medical Center Jerusalem, Israel
    Mediterr J Hematol Infect Dis 3:e2011017. 2011
  3. doi request reprint Kimura's disease and Behcet's syndrome in the same family--are they associated?
    Eldad Ben-Chetrit
    Department of Medicine, Rheumatology Unit, Hadassah Hebrew University Medical Center Head, POB 12000, Jerusalem, Israel
    Joint Bone Spine 80:44-7. 2013
  4. pmc Relapsing macrophage activating syndrome in a 15-year-old girl with Still's disease: a case report
    Meir Mizrahi
    Department of Internal Medicine A, Hadassah Hebrew University Medical Center, POB 12000, Ein Kerem, Jerusalem, Israel
    J Med Case Reports 3:138. 2009
  5. ncbi request reprint The E148Q mutation in the MEFV gene: is it a disease-causing mutation or a sequence variant?
    E Ben-Chetrit
    Department of Medicine A, Hadassah Hebrew University, Jerusalem, Israel
    Hum Mutat 15:385-6. 2000
  6. ncbi request reprint The effects of colchicine and hydroxychloroquine on the cyclo-oxygenases COX-1 and COX-2
    Eldad Ben-Chetrit
    FMF Clinic, Department of Medicine, Hadassah University Hospital, POB 12000, Jerusalem, Israel
    Rheumatol Int 25:332-5. 2005
  7. ncbi request reprint The outcome of pregnancy in the wives of men with familial mediterranean fever treated with colchicine
    Eldad Ben-Chetrit
    Department of Medicine, Hadassah University Hospital, POB 12000, Jerusalem, Israel
    Semin Arthritis Rheum 34:549-52. 2004
  8. ncbi request reprint Cetirizine: An effective agent in Kimura's disease
    Eldad Ben-Chetrit
    Hadassah and Hebrew University Medical Center, Jerusalem, Israel
    Arthritis Rheum 53:117-8. 2005
  9. ncbi request reprint Mechanism of the anti-inflammatory effect of colchicine in rheumatic diseases: a possible new outlook through microarray analysis
    E Ben-Chetrit
    Department of Biochemistry, School of Medicine, Stanford University, CA, USA
    Rheumatology (Oxford) 45:274-82. 2006
  10. doi request reprint Pregnancy outcomes in women with familial Mediterranean fever receiving colchicine: is amniocentesis justified?
    Eli Ben-Chetrit
    Shaare Zedek Medical Center, Jerusalem, Israel
    Arthritis Care Res (Hoboken) 62:143-8. 2010

Collaborators

Detail Information

Publications30

  1. ncbi request reprint The spectrum of MEFV clinical presentations--is it familial Mediterranean fever only?
    Eldad Ben-Chetrit
    Department of Medicine, Hadassah Hebrew University Hospital, Ein Kerem, Israel
    Rheumatology (Oxford) 48:1455-9. 2009
    ..This gene is considered to be responsible only for FMF. In the present study, we tried to find out whether the MEFV gene is associated with or responsible for clinical conditions other than FMF...
  2. pmc Familial mediterranean Fever and hypercoagulability
    Oshrat E Tayer-Shifman
    Rheumatology Unit, Division of Medicine, Hadassah Hebrew University Medical Center Jerusalem, Israel
    Mediterr J Hematol Infect Dis 3:e2011017. 2011
    ..Colchicine which is the treatment of choice in FMF may also play a role in reducing inflammation thereby decreasing hypercoagulability...
  3. doi request reprint Kimura's disease and Behcet's syndrome in the same family--are they associated?
    Eldad Ben-Chetrit
    Department of Medicine, Rheumatology Unit, Hadassah Hebrew University Medical Center Head, POB 12000, Jerusalem, Israel
    Joint Bone Spine 80:44-7. 2013
    ..Recently, we encountered a family whose three siblings suffer from BD and an additional brother suffers from KD. This observation raised the question as to whether both diseases have a common underlying genetic basis...
  4. pmc Relapsing macrophage activating syndrome in a 15-year-old girl with Still's disease: a case report
    Meir Mizrahi
    Department of Internal Medicine A, Hadassah Hebrew University Medical Center, POB 12000, Ein Kerem, Jerusalem, Israel
    J Med Case Reports 3:138. 2009
    ..Cases of relapse of macrophage activating syndrome are relatively rare...
  5. ncbi request reprint The E148Q mutation in the MEFV gene: is it a disease-causing mutation or a sequence variant?
    E Ben-Chetrit
    Department of Medicine A, Hadassah Hebrew University, Jerusalem, Israel
    Hum Mutat 15:385-6. 2000
    ..Two healthy sibs of one of the E148Q homozygous were also homozygous E148Q. These observations are not in accordance to the notion that E148Q is a mutation causing disease...
