Z Ackerman

Summary

Affiliation: Hadassah University Hospital
Country: Israel

Publications

  1. pmc Rosiglitazone and bezafibrate modulate gene expression in a rat model of non-alcoholic fatty liver disease - A historical prospective
    Hemda Schmilovitz-Weiss
    Division of Gastroenterology, Rabin Medical Center, Hasharon Hospital, Petach Tikva, Israel and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Lipids Health Dis 12:41. 2013
  2. doi request reprint Effects of antihypertensive and triglyceride lowering agents on splenocyte apoptosis in rats with Fatty liver
    Zvi Ackerman
    Department of Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Basic Clin Pharmacol Toxicol 113:37-42. 2013
  3. ncbi request reprint Renal effects of gentamicin in chronic bile duct ligated rats
    Zvi Ackerman
    Department of Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Dig Dis Sci 51:406-15. 2006
  4. doi request reprint Hepatic effects of rosiglitazone in rats with the metabolic syndrome
    Zvi Ackerman
    Department of Medicine, Mount Scopus Campus, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Basic Clin Pharmacol Toxicol 107:663-8. 2010
  5. doi request reprint Divergent effects of irritants on the gastric mucosa in rats during various stages after bile duct ligation
    Zvi Ackerman
    Department of Internal Medicine, Hadassah Hebrew University Medical Center, Mount Scopus Campus, Jerusalem, Israel
    J Gastroenterol Hepatol 25:1170-5. 2010
  6. ncbi request reprint Fructose-induced fatty liver disease: hepatic effects of blood pressure and plasma triglyceride reduction
    Zvi Ackerman
    Hebrew University Hadassah Medical Center, Jerusalem, Israel
    Hypertension 45:1012-8. 2005
  7. doi request reprint The prognostic value of changes in serum ferritin levels during therapy for hepatitis C virus infection
    Zvi Ackerman
    Department of Medicine, Mount Scopus Campus, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Med Virol 83:1262-8. 2011
  8. ncbi request reprint Experimental colitis in rats with portal hypertension and liver disease
    Zvi Ackerman
    Department of Medicine, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel
    Inflamm Bowel Dis 9:18-24. 2003
  9. ncbi request reprint Longitudinal prostaglandin E(2) generation in various organs during evolution of experimental portal hypertension
    Z Ackerman
    Department of Medicine, Hadassah University Hospital, Mount Scopus, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Prostaglandins Leukot Essent Fatty Acids 67:197-201. 2002
  10. ncbi request reprint Bone mineral metabolism and histomorphometry in rats with cholestatic liver disease
    Zvi Ackerman
    Department of Medicine, Hadassah University Hospital, Mount Scopus, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Liver 22:166-72. 2002

