Research Topics | Ian M GralnekSummaryCountry: Israel Publications
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Management of acute bleeding from a peptic ulcerIan M Gralnek
Department of Gastroenterology and Gastrointestinal Outcomes Unit, Rambam Health Care Campus and Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
N Engl J Med 359:928-37. 2008
Capsule endoscopy in acute upper gastrointestinal hemorrhage: a prospective cohort studyI M Gralnek
Department of Gastroenterology, Rambam Health Care Campus, Haifa, Israel
Endoscopy 45:12-9. 2013..Capsule endoscopy may play a role in the evaluation of patients presenting with acute upper gastrointestinal hemorrhage in the emergency department...- Small bowel capsule endoscopy impacts diagnosis and management of pediatric inflammatory bowel disease: a prospective studyIan M Gralnek
Department of Gastroenterology, Bruce and Ruth Rappaport Faculty of Medicine, Technion Israel Institute of Technology, GI Outcomes Unit, Rambam Health Care Campus, Haifa, Israel
Dig Dis Sci 57:465-71. 2012..Accurately classifying inflammatory bowel disease (IBD) type in pediatric patients may impact medical decision-making, direct therapy, and improve outcomes... - Esomeprazole versus other proton pump inhibitors in erosive esophagitis: a meta-analysis of randomized clinical trialsIan M Gralnek
Rambam Medical Center, Department of Gastroenterology, GI Outcomes Unit, Faculty of Medicine, Technion Institute of Technology, Haifa, Israel
Clin Gastroenterol Hepatol 4:1452-8. 2006..We performed a meta-analysis to calculate the pooled effect of esomeprazole on healing rates, symptom relief, and adverse events versus competing PPIs in EE... - Endoscopic research: funding opportunities and mechanisms from the ASGE and beyondIan M Gralnek
Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
Gastrointest Endosc 64:S16-8. 2006 - The cost-effectiveness and budget impact of intravenous versus oral proton pump inhibitors in peptic ulcer hemorrhageBrennan M R Spiegel
Division of Gastroenterology, Veteran's Administration Greater Los Angeles Healthcare System, California, USA
Clin Gastroenterol Hepatol 4:988-997. 2006..CONCLUSIONS: The higher effectiveness of IV PPI therapy may not offset its increased costs vs PO PPI therapy in ulcer hemorrhage. The managed care budget impact of IV PPIs exceeds most benchmarks... - Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placeboJay L Goldstein
Department of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, USA
Clin Gastroenterol Hepatol 3:133-41. 2005..In a multicenter, double-blind, placebo-controlled trial with video capsule endoscopy (VCE) we prospectively evaluated the incidence of small bowel injury in healthy subjects treated with celecoxib compared to naproxen plus omeprazole... - Incremental value of upper endoscopy for triage of patients with acute non-variceal upper-GI hemorrhageIan M Gralnek
Department of Medicine, VA Greater Los Angeles Healthcare System, and Department of Medicine, CURE Digestive Diseases Research Center, UCLA Center for the Health Sciences, David Geffen School of Medicine at UCLA, California 90073, USA
Gastrointest Endosc 60:9-14. 2004..Use of the clinical and complete Rockall Scores sequentially, with consideration of outpatient care for patients at identified as low risk, is recommended... - Randomized trial of medical or endoscopic therapy to prevent recurrent ulcer hemorrhage in patients with adherent clotsDennis M Jensen
CURE Digestive Disease Research Center, UCLA School of Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, California 90073, USA
Gastroenterology 123:407-13. 2002..Our purpose was to test the hypothesis that patients treated with combination endoscopic therapy would have significantly lower rebleeding rates than those treated with medical therapy... - Are physician-derived disease severity indices associated with health-related quality of life in patients with end-stage liver disease?Fasiha Kanwal
VA Greater Los Angeles Health Care System, David Geffen School of Medicine at UCLA, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA
Am J Gastroenterol 99:1726-32. 2004..However, there are no data evaluating the associations between MELD scores and patient reports of health-related quality of life (HRQOL)... - Utilization of health care resources for low-risk patients with acute, nonvariceal upper GI hemorrhage: an historical cohort studyGareth S Dulai