  6. ncbi request reprint The effects of colchicine and hydroxychloroquine on the cyclo-oxygenases COX-1 and COX-2
    Eldad Ben-Chetrit
    FMF Clinic, Department of Medicine, Hadassah University Hospital, POB 12000, Jerusalem, Israel
    Rheumatol Int 25:332-5. 2005
    ..The aim of this study was to test whether colchicine and hydroxychloroquine have an inhibitory effect on cyclo-oxygenases (COX)...
  7. ncbi request reprint The outcome of pregnancy in the wives of men with familial mediterranean fever treated with colchicine
    Eldad Ben-Chetrit
    Department of Medicine, Hadassah University Hospital, POB 12000, Jerusalem, Israel
    Semin Arthritis Rheum 34:549-52. 2004
    ..To evaluate the outcome of pregnancies of normal women married to men with familial Mediterranean fever (FMF), some of whom took colchicine during the conception with their wives...
  8. ncbi request reprint Cetirizine: An effective agent in Kimura's disease
    Eldad Ben-Chetrit
    Hadassah and Hebrew University Medical Center, Jerusalem, Israel
    Arthritis Rheum 53:117-8. 2005
  9. ncbi request reprint Mechanism of the anti-inflammatory effect of colchicine in rheumatic diseases: a possible new outlook through microarray analysis
    E Ben-Chetrit
    Department of Biochemistry, School of Medicine, Stanford University, CA, USA
    Rheumatology (Oxford) 45:274-82. 2006
    ..We aim to study the molecular basis of colchicine action by analysing the effect of this drug on global gene expression of HUVEC (human umbilical vein endothelial cell line) cells...
  10. doi request reprint Pregnancy outcomes in women with familial Mediterranean fever receiving colchicine: is amniocentesis justified?
    Eli Ben-Chetrit
    Shaare Zedek Medical Center, Jerusalem, Israel
    Arthritis Care Res (Hoboken) 62:143-8. 2010
    ..To evaluate the outcome of pregnancies in women with familial Mediterranean fever (FMF) who are taking colchicine, and to reconsider the justification for amniocentesis in these women...
  11. ncbi request reprint Colchicine-induced leukopenia in a patient with familial Mediterranean fever: the cause and a possible approach
    E Ben-Chetrit
    Department of Medicine, Hadassah University Hospital, Jerusalem, POB12000, Israel
    Clin Exp Rheumatol 21:S38-40. 2003
    ..In the case of bone marrow suppression, colchicine should be continued with injections of G-CSF, whereas if the bone marrow is hypercellular it is suggested to use steroids and colchicine concomitantly...
  12. ncbi request reprint Molecular diagnosis of FMF: lessons from a study of 446 unrelated individuals
    E Ben-Chetrit
    Department of Medicine, Hadassah University Hospital in Ein Kerem, Jerusalem, Israel
    Clin Exp Rheumatol 20:S25-9. 2002
    ..Following the cloning of the gene associated with this disease (MEFV), genetic analysis of its mutations has become available, providing a new tool for the establishment or confirmation of the diagnosis of FMF...
  13. pmc Reproductive system in familial Mediterranean fever: an overview
    E Ben-Chetrit
    FMF Unit, Department of Medicine, Hadassah University Hospital, Jerusalem, Israel
    Ann Rheum Dis 62:916-9. 2003
    ..However, colchicine may induce oligospermia/azoospermia, but this effect is rare. Overall, colchicine treatment improves the prognosis of patients with FMF and increases their reproductive ability...
  14. pmc Amyloidosis induced, end stage renal disease in patients with familial Mediterranean fever is highly associated with point mutations in the MEFV gene
    E Ben-Chetrit
    Rheumatology Unit, Department of Medicine, Hadassah University Hospital, Jerusalem, Israel
    Ann Rheum Dis 60:146-9. 2001
    ..Recently the gene (MEFV) causing this disease was cloned and more than 18 mutations have been identified. The hypothesis that the development of amyloidosis is associated with one of these mutations was tested...
  15. ncbi request reprint Familial mediterranean fever and Behçet's disease--are they associated?
    Eldad Ben-Chetrit
    Department of Medicine, Hadassah University Hospital, Jerusalem, Israel
    J Rheumatol 29:530-4. 2002
    ..To test whether the coexistence of familial Mediterranean fever (FMF) and Behçet's disease (BD) is more frequent than expected and whether each disease affects the severity of the other...
  16. ncbi request reprint Familial Mediterranean fever (FMF) and renal AA amyloidosis--phenotype-genotype correlation, treatment and prognosis
    Eldad Ben-Chetrit
    Department of Medicine, FMF Clinic, Hadassah University Hospital, Jerusalem, Israel
    J Nephrol 16:431-4. 2003
    ..The risk of amyloidosis is increased in male FMF patients and in patients bearing polymorphism a/a in the SAA1 gene. Colchicine is the chosen drug for the treatment of FMF and can prevent amyloidosis...