Collaborators

Detail Information

Publications25

  1. pmc Rosiglitazone and bezafibrate modulate gene expression in a rat model of non-alcoholic fatty liver disease - A historical prospective
    Hemda Schmilovitz-Weiss
    Division of Gastroenterology, Rabin Medical Center, Hasharon Hospital, Petach Tikva, Israel and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Lipids Health Dis 12:41. 2013
    ..Our aim was to characterize three genes involved in a rat model of non-alcoholic fatty liver disease and investigate the effect of rosiglitazone and bezafibrate...
  2. doi request reprint Effects of antihypertensive and triglyceride lowering agents on splenocyte apoptosis in rats with Fatty liver
    Zvi Ackerman
    Department of Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Basic Clin Pharmacol Toxicol 113:37-42. 2013
    ..NAFLD in FED rats is associated with an increase in splenic apoptosis. Agents administered to treat components of the MS in FED rats may lead to divergent changes in the splenic histology and splenocyte apoptosis...
  3. ncbi request reprint Renal effects of gentamicin in chronic bile duct ligated rats
    Zvi Ackerman
    Department of Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Dig Dis Sci 51:406-15. 2006
    ..In conclusion, gentamicin administration to rats with chronic BDL causes impairment of renal function. This happens only after the occurrence of simultaneous multiple insults to the renal protective mechanisms...
  4. doi request reprint Hepatic effects of rosiglitazone in rats with the metabolic syndrome
    Zvi Ackerman
    Department of Medicine, Mount Scopus Campus, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Basic Clin Pharmacol Toxicol 107:663-8. 2010
    ....
  5. doi request reprint Divergent effects of irritants on the gastric mucosa in rats during various stages after bile duct ligation
    Zvi Ackerman
    Department of Internal Medicine, Hadassah Hebrew University Medical Center, Mount Scopus Campus, Jerusalem, Israel
    J Gastroenterol Hepatol 25:1170-5. 2010
    ..In the present study we characterize GMD after intragastric instillation of either ethanol or hydrochloric acid (HCL), 3 and 21 days after the surgical procedure...
  6. ncbi request reprint Fructose-induced fatty liver disease: hepatic effects of blood pressure and plasma triglyceride reduction
    Zvi Ackerman
    Hebrew University Hadassah Medical Center, Jerusalem, Israel
    Hypertension 45:1012-8. 2005
    ..Drugs administered to treat various aspects of the metabolic syndrome could have hepatic effects. An increase in HIC in rats with NAFLD could be associated with increased hepatic fibrosis...
  7. doi request reprint The prognostic value of changes in serum ferritin levels during therapy for hepatitis C virus infection
    Zvi Ackerman
    Department of Medicine, Mount Scopus Campus, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    J Med Virol 83:1262-8. 2011
    ..49%, P = 0.039). Measuring serum ferritin levels during antiviral therapy in HCV patients who had an early virological response may assist in predicting sustained virological response...
  8. ncbi request reprint Experimental colitis in rats with portal hypertension and liver disease
    Zvi Ackerman
    Department of Medicine, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel
    Inflamm Bowel Dis 9:18-24. 2003
    ..We concluded that rats with experimental portal hypertension do not have increased damage when induced by either acetic acid or iodoacetamide...
  9. ncbi request reprint Longitudinal prostaglandin E(2) generation in various organs during evolution of experimental portal hypertension
    Z Ackerman
    Department of Medicine, Hadassah University Hospital, Mount Scopus, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Prostaglandins Leukot Essent Fatty Acids 67:197-201. 2002
    ..PGE(2) probably has no role in splanchnic hemodynamic changes during evolution of portal hypertension. Pulmonary PGE(2) generation may increase as a response to increased portal pressure, or to abdominal surgery...
  10. ncbi request reprint Bone mineral metabolism and histomorphometry in rats with cholestatic liver disease
    Zvi Ackerman
    Department of Medicine, Hadassah University Hospital, Mount Scopus, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Liver 22:166-72. 2002
    ..The etiology of osteopenia in cholestatic liver disease is uncertain. An animal model is needed in order to study the efficacy of therapeutic agents...
  11. ncbi request reprint Intrafamilial transmission of hepatitis C virus: a systematic review
    Z Ackerman
    Department of Medicine, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel
    J Viral Hepat 7:93-103. 2000
    ..In Japanese patients, transmission probably occurs in younger family members while, in non-Japanese patients, transmission probably occurs at an older age, after contact with an HCV-infected spouse...
  12. ncbi request reprint Effects of amlodipine, captopril, and bezafibrate on oxidative milieu in rats with fatty liver
    Zvi Ackerman
    Department of Medicine, Hadassah Hebrew University Medical Center, Mount Scopus Campus, Jerusalem 91240, Israel
    Dig Dis Sci 53:777-84. 2008
    ..Drugs administered to treat hypertension and hypertriglyceridemia could lead to a variety of changes in the hepatic oxidative, anti-oxidative milieu...
  13. pmc Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation
    I Magen
    Department of Human Nutrition and Metabolism, Braun School of Public Health, Hebrew University Medical Faculty, Jerusalem, Israel
    Br J Pharmacol 159:950-7. 2010