Department of Medicine, Division of Digestive Diseases, UCLA School of Medicine, Los Angeles, CA 90073, USA
Gastrointest Endosc 55:321-7. 2002..The Rockall score has potential as a clinically based concurrent decision rule to improve the quality of care by finding those patients less likely to require intensive health care services... - An evaluation of endoscopic indications and findings related to nonvariceal upper-GI hemorrhage in a large multicenter consortiumBrintha K Enestvedt
Department of Internal Medicine, Oregon Health and Sciences University, Portland, Oregon 97214, USA
Gastrointest Endosc 67:422-9. 2008..There is limited information about patients with UGIH who are evaluated by endoscopy at nonacademic settings, which comprise the majority of endoscopic practices in the United States... - Hospital care for low-risk patients with acute, nonvariceal upper GI hemorrhage: a comparison of neighboring community and tertiary care centersTommy T Oei
VA Greater Los Angeles Healthcare System, California 90073, USA
Am J Gastroenterol 97:2271-8. 2002..This observed variation in the process of care for populations with similar disease severity and outcomes suggests an opportunity for evidence-based interventions aimed at improving the efficiency of care... - Portal hypertensive enteropathy in a patient with polycystic liver disease: a unique endoscopic findingShou-Jiang Tang
Division of Digestive Diseases, Center for Health Sciences, University of California at Los Angeles (UCLA, USA
Gastrointest Endosc 56:924-6. 2002 - The cost-effectiveness of cyclooxygenase-2 selective inhibitors in the management of chronic arthritisBrennan M R Spiegel
Veterans Administration Greater Los Angeles Healthcare System, David Geffen School of Medicine at University of California, CURE Digestive Diseases Research Center, Los Angeles, CA 90073, USA
Ann Intern Med 138:795-806. 2003..However, coxibs may provide an acceptable incremental cost-effectiveness ratio in the subgroup of patients with a history of bleeding ulcers... - Comparing rates of dyspepsia with Coxibs vs NSAID+PPI: a meta-analysisBrennan M R Spiegel
Division of Gastroenterology and Hepatology, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, Calif 90073, USA
Am J Med 119:448.e27-36. 2006.... - Systematic review of the effects of n-3 fatty acids in inflammatory bowel diseaseCatherine H Maclean
Southern California Evidence Based Practice Center, Santa Monica, CA 90407 2138, USA
Am J Clin Nutr 82:611-9. 2005..n-3 Fatty acids are purported to have health effects in patients with inflammatory bowel disease (IBD), but studies have reported mixed results... - Combination endoscopic band ligation and sclerotherapy compared with endoscopic band ligation alone for the secondary prophylaxis of esophageal variceal hemorrhage: a meta-analysisHetal A Karsan
VA Greater Los Angeles Healthcare System, David Geffen School of Medicine at UCLA, Center for the Health Sciences, Division of Digestive Diseases, Los Angeles, California 90073, USA
Dig Dis Sci 50:399-406. 2005..Moreover, combination EBL and sclerotherapy had more esophageal stricture formation than EBL alone... - Management of acute nonvariceal upper gastrointestinal hemorrhage: comparison of an American and a Canadian medical centreLaura E Targownik
Veterans Affairs Greater Los Angeles Health Care System, California, USA
Can J Gastroenterol 17:489-95. 2003..The aim of the present study was to compare the structure, process and outcomes of care between a Canadian and an American tertiary care medical centre in the management of acute nonvariceal UGIH... - Colonic stent vs. emergency surgery for management of acute left-sided malignant colonic obstruction: a decision analysisLaura E Targownik
Division of Digestive Diseases, School of Medicine, UCLA Center for the Health Sciences, University of California-Los Angeles, Los Angeles, CA 90095, USA
Gastrointest Endosc 60:865-74. 2004..Our findings suggest that colonic stent insertion should be offered, whenever feasible, as a bridge to elective surgery in patients presenting with malignant colonic obstruction... - Outpatient management of "low-risk" nonvariceal upper GI hemorrhage. Are we ready to put evidence into practice?Ian M Gralnek
Gastrointest Endosc 55:131-4. 2002