  17. ncbi request reprint Major vessel thrombosis in Behçet's disease: the dilemma of anticoagulant therapy - the approach of rheumatologists from different countries
    Oshrat E Tayer-Shifman
    Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Clin Exp Rheumatol 30:735-40. 2012
    ..Our objective was to raise this therapeutic dilemma and to call for controlled studies to help establish guidelines to address this problem...
  18. ncbi request reprint Familial Mediterranean fever: a critical digest of the 2012-2013 literature
    Eli M Eisenstein
    Department of Pediatrics, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Clin Exp Rheumatol 31:103-7. 2013
    ..In this review, we summarise these and other salient findings from the recent FMF literature, and discuss their significance for the clinician. ..
  19. doi request reprint Laryngeal involvement in Behcet's disease--a challenge for treatment
    Menachem Gross
    Department of Otolaryngology Head and Neck Surgery, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Clin Rheumatol 32:S75-7. 2013
    ..Although some cases may still require surgical intervention, the therapeutic option of anti-TNF agents, specifically anti-TNF antibodies such as infliximab, may decrease the need for the surgical option...
  20. doi request reprint Pulmonary hemorrhage in antiphospholipid antibody syndrome
    Anat Scheiman Elazary
    Department of Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Rheumatol 39:1628-31. 2012
    ..To characterize the clinical manifestations of patients with antiphospholipid antibody syndrome (APS) and pulmonary hemorrhage (PH)...
  21. doi request reprint Serum levels of anti-streptolysin O antibodies: their role in evaluating rheumatic diseases
    Eli Ben-Chetrit
    Department of Medicine, Shaare Zedek Medical Center, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Int J Rheum Dis 15:78-85. 2012
    ..Family physicians measure serum levels of anti-streptolysin O antibodies (ASO) in the routine evaluation of patients with rheumatic conditions...
  22. doi request reprint Fatal nephrotic syndrome complicating allogeneic stem cell transplantation: a case report
    Iddo Z Ben-Dov
    Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Nephrol Dial Transplant 24:2946-9. 2009
    ..Physicians should be aware of the possibility that infections and inflammation accompanying the post-transplantation period may rarely promote the development of systemic amyloidosis or exacerbate silent pre-existing disease...
  23. ncbi request reprint Major bleeding caused by warfarin in a genetically susceptible patient
    Aharon Bloch
    Division of Medicine, Hadassah University Hospital, Jerusalem, Israel
    Pharmacotherapy 22:97-101. 2002
    ..The patient's enhanced sensitivity to warfarin 5 mg/day can be ascribed to decreased clearance of S-warfarin secondary to genetic alteration of the gene encoding CYP2C9, resulting in a life-threatening complication...
  24. ncbi request reprint The distribution of MEFV common mutations among Israeli patients with familial Mediterranean fever
    Eldad Ben-Chetrit
    Isr Med Assoc J 5:592-4. 2003
  25. ncbi request reprint Country as the primary risk factor for renal amyloidosis in familial Mediterranean fever
    Isabelle Touitou
    Hopital Arnaud de Villeneuve, Montpellier, France
    Arthritis Rheum 56:1706-12. 2007
    ..The aim of this study was to examine the controversial issue of amyloidosis susceptibility in FMF by determining the relative contributions of MEFV and numerous epidemiologic factors to the risk of renal amyloidosis...
  26. ncbi request reprint Effect of colchicine and cytokines on MEFV expression and C5a inhibitor activity in human primary fibroblast cultures
    Suzan Abedat
    Hematology Unit, Hadassah Hospitals, Mount Scopus, Israel
    Isr Med Assoc J 4:7-12. 2002
    ..A C5a inhibitor, previously detected in normal serosal fluids, was recently identified in serosal cultures as well, and was found to be deficient in serosal fluids and cultures obtained from FMF patients...
  27. ncbi request reprint Allogenic bone marrow transplantation: not a treatment yet for familial Mediterranean fever
    Isabelle Touitou
    Blood 102:409. 2003
  28. ncbi request reprint The rise and fall of FMF research--fifty years of publications
    Eli Ben-Chetrit
    Clin Exp Rheumatol 23:S3-7. 2005
  29. ncbi request reprint Peritoneal adhesions and intestinal obstructions in patients with familial Mediterranean fever--are they more frequent?
    Yackov Berkun
    Department of Pediatrics, Safra Children s Hospital, Sheba Medical Center, Tel Hashomer, Israel
    Semin Arthritis Rheum 36:316-21. 2007
    ..The aim of the study was to estimate the rate of spontaneous or postsurgical small-bowel obstruction (SBO) in FMF patients...
  30. ncbi request reprint Periodic fever in infants: familial Mediterranean fever only?
    Eldad Ben-Chetrit
    Isr Med Assoc J 5:739-40. 2003