    ..We aimed to demonstrate the involvement of 5-HT(1A) receptors in the therapeutic effect of cannabidiol, a non-psychoactive constituent of Cannabis sativa, in a model of hepatic encephalopathy induced by bile-duct ligation (BDL) in mice...
  14. doi request reprint 2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist, in various rat tissues during the evolution of experimental cholestatic liver disease
    Yosefa Avraham
    Department of Human Nutrition and Metabolism, Braun School of Public Health, Hadassah Hebrew University Medical School, Jerusalem, Israel
    Prostaglandins Leukot Essent Fatty Acids 79:35-40. 2008
    ..Changes in tissue levels of 2-arachidonoylglycerol (2-AG), an endocannabinoid, during the evolution of bile duct ligation (BDL) may indicate that endocannabinoids have a role in the hemodynamic changes that occur in this condition...
  15. ncbi request reprint Enhanced gastric and duodenal platelet-activating factor and leukotriene generation in duodenal ulcer patients
    Z Ackerman
    Dept of Gastroenterology, Hadassah University Hospital, Hebrew University, Hadassah Medical School, Jerusalem, Israel
    Scand J Gastroenterol 25:925-34. 1990
    ..These results thus suggest that PAF, LTB4, and LTC4 may have a role in the pathogenesis of duodenal ulcer, and therefore their modulation may have therapeutic benefits...
  16. ncbi request reprint Effect of hepatic iron concentration reduction on hepatic fibrosis and damage in rats with cholestatic liver disease
    Gil Peretz
    Department of Internal Medicine, Hebrew University Hadassah Medical Center, Mount Scopus Campus, PO Box 24035, Jerusalem 91240, Israel
    World J Gastroenterol 12:240-5. 2006
    ..To assess the effect of iron reduction after phlebotomy in rats with "normal" hepatic iron concentration (HIC) on the progression of hepatic fibrosis, as a result of bile duct ligation (BDL)...
  17. ncbi request reprint Human parathyroid hormone 1-34 prevents bone loss in experimental biliary cirrhosis in rats
    Rivka Dresner-Pollak
    Endocrinology and Metabolism Service, Department of Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Gastroenterology 134:259-67. 2008
    ..The effect of intermittent administration of human parathyroid hormone (hPTH) 1-34 on bone mass and architecture in bile duct-ligated (BDL) rats was studied...
  18. doi request reprint The clinical spectrum of cytomegalovirus colitis in adults
    Y Einbinder
    Department of Internal Medicine, Mount Scopus Campus, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Aliment Pharmacol Ther 27:578-87. 2008
    ..Colonic cytomegalovirus reactivation rarely occurs in adults without inflammatory bowel disease or a known immunosuppressive state...
  19. doi request reprint Massive bleeding from ectopic varices in the postpartum period: rare but serious complication in women with portal hypertension
    Hadas Rosenfeld
    Department of Internal Medicine, Mount Scopus Campus, Hadassah Hebrew University Medical Center, Jerusalem 91240, Israel
    Eur J Gastroenterol Hepatol 21:1086-91. 2009
    ..On the basis of a literature review, we constructed an algorithm that includes instructions on how to handle women with PHT during the various stages of pregnancy and labor...
  20. doi request reprint Declining frequency of liver enzyme abnormalities with statins: experience from general practice in Jerusalem
    Alexander Kiderman
    Division of Family, Briut Clalit Services, Hadassah Hebrew University Medical Center, Ein Kerem, Jerusalem, Israel
    Eur J Gastroenterol Hepatol 20:1002-5. 2008
    ..Drug effects, including adverse reactions, may depend on genetics and environment. We investigated liver enzymes in relation to statin treatment in a northeast Jerusalem Jewish community...
  21. ncbi request reprint Expression of serum amyloid A, in normal, dysplastic, and neoplastic human colonic mucosa: implication for a role in colonic tumorigenesis
    Orit Gutfeld
    Department of Oncology, Hadassah Hebrew University Medical Center, Mount Scopus, Jerusalem 91240, Israel
    J Histochem Cytochem 54:63-73. 2006
    ..These findings indicate local and differential expression of SAA in human colon cancer tissues and suggest its role in colonic tumorigenesis...
  22. ncbi request reprint Treatment of chronic hepatitis C virus infection via antioxidants: results of a phase I clinical trial
    Alla Melhem
    Liver Unit, Department of Medicine, Hebrew University, Hadassah Medical Center, Jerusalem, Israel
    J Clin Gastroenterol 39:737-42. 2005
    ..Previous trials suggested that antioxidative therapy may have a beneficial effect on patients with chronic HCV infection...
  23. ncbi request reprint Role of Helicobacter pylori infection in complications from Meckel's diverticulum
    Zvi Ackerman
    Department of Medicine, Hadassah University Hospital, Mount Scopus, Hebrew University Hadassah Medical School, Jerusalem, Israel
    Dig Dis Sci 48:1068-72. 2003
    ..In conclusions, Helicobacter pylori colonizes heterotopic gastric mucosa with Meckel's diverticulum, but probably has a minor role in the complications of Meckel's diverticulum...
  24. ncbi request reprint Low alanine aminotransferase activity in older people is associated with greater long-term mortality
    Eran Elinav
    Department of Medicine, Hadassah Hebrew University Medical Center, Mount Scopus Campus, Jerusalem, Israel
    J Am Geriatr Soc 54:1719-24. 2006
    ..To find possible association between liver enzymes and mortality in older people...
  25. ncbi request reprint Experimental cholestatic liver disease through bile-duct ligation in rats results in skeletal fragility and impaired osteoblastogenesis
    Miron Weinreb
    Department of Oral Biology, Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv 69978, Israel
    J Hepatol 40:385-90. 2004
    ....